A Cross-Study Biomarker Signature of Human Bronchial Epithelial Cells Infected with Respiratory Syncytial Virus by Luiz Gustavo Gardinassi

“…Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infections in children, elderly, and immunocompromised individuals. …”
Get full text

Prevalence  of  Chronic  Otitis  Media  and  Its  Associated  Hearing  Impairment  among  School  Going  Children by Arun Maran Sattien, Priyokumar Singh Oinam, Mosin Babu, Shandyalata Yumlembam, Lalnunpuia Thangluah

“…This  study  revealed  statistically  significant  association  of  CSOM  with  parent  illiteracy,  overcrowding,  swimming  in  local  pools  and  recurrent  respiratory  tract  infections. Conclusion: Health  education  through  school  health  program,  improvement  of  socioeconomic  status  and  health  facilities  should  be  used  in  early  detection  and  management  of  this  disease  thereby  reducing  the  prevalence  of  CSOM. …”
Get full text

Learn from international recommendations and experiences of countries that have successfully implemented monoclonal antibody prophylaxis for prevention of RSV infection by Sara Manti, Eugenio Baraldi

“…Nirsevimab has been shown to be safe and effective (> 80%) against RSV lower respiratory tract infections (LRTIs) in all infants and children at their first season of RSV. …”
Get full text

Involvement of the TGF-β pathway in epithelialmesenchymal transition promoted by the pulmonary microenvironment in Mycoplasma pneumoniae pneumonia by Fan Lu, Wang Huixia, Xu Nuo, Guo Yun, Li Ling

“…Mycoplasma pneumoniae (MP), one of the smallest prokaryotic microorganisms capable of independent survival, causes respiratory tract infections and various extrapulmonary diseases. …”
Get full text

The effect of azithromycin treatment on respiratory morbidity in children with down syndrome by Inbal Golan-Tripto, Omer Dor, Noga Arwas, Itai Hazan, Guy Hazan, Aviv Goldbart

“…While Azithromycin has been increasingly used for lower-respiratory tract infections (LRTIs) in children, its potential benefits for DS patients are unexplored. …”
Get full text

Cultivation and molecular characterization of complete genome sequences of M. pneumoniae isolated in Russia by Matsvay A.D., Bezrukov V.M., Nikolaeva P.A., Stetsenko I.F., Nurmukanova V.A., Dikaya G.S., Gordukova M.A., Galeeva E.V., Shipulin G.A.

“…Despite being one of the primary causative agents of community-acquired lower respiratory tract infections in children, due to the difficulties in obtaining a culture of this pathogen, the amount of genomic data on M. pneumoniae is currently extremely limited, with fewer than 300 genomic sequences available, of which only 79 are complete. …”
Get full text

Human Neutrophil Defensin-1, -3, and -4 Are Elevated in Nasal Aspirates from Children with Naturally Occurring Adenovirus Infection by V. S. Priyadharshini, F. Ramírez-Jiménez, M. Molina-Macip, C. Renteria-Rosales, J. Santiago-Cruz, Paola Zarate-Segura, E. Lara-Padilla, Luis M. Teran

“…To investigate the release of HNP-1–4 in adenovirus infection and the relationship with self-limiting upper respiratory tract infections. Methods. Nasal aspirate samples (n=14) were obtained from children (aged 6–12 years) infected with adenovirus between June 2012 and December 2015. …”
Get full text

Real-world pharmacovigilance of ofatumumab in multiple sclerosis: a comprehensive FAERS data analysis by Hui Chen

“…The timing of adverse events was assessed using the Weibull distribution model to highlight temporal risk patterns.ResultsKnown adverse reactions, such as injection site reactions and upper respiratory tract infections, displayed positive signals. Additionally, novel off-label adverse events, including brain fog, muscle spasms, and mood alterations, were identified, marking the first real-world evidence of these potential risks. …”
Get full text

Application of ectoine in diseases of the skin and mucous membranes by Piotr Kuna, Dominika Ochab-Krupnik, Anna Mościcka, Piotr Łacwik

“…Ongoing trials confirming its supportive role in several inflammatory conditions are available, including, but not limited to upper respiratory tract infections, allergic rhinitis, chronic sinusitis, asthma, chronic obstructive pulmonary disease and ocular conditions. …”
Get full text

COMPARATIVE ASSESSMENT OF RATIONAL ANTIBIOTIC USAGE AMONG NON-PHYSICIAN HEALTH PROFESSIONALS AND LAY INDIVIDUALS by Ersan Gürsoy, Mehmet Vatansever

“…The study showed that healthcare workers and people who preferred to visit a healthcare facility for upper respiratory tract infections tended to have more negative attitudes towards antibiotic use (p=0.021 and p<0.001 respectively). …”
Get full text

