Directed Connectivity Analysis of the Neuro-Cardio- and Respiratory Systems Reveals Novel Biomarkers of Susceptibility to SUDEP by T. Noah Hutson, Farnaz Rezaei, Nicole M. Gautier, Jagadeeswaran Indumathy, Edward Glasscock, Leonidas Iasemidis

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Morphological Insights into <i>Echinometra lucunter</i> Spines Reveal Cellular Sources of Bioactive Molecules by Juliana Mozer Sciani, Marta Maria Antoniazzi, Carlos Jared, José Roberto Machado Cunha da Silva, Daniel Carvalho Pimenta

“…Using various microscopy techniques, the spines were revealed to be mineral structures with longitudinal canals and a sponge-like central mesh rich in granular cells. …”
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Integrated analysis reveals that EGR1 promotes epithelial IL33 production in T2 asthma by Yan Zhao, Jenil Patel, Jinhua Fan, Xinyang Wang, Lin Chen, Yuanyuan Li, Zhengxiu Luo

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Integrative proteomics and metabolomics reveal important pathways and potential biomarkers in high-altitude pulmonary hypertension by Zhuo-ga Dan-zeng, Yang-jin Bai-ma, Ju Huang, Wang-jie Suo-lang, Qu-zhen Ge-sang, Yang-zong Suo-na, Yuan-sheng Wang, Zhuo-ga Baima, luo-bu Ge-sang

“…Our integrated multi-omics analysis reveals a complex molecular network underlying HAPH pathogenesis, characterized by coordinated changes in lipid metabolism, immune function, and cellular structure. …”
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STAT3‐dependent analysis reveals PDK4 as independent predictor of recurrence in prostate cancer by Monika Oberhuber, Matteo Pecoraro, Mate Rusz, Georg Oberhuber, Maritta Wieselberg, Peter Haslinger, Elisabeth Gurnhofer, Michaela Schlederer, Tanja Limberger, Sabine Lagger, Jan Pencik, Petra Kodajova, Sandra Högler, Georg Stockmaier, Sandra Grund‐Gröschke, Fritz Aberger, Marco Bolis, Jean‐Philippe Theurillat, Robert Wiebringhaus, Theresa Weiss, Andrea Haitel, Marc Brehme, Wolfgang Wadsak, Johannes Griss, Thomas Mohr, Alexandra Hofer, Anton Jäger, Jürgen Pollheimer, Gerda Egger, Gunda Koellensperger, Matthias Mann, Brigitte Hantusch, Lukas Kenner

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Comparative transcriptome profiling reveals that light coordinates auxin to inhibit adventitious root formation in grapevine by Yunzhang Yuan, Miao Bai, Peiyi Ni, Yanxia Li, Xinyu Chang, Jingjing He, Guoshun Yang, Shuangjiang Li

“…In this study, we applied an efficient and convenient leave-petiole (LP) system for studying ARs, revealing a significant inhibition of root primordia formation under continuous-light treatment. …”
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Ancient DNA reveals diverse community organizations in the 5th millennium BCE Carpathian Basin by Anna Szécsényi-Nagy, Cristian Virag, Kristóf Jakab, Nadin Rohland, Harald Ringbauer, Alexandra Anders, Pál Raczky, Tamás Hajdu, Krisztián Kiss, Tamás Szeniczey, Sándor Évinger, Tamás Keszi, Zsuzsanna M. Virág, Olivia Cheronet, Swapan Mallick, Ali Akbari, Ron Pinhasi, David Reich, Zsuzsanna Siklósi

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Integrative omics analysis reveals the genetic basis of fatty acid composition in Brassica napus seeds by Yuting Zhang, Yunhao Liu, Zhanxiang Zong, Liang Guo, Wenhao Shen, Hu Zhao

