Whole-genome survey reveals the genomic characteristics and phylogeny of three species within the family Echeneidae by Fenglin Wang, Fenglin Wang, Qi Liu, Yinquan Qu, Tianxiang Gao, Xingle Guo, Xiumei Zhang

“…The results of the PSMC analysis revealed that these three species experienced rapid population expansion before the Last Interglacial Period, followed by a decline in their populations after reaching their peak during the Last Glacial Period. …”
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Integrated lipidomics and RNA-seq reveal prognostic biomarkers in well-differentiated and dedifferentiated retroperitoneal liposarcoma by Xiaopeng Wang, Jingjing Ye, Yan Wu, Hongtao Zhang, Chengpeng Li, Bonan Liu, Xiaoya Guan, Xiuyun Tian, Weiwei Jia, Qiao Liu, Shuquan Li, Rongze Sun, Daoning Liu, Guoqiang Xue, Zhen Wang, Liang Yan, Ang Lv, Jianhui Wu, Hui Qiu, Chunyi Hao

“…Results Lipidomic analysis revealed a significant difference in lipid metabolism, particularly in phosphatidylcholines and triacylglycerides metabolism. …”
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A telomere-associated molecular landscape reveals immunological, microbial, and therapeutic heterogeneity in colorectal cancer by Yinmeng Zhang, Jiawei Fan, Jiahui Zhao, He Zhu, Yan Xia, Hong Xu

“…This was reflected by elevated ESTIMATE/TIDE scores and corroborated by CIBERSORT, which revealed increased infiltration of M0 macrophages and upregulation of immunosuppressive signatures. …”
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Integrated Analysis of DNA Methylome and Transcriptome Reveals Regulatory Mechanism in the Longissimus Dorsi of Duroc Pigs by Shiyin Li, Yarui Gao, Lixia Ma, Wei Chen, Zhao Ma, Zhanchi Ren, Yunzhou Wang, Yongqing Zeng

“…In this study, we analyzed the DNA methylome and transcriptome of the longissimus dorsi muscle (LDM) in Duroc pigs with varying growth rates. Our results reveal that DNA methylation suppressed the expression of key muscle development markers (<i>MYOD</i>, <i>MYOG</i>, <i>MHC1</i>) and proliferation markers (<i>PI67</i>, <i>PCNA</i>), as well as the protein expression and phosphorylation of PI3K and AKT (<i>p</i> < 0.05). …”
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Genome wide analyses reveal the role of mutator phenotypes in Mycobacterium tuberculosis drug resistance emergence by R. Zein-Eddine, A. Le Meur, S. Skouloubris, L. Jelsbak, G. Refrégier, H. Myllykallio

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Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. by Chenxing Liu, Myoung Keun Lee, Sahin Naqvi, Hanne Hoskens, Dongjing Liu, Julie D White, Karlijne Indencleef, Harold Matthews, Ryan J Eller, Jiarui Li, Jaaved Mohammed, Tomek Swigut, Stephen Richmond, Mange Manyama, Benedikt Hallgrímsson, Richard A Spritz, Eleanor Feingold, Mary L Marazita, Joanna Wysocka, Susan Walsh, Mark D Shriver, Peter Claes, Seth M Weinberg, John R Shaffer

“…Previous genome scans have revealed more than 100 genetic loci associated with different aspects of normal-range facial variation. …”
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Tn-seq profiling reveals that NodS of the beta-rhizobium Paraburkholderia phymatum is detrimental for nodulating soybean by Paula Bellés-Sancho, Daphné Golaz, Sarah Paszti, Alessandra Vitale, Yilei Liu, Aurélien Bailly, Leo Eberl, Euan K. James, Gabriella Pessi

“…Moreover, infection tests with different host plants reveal that NodS is necessary for optimal nodulation of common bean (Phaseolus vulgaris), but it is not required for nodulation of its natural host Mimosa pudica. …”
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Retraction: Revealing the effects of corporate governance on green investment and innovation: do law and policy matter? by Frontiers Editorial Office

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An atlas of RNA-dependent proteins in cell division reveals the riboregulation of mitotic protein-protein interactions by Varshni Rajagopal, Jeanette Seiler, Isha Nasa, Simona Cantarella, Jana Theiss, Franziska Herget, Bianca Kaifer, Melina Klostermann, Rainer Will, Martin Schneider, Dominic Helm, Julian König, Kathi Zarnack, Sven Diederichs, Arminja N. Kettenbach, Maïwen Caudron-Herger

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Single-nucleus RNA sequencing reveals a preclinical model for the most common subtype of glioblastoma by Laura García-Vicente, María Martínez-Fernández, Michael Borja, Vanessa Tran, Andrea Álvarez-Vázquez, Raquel Flores-Hernández, Yuxin Ding, Raúl González-Sánchez, Alejandro Granados, Erin McGeever, Yang-Joon Kim, Angela Detweiler, Honey Mekonen, Sheryl Paul, Angela O. Pisco, Norma F. Neff, Arantxa Tabernero

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URBAN AND PERI-URBAN AGRICULTURE IN BRAZILIAN CAPITALS: WHAT DOES RECENT ACADEMIC PRODUCTION REVEAL? by Eugenia Aumond Kuhn, Geisa Zanini Rorato, Bruno Cesar Euphrasio de Mello, Carolina Cristófoli Falcão, Rodrigo Vitória Alves

