Update on the Canadian Institutes of Health Research: Where Will Respiratory Health Research Fit in? by Malcolm King

“…The centre of attention has, of course, been the soon-to-be-established Canadian Institutes of Health Research (CIHR) and our Society's efforts to establish a position for respiratory research withing this new organization.…”
Get full text

Research priorities for preterm lung health research across the lifespan: a community priority setting partnership by Anne McKenzie, Shannon J Simpson, Naomi R Hemy, Amber Bates, Belinda Frank

Get full text

Editorial: Psychosocial issues and interventions in pulmonary rehabilitation by Ingeborg Farver-Vestergaard, Ingeborg Farver-Vestergaard, Eleonora Volpato, Eleonora Volpato, Eleonora Volpato, Henrik Hansen, Henrik Hansen, Henrik Hansen, Liz Steed

Get full text

Experiences of Oral Corticosteroid Use and Adverse Effects: A National Cross-Sectional Survey of People with Asthma by Jones AW, McDonald VM, McLoughlin RF, Vella TM, Flynn AW, Blakey JD, Wolfenden L, Hew M, Upham JW, Thomas D, Bardin P, Holland AE

“…Arwel W Jones,1 Vanessa M McDonald,2– 5 Rebecca F McLoughlin,2– 4 Teresa M Vella,6 Anthony W Flynn,7 John D Blakey,8,9 Luke Wolfenden,10,11 Mark Hew,12 John W Upham,13,14 Dennis Thomas,2,4 Philip Bardin,15 Anne E Holland1,2,16 1Respiratory Research@Alfred, Monash University, Melbourne, VIC, Australia; 2Centre of Excellence in Treatable Traits, University of Newcastle, Newcastle, NSW, Australia; 3School of Nursing and Midwifery, University of Newcastle, Newcastle, NSW, Australia; 4Hunter Medical Research Institute Asthma and Breathing Program, Newcastle, NSW, Australia; 5Department of Respiratory and Sleep Medicine, John Hunter Hospital, Newcastle, NSW, Australia; 6Brand and Engagement, Asthma Australia, Brisbane, QLD, Australia; 7Research, Information and Evaluation, Asthma Australia, Melbourne, VIC, Australia; 8Respiratory Medicine, Sir Charles Gairdner Hospital, Perth, WA, Australia; 9Medical School, Curtin University, Perth, WA, Australia; 10Hunter New England Population Health, Wallsend, NSW, Australia; 11School of Medicine and Public Health, University of Newcastle, Callaghan, NSW, Australia; 12Allergy, Asthma & Clinical Immunology, Alfred Health, Melbourne, VIC, Australia; 13Frazer Institute, University of Queensland, Brisbane, QLD, Australia; 14Department of Respiratory Medicine, Princess Alexandra Hospital, Brisbane, QLD, Australia; 15Monash Lung Sleep Allergy & Immunology, Monash University and Medical Centre, Clayton, VIC, Australia; 16Physiotherapy Department, Alfred Health, Melbourne, VIC, AustraliaCorrespondence: Arwel W Jones, Respiratory Research@Alfred, School of Translational Medicine, Monash University, Alfred Centre, Melbourne, VIC, 3004, Australia, Email arwel.jones@monash.eduPurpose: Oral corticosteroids (OCS) are an effective treatment for severe uncontrolled asthma or asthma exacerbations, but frequent bursts or long-term use carry serious and sometimes irreversible adverse effects, or complications such as adrenal insufficiency upon discontinuation. …”
Get full text

Prenatal and Postnatal Polycyclic Aromatic Hydrocarbon Exposure, Airway Hyperreactivity, and Beta-2 Adrenergic Receptor Function in Sensitized Mouse Offspring by Sophie Chu, Hanjie Zhang, Christina Maher, Jacob D. McDonald, Xiang Zhang, Shuk-Mei Ho, Beizhan Yan, Steven Chillrud, Frederica Perera, Phillip Factor, Rachel L. Miller

