Adverse outcome pathway-based assessment of pulmonary toxicity from the in vivo mixture of biocides dinotefuran and cetylpyridinium chloride by Yoon Cho, Mi-Kyung Song, Dong Im Kim, Min-Seok Kim, Kyuhong Lee

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Diagnostic Accuracy of Shear Wave Elastography in Predicting Malignant Origins of Pleural Effusions in Emergency Departments by Rune Wiig Nielsen, Casper Falster, Stefan Posth, Niels Jacobsen, August Emil Licht, Rahul Bhatnagar, Christian Borbjerg Laursen

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The Ability of Secretory Leukocyte Protease Inhibitor to Inhibit Apoptosis in Monocytes Is Independent of Its Antiprotease Activity by Niamh McGarry, Catherine M. Greene, Noel G. McElvaney, Sinéad Weldon, Clifford C. Taggart

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Update on the Canadian Institutes of Health Research: Where Will Respiratory Health Research Fit in? by Malcolm King

“…The centre of attention has, of course, been the soon-to-be-established Canadian Institutes of Health Research (CIHR) and our Society's efforts to establish a position for respiratory research withing this new organization.…”
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Research priorities for preterm lung health research across the lifespan: a community priority setting partnership by Anne McKenzie, Shannon J Simpson, Naomi R Hemy, Amber Bates, Belinda Frank

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Editorial: Psychosocial issues and interventions in pulmonary rehabilitation by Ingeborg Farver-Vestergaard, Ingeborg Farver-Vestergaard, Eleonora Volpato, Eleonora Volpato, Eleonora Volpato, Henrik Hansen, Henrik Hansen, Henrik Hansen, Liz Steed

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Prenatal and Postnatal Polycyclic Aromatic Hydrocarbon Exposure, Airway Hyperreactivity, and Beta-2 Adrenergic Receptor Function in Sensitized Mouse Offspring by Sophie Chu, Hanjie Zhang, Christina Maher, Jacob D. McDonald, Xiang Zhang, Shuk-Mei Ho, Beizhan Yan, Steven Chillrud, Frederica Perera, Phillip Factor, Rachel L. Miller

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Comparative Study of Ectopic Lymphoid Aggregates in Sheep and Murine Models of Bleomycin-Induced Pulmonary Fibrosis by Udari Eshani Perera, Louise Organ, Simon G. Royce, Chrishan S. Samuel, Habtamu B. Derseh, Sasika N. V. Dewage, Emmanuel Koumoundouros, Andrew Stent, Kenneth J. Snibson

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Depression Following Thrombotic Cardiovascular Events in Elderly Medicare Beneficiaries: Risk of Morbidity and Mortality by Christopher M. Blanchette, Linda Simoni-Wastila, Fadia T. Shaya, Denise Orwig, Jason Noel, Bruce Stuart

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Machine learning insights into early mortality risks for small cell lung cancer patients post-chemotherapy by Min Liang, Min Liang, Fuyuan Luo

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Complications during chest tube drainage for iatrogenic pneumothorax by Birgitte Siem Joensen, Uffe Bodtger, Christian B. Laursen, Rob J Hallifax, Beenish Iqbal, Søren Helbo Skaarup

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Cumulative Dispensing of Oral Corticosteroids Over 12 Months in People with COPD by Burge AT, Cox NS, Dal Corso S, Jones AW, Faqih FM, Holland AE

“…Angela T Burge,1,2 Narelle S Cox,1,3 Simone Dal Corso,1 Arwel W Jones,1 Fahrayhansyah Muhammad Faqih,1 Anne E Holland1– 4 1School of Translational Medicine, Monash University, Melbourne, VIC, Australia; 2Department of Physiotherapy, Alfred Health, Melbourne, VIC, Australia; 3Institute for Breathing and Sleep, Melbourne, VIC, Australia; 4Department of Respiratory Medicine, Alfred Health, Melbourne, VIC, AustraliaCorrespondence: Angela T Burge, Respiratory Research@Alfred, Monash University, Level 6 The Alfred Centre, 99 Commercial Road, Melbourne, VIC, 3004, Australia, Email angela.burge@monash.eduPurpose: Oral corticosteroids (OCS) are recommended for the treatment of exacerbations in people with COPD; however, high cumulative lifetime doses (≥ 1000mg prednisolone-equivalent) are associated with adverse health effects. …”
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Promoting epithelial regeneration in chemically induced acute lung injury through Sox9-positive alveolar type 2 epithelial cells by Chao Cao, Obulkasim Memete, Yu Dun, Lin Zhang, Fuli Liu, Daikun He, Jian Zhou, Yiru Shao, Jie Shen

