Comparative genomics profiling of Citrus species reveals the diversity and disease responsiveness of the GLP pangenes family by Muhammad Tahir ul Qamar, Kinza Fatima, Muhammad Junaid Rao, Qian Tang, Muhammad Sadaqat, Baopeng Ding, Ling-Ling Chen, Xi-Tong Zhu

“…The comparative genomics analysis revealed the presence-absence variations (PAVs) among the Citrus genomes and species-specific protein-coding genes. …”
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Sequencing of historical plastid genomes reveal exceptional genetic diversity in early domesticated rye plants by Jovan Komluski, Sofia Filatova, Frank Schlütz, Benjamin Claaßen, Manfred Rösch, Ben Krause-Kyora, Wiebke Kirleis, Eva H. Stukenbrock

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Comprehensive behavioral phenotyping of male Septin 3-deficient mice reveals task-specific abnormalities by Natsumi Ageta-Ishihara, Keizo Takao, Tsuyoshi Miyakawa, Makoto Kinoshita

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Viral metagenomics reveals parvovirus dark matter of herbivorous wildlife from the Qinghai-Tibet Plateau by Yue Chen, Shiyin Huang, Xiang Lu, Likai Ji, Quan Shen, Shixing Yang, Yuwei Liu, Xiaochun Wang, Ping Wu, Hongfeng Yang, Tongling Shan, Wen Zhang

“…Conclusions These results enrich our understanding of parvovirus and viral dark matter, and reveal that these wild animals carry a large number of unknown new viruses that may have implications for the ecological balance of the Qinghai-Tibet Plateau.…”
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Metabolomic profiling reveals systemic metabolic disruptions induced by combined exposure to particulate matter and ozone by Yue Ge, Maliha S. Nash, Aimen K. Farraj

“…Principal component analysis revealed overlapping profiles between CAPs and controls, indicating a subtler impact of CAPs compared to ozone or combined exposure. …”
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Genomic evidence of hybridization between two species of Penduline Tits reveals postzygotic reproductive isolation by Hui Wang, Mansour Aliabadian, Zhengwang Zhang, De Chen

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Cerebrospinal Fluid Proteomic Profiling Reveals Proteins Associated with Neuroinflammatory Response in COVID-19 Patients by Juliana Ramos de Andrade, Josivan Barbosa de Farias, Maria Luiza de Lima Vitorino, Fernando Tenório Travassos, Roberto Afonso da Silva, José Luiz de Lima Filho, Marcelo Moraes Valença

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Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity by Oded Shaham, Ru Wei, Thomas J Wang, Catherine Ricciardi, Gregory D Lewis, Ramachandran S Vasan, Steven A Carr, Ravi Thadhani, Robert E Gerszten, Vamsi K Mootha

“…The metabolite dynamics also revealed insulin's known actions along four key axes—proteolysis, lipolysis, ketogenesis, and glycolysis—reflecting a switch from catabolism to anabolism. …”
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Revealing the Relationship Between Macrostructures and Inclusions Across the Thickness Direction of Q235B Slabs by Bo Wang, Jinwen Jin, Chao Gu, Ze Wei, Ziyu Lyu, Lidong Xing, Yanping Bao

“…Hence, in this paper, the relationship between macrostructures and inclusions was revealed by laboratory experiments and theoretical calculations. …”
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Integrative multiomics analysis reveals host-microbe-metabolite interplays associated with the aging process in Singaporeans by Liwei Chen, Tingting Zheng, Yifan Yang, Prem Prashant Chaudhary, Jean Pui Yi Teh, Bobby K. Cheon, Daniela Moses, Stephan C. Schuster, Joergen Schlundt, Jun Li, Patricia L. Conway

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Revealing the microstructural brain damage in amyotrophic lateral sclerosis: the relentless pursuit to approach an imaging biomarker by Antônio José da Rocha, Marco Antonio Chieia

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Corrigendum to: Single-cell RNA sequencing reveals the effects of hederasaponin C in the treatment of diabetic nephropathy by Jing Liu, Qian Zhang, Wentong Zhao, Jinan Guo, Yin Kwan Wong, Chunting Zhang, Weijin Qiu, Piao Luo, Junhui Chen, Junmao Li, Xiaoran Li, Hongwei Gao, Shilin Yang, Yulin Feng, Jigang Wang