Get full text

Elevated VEGF Levels in Pulmonary Edema Fluid and PBMCs from Patients with Acute Hantavirus Pulmonary Syndrome by Irina Gavrilovskaya, Elena Gorbunova, Frederick Koster, Erich Mackow

Get full text

Comparative Study of Ectopic Lymphoid Aggregates in Sheep and Murine Models of Bleomycin-Induced Pulmonary Fibrosis by Udari Eshani Perera, Louise Organ, Simon G. Royce, Chrishan S. Samuel, Habtamu B. Derseh, Sasika N. V. Dewage, Emmanuel Koumoundouros, Andrew Stent, Kenneth J. Snibson

Get full text

Depression Following Thrombotic Cardiovascular Events in Elderly Medicare Beneficiaries: Risk of Morbidity and Mortality by Christopher M. Blanchette, Linda Simoni-Wastila, Fadia T. Shaya, Denise Orwig, Jason Noel, Bruce Stuart

Get full text

Machine learning insights into early mortality risks for small cell lung cancer patients post-chemotherapy by Min Liang, Min Liang, Fuyuan Luo

Get full text

Complications during chest tube drainage for iatrogenic pneumothorax by Birgitte Siem Joensen, Uffe Bodtger, Christian B. Laursen, Rob J Hallifax, Beenish Iqbal, Søren Helbo Skaarup

Get full text

Cumulative Dispensing of Oral Corticosteroids Over 12 Months in People with COPD by Burge AT, Cox NS, Dal Corso S, Jones AW, Faqih FM, Holland AE

“…Angela T Burge,1,2 Narelle S Cox,1,3 Simone Dal Corso,1 Arwel W Jones,1 Fahrayhansyah Muhammad Faqih,1 Anne E Holland1– 4 1School of Translational Medicine, Monash University, Melbourne, VIC, Australia; 2Department of Physiotherapy, Alfred Health, Melbourne, VIC, Australia; 3Institute for Breathing and Sleep, Melbourne, VIC, Australia; 4Department of Respiratory Medicine, Alfred Health, Melbourne, VIC, AustraliaCorrespondence: Angela T Burge, Respiratory Research@Alfred, Monash University, Level 6 The Alfred Centre, 99 Commercial Road, Melbourne, VIC, 3004, Australia, Email angela.burge@monash.eduPurpose: Oral corticosteroids (OCS) are recommended for the treatment of exacerbations in people with COPD; however, high cumulative lifetime doses (≥ 1000mg prednisolone-equivalent) are associated with adverse health effects. …”
Get full text

A worldwide look into long COVID-19 management: an END-COVID survey by Mattia Nigro, Claudia Valenzuela, Francisco Arancibia, Mark Cohen, David C.L. Lam, Ryan C. Maves, Barbara Rath, Steven Q. Simpson, Yuanlin Song, Sotirios Tsiodras, James D. Chalmers, Stefano Aliberti

Get full text

Promoting epithelial regeneration in chemically induced acute lung injury through Sox9-positive alveolar type 2 epithelial cells by Chao Cao, Obulkasim Memete, Yu Dun, Lin Zhang, Fuli Liu, Daikun He, Jian Zhou, Yiru Shao, Jie Shen

Get full text

What are the respiratory health research priorities in Alberta, Canada? A stakeholder consultation by Michael K Stickland, Sachin R Pendharkar, Jananee Rasiah, Joanna E MacLean, Heather Sharpe, Lisa Cerato, Darlene Derech, Lisa Guirguis, Kathleen Hayward, Tara Lohmann, Elizabeth Manafo, Janice Paskey, Mark Rimkus, Syeda Kinza Rizvi, Gerry Robinson, Brent Seefried, Zeeyaan Somani, Mindy Tindall, Harissios Vliagoftis, Kathy Hayward

