Transcriptome Profiles of the Liver in Two Cold-Exposed Sheep Breeds Revealed Different Mechanisms and Candidate Genes for Thermogenesis by Dan Jiao, Kaixi Ji, Wenqiang Wang, Hu Liu, Jianwei Zhou, A. Allan Degen, Yunsheng Zhang, Ping Zhou, Guo Yang

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A Human Engineered Heart Tissue‐Derived Lipotoxic Diabetic Cardiomyopathy Model Revealed Early Benefits of Empagliflozin by Lin Cai, Yuxin Zhao, Zilong Li, Liping Xiao, Yifan Wu, Shiya Wang, Qian Liu, Yida Ye, Yuxuan Guo, Donghui Zhang

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Metabolomics Revealed the Effects of <i>Momordica charantia</i> L. Saponins on Diabetic Hyperglycemia and Wound Healing in Mice by Dengdeng Zhao, Zixuan Luo, Shasha Li, Shuwen Liu, Chan Wang

“…Five potential biomarkers were screened in the metabolomics study. The results revealed that MCS mainly regulated glycerophospholipid metabolism, fructose and mannose metabolism, steroid hormone biosynthesis, pyrimidine metabolism, and the Krebs cycle, thus affecting wound healing. …”
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Watershed-scale dispersal patterns of juvenile Chinook Salmon (Oncorhynchus tshawytscha) revealed through genetic parentage analysis by Matthew J. Kaylor, Lindsy R. Ciepiela, Melody Feden, Joseph T. Lemanski, Casey Justice, Benjamin A. Staton, Jonathan B. Armstrong, Stefan Kelly, Shawn R. Narum, Ian A. Tattam, Seth M. White

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Spatiotemporal changes in riverine input into the Eocene North Sea revealed by strontium isotope and barium analysis of bivalve shells by Jorit F. Kniest, David Evans, Axel Gerdes, Marjorie Cantine, Jonathan A. Todd, Julia D. Sigwart, Johan Vellekoop, Wolfgang Müller, Silke Voigt, Jacek Raddatz

“…In particular, our results enable changes in riverine input along geological to perennial time scales for different coastal regions to be determined, revealing a steady influx of fresh water, but with distinct spatiotemporal differences.…”
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Multiple sex-associated regions and a putative sex chromosome in zebrafish revealed by RAD mapping and population genomics. by Jennifer L Anderson, Adriana Rodríguez Marí, Ingo Braasch, Angel Amores, Paul Hohenlohe, Peter Batzel, John H Postlethwait

“…The association of the end of chr-4 with sex is remarkable because, unique in the karyotype, this chromosome arm shares features with known sex chromosomes: it is highly heterochromatic, repetitive, late replicating, and has reduced recombination. Our results reveal that chr-4 has functional and structural properties expected of a sex chromosome.…”
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Near-Surface Stratigraphic Structure of the Regolith Revealed Using Chang'e-2 Microwave Brightness Temperature Data by Chen Zou, Guoping Hu, Wei Yang, Wuming Zhang

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Immunoglobulin A/PIGR axis as potential mediators of human abdominal aortic aneurysms revealed by topologically resolved proteomics by Isabel Cerro-Pardo, Estefanía Núñez, Belén Picatoste, Cristina Márquez-Gálvez, Lucía Ortega-Villanueva, Irene Raposo-Gutiérrez, Jes S. Lindholt, Luis Miguel Blanco-Colio, Almudena R. Ramiro, Jesús Vázquez, José Luis Martín-Ventura

“…Results Functional analysis of biological pathways altered in human AAA wall revealed a significant upregulation of components of the adaptive immune response, including IGHA1 and IGHA2, as well as the IGA receptor, PIGR. …”
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Longitudinal analysis of the antibody repertoire of a Zika virus-infected patient revealed dynamic changes in antibody response by Xuefeng Niu, Qihong Yan, Zhipeng Yao, Fan Zhang, Linbing Qu, Chunlin Wang, Chengrui Wang, Hui Lei, Chaoming Chen, Renshan Liang, Jia Luo, Qian Wang, Lingzhai Zhao, Yudi Zhang, Kun Luo, Longyu Wang, Hongkai Wu, Tingting Liu, Pingchao Li, Zhiqiang Zheng, Yee Joo Tan, Liqiang Feng, Zhenhai Zhang, Jian Han, Fuchun Zhang, Ling Chen

