Shared early molecular mechanisms revealed in P301S and 5xFAD Alzheimer’s disease mouse models by Huda Suloh, Shashank Kumar Ojha, Maryam Kartawy, Wajeha Hamoudi, Manish Kumar Tripathi, Wisam Bazbaz, Nofar Schottlender, Uri Ashery, Igor Khaliulin, Haitham Amal

“…Additionally, the phosphorylation levels of the mTOR signaling components revealed hyperactivation of this pathway in P301S mice. …”
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ICT and trade competitiveness in West Africa: the mediating role of revealed comparative advantage in the non-alcoholic beverage sector by Nnanna P. Azu, Aburime Ehimare, Hassan P. Abdullahi

“…Abstract This study examines the impact of information and communication technology (ICT) and revealed comparative advantage (RCA) on non-alcoholic trade in West Africa. …”
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Extensive novel diversity and phenotypic associations in the dromedary camel microbiome are revealed through deep metagenomics and machine learning by Fathi A. Mubaraki

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Return of the founder Chikungunya virus to its place of introduction into Brazil is revealed by genomic characterization of exanthematic disease cases by Zuinara Pereira Gusmão Maia, Felicidade Mota Pereira, Rodrigo Fabiano do Carmo Said, Vagner Fonseca, Tiago Gräf, Fernanda de Bruycker Nogueira, Vanessa Brandão Nardy, Joilson Xavier, Maricelia Lima Maia, André L. Abreu, Carlos F. Campelo de Albuquerque, Wanderson Kleber Oliveira, Julio Croda, Ana Maria Bispo de Filippis, Rivaldo Venancio Cunha, Jose Lourenço, Tulio de Oliveira, Nuno Rodrigues Faria, Luiz Carlos Junior Alcantara, Marta Giovanetti

“…Using a combination of portable whole genome sequencing, molecular clock and epidemiological analyses, we revealed the return of the CHIKV-ECSA genotype into Bahia. …”
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Long-read sequencing revealed complex biallelic pentanucleotide repeat expansions in RFC1-related Parkinson’s disease by Peng Liu, Fan Zhang, Xinhui Chen, Xiaosheng Zheng, Miao Chen, Zhiru Lin, Shuqi Chen, Lebo Wang, Xinchen Wang, Nan Jin, Chenxin Ying, Fei Xie, Bo Wang, Sheng Wu, Zhidong Cen, Wei Luo

“…Long-read sequencing revealed a novel repeat configuration of (AGGGG)exp(AAGGG)14 and a possible somatic variant of (AAGGG)exp(AATGG)exp(AAGGG)exp in the (AAGGG)exp alleles in two RFC1-related PD patients. …”
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Aroma-Driven Differentiation of Wuyi Shuixian Tea Grades: The Pivotal Role of Linalool Revealed by OAV and Multivariate Analysis by Mengzhen Zhang, Ying Zhang, Yeyun Lin, Yuhua Wang, Jishuang Zou, Miaoen Qiu, Qingxu Zhang, Jianghua Ye, Xiaoli Jia, Haibin He, Haibin Wang, Qi Zhang

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High Bendability of Short RNA-DNA Hybrid Duplex Revealed by Single-Molecule Cyclization and Molecular Dynamics Simulations by Bin Wu, Fujia Tian, Yajun Yang, Liang Dai, Xinghua Zhang

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Characterization of TaMYB Transcription Factor Genes Revealed Possible Early-Stage Selection for Heat Tolerance in Wheat by Manu Maya Magar, Hui Liu, Guijun Yan

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Global Knowledge-Intensive Business Services Trade Flows. The Revealed Competitive Position of Europe and Central and Eastern Europe by Brodzicki Tomasz

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Transcriptome analysis revealed the molecular mechanism by which Chrysanthemum naktongense roots respond to low-concentration lanthanum treatment by Yaohui Gao, Ruiqing Zhang, Ning Xu, Ying Song, Shiao Chen, Miao He

“…The concentration analysis results of the top 20 KEGG pathways revealed that many of the upregulated DEGs that were significantly (p < 0.05) enriched were related to the plant hormone signal transduction pathway. …”
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Metabonomics and physiology revealed the critical function of 5-Phosphoribosylamine and antioxidant enzymes in enhancing aged oat seed germination by Yi Hua, Linling Dong, Shengnan Sun, Kexin Wang, Yilin Zou, Yongqi Gao, Ting Gong, Guofu Hu, Ligang Qin

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Long‐Term Landslide Evolution and Restoration After the Wenchuan Earthquake Revealed by Time‐Series Remote Sensing Images by Xin Wang, Xuanmei Fan, Chengyong Fang, Lanxin Dai, Wei Zhang, Hongrui Zheng, Qiang Xu

