The genomic footprints of migration: how ancient DNA reveals our history of mobility by Matthew P. Williams, Christian D. Huber

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Population structure and mitogenomic analyses reveal dispersal routes of Macrobrachium nipponense in China by Penghui Luo, Yiting Jin, Ting Zhao, Chao Bian, Zhimin Lv, Na Zhou, Jianguang Qin, Shengming Sun

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Chang’E-5 radar reveals fast regolith production at landing site by Gang Yu, Yong Pang, Menglong Xu, Yuqi Qian

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Ischemic stroke revealing diffuse cerebral proliferative angiopathy—A case report by Amal Mojahid, Nadia El Mahi, Hajar Siouri, Hicham Benramdane, Aicha Laabadi, Hamid Ziani, Nasri Siham, Imane Kamaoui, Imane Skiker

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Integrative Multi-omics and Network Pharmacology Reveal the Mechanisms of Xiaoyaosan in Treating Depression by Huizheng Zhu, Shengyu Cai, Shaoyi Huang, Liyuan Su, Siwei Zhang

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Genome wide analyses reveal the population distinctiveness of the ‘Nera del Mela’ sheep by Giorgio Chessari, Andrea Criscione, Marco Tolone, Alessandro Zumbo, Silvia Riggio, Ilaria Rizzuto, Angelo Moscarelli, Vito Macaluso, Baldassare Portolano, Maria Teresa Sardina, Salvatore Mastrangelo

“…Genetic diversity indices, and inbreeding estimated from runs of homozygosity (FROH) revealed a moderate level of variability. Runs of homozygosity islands mapped candidate genes involved in the adaptation to local environment and immune response. …”
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Lipidomics reveals potential biomarkers and pathophysiological insights in the progression of diabetic kidney disease by Xiaozhen Guo, Zixuan Zhang, Cuina Li, Xueling Li, Yutang Cao, Yangyang Wang, Jiaqi Li, Yibin Wang, Kanglong Wang, Yameng Liu, Cen Xie, Yifei Zhong

“…Results: Lipid profiling revealed elevated levels of certain lysophosphatidylethanolamines (LPEs), phosphatidylethanolamines (PEs), ceramides (Cers), and diacylglycerols (DAGs) in the DM-DKD transition, while most LPEs, lysophosphatidylcholines (LPCs), along with several monoacylglycerol (MAG) and triacylglycerols (TAGs), increased further from DKD-E to DKD-A. …”
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Phylogenomic Analysis Reveals Evolutionary Relationships of Tropical Drosophilidae: From Drosophila to Scaptodrosophila by Matsapume Detcharoen, Pairot Pramual, Areeruk Nilsai

“…Phylogenetic analyses of 13 mitochondrial protein‐coding genes revealed well‐supported evolutionary relationships, with Scaptodrosophila forming a distinct lineage and several Drosophila subgroups, such as ananassae, montium, and melanogaster, exhibiting monophyly. …”
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Mapping mitochondrial morphology and function: COX-SBFSEM reveals patterns in mitochondrial disease by Julie Faitg, Tracey Davey, Ross Laws, Conor Lawless, Helen Tuppen, Eric Fitton, Doug Turnbull, Amy E. Vincent

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Imaging flow cytometry reveals divergent mitochondrial phenotypes in mitochondrial disease patients by Irena.J.J. Muffels, Richard Rodenburg, Hanneke L.D. Willemen, Désirée van Haaften-Visser, Hans Waterham, Niels Eijkelkamp, Sabine A. Fuchs, Peter M. van Hasselt

“…A multimodal functional assessment may better reveal underlying disease patterns. Using imaging flow cytometry (IFC), we evaluated mitochondrial fragmentation, swelling, membrane potential, reactive oxygen species (ROS) production, and mitochondrial mass in fibroblasts from 31 mitochondrial disease patients. …”
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Genome assembly of Stewartia sinensis reveals origin and evolution of orphan genes in Theaceae by Lin Cheng, Qunwei Han, Yanlin Hao, Zhen Qiao, Mengge Li, Daliang Liu, Hao Yin, Tao Li, Wen Long, Shanshan Luo, Ya Gao, Zhihan Zhang, Houlin Yu, Xinhao Sun, Hao Li, Yiyong Zhao