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16S rRNA and transcriptome analysis revealed the regulatory mechanism of Romboutsia lituseburensis on serum immunoglobulin levels in geese by Zhiyu He, Mengge Guo, Xi Zhang, Shangmin Wang, Tanze Liu, Yueyue Lin, Qingyuan Ouyang, Shenqiang Hu, Hua He, Liang Li, Hehe Liu, Jiwen Wang

“…Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis revealed that these DEGs were enriched in 17 pathways in the ileum and 21 pathways in the spleen. …”
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The cypriot blunt-nosed viper Macrovipera lebetinus lebetinus: complete mitochondrial genome revealed by next-generation sequencing by Stephan Siegert, Joel Fonseca Nogueira, Daniel Jestrzemski, Mike Reich, Bertram Brenig

“…Comparative analysis reveals a conserved gene order typical for Viperidae but also an unprecedented structural modification: the complete loss of the D-arm in tRNA-Cys, a feature previously unreported in snakes. …”
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Grapevine virus T diversity as revealed by full-length genome sequences assembled from high-throughput sequence data. by Shaheen Nourinejhad Zarghani, Jean Michel Hily, Miroslav Glasa, Armelle Marais, Thierry Wetzel, Chantal Faure, Emmanuelle Vigne, Amandine Velt, Olivier Lemaire, Jean Michel Boursiquot, Arnela Okic, Ana Belén Ruiz-Garcia, Antonio Olmos, Thierry Lacombe, Thierry Candresse

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Differential neuronal functions of LNX1 and LNX2 revealed by behavioural analysis in single and double knockout mice by Laura Cioccarelli, Joan A. Lenihan, Leah G. Erwin, Paul W. Young

“…Analysis of the ultrasonic vocalizations of pups following maternal separation revealed significant differences in call properties and vocal repertoire for Lnx1 -/- and Lnx1 -/- ;Lnx2 -/- double knockout animals. …”
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Research hotspots and trends in lung cancer immunotherapy are revealed by a bibliometric study spanning the years 2004 to 2024 by Xu Sun, Hongxia Cheng, Jing Zhao, Zhihui Jia, Qiong Xu

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Mg2+-Ion Dependence Revealed for a BAHD 13‑O‑β-Aminoacyltransferase from Taxus Plants by Aimen Al-Hilfi, Zhen Li, Kenneth M. Merz, Kevin D. Walker

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Planetary Wave Activity During 2019 Sudden Stratospheric Warming Event Revealed by ERA5 Reanalysis Data by Yushun Yang, Haiyan Li

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A dataset of hidden small non-coding RNA in the testis of heat-stressed models revealed by Pandora-seq by Mailin Gan, Yuhang Lei, Kai Wang, Yan Wang, Tianci Liao, Jianfeng Ma, Li Zhu, Linyuan Shen

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Gene regulatory activity associated with polycystic ovary syndrome revealed DENND1A-dependent testosterone production by Laavanya Sankaranarayanan, Kelly J. Brewer, Shauna Morrow, Graham D. Johnson, Alejandro Barrera, Revathy Venukuttan, Ryan Sisk, Andrea Dunaif, Timothy E. Reddy

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Reinstatement of the genus Psorodendron and related systematic novelties as revealed from phylogenetic analyses of the tribe Amorpheae (Leguminosae, Papilionoideae) by Paola Piñeros Urrego, Harold Suárez-Barón, Natalia Pabón-Mora, Favio González

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Immune-related gene characterization and biological mechanisms in major depressive disorder revealed based on transcriptomics and network pharmacology by Shasha Wu, Shasha Wu, Qing Jiang, Jinhui Wang, Jinhui Wang, Daming Wu, Yan Ren

“…Immune infiltration analysis revealed significant correlations between immune cells, including Mast cells resting, T cells CD8, NK cells resting, and Neutrophils, which were significantly correlated with the hub genes expression. …”
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