Revealing the underlying mechanisms of nanoplastics induces neuroinflammation: From transcriptomic analysis to in vivo and in vitro validation by Xiaomei Lu, Qinghua Luo, Jiahao Zhao, Ming Li, Dandan Liu

“…Therefore, this study aims to reveal the underlying mechanisms of NPs-induced neurotoxicity. …”
Get full text

Unseen crisis: Revealing the hidden health impact of indoor air pollution—A scoping review by Ranjana G. Chavan, Jasneet Kaur, Gopal S. Charan

“…The synthesis of findings from the selected studies reveals the multifaceted impact of indoor air pollution on health status. …”
Get full text

Machine Learning Reveals the Seismic Signature of Eruptive Behavior at Piton de la Fournaise Volcano by C. X. Ren, A. Peltier, V. Ferrazzini, B. Rouet‐Leduc, P. A. Johnson, F. Brenguier

Get full text

Single-cell transcriptomics reveals novel chondrocyte and osteoblast subtypes and their role in knee osteoarthritis pathogenesis by Yuan Liu, Wacili Da, Ming-Jie Xu, Chao-Xin Xiao, Tao Deng, Sheng-Liang Zhou, Xiao-Ting Chen, Yao-Jia Zhou, Li Tang, Yong Nie, Yi Zeng, Hui-Qi Xie, Bin Shen

Get full text

Resting-State Functional MRI Reveals Altered Seed-Based Connectivity in Diabetic Osteoporosis Patients by Li J, Liu M, Qin J, An Y, Zheng X, Mohamad NS, Ramli I

“…The seed regions for functional connectivity (FC) analysis were chosen according to brain areas previously reported to exhibit abnormal regional homogeneity (ReHo).Results: DOP patients exhibited significantly decreased BMD, T-scores, MoCA scores, and osteocalcin (OC) levels compared to controls (p< 0.05). FC analysis revealed: 1) Reduced connectivity between the left middle temporal gyrus (increased ReHo) and middle occipital gyrus; 2) Enhanced connectivity between the right angular gyrus (increased ReHo) and left Rolandic operculum; 3) Weakened the left precuneus (increased ReHo) and right superior/left middle frontal gyri. …”
Get full text

A Drosophila model of Pontocerebellar Hypoplasia reveals a critical role for the RNA exosome in neurons. by Derrick J Morton, Binta Jalloh, Lily Kim, Isaac Kremsky, Rishi J Nair, Khuong B Nguyen, J Christopher Rounds, Maria C Sterrett, Brianna Brown, Thalia Le, Maya C Karkare, Kathryn D McGaughey, Shaoyi Sheng, Sara W Leung, Milo B Fasken, Kenneth H Moberg, Anita H Corbett

“…RNA-seq analysis of these Drosophila Rrp40 mutants reveals increases in the steady-state levels of specific mRNAs and ncRNAs, some of which are central to neuronal function. …”
Get full text

Mendelian randomization study of lipid metabolites reveals causal associations with age-related macular degeneration by Miao Shui, Guoke Yang, Jiang Jiang, Sibo Wang, Rongfeng Liao

“…Results: IVW analysis revealed significant associations between several lipid metabolites and AMD. …”
Get full text

Proteomics analysis reveals the mechanism of anemoside B4 in treating clinical mastitis in dairy cows by Zeru Zhang, Yuquan Zhao, Zhetong Su, Ke Dong, Zhicai Zuo, Yixin Huang, Shumin Yu, Suizhong Cao, Liuhong Shen

“…This study was based on Label free relative quantitative proteomics technology to reveal the internal mechanism of AB4 treatment of CM; (2) Methods: Twelve healthy Chinese Holstein cows (group C) and twelve Chinese Holstein cows (group T) with CM were selected. …”
Get full text

Correction: Paired proteomic analysis reveals protein alterations in sun-exposed skin of professional drivers by Amanda C. Camillo-Andrade, Lucas A. Sales, Juliana S. G. Fischer, Rosario Duran, Marlon D. M. Santos, Paulo C. Carvalho

Get full text

A Vascularized Multilayer Chip Reveals Shear Stress-Induced Angiogenesis in Diverse Fluid Conditions by Tao Yue, Huiying Yang, Yue Wang, Ning Jiang, Hongze Yin, Xiaoqi Lu, Na Liu, Yichun Xu

Get full text

Revealing the impact of teaching methods on anxiety among college students through a bibliometric study by Zhongzhu Ai, Dongfeng Yuan, Ruotong Dong, Yun Li, Shanshan Zhou