“…Comparative genomic analysis revealed the absence of recent whole-genome duplication events in the Theaceae ancestor, highlighting tandem duplications as the predominant mechanism of gene expansion. …”
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Epigenomic profiling of papillary thyroid carcinoma reveals distinct subtypes with clinical implications by Yeongun Lee, Hyo Jin Park, Jin Seok Lee, Ho Jung Jeong, Su Min Kim, Minjeong Cho, Wonjin Woo, So Hee Dho, Seok-Mo Kim, Lark Kyun Kim

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Untargeted metabolomics reveals homogeneity and heterogeneity between physiological and pathological ovarian aging by Lihua Zeng, Yunyi Liang, Lizhi Huang, Zu’ang Li, Manish Kumar, Xiasheng Zheng, Jing Li, Songping Luo, Ling Zhu

“…Abstract Background Ovarian aging is the main cause of reduced reproductive life span, yet its metabolic profiles remain poorly understood. This study aimed to reveal the metabolic homogeneity and heterogeneity between physiological and pathological ovarian aging. …”
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Whole blood transcriptomics analysis of Indonesians reveals translocated and pathogenic microbiota in blood by Katalina Bobowik, Muhamad Fachrul, Chelzie Crenna Darusallam, Pradiptajati Kusuma, Herawati Sudoyo, Clarissa A. Febinia, Safarina G. Malik, Christine A. Wells, Irene Gallego Romero

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The Trypanosome Exocyst: A Conserved Structure Revealing a New Role in Endocytosis. by Cordula M Boehm, Samson Obado, Catarina Gadelha, Alexandra Kaupisch, Paul T Manna, Gwyn W Gould, Mary Munson, Brian T Chait, Michael P Rout, Mark C Field

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Transcriptome analysis reveals genes associated with the bitter-sweet trait of apricot kernels by Yu Zhang, Wenquan Bao, Ta-na Wuyun, Mengzhen Huang, Chen Chen, Dun Ao, Rong Yang, Haiguang Huang, Lin Wang

“…Transcriptome analysis revealed 6,942 differentially expressed genes (DEGs), with a subset of 38 DEGs specifically enriched in the cyanoamino acid metabolic pathway. …”
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Four near-complete genome assemblies reveal the landscape and evolution of centromeres in Salicaceae by Yubo Wang, Lulu Zhao, Deyan Wang, Kai Chen, Tiannan Luo, Jianglin Luo, Chengzhi Jiang, Zhoujian He, Heng Huang, Jiaxiao Xie, Yuanzhong Jiang, Jianquan Liu, Tao Ma

“…Comparative analysis reveals that these centromeric repeats are extensively expanded and interspersed with satellite arrays in a species-specific and chromosome-specific manner, driving rapid turnover of centromeres both in sequence compositions and genomic locations in the Salicaceae. …”
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Proteomics and transcriptomics combined reveal specific immunological markers in autoimmune thyroid disease by Xia Chen, Hui Chen

“…Enrichment analysis revealed that these differentially expressed genes and proteins are primarily associated with immune function, antigen-antibody binding, and alterations in immune cells. …”
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Seasonal transcriptomic shifts reveal metabolic flexibility of chemosynthetic symbionts in an upwelling region by Isidora Morel-Letelier, Benedict Yuen, Luis H. Orellana, A. Carlotta Kück, Yolanda E. Camacho-García, Minor Lara, Matthieu Leray, Laetitia G. E. Wilkins

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Comparative genomics of Leptospira santarosai reveals genomic adaptations in bovine genital strains by Maria Isabel Nogueira Di Azevedo, Frederico Kremer, Camila Ezepha, João Pedro Gomes Greco, Isadora Cosenza Vieira da Silva, Pascale Bourhy, Walter Lilenbaum

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