Revealing the Neural Basis of Muscle Synergies in Humans through Direct Electrical Stimulation of the Motor Cortex by Jodie J. Xie, Subing Huang, Kelvin Lau, Amy HS. Kong, Rosa H.M. Chan, Peter Y.M. Woo, Vincent C.K. Cheung

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Comparative metabolomics reveal the biochemical basis of mulberry fruit decay during low temperature storage by Feng Zhang, Ting Zhai, Zhixian Zhu, Zhaoxia Dong, Cheng Zhang, Cui Yu

“…Furthermore, exogenous fatty acid effectively inhibits mulberry fruit decay during 4 °C storage and the lipid-soluble extract from mulberry fruits has strong antibacterial activity. These findings reveal that lipids are involved in mulberry fruit decay, and provide novel insights into the biochemical underpinnings of mulberry fruit decay of postharvest.…”
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Ten new species of Leucoagaricus and Leucocoprinus from Beijing: Revealing rich diversity in temperate regions by Jia-Xin Li, Bin Cao, Mao-Qiang He, Xin-Yu Zhu, Dong-Mei Liu, Rui-Lin Zhao

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Functionally enriched epigenetic clocks reveal tissue-specific discordant aging patterns in individuals with cancer by Chiara M. S. Herzog, Elisa Redl, James Barrett, Sepideh Aminzadeh-Gohari, Daniela D. Weber, Julia Tevini, Roland Lang, Barbara Kofler, Martin Widschwendter

“…Surprisingly, both mouse and human data reveal accelerated aging in breast cancer tissue but decelerated epigenetic aging in some non-cancer surrogate samples from breast cancer patients, in particular cervical samples. …”
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Footprint-C reveals transcription factor modes in local clusters and long-range chromatin interactions by Xiaokun Liu, Hanhan Wei, Qifan Zhang, Na Zhang, Qingqing Wu, Chenhuan Xu

“…When analyzed at one-dimensional level, the billions of chromatin contacts from Footprint-C enable genome-wide analysis at single footprint resolution, and reveal preferential modes of local TF co-occupancy. …”
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METHODS OF REVEALING OF DISCONTINUITY FLAWS AND CONTROL OF THE CAST IRONS STRUCTURE USING BODY AND HEAD WAVES by A. R. Bajev, G. E. Konovalov, A. L. Majorov, M. V. Asadchaja, M. A. Tishchenko

“…The results of investigation of influence of graphite form on speed of ultrasound are given and also some peculiarities the surface und subsurface faults reveal by shadow way.…”
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Metabolomic Profiling Reveals That Exercise Lowers Biomarkers of Cardiac Dysfunction in Rats with Type 2 Diabetes by Tutu Wang, Miaomiao Ning, Yurou Mo, Xinyu Tian, Yu Fu, Ismail Laher, Shunchang Li

“…This study utilizes untargeted metabolomics to reveal aerobic-exercise-activated metabolic biomarkers in the cardiac tissues of Sprague Dawley rats with T2DM. …”
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Chimerism in specimens referred to Saurophaganax maximus reveals a new species of Allosaurus (Dinosauria, Theropoda) by Andrew Danison, Mathew Wedel, Daniel Barta, Holly Woodward, Holley Flora, Andrew Lee, Eric Snively

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Integrative Multi-Omics Profiling of Rhabdomyosarcoma Subtypes Reveals Distinct Molecular Pathways and Biomarker Signatures by Aya Osama, Ahmed Karam, Abdelrahman Atef, Menna Arafat, Rahma W. Afifi, Maha Mokhtar, Taghreed Khaled Abdelmoneim, Asmaa Ramzy, Enas El Nadi, Asmaa Salama, Emad Elzayat, Sameh Magdeldin

“…Differential expression, functional enrichment (GO, KEGG, RaMP-DB), co-expression network analysis (WGCNA/WMCNA), and multi-omics integration (DIABLO, MOFA) revealed distinct molecular signatures for each subtype. …”
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Machine learning reveals distinct aquatic organic matter patterns driven by soil erosion types by Yingxin Shang, Kaishan Song, Zhidan Wen, Fengfa Lai, Ge Liu, Hui Tao, Xiangfei Yu