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What are the respiratory health research priorities in Alberta, Canada? A stakeholder consultation by Michael K Stickland, Sachin R Pendharkar, Jananee Rasiah, Joanna E MacLean, Heather Sharpe, Lisa Cerato, Darlene Derech, Lisa Guirguis, Kathleen Hayward, Tara Lohmann, Elizabeth Manafo, Janice Paskey, Mark Rimkus, Syeda Kinza Rizvi, Gerry Robinson, Brent Seefried, Zeeyaan Somani, Mindy Tindall, Harissios Vliagoftis, Kathy Hayward

“…In collaboration with project partners, the RHSCN aimed to determine the respiratory research priorities for Alberta.Design The four phases of this research prioritisation project were (1) identifying research questions from stakeholders, (2) determining which research questions had been answered in existing literature, (3) prioritising unanswered questions and (4) finalising the priorities through an inperson workshop.Setting The study occurred in Alberta, Canada over a 2-year period beginning in March 2017.Participants A total of 448 patients, clinicians and other stakeholders consented to participate in the survey.Results A total of 595 possible questions were submitted, with 343 unique questions identified. …”
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Breastfeeding and Neonatal Age Influence Neutrophil-Driven Ontogeny of Blood Cell Populations in the First Week of Human Life by Sebastiano Montante, Rym Ben-Othman, Nelly Amenyogbe, Asimenia Angelidou, Anita van den Biggelaar, Bing Cai, Yixuan Chen, Alansana Darboe, Joann Diray-Arce, Rebecca Ford, Olubukola Idoko, Amy Lee, Mandy Lo, Kerry McEnaney, Mehrnoush Malek, David Martino, Geraldine Masiria, Oludare A. Odumade, William Pomat, Casey Shannon, Kinga Smolen, The EPIC Consortium, Al Ozonoff, Peter Richmond, Scott Tebbutt, Ofer Levy, Beate Kampmann, Ryan Brinkman, Tobias Kollmann

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Computational Phenotyping of Obstructive Airway Diseases: A Systematic Review by Bashir MBA, Milani GP, De Cosmi V, Mazzocchi A, Zhang G, Basna R, Hedman L, Lindberg A, Ekerljung L, Axelsson M, Vanfleteren LEGW, Rönmark E, Backman H, Kankaanranta H, Nwaru BI

“…Muwada Bashir Awad Bashir,1 Gregorio Paolo Milani,2,3,* Valentina De Cosmi,4,5,* Alessandra Mazzocchi,3,* Guoqiang Zhang,1 Rani Basna,1 Linnea Hedman,6 Anne Lindberg,7 Linda Ekerljung,1 Malin Axelsson,8 Lowie EGW Vanfleteren,9 Eva Rönmark,6 Helena Backman,6 Hannu Kankaanranta,1,10,11 Bright I Nwaru1,12 1Krefting Research Centre, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden; 2Pediatric Unit, Foundation IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy; 3Department of Clinical Science and Community Health, University of Milan, Milan, Italy; 4Department of Food Safety, Nutrition and Veterinary Public Health, Instituto Superiore Di Sanità - Italian National Institute of Health, Roma, Italy; 5Department of Clinical Sciences and Community Health, University of Milan, Milano, Italy; 6Department of Public Health and Clinical Medicine, Section of Sustainable Health/ the OLIN Unit, Umeå University, Umeå, Sweden; 7Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden; 8Department of Care Science, Faculty of Health and Society, Malmö University, Malmö, Sweden; 9COPD Center, Sahlgrenska University Hospital, University of Gothenburg, Gothenburg, Sweden; 10Department of Respiratory Medicine, Seinäjoki Central Hospital, Seinäjoki, Finland; 11Tampere University Respiratory Research Group, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland; 12Wallenberg Centre for Molecular and Translational Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden*These authors contributed equally to this workCorrespondence: Muwada Bashir Awad Bashir, Krefting Research Centre, Institute of Medicine, University of Gothenburg, P.O. …”
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Diagnosis, screening, and follow-up of patients with familial interstitial lung disease: Results from an international survey by Emil Vilstrup Moen, Thomas Skovhus Prior, Michael Kreuter, Wim A. Wuyts, Maria Molina-Molina, Marlies Wijsenbeek, Antonió Morais, Argyrios Tzouvelekis, Christopher J. Ryerson, Fabian Caro, Ivette Buendia-Roldan, Jesper M. Magnusson, Joyce S. Lee, Julie Morisett, Justin M. Oldham, Lauren K. Troy, Manuela Funke-Chambour, Maria Laura Alberti, Raphael Borie, Simon L. F. Walsh, Sujeet Rajan, Yasuhiro Kondoh, Yet H Khor, Elisabeth Bendstrup

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