Severe IgG4-Related Disease in a Young Child: A Diagnosis Challenge by Susana Corujeira, Catarina Ferraz, Teresa Nunes, Elsa Fonseca, Luísa Guedes Vaz

“…We report the case of a 22-month-old female child with failure to thrive and recurrent respiratory tract infections since 8 months of age. Physical examination was normal except for pulmonary auscultation with bilateral crackles and wheezes. …”
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Evidence that a STAT3 Mutation Causing Hyper IgE Syndrome Leads to Repression of Transcriptional Activity by Sameer Bahal, Maha E. Houssen, Ania Manson, Lorena Lorenzo, Mark A. Russell, Noel G. Morgan, Fariba Tahami, Sofia Grigoriadou

“…Within the first years of life she developed multiple, Staphylococcus aureus associated abscesses in the neck and face requiring frequent incision and drainage. Respiratory tract infections were not a feature of the clinical phenotype and a high resolution thoracic CT scan was unremarkable. …”
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Phylogeny, Phytomedicines, Phytochemistry, Pharmacological Properties, and Toxicity of Croton gratissimus Burch (Euphorbiaceae) by Kirkland Dingili Magwilu, Joseph Mwanzia Nguta, Isaac Mapenay, Dorine Matara

“…It has been used to treat different ailments ranging from respiratory tract infections, urinary tract infections, malaria, diabetes, hypertension, dermatological conditions, arthritis, gastrointestinal disorders, fever, sexually transmitted diseases, and infertility. …”
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Why Does Pnemococcus Kill? by Yves Bergeron, Michel G Bergeron

“…Acute lower respiratory tract infections remain the most common cause of death due to infection worldwide, and Streptococcus pneumoniae is responsible for approximately 30% of all cases of community-acquired pneumonia. …”
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A Case Study on Strategic Multi-Objective Optimization of Influenza Vaccine Allocation: Age-Specific Approaches in Saudi Arabia by Asma K. Alkhamis, Manar I. Hosny

“…Acute lower respiratory tract infections pose a significant health challenge, affecting over 15% of Saudi Arabia’s population annually. …”
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Mycoplasma pneumoniae detections in children with acute respiratory infection, 2010–2023: a large sample study in China by Yuzhu Miao, Jungen Li, Linlin Huang, Ting Shi, Tingbo Jiang

“…Abstract Background This study aimed to describe the epidemiological trends of Mycoplasma pneumoniae (MP) infection among children with acute respiratory tract infections (ARTIs) before, during and after the COVID-19 pandemic, and evaluating the impact of non-pharmaceutical interventions (NPIs) on the epidemiology of MP infection. …”
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Can We Reduce Postoperative Airway Symptoms Related To Endotracheal Intubation In Elective General Anesthesia? by Sehrish Asad, Muhammad Ali, Saleem Ahmed, Faheem Feroze, Sadia Chaudhry, Nighat Qamar

“…Patients undergoing ENT /oral cavity / oropharyngeal surgeries and upper respiratory tract infections were excluded. Patients were divided into two groups. …”
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Community responses to a novel house design: A qualitative study of "Star Homes" in Mtwara, southeastern Tanzania. by Salum Mshamu, Judith Meta, Bipin Adhikari, Salma Halifa, Arnold Mmbando, Hannah Sloan Wood, Otis Sloan Wood, Thomas Chevalier Bøjstrup, Nicholas P J Day, Steven W Lindsay, Jakob Knudsen, Jacqueline Deen, Lorenz von Seidlein, Christopher Pell

“…<h4>Introduction</h4>To evaluate the impact of a novel design "Star Home" on the incidence of malaria, respiratory tract infections and diarrheal diseases among children, randomly selected households in Mtwara, Tanzania were offered a free, new Star Home. …”
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Corynebacteria from the respiratory microbiota modulate inflammatory responses and associate with a reduced pneumococcal burden in the lungs by Caroline Bergenfelz, Phuong Do, Liv Larsson, Hanna Ivarsson, Kasper Malmborn, Anders P. Håkansson

“…Corynebacterium propinquum and C. pseudodiphtheriticum (Corynebacteria) are two Gram-positive species that frequently colonize the upper respiratory tract and strongly associate with a reduced incidence of respiratory tract infections. The specific role of Corynebacteria during respiratory health and disease is, however, largely uncharacterized.MethodRespiratory tract epithelial cells NCI-H292 and BALB/cByJ mice were inoculated with Corynebacteria (C. propinquum 2018M3 and 2019M4, and C. pseudodiphtheriticum 2019M8 and 2020M12) alone or with subsequent challenge with Streptococcus pneumoniae (pneumococci). …”
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Gangguan Fungsi Penghidu dan Pemeriksaannya by Effy Huriyati, Tuti Nelvia

“…Disease that often causes disturbances of olfactory function is, chronic rhinosinusitis, allergic rhinitis, upper respiratory tract infections and head trauma. There are several modalities to examine chemosensoris smelling function, one of them is “Sniffin sticks” test. …”
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Characteristics of pediatric patients with febrile convulsions admitted to a tertiary care hospital in Riyadh, Saudi Arabia by Alanoud A. Abuhaimed, Nawaf A. Alghamdi, Ghadah I. Alhussin, Ghadah S. Alduhaimi, Fatmah Othman, Duaa M. Baarmah, Hamad A. Alkhalaf

