Epigenetic modifications and emerging therapeutic targets in cardiovascular aging and diseases by Yurou Qiu, Qing Xu, Peichen Xie, Chenshuang He, Qiuchan Li, Xin Yao, Yang Mao, Xiaoqian Wu, Tiejun Zhang

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Associations of sedentary time, sleep duration and physical exercise with multimorbidity among older adults in Shanghai, China: a cross-sectional study based on national physical f... by Kai Li, Jingjing Wang, Yuqin Rao, Fanhui Zheng, Ying Chen, Bo Zhai, Jintao Hong, Dao Wang, Chen Wang, Bao Liu

“…Prolonged sedentary behavior and shorter sleep duration were associated with membership in the metabolic-cardiovascular-joint-digestive-respiratory disease class, the metabolic-cardiovascular disease class, and the joint-digestive-respiratory disease class. …”
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DNA hypomethylation-mediated upregulation of GADD45B facilitates airway inflammation and epithelial cell senescence in COPD by Yuan Zhan, Qian Huang, Zhesong Deng, Shanshan Chen, Ruonan Yang, Jiaheng Zhang, Yating Zhang, Maocuo Peng, Jixing Wu, Yiya Gu, Zhilin Zeng, Jungang Xie

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Systematic bias between blinded independent central review and local assessment: literature review and analyses of 76 phase III randomised controlled trials in 45 688 patients with... by Jianrong Zhang, Yu Huang, Hengrui Liang, Wenhua Liang, Jianxing He, Yiyin Zhang, Jiaxi He, Jieyu Wu, Long Jiang, Shiyan Tang, Qihua He, Lindsey Tristine Hamblin, Zhiheng Xu, Yaoqi Chen, Difei Chen, Xinyu Wang, Kexin Deng, Shuhan Jiang, Jiaqing Zhou, Jiaxuan Xu, Xuanzuo Chen

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Inflammatory Mediators in Induced Sputum and Airway Hyperresponsiveness in Cough Variant Asthma during Long-Term Inhaled Corticosteroid Treatment by Meixuan Liu, Kaixiong Liu, Ning Zhu, Jingwen Xia, Xiaodong Chen

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Bleomycin pollution and lung health: The therapeutic potential of peimine in bleomycin-induced pulmonary fibrosis by inhibiting glycolysis by Kangchen Li, Xuefang Liu, Ruilong Lu, Peng Zhao, Yange Tian, Jiansheng Li

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Baricitinib treatment for hospitalized patients with severe COVID-19 on invasive mechanical ventilation: a propensity score-matched and retrospective analysis by Yanxiong Mao, Anyi Guo, Ying Zhang, Jianxing Lai, Dian Yuan, Hao Zhang, Wenqi Diao, Weisong Chen, Fugui Yan

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ALCAM is an entry factor for severe community acquired Pneumonia-associated Human adenovirus species B by Yusang Xie, Hong Mei, Wei Wang, Xiao Li, Pengfei Hu, Xingui Tian, Rong Zhou, Jia Liu, Jieming Qu

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Mechanisms of Copper-Induced Autophagy and Links with Human Diseases by Yuanyuan Fu, Shuyan Zeng, Zhenlin Wang, Huiting Huang, Xin Zhao, Min Li

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R-loop formation contributes to mTORC1 activation-dependent DNA replication stress induced by p53 deficiency by Li Xiaolei, Yang Cheng, Zhang Xiaohui, Wang Feiyang, Sun Longhua, Zhang Wei, Xu Xinping

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A modified screening protocol for ARDS in patients with respiratory support based on SpO2 and FiO2: A single-center prospective, observational study by Yan Xia, Qiancheng Xu, Zhiyuan Guo, Huijuan Zhang, Yingya Cao, Yupeng Qi, Qun Chen, Weihua Lu

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The Frequency of Mediastinal Lymph Node Calcification in Sarcoidosis Patients and the Influencing Factors by Pelin Pınar Deniz, Pelin Duru Çetinkaya, Saida Mehdiyeva, İsmail Hanta