“…The restoration models were quantitatively established, revealing that the recoveries of post‐earthquake landslide activity and vital environmental indicators require a range from ∼5.29 to ∼25.00 years. …”
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Metagenomic Analysis Revealed the Changes in Antibiotic Resistance Genes and Heavy Metal Resistance Genes in Phosphate Tailings Compost by Chunqiao Xiao, Kai Wan, Yan Chen, Yongtong Jin, Fang Zhou, Junxia Yu, Ruan Chi

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Nitrogen and carbon isotopic relationships in the diet and eye lenses of chub mackerel revealed in a laboratory rearing experiment by Chisato Yoshikawa, Nanako O. Ogawa, Naoto F. Ishikawa, Michio Yoneda, Ryuji Yukami, Shin-ichi Ito, Naohiko Ohkouchi

“…The TDFs for N and C in the mackerel eye lenses were 2.8–3.4‰ and 2.1–2.6‰, respectively. A model simulation revealed that it requires 191 d for the eye lenses in fish that switched diets at 60 d of age to reach the observed TDF for N of 3.1‰, and that the eye lenses of the adults take longer to reach isotopic equilibrium than the eye lenses of actively growing juveniles. …”
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Visualization of Hg2+ Stress on Plant Health at the Subcellular Level Revealed by a Highly Sensitive Fluorescent Sensor by Sumeera Asghar, Zhenyang Yu, Zheng Zhu, Dengyue Zheng, Zimo Zhao, Yuming Xu, Xiao Liu, Chao Yuan, Yan Li, Wei Wang, Jianfeng Xu, Huailong Teng, Jun Li, Wen-Chao Yang, Chunli Chen

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Genetic diversity and population structure of 288 potato (Solanum tuberosum L.) germplasms revealed by SSR and AFLP markers by Jian WANG, Lu HOU, Ruo-yu WANG, Miao-miao HE, Qing-chang LIU

“…In general, the results obtained from Bayesian statistical analysis, cluster analysis and principal coordinate analysis consistently revealed the lack of geographical differentiation among country-wide collections, indicating germplasm introduction was common for the countries out of potato origin center. …”
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Architecture of Y-Family DNA Polymerases Relevant to Translesion DNA Synthesis as Revealed in Structural and Molecular Modeling Studies by Sushil Chandani, Christopher Jacobs, Edward L. Loechler

“…Y-Family DNAP architecture that dictates mechanism, as revealed in structural and modeling studies, is considered. …”
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Dynamic physiology and transcriptomics revealed the alleviation effect of melatonin on Reaumuria trigyna under continuous alkaline salt stress by Xuebo Li, Lei Wang, Heyi Wang, Rui Hao, Lunkai Gao, Hongbo Cui, Hai Wu, Xiaodong Wu, Tong Qiao, Weijie Bai, Liming Zhang

“…The key mechanism identified involves melatonin’s ability to increase antioxidant enzyme activity, reduce reactive oxygen species and hydrogen peroxide levels, and alter gene expression patterns.DiscussionTranscriptomic analysis revealed significant changes in gene expression, particularly in photosynthetic signal transduction, phytohormone signaling, MAPK signaling, and the peroxisome pathway, which are crucial for the plant’s response to alkaline salt stress. …”
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Genome-wide association study revealed candidate genes associated with leaf size in alfalfa (Medicago sativa L.) by Ming Xu, Yanchao Xu, Hao Liu, Qingsong Liu, Qingchuan Yang, Ruicai Long, Lin Chen, Fei He

“…Results Phenotypic analysis revealed varying degrees of variation among the four traits, with coefficients of variation ranging from 3.43 to 36.84%. …”
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Local recurrence of submucosal invasive colorectal cancer after endoscopic submucosal dissection revealed by copy number variation by Yu Okazawa, Kiichi Sugimoto, Yuki Ii, Takahiro Irie, Megumi Kawaguchi, Aya Kobari, Hirotaka Momose, Yuki Tsuchiya, Kota Amemiya, Shunsuke Motegi, Ryoichi Tsukamoto, Kazumasa Kure, Kumpei Honjo, Hisashi Ro, Rina Takahashi, Shingo Kawano, Masaya Kawai, Shun Ishiyama, Makoto Takahashi, Yutaka Kojima, Yuichi Tomiki, Atsushi Arakawa, Takashi Yao, Kaishi Satomi, Yuko Matsushita, Koichi Ichimura, Kazuhiro Sakamoto

“…Abstract We report a case in which analysis of copy number variation revealed local recurrence of submucosal invasive colorectal cancer after curative endoscopic submucosal dissection (ESD). …”
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