“…Most of the patients (77%) convulsions were triggered by upper respiratory tract infections and median duration of the convulsion episode was 4 min; 55% of the patients had a simple FC, and 40% had recurrence of FCs. …”
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Comparisons of CVID and IgGSD: Referring Physicians, Autoimmune Conditions, Pneumovax Reactivity, Immunoglobulin Levels, Blood Lymphocyte Subsets, and HLA-A and -B Typing in 432 Ad... by James C. Barton, Luigi F. Bertoli, J. Clayborn Barton

“…Common variable immunodeficiency (CVID) and immunoglobulin (Ig) G subclass deficiency (IgGSD) are heterogeneous disorders characterized by respiratory tract infections, selective Ig isotype deficiencies, and impaired antibody responses to polysaccharide antigens. …”
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Investigation of Antibiotic Resistance and Biofilm Formation in Clinical Isolates of Klebsiella pneumoniae by Kiana Karimi, Omid Zarei, Parinaz Sedighi, Mohammad Taheri, Amin Doosti-Irani, Leili Shokoohizadeh

“…Our findings emphasize the need for proper diagnosis, control, and treatment of infections caused by K. pneumoniae especially in respiratory tract infections due to the strong biofilm formation and high antibiotic resistance in these strains.…”
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Isolation, genetic, and biological characterization of human adenovirus type 55 positive isolates from Wuhan, China by Jing Xie, Yan Wang, Huan Li, Bingxiu Tan, Zhengying Yu, Lizhong Li, Wei Zhang, Hongbin Song, Leili Jia

“…Infections by HAdV-55, one of the important pathogens leading to respiratory tract infections, often develop into pneumonia and are frequently associated with outbreaks in military camps and schools. …”
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Anti-Idiotypic Antibody as a Booster Vaccine Against Respiratory Syncytial Virus by Shreya Mukhopadhyay, Ioannis Manolaridis, Christopher Warren, Aimin Tang, Gregory O’Donnell, Bin Luo, Ryan P. Staupe, Kalpit A. Vora, Zhifeng Chen

“…<b>Background/Objectives:</b> The respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infections in children and adults. With nearly everyone infected by the age of five, there is an opportunity to develop booster vaccines that enhance B-cell immunity, promoting potent and broadly neutralizing antibodies. …”
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Relationship between RSV-hospitalized children and meteorological factors: a time series analysis from 2017 to 2023 by Shuying Wang, Yifan Wang, Yingxue Zou, Cheng-liang Yin

“…Abstract Objectives Respiratory syncytial virus (RSV) is a leading cause of hospitalization for lower respiratory tract infections amongst infants under 1 year, posing a significant global health challenge. …”
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DNAH11 and a Novel Genetic Variant Associated with Situs Inversus: A Case Report and Review of the Literature by Fatemeh Sodeifian, Noosha Samieefar, Sepideh Shahkarami, Elham Rayzan, Simin Seyedpour, Meino Rohlfs, Christoph Klein, Delara Babaie, Nima Rezaei

“…A 3-year-old boy, the offspring of consanguineous parents, was referred to the pediatric clinical immunology outpatient department with a history of recurrent respiratory tract infections and periodic fever. Furthermore, on medical examination, situs inversus was recognized. …”
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Economic and clinical burden associated with respiratory syncytial virus and impact of universal immunization with nirsevimab in Italy by Andrea Marcellusi, Chiara Bini, Barbara Muzii, Samira Soudani, Alexia Kieffer, Matthieu Beuvelet, Elena Bozzola, Fabio Midulla, Eugenio Baraldi, Paolo Bonanni, Sara Boccalini, Luigi Orfeo

“…Methods: A static decision analytic model previously used in the US was adapted to evaluate the RSV-related health and cost outcomes associated with nirsevimab versus standard of care (SoC) for the prevention of RSV medically attended lower respiratory tract infections (RSV-MA-LRTIs). Monthly probabilities of RSV infections, health events, mortality, and complications associated with RSV infections were obtained from the literature. …”
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An X-Linked Hyper-IgM Patient Followed Successfully for 23 Years without Hematopoietic Stem Cell Transplantation by Necil Kutukculer, Neslihan Edeer Karaca, Guzide Aksu, Ayca Aykut, Erhan Pariltay, Ozgur Cogulu

“…A seven-year-old male patient was admitted with recurrent upper and lower respiratory tract infections and recurrent otitis media. His initial immunologic evaluation revealed low IgG and normal IgA and IgM levels with normal lymphocyte phenotyping and inadequate specific antibody responses. …”
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Development and evaluation of a recombinant monoclonal human antibody with virus-neutralizing activity against the F glycoprotein of respiratory syncytial virus by Sergey A. Klotchenko, Ekaterina A. Romanovskaya-Romanko, Marina A. Plotnikova, Anastasia A. Pulkina, Aram A. Shaldzhyan, Dmitry S. Balabashin, Victoria A. Toporova, Teimur K. Aliev, Natalia E. Gyulikhandanova, Dmitry A. Lioznov

“…Respiratory syncytial virus (RSV) is the most common pathogen causing lower respiratory tract infections in children. RSV also poses a serious threat to the elderly and immunocompromised patients. …”
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