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Spatial heterogeneity reveals an evolutionary signature predicting therapeutic response and clinical outcomes in hepatocellular carcinoma by Shangyi Luo, Li Liu, Yang Sun, Jian Shi, Yajing Zhang, Yajing Zhang, Yajing Zhang

“…Additionally, we established a well-calibrated predictive nomogram that integrates HCCEvoSig and TNM stage to generate an individualized numerical probability of mortality.ConclusionOur study reveals that regional transcriptional heterogeneity within tumors is substantial enough to capture survival signals, and the constructed and validated HCCEvoSig provides reliable prognostic information for HCC patients.…”
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An integrated physiological indicator and transcriptomic analysis reveals the response of soybean buds to high-temperature stress by Jiajia Li, Meiyan Wu, Haoran Chen, Wei Liao, Shu Yao, Ying Wei, Heng Wang, Qun Long, Xiaoyu Hu, Wei Wang, Guoji Wang, Lijuan Qiu, Xiaobo Wang

“…Bioinformatic analysis revealed that most DEGs were mainly involved in metabolic processes, catalytic activity, carbohydrate, energy transduction, and signaling pathways. …”
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Sulfur isotopes from the lunar farside reveal global volatile loss following the giant impact by Yiheng Li, Zaicong Wang, Wen Zhang, Keqing Zong, Zhenbing She, Qi He, Jiaqi Zheng, Tianyang Li, Fabin Pan, Xu Chen, Kosta Crnobrnja, Long Xiao, Zhaochu Hu, Xiang Wu, Yongsheng Liu, Julien Siebert, Frédéric Moynier

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Rare ice-base temperature measurements in Antarctica reveal a cold base in contrast with predictions by Pavel G. Talalay, German Leitchenkov, Vladimir Lipenkov, Youhong Sun, Nan Zhang, Da Gong, Yunchen Liu, Yazhou Li, Yuchen Sun, Ilnur Abdrakhmanov, Mstislav Vorobyev, Damir Khalimov, Xiaopeng Fan, Andrey Salamatin, Alexey A. Ekaykin, Bing Li

“…Temperature measurements at the bottom of the borehole revealed a cold underlying base despite a warm-based interface being predicted in advance as the most likely estimate. …”
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Transcriptome analysis of archived tumors by Visium, GeoMx DSP, and Chromium reveals patient heterogeneity by Yixing Dong, Chiara Saglietti, Quentin Bayard, Almudena Espin Perez, Sabrina Carpentier, Daria Buszta, Stephanie Tissot, Rémy Dubois, Atanas Kamburov, Senbai Kang, Carla Haignere, Rita Sarkis, Sylvie Andre, Marina Alexandre Gaveta, Silvia Lopez Lastra, Nathalie Piazzon, Rita Santos, Katharina von Loga, Caroline Hoffmann, George Coukos, Solange Peters, Vassili Soumelis, Eric Yves Durand, Laurence de Leval, Raphael Gottardo, Krisztian Homicsko, Elo Madissoon

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Choroid plexus organoids reveal mechanisms of Streptococcus suis translocation at the blood-cerebrospinal fluid barrier by Tiantong Zhao, Laura Pellegrini, Bart van der Hee, Jos Boekhorst, Aline Fernandes, Sylvia Brugman, Peter van Baarlen, Jerry M. Wells

“…Here, we used human induced pluripotent stem cells (iPSC)-derived ChP organoids as an in vitro model to investigate S. suis interaction and infection at the BCSFB. Our study revealed that S. suis is capable of translocating across the epithelium of ChP organoids without causing significant cell death or compromising the barrier integrity. …”
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Multi-platform omics analysis of Nipah virus infection reveals viral glycoprotein modulation of mitochondria by Gunner P. Johnston, Fikret Aydemir, Haewon Byun, Emmie de Wit, Kristie L. Oxford, Jennifer E. Kyle, Jason E. McDermott, Brooke L. Deatherage Kaiser, Cameron P. Casey, Karl K. Weitz, Heather M. Olson, Kelly G. Stratton, Natalie C. Heller, Viraj Upadhye, I. Abrrey Monreal, J. Lizbeth Reyes Zamora, Lei Wu, D.H. Goodall, David W. Buchholz, Joeva J. Barrow, Katrina M. Waters, Ruth N. Collins, Heinz Feldmann, Joshua N. Adkins, Hector C. Aguilar

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Single‐Cell Transcriptome Reveals Aquaporin‐Mediated Carbon Nanosol‐Induced Growth Promotion of Plants by Lingtong Cheng, Zechao Qu, Qiansi Chen, Lin Wang, Huan Su, Jiemeng Tao, Peng Lu, Taibo Liang, Jianfeng Zhang, Peijian Cao, Jingjing Jin

“…Track of fluorescent labeling CNS reveals that it is rapidly absorbed by roots and entered the vascular bundle and cortex within 2 h. …”
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Crossing borders: Connectivity analyses reveal potential patterns of range expansion of the Northern raccoon in Europe by Mattia Falaschi, Andrea Simoncini, Leonardo Ancillotto, Andrea Viviano, Mattia Menchetti, Giuseppe Mazza, Emiliano Mori

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