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Acute manipulation of diacylglycerol reveals roles in nuclear envelope assembly & endoplasmic reticulum morphology.
Published 2012-01-01“…Acute and inducible DAG depletion results in failure of the nuclear envelope (NE) to reform at mitosis and reorganisation of the ER into multi-lamellar sheets as revealed by correlative light and electron microscopy and 3D reconstructions. …”
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Phosphorus Variations in Volcanic Sequences Reveal the Linkage Between Regional Tectonics and Terrestrial Biota Evolution
Published 2022-08-01“…Here, we show that the secular variation of P availability in the Mesozoic volcanic rocks were the immediate results of the changes in volcanic intensity and lithospheric thickness controlled by the geological background of the cratonic destruction resulting from the paleo‐Pacific plate subduction. This study reveals the constraint effect of regional tectonics on the evolution of terrestrial ecosystems through the volcanism and P cycle.…”
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Multidimensional analysis reveals gene expression, cell interactions, and signaling networks in glioma and Alzheimer’s disease
Published 2025-02-01“…Principal Component Analysis (PCA) and dimensionality reduction techniques like UMAP and t-SNE reveal cell population heterogeneity and potential subgroups. …”
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Spatial transcriptomics reveal high T cell and monocyte status as predictive and prognostic markers in pancreatic cancer
Published 2025-05-01“…Multivariate analysis revealed age, high monocyte infiltration, and high CD68-positive cell infiltration as independent prognostic factors for overall survival. …”
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Telomere-to-telomere genome assembly of a male goat reveals variants associated with cashmere traits
Published 2024-11-01“…Also, our analyses reveal a set of selective variants and genes associated with domestication (e.g., NKG2D and ABCC4) and cashmere traits (e.g., ABCC4 and ASIP).…”
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TCR and BCR repertoire analysis reveals distinct signatures between benign and malignant ovarian tumors
Published 2025-08-01“…Moreover, a comparison of the spatial distributions of TCR and BCR revealed, for the first time, that TCR was more significantly associated with the benign-to-malignant transformation of ovarian tumors.ConclusionsOur study highlights the critical role of the adaptive immune repertoire in distinguishing between benign and malignant ovarian tumors. …”
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Hierarchical Regulatory Networks Reveal Conserved Drivers of Plant Drought Response at the Cell‐Type Level
Published 2025-05-01“…By analyzing nearly 30 000 multi‐omics data samples across species, unique insights are revealed into conserved drought responses and cell‐type‐specific regulatory dynamics, leveraging novel integrative analytical workflows. …”
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Optogenetics reveals Cdc42 local activation by scaffold-mediated positive feedback and Ras GTPase.
Published 2020-01-01“…These cells further revealed that the small GTPase Ras1 plays a role in both localizing the GEF Scd1 and promoting its activity, which potentiates the positive feedback. …”
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Whole genome resequencing reveals the evolutionary history and geographic isolation of the eastern Asian Hickory (Carya)
Published 2024-11-01“…Phylogenetic analysis of Carya revealed two distinct clades, separating EA Carya from NA (North America) Carya. …”
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Proteomic analysis reveals dynamic expression related to malondialdehyde in cassava in response to cassava bacterial blight
Published 2025-07-01“…Understanding tolerant cultivar responses can reveal key disease resistance mechanisms. This study identified differentially abundant proteins between the tolerant ‘Rayong72’ (R72) and susceptible ‘Hanatee’ (HN) cassava cultivars, with quantitative PCR validating mRNA-level changes. …”
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Pan-Cancer Analysis Reveals PRIM2 as a Potential Biomarker for Diagnosis, Prognosis, and Immunomodulatory
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Universal multilayer network embedding reveals a causal link between GABA neurotransmitter and cancer
Published 2025-06-01Get full text
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Single-cell analysis of mature hepatocytes reveals an IRF1-driven restriction of HDV infection
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Revealing Physical Mechanisms of Spatial Pattern Formation and Switching in Ecosystems via Nonequilibrium Landscape and Flux
Published 2025-07-01“…The emergence of pattern switching is revealed through the optimal pathways and how fast this occurs via the speed of pattern switching. …”
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Magmatic Carbon and Helium in Springs Reveals the Vitality of a Dormant Volcano, Taranaki, New Zealand
Published 2022-09-01“…Cold spring geochemistry thus reveals volcanic activity at this dormant volcano that otherwise lacks obvious geophysical signs of unrest.…”
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