“…We then applied this model to map the spatial distribution of CDOM across lakes larger than 0.1 km2 in 2020. Our analysis revealed distinct spatial patterns, with mean CDOM absorption coefficients at 355 nm of 3.73 m-1 in freeze-thaw erosion regions, 6.31 m-1 in wind erosion regions, and 3.72 m-1 in hydraulic erosion regions, reflecting significant variations driven by erosion intensity. …”
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Genomic analysis of the early COVID-19 pandemic in Haiti reveals Caribbean-specific variant dynamics. by Alexandra Mushegian, Allie Kreitman, Martha I Nelson, Matthew Chung, Christopher Mederos, Allison Roder, Stephanie Banakis, Anne Marie Desormeaux, Nadia Lapierre Jean Charles, Yoran Grant-Greene, Samson Marseille, Katilla Pierre, Donald Lafontant, Jacques Boncy, Ito Journel, Josiane Buteau, Stanley Juin, Elodie Ghedin

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Integrated transcriptomics and epigenomics reveal chamber-specific and species-specific characteristics of human and mouse hearts. by Junpeng Gao, Yuxuan Zheng, Lin Li, Minjie Lu, Xiangjian Chen, Yu Wang, Yanna Li, Xiaomeng Liu, Yun Gao, Yunuo Mao, Peng Zhao, Jinan Zhang, Fuchou Tang, Lei Song, Lu Wen, Jizheng Wang

“…Furthermore, cross-species comparisons revealed human-specific and mouse-specific differentially expressed genes between the atria and ventricles. …”
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Temporal single-cell sequencing analysis reveals that GPNMB-expressing macrophages potentiate muscle regeneration by Yu-Fan Chen, Chien-Wei Lee, Yi-Shuan J. Li, Wei-Ting Lin, Hsiao-Yun Chen, Yu-Chuan Chen, Chia-Hao Lin, Jennifer Hui-Chun Ho, Li-Fan Lu, Shu Chien, Oscar Kuang-Sheng Lee

“…Here, to address this issue, we induced injury and performed single-cell RNA sequencing on individual cells in skeletal muscle at different time points. Our analysis revealed a distinct macrophage subset that expressed high levels of Gpnmb and that coexpressed critical factors involved in macrophage-mediated muscle regeneration, including Igf1, Mertk and Nr1h3. …”
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Proteomics reveals the key transcription-related factors mediating obstructive nephropathy in pediatric patients and mice by Hualin Cao, Yuandong Tao, Ruyue Jin, Pin Li, Huixia Zhou, Jiwen Cheng

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Integrated analysis of blood microbiome and metabolites reveals key biomarkers and functional pathways in myocardial infarction by Ikram Khan, Stefan Panaiotov, Kotb A. Attia, Arif Ahmed Mohammed, Muhammad Uzair, Imran Khan, Zhiqiang Li, Xiaodong Xie

“…Functional pathway analysis revealed upregulation in glycerolipid metabolism and mTOR signaling pathways, which were significantly correlated with clinical markers of MI. …”
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Fecal profiling reveals a common microbial signature for pancreatic cancer in Finnish and Iranian cohorts by Heidelinde Sammallahti, Sama Rezasoltani, Satu Pekkala, Arto Kokkola, Hamid Asadzadeh Agdaei, Mehdi Azizmohammad Looha, Reza Ghanbari, Farhad Zamani, Amir Sadeghi, Virinder Kaur Sarhadi, Marja Tiirola, Pauli Puolakkainen, Sakari Knuutila

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Phosphoproteomic analyses reveal novel cross‐modulation mechanisms between two signaling pathways in yeast by Stefania Vaga, Marti Bernardo‐Faura, Thomas Cokelaer, Alessio Maiolica, Christopher A Barnes, Ludovic C Gillet, Björn Hegemann, Frank van Drogen, Hoda Sharifian, Edda Klipp, Matthias Peter, Julio Saez‐Rodriguez, Ruedi Aebersold

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Co-profiling of translatome and transcriptome reveals the regulation of dynamic gene expression during Drosophila embryogenesis by Zhang Le, Liu Qiufang, Liu Yulong, Ye Bishan, Hu Chuansheng, Li Xinhui, Bai Ling, Cheng Ming, Zhao Mingzhu, Li Hongmei, Li Hua

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Genome assembly and population analysis of tetraploid marama bean reveal two distinct genome types by Jin Li, Christopher Cullis

“…Whole-genome duplication (WGD) analysis revealed an ancient duplication event in marama. Gene family analysis revealed expanded families enriched in pathways related to stress adaptation, energy metabolism, and environmental signaling, including the spliceosome, citrate cycle, and carbon fixation pathways. …”
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Genome-wide association studies on longitudinal phenotypes reveal genetic mechanisms of egg production in chickens by Lizhi Tan, Ning Xu, Zexuan Liu, Xinyu Cai, Yuan Kong, Zilong Wen, Yuzhan Wang, Yiqiang Zhao

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