What do the sustainable development goals reveal, and are they sufficient for sustainable development? by Bing Wang, Tianchi Chen

“…Finally, despite the novelty of EFP and HPI, they cannot reveal the entire development story. SDGs require embracing more such indicators to enrich the value bases of development and achieve a sustainable future.…”
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Imaging phenotype reveals that disulfirams induce protein insolubility in the mitochondrial matrix by Ken Ohno, Hisashi Murakami, Naohisa Ogo, Akira Asai

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Phylogenetic analysis of pathogenic algae reveals lineage-dependent patterns of phagocytosis by Christopher D. Shave, Mohammed J. A. Haider, Chinaemerem U. Onyishi, Megan C. McDonald, Leanne Stones, Tomasz Jagielski, Robin C. May

“…Together, these findings reveal the interaction between pathogen phylogeny and host immune response, revealing ways to identify new therapeutic targets in the future.IMPORTANCEProtothecosis is a rare algal infection caused by members of the genus Prototheca, which is comprised of unusual non-photosynthetic algae. …”
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Genome-wide comparison reveals large structural variants in cassava landraces by Michael Landi, Anna Vittoria Carluccio, Trushar Shah, Adnan Niazi, Livia Stavolone, Laurent Falquet, Andreas Gisel, Erik Bongcam-Rudloff

“…By mapping short-read sequencing data from 16 cassava landraces to TMEB117 chromosome 12, we observed variability in read mapping, suggesting that while all genotypes contain the insertion region, some exhibit missing segments or sequence differences. Further analysis revealed two unique genes associated with deacetylase activity, HDA14 and SRT2, within the insertion. …”
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Genome Mining Reveals Rifamycin Biosynthesis in a Taklamakan Desert Actinomycete by Xinrong Luo, Zhanwen Liu, Xiaoxia Luo, Zhanfeng Xia, Chuanxing Wan, Haoxin Wang, Lili Zhang

“…TRM71106, a rare actinomycete isolated from the Taklamakan Desert, through integrated genomic and metabolomic approaches. Genome sequencing revealed 45 secondary metabolic BGCs, including BGC38 showing 65% nucleotide similarity to the rifamycin BGC. …”
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Prospecting environmental mycobacteria: combined molecular approaches reveal unprecedented diversity. by Alessandra Pontiroli, Tanya T Khera, Brian B Oakley, Sam Mason, Scot E Dowd, Emma R Travis, Girum Erenso, Abraham Aseffa, Orin Courtenay, Elizabeth M H Wellington

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Revealing the Origins of Galactic Globular Clusters via their Mg–Al Abundances by Shihui Lin, Baitian Tang, Genghao Liu, José G. Fernández-Trincado, Douglas Geisler, Guy Worthey, Dante Minniti

“…Identifying their origins is crucial for revealing galaxy properties at early times. Traditional classification methods relying on dynamical properties face inherent uncertainties stemming from the evolving Galactic potential and complex merger histories. …”
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Revealing and explaining deep structure via Qualitative Research in Medicine and Healthcare by Warren Bareiss

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Mucosal microbiota signatures reveal diagnostic insights in chronic liver disease by Sadık Dinçer, Yakup Ülger, Anıl Delik

“…Family-level comparisons revealed elevated Enterobacteriaceae in CLD, while Ruminococcaceae and Veillonellaceae were relatively preserved in controls. …”
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Revealing disorder parameter and deformation electron density using electron diffraction by Weixiao Lin, Zefan Xue, Wenjun Cui, Andreas Kulovits, Hao Ren, Wen Zhao, Jinsong Wu, Gustaaf Van Tendeloo, Jörg Wiezorek, Xiahan Sang

“…Here, a multi-beam off-zone axis CBED technique combined with a coherent potential approximation in Bloch wave formalism is used to simultaneously determine chemical disorder parameters, deformation electron density ∆ρ EXP, and Debye-Waller factors (DWF) in both chemically-ordered L10 FePd and chemically-disordered γ-phase FePd solid solution. The CBED results reveal that chemical disordering significantly increases DWFs while having a negligible impact on ∆ρ EXP. …”
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Whole-genome resequencing reveals collagen-related genes in Kele pigs. by Yu Dan Zhang, Wei Yuan, Huan Bi, Xiao Yang, Yi Yu Zhang, Wei Chen

