Single-cell transcriptomic analysis reveals metastatic and immunosuppressive characteristics in meningioma brain-tumor interface by Boya Huang, Jinlian Liang, Xiaogen Tang, Yue Zhu, Lijuan Gao, Dongwei Fu, Cheng Wei, Yifang Li, Chao Ke, Hongyi Zhang, Oscar Junhong Luo

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Integrative network analysis reveals novel moderators of Aβ-Tau interaction in Alzheimer's disease by Akihiro Kitani, Yusuke Matsui, for the Alzheimer’s Disease Neuroimaging Initiative

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Whole‐brain microscopy reveals distinct temporal and spatial efficacy of anti‐Aβ therapies by Daniel Kirschenbaum, Ehsan Dadgar‐Kiani, Francesca Catto, Fabian F Voigt, Chiara Trevisan, Oliver Bichsel, Hamid Shirani, K Peter R Nilsson, Karl J Frontzek, Paolo Paganetti, Fritjof Helmchen, Jin Hyung Lee, Adriano Aguzzi

“…Furthermore, aligning with a spatial‐transcriptomic atlas revealed transcripts that correlate with the efficacy of each Aβ therapy. …”
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Shigella sonnei infection of zebrafish reveals that O-antigen mediates neutrophil tolerance and dysentery incidence. by Vincenzo Torraca, Myrsini Kaforou, Jayne Watson, Gina M Duggan, Hazel Guerrero-Gutierrez, Sina Krokowski, Michael Hollinshead, Thomas B Clarke, Rafal J Mostowy, Gillian S Tomlinson, Vanessa Sancho-Shimizu, Abigail Clements, Serge Mostowy

“…Collectively, these findings reveal O-antigen as an important therapeutic target against bacillary dysentery, and may explain the rapidly increasing S. sonnei burden in developing countries.…”
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Integrated analysis and experimental validation reveal the prognostic and immunological features associated with coagulation in hepatocellular carcinoma by Guangzhen Qu, Kun Liu, Weiyu Xu, Dongming Li

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Phosphoproteome Reveals the Role of Baicalin in Alleviating rPVL-Induced Cell Cycle Arrest in BMECs by Ling Hou, Jun Li, Juqing Wang, Qin You, Dongtao Zhang, Xuezhang Zhou

“…Quantitative immunohistochemical analysis revealed that baicalin mitigated the rPVL-induced dephosphorylation of the aforementioned cell-cycle-related proteins and increased their phosphorylation. …”
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Acoustic Monitoring of Oxygen Ebullition Reveals Hidden Productivity in a Seemingly Heterotrophic Seagrass Meadow by Kyle A. Capistrant-Fossa, Megan S. Ballard, Kevin M. Lee, Colby W. Cushing, Andrew R. McNeese, Thomas S. Jerome, Preston S. Wilson, Kenneth H. Dunton

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Neural Network-Aided NILM (NNAN) disaggregation: Revealing appliance consumption patterns with iterative subtraction by Yacine Belguermi, Patrice Wira, Gilles Hermann

“…This article introduces a novel approach which is a Neural Network-Aided NILM (NNAN), focusing on revealing appliance consumption patterns by following a sequential subtraction method. …”
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Transcriptomic profiling of blood from autoimmune hepatitis patients reveals potential mechanisms with implications for management. by Michele May-Sien Tana, Arielle Klepper, Amy Lyden, Angela Oliveira Pisco, Maira Phelps, Breann McGee, Kelsey Green, Sandy Feng, Joseph DeRisi, Emily Dawn Crawford, Craig S Lammert

“…Differential gene expression analysis revealed 249 genes that were significantly differentially expressed in AIH patients compared to controls. …”
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Robust substrate profiling method reveals striking differences in specificities of serum and lung fluid proteases by Douglas S. Watson, Kalyani Jambunathan, David S. Askew, Krishna Kodukula, Amit K. Galande

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Bioengineered 3D microvessels and complementary animal models reveal mechanisms of Trypanosoma congolense sequestration by Teresa Porqueddu, Maria Zorrinho-Almeida, Mariana De Niz, Aitor Casas-Sánchez, Viola Introini, Silvia Sanz Sender, Diana Carrasqueira, Luísa M. Figueiredo, Maria Bernabeu, Sara Silva Pereira