“…In collaboration with project partners, the RHSCN aimed to determine the respiratory research priorities for Alberta.Design The four phases of this research prioritisation project were (1) identifying research questions from stakeholders, (2) determining which research questions had been answered in existing literature, (3) prioritising unanswered questions and (4) finalising the priorities through an inperson workshop.Setting The study occurred in Alberta, Canada over a 2-year period beginning in March 2017.Participants A total of 448 patients, clinicians and other stakeholders consented to participate in the survey.Results A total of 595 possible questions were submitted, with 343 unique questions identified. …”
Get full text

Breastfeeding and Neonatal Age Influence Neutrophil-Driven Ontogeny of Blood Cell Populations in the First Week of Human Life by Sebastiano Montante, Rym Ben-Othman, Nelly Amenyogbe, Asimenia Angelidou, Anita van den Biggelaar, Bing Cai, Yixuan Chen, Alansana Darboe, Joann Diray-Arce, Rebecca Ford, Olubukola Idoko, Amy Lee, Mandy Lo, Kerry McEnaney, Mehrnoush Malek, David Martino, Geraldine Masiria, Oludare A. Odumade, William Pomat, Casey Shannon, Kinga Smolen, The EPIC Consortium, Al Ozonoff, Peter Richmond, Scott Tebbutt, Ofer Levy, Beate Kampmann, Ryan Brinkman, Tobias Kollmann

Get full text

Computational Phenotyping of Obstructive Airway Diseases: A Systematic Review by Bashir MBA, Milani GP, De Cosmi V, Mazzocchi A, Zhang G, Basna R, Hedman L, Lindberg A, Ekerljung L, Axelsson M, Vanfleteren LEGW, Rönmark E, Backman H, Kankaanranta H, Nwaru BI

“…Muwada Bashir Awad Bashir,1 Gregorio Paolo Milani,2,3,* Valentina De Cosmi,4,5,* Alessandra Mazzocchi,3,* Guoqiang Zhang,1 Rani Basna,1 Linnea Hedman,6 Anne Lindberg,7 Linda Ekerljung,1 Malin Axelsson,8 Lowie EGW Vanfleteren,9 Eva Rönmark,6 Helena Backman,6 Hannu Kankaanranta,1,10,11 Bright I Nwaru1,12 1Krefting Research Centre, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden; 2Pediatric Unit, Foundation IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy; 3Department of Clinical Science and Community Health, University of Milan, Milan, Italy; 4Department of Food Safety, Nutrition and Veterinary Public Health, Instituto Superiore Di Sanità - Italian National Institute of Health, Roma, Italy; 5Department of Clinical Sciences and Community Health, University of Milan, Milano, Italy; 6Department of Public Health and Clinical Medicine, Section of Sustainable Health/ the OLIN Unit, Umeå University, Umeå, Sweden; 7Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden; 8Department of Care Science, Faculty of Health and Society, Malmö University, Malmö, Sweden; 9COPD Center, Sahlgrenska University Hospital, University of Gothenburg, Gothenburg, Sweden; 10Department of Respiratory Medicine, Seinäjoki Central Hospital, Seinäjoki, Finland; 11Tampere University Respiratory Research Group, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland; 12Wallenberg Centre for Molecular and Translational Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden*These authors contributed equally to this workCorrespondence: Muwada Bashir Awad Bashir, Krefting Research Centre, Institute of Medicine, University of Gothenburg, P.O. …”
Get full text

Diagnosis, screening, and follow-up of patients with familial interstitial lung disease: Results from an international survey by Emil Vilstrup Moen, Thomas Skovhus Prior, Michael Kreuter, Wim A. Wuyts, Maria Molina-Molina, Marlies Wijsenbeek, Antonió Morais, Argyrios Tzouvelekis, Christopher J. Ryerson, Fabian Caro, Ivette Buendia-Roldan, Jesper M. Magnusson, Joyce S. Lee, Julie Morisett, Justin M. Oldham, Lauren K. Troy, Manuela Funke-Chambour, Maria Laura Alberti, Raphael Borie, Simon L. F. Walsh, Sujeet Rajan, Yasuhiro Kondoh, Yet H Khor, Elisabeth Bendstrup

Get full text