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Machine learning reveals distinct neuroanatomical signatures of cardiovascular and metabolic diseases in cognitively unimpaired individuals by Sindhuja Tirumalai Govindarajan, Elizabeth Mamourian, Guray Erus, Ahmed Abdulkadir, Randa Melhem, Jimit Doshi, Raymond Pomponio, Duygu Tosun, Murat Bilgel, Yang An, Aristeidis Sotiras, Daniel S. Marcus, Pamela LaMontagne, Tammie L. S. Benzinger, Mark A. Espeland, Colin L. Masters, Paul Maruff, Lenore J. Launer, Jurgen Fripp, Sterling C. Johnson, John C. Morris, Marilyn S. Albert, R. Nick Bryan, Susan M. Resnick, Mohamad Habes, Haochang Shou, David A. Wolk, Ilya M. Nasrallah, Christos Davatzikos

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Brain Network Analysis Reveals Age-Related Differences in Topological Reorganization During Vigilance Decline by Lingyun Gao, Rui Zhang, Mengru Xu, Yi Sun, Gang Li, Yu Sun

“…Specifically, significant deficits in nodal efficiency were revealed in most of the brain regions, and the frontal area exhibited significant age-by-time interaction effect, which was attributed to a significant decline in the elderly group. …”
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Scanning electron diffraction reveals the nanoscale ordering of cellulose in a hierarchically structured hybrid material by Nero Mathias, Ali Hasan, Li Yuanyuan, Willhammar Tom

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Multi-omics analysis reveals the sensitivity of immunotherapy for unresectable non-small cell lung cancer by Rui Wu, Kunchen Wei, Xingshuai Huang, Yinge Zhou, Xiao Feng, Xin Dong, Hao Tang

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OSaMPle workflow for salivary metaproteomics analysis reveals dysbiosis in inflammatory bowel disease patients by Jinhui Yuan, Boyan Sun, Murong Li, Congyi Yang, Lingqiang Zhang, Ning Chen, Feng Chen, Leyuan Li

“…Furthermore, applying OSaMPle to analyze mouth rinse samples from IBD patients revealed significant alterations in bacterial protein expressions under disease conditions. …”
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Earth observations reveal impacts of climate variability on maize cropping systems in sub-Saharan Africa by Adomas Liepa, Michael Thiel, Hannes Taubenböck, Doris Klein, Ingolf Steffan-Dewenter, Marcell K. Peters, Sarah Schönbrodt-Stitt, Insa Otte, Tobias Landmann, Zeyaur R. Khan, Michael Ochieng Obondo, Frank Chidawanyika, Emily A. Martin, Tobias Ullmann

“…Field data from 58 sites in southwestern Kenya provided training for this analysis, revealing detectable inter-class differences. Notably, Push-Pull intercrop fields showed greater resilience during biotic stress events, such as the locust outbreak in 2020 short rainy season and the fall armyworm infestation in combination with delayed and below-average rainfall during the short 2021 and the long 2022 growing seasons. …”
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In-vivo Raman microspectroscopy reveals differential nitrate concentration in different developmental zones in Arabidopsis roots by Alma Fernández González, Ze Tian Fang, Dipankar Sen, Brian Henrich, Yukihiro Nagashima, Alexei V. Sokolov, Sakiko Okumoto, Aart J. Verhoef

“…Measurements are done in-situ without additional sample preparation. Our measurements revealed nitrate concentration changes from lower to higher concentration from tip to mature root tissue. …”
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The Spatial‐Temporal Alternative Splicing Profile Reveals the Functional Diversity of FXR1 Isoforms in Myogenesis by Wei Wang, Xinhao Fan, Weiwei Liu, Yuxin Huang, Shuhong Zhao, Yalan Yang, Zhonglin Tang

“…Here, the temporal AS profiles are investigated during myogenesis in five vertebrates, conducting comprehensive profiling across 27 developmental stages in skeletal muscle and encompassing ten tissues in adult pigs. The analysis reveals a pervasive and evolutionarily conserved pattern of alternative exon usage throughout myogenic differentiation, with hundreds of skipped exons (SEs) showing developmental regulation, particularly within skeletal muscle. …”
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