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Extreme signal amplitude events in neuromagnetic oscillations reveal brain aging processing across adulthood by Vasily A. Vakorin, Vasily A. Vakorin, Hayyan Liaqat, Sam M. Doesburg, Sylvain Moreno

“…We characterized extreme neurodynamics by computing sample skewness and kurtosis, and used Partial Least Squares to test for differences across age groups.ResultsOur findings revealed that each canonical frequency, from theta to lower gamma, displayed unique spatial patterns of either age-related increases, decreases, or both in the brain’s tendency to produce extreme neuromagnetic events.DiscussionOur study introduces a novel neuroimaging framework for understanding ageing through the extreme and rare events of the neurophysiological activity, offering more sensitivity than typical comparative approaches.…”
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Time-course transcriptomic information reveals the mechanisms of improved drought tolerance by drought priming in wheat by Qing Li, Zhuangzhuang Sun, Zihan Jing, Xiao Wang, Chuan Zhong, Wenliang Wan, Maguje Masa Malko, Linfeng Xu, Zhaofeng Li, Qin Zhou, Jian Cai, Yingxin Zhong, Mei Huang, Dong Jiang

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Metabolic Profiling Reveals Potential Prognostic Biomarkers for SFTS: Insights into Disease Severity and Clinical Outcomes by Zhuo-Min Zhu, Huan-Yu Liu, Na An, An-Ling Li, Jia Li, Sai-Jun Wang, Gui Yang, Yong-Wei Duan, Ying Yang, Mei Zhang, Quan-Fei Zhu, Song-Mei Liu, Yu-Qi Feng

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The power of microsatellite markers and AFLPs in revealing the genetic diversity of Hashemi aromatic rice from Iran by Alireza Tarang, Anahita Bakhshizadeh Gashti

“…Later, a unweighted pair group method with arithmetic mean (UPGMA) dendrogram was generated and genotypes were clustered into four groups with SSRs at similarity coefficient of 0.55 while AFLPs clustered them into six groups at similarity coefficient of 0.41. Cluster analysis revealed a narrow genetic diversity and low correlation between geographical differentiation and genetic distance within cultivars.…”
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Autografted vines of cultivar ‘Refošk’ (Vitis vinifera L.) reveal symptoms of the rugose wood disease by Matjaž HLADNIK, Dunja BANDELJ, Irma VUK

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Metabolite and Transcriptomic Changes Reveal the Cold Stratification Process in <i>Sinopodophyllum hexandrum</i> Seeds by Rongchun Ning, Caixia Li, Tingting Fan, Tingting Ji, Wenhua Xu

“…To investigate the biosynthetic and conversion processes of plant hormones related to seed dormancy and germination, the transcriptome of <i>S. hexandrum</i> seeds was monitored via RNA-seq, revealing 65,372 differentially expressed genes associated with plant hormone synthesis and signaling. …”
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Integrative analysis of T cell-associated markers in Ewing sarcoma reveals prognostic signatures and immune dynamics by Umair Ali Khan Saddozai, Umair Ali Khan Saddozai, Chenxu Liu, Chenxu Liu, Fei Yan, Zhendong Lu, Muhammad Babar Khawar, Muhammad Babar Khawar, Muhammad Usman Akbar, Saadullah Khattak, Haibo Sun, Haibo Sun, Ping Yang

“…Immune infiltration was assessed using the CIBERSORT algorithm.ResultsT cell marker analyses revealed key roles in pathways such as PI3K-Akt signaling and immune modulation. …”
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A multi-omic meta-analysis reveals novel mechanisms of insecticide resistance in malaria vectors by Sanjay C. Nagi, Victoria A. Ingham

“…Gene expression clusters physically in the genome, revealing potential coordinated regulation, and we find that highly over-expressed genes are associated with selective sweep loci. …”
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Untargeted metabolomics reveals key pathways in miscarriage: steroid, folate, fatty acid & glycosaminoglycan metabolism by Chee Wai Ku, Yu Bin Tan, Kuan Yang Chew, Chee Onn Ku, Shi Tong Carissa Ng, Thiam Chye Tan, Yie Hou Lee

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