“…<h4>Results</h4>Our sequencing results revealed that 241.04 G of clean data, Q30 reached 93.96% and the average coverage depth was 9.04×. …”
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Quantifying the mRNA epitranscriptome reveals epitranscriptome signatures and roles in cancer by Ying Feng, Xiaoli He, Mingxin Guo, Ying Tang, Guantong Qi, Qian Huang, Wenran Ma, Hong Chen, Yifan Qin, Ruiqi Li, Jin Wang, Yu Liu

“…Transcriptomic and proteomic analyses further revealed the molecular mechanisms underlying the phenotypic variation.…”
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Revealing lactylation-mediated mechanisms and hub genes in heart failure pathogenesis by Hongguang Xie, Yiqiang Wang, Xing Zhu, Lili Zhang, Heli Niu, Hongguang Jin

“…Immune infiltration analysis further revealed that these Lcy-HF hub genes are associated with macrophage polarization.ConclusionsLactylation plays a crucial role in the pathogenesis of HF, with genes such as GATA2, HBB, JAK2, STAT2, STAT4, and WARS2 emerging as potential lactylation biomarkers for HF identification. …”
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Single cell analysis and bioinformatics reveal pyroptosis mechanisms in hepatocellular carcinoma by Wei Luo, JunxiaWang, Hongfei Wang, Fei Liu, Taiwei Yang, Zhongjun Wu, Wubin Guo

“…The cellular clustering of single cells revealed the infiltration of immune cells, especially the polarization of macrophages, which plays an important role. …”
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CONCEALING AND REVEALING: REPRESSION IN A PALE VIEW OF HILLS AND THE REMAINS OF THE DAY by Blerina Zaimi, Entela Kushta

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Revealing Microplastic Contamination in Mangrove Sediments from Setiu Wetlands, Malaysia by Nur Syafiqah Mohd Maulana, Muhammad Shiddiq Zulkifli, Aina Arifah Khalid, Rohani Shahrudin, Sabiqah Tuan Anuar, Maisarah Jaafar, Effi Helmy Ariffin

“…Over 80% of the microplastics were fibers, primarily transparent and black, with surface analysis revealing signs of environmental degradation, including cracks and pits. …”
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Chronic rhinosinusitis revealing a nasal sarcoidosis: A case report by Abdelmonim Belkacemi, Saad Bouchlarhem, Achraf Amine Sbai, Drissia Belfadil, Azeddine Lachkar, Fahd El Ayoubi El Idrissi

“…Diagnosis relies on imaging studies, which may reveal mucosal thickening or destructive lesions, and histopathological confirmation through biopsy. …”
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Idiopathic Secondary Eosinophilia: Revealing Cerebral Aneurysms as a Vascular Complication by Rita D. Moncayo MD, Mukhammad B. Sultanov MD, Mojdeh Yadollahikhales BS, May Thet Hmu Tun MD, Omar P. Azar MD, Meredith E. Pittman MD, Navjot K. Somal MD

“…The case centers on a 31-year-old female who presented with leg pain, a purpuric rash, and gastrointestinal symptoms following an uncomplicated pregnancy. The skin biopsy revealed perivascular and interstitial dermatitis with a significant eosinophilic infiltration of unclear etiology. …”
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Machine Learning Reveals Aneuploidy Characteristics in Cancers: The Impact of BEX4 by Aizhong Xu, Jianjun Liu, Li Tong, Tingting Shen, Songlin Xing, Yujie Xia, Bosen Zhang, Zihao Wu, Wenkang Yuan, Anhai Yu, Zijie Kan, Wenqi Yang, Chao Zhang, Chong Zhang

“…The competitive endogenous RNA (ceRNA)-Genes network revealed that hub genes, co-regulated by hsa-miR-425-5p, hsa-miR-200c-3p, and others, regulate microtubules, centrosomes, and microtubule cytoskeleton. …”
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Autoantibodies Targeting Vinculin Reveal Novel Insight into the Mechanisms of Autoimmune Podocytopathies by Hanyan Meng, Dongjie Wang, Chen Zheng, Chao Zhou, Xinrui Mao, Jinglan Gu, Xiaohui Qiao, Fei Liu, Jingjing Wang, Haidong Fu, Jianhua Mao, Qing Ye

“…Transcriptome sequencing of renal tissues revealed up-regulation of inflammation, immune responses, cytokine activities, and B cell activation pathways in the immunized mice, while cytoskeleton-related functions were down-regulated. …”
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