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Clinical characteristics and prognosis of amyopathic dermatomyositis patients with interstitial lung disease: insights from a retrospective cohort by Yanan Ying, Tingting Wu, Long Wang, Yun Zhang, Yiming Yu, Zaichun Deng, Qunli Ding

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AXL: shapers of tumor progression and immunosuppressive microenvironments by Yihui Liu, Lei Xu, Yuanyao Dou, Yong He

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A Comparison of Work-Exacerbated Asthma Cases from Clinical and Epidemiological Settings by Paul K Henneberger, Xiaoming Liang, Catherine Lemière

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A nucleoside-modified mRNA vaccine prevents enterovirus A71 infection in mouse model by Fengyu Chi, Fengyu Chi, Xu Zhang, Xu Zhang, Dong Zhang, Dong Zhang, Airu Zhu, Zhen Zhuang, Zhaoyong Zhang, Zhenjie Zhang, Chuansong Quan, Kaixiao Nie, Juan Li, Chunhong Yin, Jie Tong, Yuming Li, Yuming Li, Yuming Li

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A novel non-invasive murine model for rapidly testing drug activity via inhalation administration against Mycobacterium tuberculosis by Xirong Tian, Xirong Tian, Xirong Tian, Xirong Tian, Yamin Gao, Yamin Gao, Yamin Gao, Yamin Gao, Chunyu Li, Chunyu Li, Chunyu Li, Chunyu Li, Wanli Ma, Wanli Ma, Wanli Ma, Wanli Ma, Jingran Zhang, Jingran Zhang, Jingran Zhang, Jingran Zhang, Yanan Ju, Yanan Ju, Yanan Ju, Yanan Ju, Jie Ding, Jie Ding, Jie Ding, Jie Ding, Sanshan Zeng, Sanshan Zeng, Sanshan Zeng, Sanshan Zeng, H. M. Adnan Hameed, H. M. Adnan Hameed, H. M. Adnan Hameed, H. M. Adnan Hameed, Htin Lin Aung, Htin Lin Aung, Htin Lin Aung, Nanshan Zhong, Gregory M. Cook, Gregory M. Cook, Gregory M. Cook, Gregory M. Cook, Jinxing Hu, Jinxing Hu, Tianyu Zhang, Tianyu Zhang, Tianyu Zhang, Tianyu Zhang, Tianyu Zhang

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Epithelial-mesenchymal transition in asthma: its role and underlying regulatory mechanisms by Bingxi Zhang, Bingxi Zhang, Xinru Feng, Lincha Tian, Bo Xiao, Lixia Hou, Biwen Mo, Biwen Mo, Biwen Mo, Dong Yao, Dong Yao, Dong Yao

“…Bronchial asthma (asthma) is a respiratory disease characterized by chronic inflammation, airway hyperresponsiveness, and airway remodeling. …”
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Predicting Time to First Rejection Episode in Lung Transplant Patients Using a Comprehensive Multi-Indicator Model by Chen Y, Li E, Yang Q, Chang Z, Yu B, Lu J, Wu H, Zheng P, Cheng ZJ, Sun B

“…Youpeng Chen,1,* Enzhong Li,2,* Qingqing Yang,1 Zhenglin Chang,1 Baodan Yu,1 Jiancai Lu,1 Haojie Wu,1 Peiyan Zheng,1 Zhangkai J Cheng,1,* Baoqing Sun1 1Department of Clinical Laboratory, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, 510140, People’s Republic of China; 2Department of Endocrinology, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhangkai J Cheng; Baoqing Sun, Department of Clinical Laboratory, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, 510140, People’s Republic of China, Email jasontable@gmail.com; sunbaoqing@vip.163.comBackground: Rejection hinders long-term survival in lung transplantation, and no widely accepted biomarkers exist to predict rejection risk. …”
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YAP K236 acetylation facilitates its nucleic export and deprived the protection against cardiac hypertrophy in mice by Panxia Wang, Luping Wang, Cui Liu, Yuehuai Hu, Guodong Feng, Zuqian Lian, Jing Lu, Ping He, Hexin Cai, Xiaohui Liang, Peiqing Liu, Xiaoqian Wu

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