IAPSM’s Position Paper on Influenza Vaccines for Adult Immunization in India by Nikita Sharma, Madhur Verma, Kapil Goel, Muralidhar M. Kulkarni, Anu Bhardwaj, Sahil Sharma, Tejbeer Singh, Madhu Gupta, Anuradha Nadda, Lalit R. Sankhe

“…Influenza causes significant morbidity, hospitalizations, and mortality due to lower respiratory tract infections in India. This paper reviews the current evidence regarding influenza epidemiology, the need for vaccination, immunogenicity, and efficacy of available vaccines and provides recommendations for influenza vaccination for adults by the Indian Association of Preventive and Social Medicine (IAPSM). …”
Get full text

Common variable immunodeficiency: An uncommon cause of bronchiectasis, granulomatous disease, chronic liver disease, and enteropathy – Case report and review of literature by Veena Shamsudeen, Arun Hegde, Uday Bhanu Kovilapu, Nisha Verma, Anurag Jain

“…Respiratory involvement occurs commonly in the form of recurrent upper and lower respiratory tract infections (LRTI), at times resulting in bronchiectasis. …”
Get full text

Severe IgG4-Related Disease in a Young Child: A Diagnosis Challenge by Susana Corujeira, Catarina Ferraz, Teresa Nunes, Elsa Fonseca, Luísa Guedes Vaz

“…We report the case of a 22-month-old female child with failure to thrive and recurrent respiratory tract infections since 8 months of age. Physical examination was normal except for pulmonary auscultation with bilateral crackles and wheezes. …”
Get full text

Evidence that a STAT3 Mutation Causing Hyper IgE Syndrome Leads to Repression of Transcriptional Activity by Sameer Bahal, Maha E. Houssen, Ania Manson, Lorena Lorenzo, Mark A. Russell, Noel G. Morgan, Fariba Tahami, Sofia Grigoriadou

“…Within the first years of life she developed multiple, Staphylococcus aureus associated abscesses in the neck and face requiring frequent incision and drainage. Respiratory tract infections were not a feature of the clinical phenotype and a high resolution thoracic CT scan was unremarkable. …”
Get full text

The recent landscape of RSV vaccine research by Karen Kelleher, Nadisha Subramaniam, Simon B. Drysdale

“…Infants, especially those born prematurely or with underlying health conditions, face a high risk of severe RSV-related lower respiratory tract infections (LRTIs). Globally, RSV contributes to millions of LRTI cases annually, with a disproportionate burden in low- and middle-income countries (LMICs). …”
Get full text

Phylogeny, Phytomedicines, Phytochemistry, Pharmacological Properties, and Toxicity of Croton gratissimus Burch (Euphorbiaceae) by Kirkland Dingili Magwilu, Joseph Mwanzia Nguta, Isaac Mapenay, Dorine Matara

“…It has been used to treat different ailments ranging from respiratory tract infections, urinary tract infections, malaria, diabetes, hypertension, dermatological conditions, arthritis, gastrointestinal disorders, fever, sexually transmitted diseases, and infertility. …”
Get full text

Evaluation of antibiotic treatment initiation and duration practices in primary care. Cross-sectional study in two French multi-professional health centers. by Simon Ferme, Emmanuel Piednoir, Marianne Delestre, Elise Fiaux, Johann Masik, Renaud Verdon, Pascal Thibon

“…In France, which ranks among the highest consumers of antibiotics in Europe, 93% of prescriptions are issued in primary care, primarily for respiratory tract infections. It is crucial to limit both the indications and the duration of antibiotic prescriptions, with recently updated recommendations in France aimed at achieving this goal. …”
Get full text

Why Does Pnemococcus Kill? by Yves Bergeron, Michel G Bergeron

“…Acute lower respiratory tract infections remain the most common cause of death due to infection worldwide, and Streptococcus pneumoniae is responsible for approximately 30% of all cases of community-acquired pneumonia. …”
Get full text

A Case Study on Strategic Multi-Objective Optimization of Influenza Vaccine Allocation: Age-Specific Approaches in Saudi Arabia by Asma K. Alkhamis, Manar I. Hosny

“…Acute lower respiratory tract infections pose a significant health challenge, affecting over 15% of Saudi Arabia’s population annually. …”
Get full text

Mycoplasma pneumoniae detections in children with acute respiratory infection, 2010–2023: a large sample study in China by Yuzhu Miao, Jungen Li, Linlin Huang, Ting Shi, Tingbo Jiang

“…Abstract Background This study aimed to describe the epidemiological trends of Mycoplasma pneumoniae (MP) infection among children with acute respiratory tract infections (ARTIs) before, during and after the COVID-19 pandemic, and evaluating the impact of non-pharmaceutical interventions (NPIs) on the epidemiology of MP infection. …”
Get full text