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  1. 421

    Revealing propionate metabolism-related genes in glioblastoma and investigating their underlying mechanisms by Yuchen Sun, Huijuan Wang

    Published 2025-04-01
    “…GSEA showed enrichment of immune response activation and cell cycle regulatory pathways. qRT-PCR validation showed up-regulation of PNPLA3 and SARDH, and down-regulation of ADSL, in tumor tissues.ConclusionsThis study identified six PMRGs (SARDH, ACHE, ADSL, PNPLA3, MAPK1 and SREBF2) as potential prognostic biomarkers for glioblastoma. These biomarkers reveal the role of propionate metabolism in the progression of glioblastoma and may serve as important indicators of patient prognosis and treatment strategies.…”
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    Leveraging psychometric properties of Ubuntu measures to reveal its structural components by Renier Steyn, Pumela Msweli

    Published 2025-05-01
    “…Five Ubuntu measures were identified, revealing similar constructs but inconsistent terminology. …”
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    Comparative genomics reveals carbohydrate enzymatic fluctuations and herbivorous adaptations in arthropods by Dairon Ojeda-Martinez, Isabel Diaz, M. Estrella Santamaria, Félix Ortego

    Published 2024-12-01
    “…Results: We analyzed 815 arthropod proteomes and identified a total of 268,171 carbohydrate-active modules. Our findings revealed a strong correlation between enzymatic content and feeding habits, with herbivorous species possessing significantly higher enzyme levels. …”
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    Molecular phylogeny and morphology reveal four novel species in Cordycipitaceae in China by Jing Bu, De-Ping Wei, Zheng-Hui Liu, Yang Yang, Zhong-Liang Liu, Ji-Chuan Kang, Xing-Can Peng, Shi-Wen Xie, He-Gui Zhang, Zhang-Jiang He, Shi-Ke Huang, Xian Zhang, Kevin D. Hyde, Nalin N. Wijayawardene, Ting-Chi Wen

    Published 2025-04-01
    “…In this study, phylogenetic analyses using nrLSU, ITS, nrSSU, 3P_TEF, rpb1, and rpb2 revealed a new species, Pleurodesmospora sanduensis, and a new collection of Akanthomyces baishanensis. …”
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  19. 439

    Revealing Pathway Dynamics in Heart Diseases by Analyzing Multiple Differential Networks. by Xiaoke Ma, Long Gao, Georgios Karamanlidis, Peng Gao, Chi Fung Lee, Lorena Garcia-Menendez, Rong Tian, Kai Tan

    Published 2015-06-01
    “…By analyzing M-DMs that are present in multiple conditions, we revealed dynamic changes in pathway activity and connectivity across heart failure conditions. …”
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  20. 440

    Transcriptomic and Metabolomic Analysis Reveals Improved Fruit Quality in Grafted Watermelon by Kang Ning, Xiaoqi Cai, Leiyan Yan, Weixin Zhou, An Xie, Yuhong Wang, Pei Xu

    Published 2024-11-01
    “…KO (Kyoto Encyclopedia of Genes and Genomes Orthology) analysis revealed that the DAMs were mainly enriched in the flavone and flavonol biosynthesis pathway. …”
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