“…Data-driven analysis was conducted to explore collaboration patterns, knowledge structures, research hotspots, and trends using VOSviewer software.ResultsAfter screening, this study included 192 publications from January 2004 to November 2024, revealing several significant findings: (1) The number of publications has gradually increased, peaking in 2022 and maintaining a high level in the following years. (2) The most productive and influential journals are Nurse Education Today and CBE Life Sciences Education, with the USA and the Indiana University System contributing the most. (3) Collaboration network analysis indicates the presence of multiple research groups in the field, but their connections among countries and authors remain relatively limited. (4) Co-citation analysis of journals shows that the field is interdisciplinary, primarily merging psychology, education, and information technology. (5) Keyword analysis identifies two major research hotspots: factors influencing student anxiety in teaching environments (e.g., self-efficacy, loneliness, and performance) and the moderating effects of teaching method reforms (e.g., blended learning, collaborative learning, and experiential learning) on college student anxiety.ConclusionThis visualization analysis provides an overview of the directions and advancements in research on the impact of teaching method reforms on college students' anxiety. …”
Get full text

Comparative acetylome analysis reveals the potential mechanism of high fat diet function in allergic disease by Yanan Sun, Ning Liu, Huihui Wang, Taiqi Qu, Fazheng Ren, Yixuan Li

“…Acetylome analysis also revealed 32 differentially expressed proteins between the HFD and NFD groups. …”
Get full text

Natural capital accounting reveals ecosystems’ role in water and energy security in Colombia’s Sinú Basin by Lisa Mandle, Héctor Angarita, Jaime Moreno, Jesse A. Goldstein, Sioux F. Melo L, Alejandra Echeverri, Nicolas Rojas, Fabián Dario Villalba

Get full text

Transcriptional profiles of Microcystis reveal gene expression shifts that promote bloom persistence in in situ mesocosms by Lauren E. Krausfeldt, Paisley S. Samuel, Robert P. Smith, Hidetoshi Urakawa, Barry H. Rosen, Rita R. Colwell, Jose V. Lopez

Get full text

Local haplotyping reveals insights into the genetic control of flowering time variation in wild and domesticated soybean by Shameela Mohamedikbal, Hawlader A. Al‐Mamun, Jacob I. Marsh, Shriprabha Upadhyaya, Monica F. Danilevicz, Henry T. Nguyen, Babu Valliyodan, Adam Mahan, Jacqueline Batley, David Edwards

Get full text

Genome sequencing reveals novel variants in a diverse population with congenital anterior segment anomalies by Ashraf Hussain, Maria Fernanda Villalba, Dayna Morel Swols, Rayan Abou Khzam, Brittney Keira Johnson, LéShon Peart, Sarha D’Haiti, Alana L. Grajewski, Mustafa Tekin, Ta Chen Chang, Guney Bademci

Get full text

Unsupervised clustering of biochemical markers reveals health profiles associated with function and survival in active aging by Raquel González-Martos, Javier Galeano, Carmen Ramirez-Castillejo, Narcis Gusi, Eva Gesteiro, German Vicente-Rodriguez, Ignacio Ara, Amelia Guadalupe-Grau

Get full text

SARS-CoV-2 variants reveal features critical for replication in primary human cells. by Marie O Pohl, Idoia Busnadiego, Verena Kufner, Irina Glas, Umut Karakus, Stefan Schmutz, Maryam Zaheri, Irene Abela, Alexandra Trkola, Michael Huber, Silke Stertz, Benjamin G Hale

“…Strikingly, low-passage Vero-derived stock preparation of 3 SARS-CoV-2 isolates selected for substitutions at positions 5/6 of E and were highly attenuated in BEpCs, revealing a key cell-specific function to this region. …”
Get full text

Virome profiling of Aedes albopictus across urban ecosystems in Guangdong reveals sex-specific diversity by Qianlin Li, Jicheng Huang, Yanrong Zhou, Qin Wu, Jian Zhou, Fengxia He, Lirun He, Yongxia Shi, Cheng Guo, Jun Dai

“…Conclusions This study presents the inaugural comparative analysis of DNA/RNA viromes in Aedes albopictus populations across Guangdong Province, revealing distinct sex-specific and geographic patterns in viral composition. …”
Get full text

Ultrafast fMRI reveals serial queuing of information processing during multitasking in the human brain by Qiuhai Yue, Allen T. Newton, René Marois

Get full text