“…Experimental validation reveals that four genes (BnaA09.PYRD, BnaA08.PSK1, BnaA08.SWI3, and BnaC02.LTP15) positively modulate oleic acid content while negatively impact erucic acid content. …”
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Epigenome-wide analysis reveals potential biomarkers for radiation-induced toxicity risk in prostate cancer by Carlos Lopez-Pleguezuelos, Miguel E. Aguado-Barrera, Ana Carballo-Castro, Paula Peleteiro, Patricia Calvo-Crespo, Begoña Taboada-Valladares, Ramón Lobato-Busto, Olivia Fuentes-Ríos, Javier Galego-Carro, Carla Coedo-Costa, Antonio Gómez-Caamaño, Ana Vega

“…Identifying such biomarkers could reveal molecular mechanisms underlying RT response and enable personalized treatment. …”
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The molecular signature of heat stress in sweat reveals non-invasive biomarker candidates for health monitoring by Noé Brasier, Carmela Niederberger, Martina Zanella, Alaa Othman, Ralph Schlapbach, Laura Kunz, Antje Dittmann, Kelly Reeve, Michael Prummer, Jörg Goldhahn

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Self-supervised learning reveals clinically relevant histomorphological patterns for therapeutic strategies in colon cancer by Bojing Liu, Meaghan Polack, Nicolas Coudray, Adalberto Claudio Quiros, Theodore Sakellaropoulos, Hortense Le, Afreen Karimkhan, Augustinus S. L. P. Crobach, J. Han J. M. van Krieken, Ke Yuan, Rob A. E. M. Tollenaar, Wilma E. Mesker, Aristotelis Tsirigos

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The local-scale populations reveal cryptic processes occurring in the general population of Schizophyllum commune fungus by Sergiy Boiko

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The spatial transcriptome of the late-stage embryonic and postnatal mouse brain reveals spatiotemporal molecular markers by Yuichiro Hara, Takuma Kumamoto, Naoko Yoshizawa-Sugata, Kumiko Hirai, Xianghe Song, Hideya Kawaji, Chiaki Ohtaka-Maruyama

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Transcriptome analysis of Colletotrichum nymphaeae-Strawberry interaction reveals in planta expressed genes associated with virulence by Egem Ozbudak, Egem Ozbudak, Yisel Carrillo-Tarazona, Edinson A. Diaz, Flavia T. Zambon, Lorenzo Rossi, Natalia A. Peres, Sylvain Raffaele, Liliana M. Cano

“…Transcriptomic profiling revealed a set of genes encoding secreted effector proteins, including NUDIX hydrolase and LysM domain-containing proteins. …”
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Transcriptome reveal gene regulation mechanisms of the barnacle Chthamalus challengeri for microhabitat adaption in the intertidal zone by HaoYuan Li, MengMeng Huang, ZhiBin Gan, XinZheng Li

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Proteomic profiling reveals important regulators of photosynthate accumulation in wheat leaves during grain development by Wanting Li, Xiangrui Liu, Zeyu Shi, Yifei Wang, Wenqiang Tang, Huimin Ren, Baowen Zhang

“…Addressing this gap could reveal novel targets for enhancing carbohydrate partitioning efficiency and improving agronomic yield in wheat. …”
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Mathematical modeling reveals ferritin as the strongest cellular driver of dietary iron transfer block in enterocytes. by Joseph Masison, Pedro Mendes

“…The model is then used to estimate the quantitative contribution of each of the three mechanisms on the properties of the mucosal block. Analysis reveals that ferritin and iron regulatory proteins are the main intracellular mechanisms contributing to the mucosal block, findings congruent with experimental predictions. …”
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Infection with Angiostrongylus cantonensis reveals up- and down-regulation of the protein profile in the mucus of infected slugs by Joana Borges Osório, Giovanni Gosch Berton, Leandro Mattos Pereira, Jeremy Potriquet, Renata Russo F. Cândido, Jason Mulvenna, Malcolm K. Jones, Carlos Graeff-Teixeira, Alessandra Loureiro Morassutti

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Revealing the "short board effect" of the angle of repose of non-cohesive mixed sand based on experiments by YUAN Qiang, RAO Zhangchao, LUO Yongqin, WANG Chengdi, FU Junfeng, SUN Fanfan

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Resting-State fMRI Reveals the Neural Correlates of Acupuncture in the Treatment of Vascular Cognitive Impairment by Liu Q, Xiao K, Wan P, Zou Q

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