Coexistence of Anti-GAD and Anti-GABAAR Antibodies in an Autoimmune Encephalitis Patient: A Case Report by Lu X, Wu H, Tan Y, Mao X

“…Xiaoyan Lu,* Hangfei Wu,* Yuhao Tan, Xiaowei Mao Department of Neurology, Changhai Hospital, Naval Medical University (Second Military Medical University), Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiaowei Mao, Department of Neurology, Changhai Hospital, Naval Medical University (Second Military Medical University), Shanghai, People’s Republic of China, Email xiaoweimaoamtf@163.comBackground: Coexistence of autoimmune encephalitis (AE) with multiple autoantibodies is of particular concern because overlying antibodies may cause variation of clinical manifestations. …”
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A new conceptual model for seed germination and seedling tillering of winter wheat in the field by Jinping Chen, Peter A. Whalley, Zhongyang Li, Xiaoxian Zhang, Malcolm J. Hawkesford, W. Richard Whalley

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The Eruptive Duality of a Filament on 2023 April 21 by Yue Fang, Jun Zhang

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Advancing CO2++ Modeling in the Martian Dayside Ionosphere: Insights from Natural Lifetime Analysis by Long Cheng, Erik Vigren, Moa Persson, Hao Gu, Jun Cui

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Advances in Ultrasound-Targeted Microbubble Destruction (UTMD) for Breast Cancer Therapy by Wu Y, Liu Y, Wu H, Tong M, Du L, Ren S, Che Y

“…Yunfeng Wu,1 Yuxi Liu,2 Han Wu,1 Mengying Tong,1 Linyao Du,1 Shuangsong Ren,1 Ying Che1 1Department of Ultrasound, The First Affiliated Hospital of Dalian Medical University, Liaoning, Dalian, People’s Republic of China; 2Department of Ultrasound, Shandong Second Medical University Affiliated Hospital, Shan Dong, Weifang, People’s Republic of ChinaCorrespondence: Ying Che, Email yche1964@163.comAbstract: Breast cancer is one of the most common types of cancer in women worldwide and is a leading cause of cancer deaths among women. …”
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Sculpturing sound fields with the real-space structural topology of acoustic cavities by Qing Tong, Shubo Wang

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Inflammatory Indices and MAFLD Prevalence in Hypertensive Patients: A Large-Scale Cross-Sectional Analysis from China by Shen D, Cai X, Hu J, Song S, Zhu Q, Ma H, Zhang Y, Ma R, Zhou P, Yang W, Hong J, Zhang D, Li N

“…Di Shen,1,* Xintian Cai,2,* Junli Hu,2 Shuaiwei Song,1 Qing Zhu,2 Huimin Ma,2 Yingying Zhang,2 Rui Ma,2 Pan Zhou,2 Wenbo Yang,2 Jing Hong,2 Delian Zhang,2 Nanfang Li2 1Graduate School, Xinjiang Medical University, Urumqi, Xinjiang, People’s Republic of China; 2Hypertension Center of People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hypertension Institute, NHC Key Laboratory of Hypertension Clinical Research, Key Laboratory of Xinjiang Uygur Autonomous Region, Hypertension Research Laboratory, Xinjiang Clinical Medical Research Center for Hypertension (Cardio-Cerebrovascular) Diseases, Urumqi, Xinjiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Nanfang Li, Hypertension Center of People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hypertension Institute, NHC Key Laboratory of Hypertension Clinical Research, Key Laboratory of Xinjiang Uygur Autonomous Region “Hypertension Research Laboratory”, Xinjiang Clinical Medical Research Center for Hypertension (Cardio-Cerebrovascular) Diseases, No. 91 Tianchi Road, Urumuqi, Xinjiang, 830001, People’s Republic of China, Tel +86 8564818, Email lnanfang2016@sina.comObjective: Hypertension development and progression are largely influenced by inflammation, which plays a critical role by activating the immune system and causing damage to the vascular endothelium. …”
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Long-Term Analysis of Recurrence Beyond Milan Criteria Following Ablation of Solitary Early-Stage Hepatocellular Carcinoma ≤3 cm in Potentially Transplantable Patients: A Over 1... by Chen S, Qi H, Tan H, Cao F, Xie L, Huang T, Wu Y, Wen C, Wang Y, Shen L, Fan W

“…Shuanggang Chen,1,2,* Han Qi,1,2,* Hongtong Tan,1,2,* Fei Cao,1,2 Lin Xie,1,2 Tao Huang,1,2 Ying Wu,3 Chunyong Wen,1,2 Yujia Wang,1,2 Lujun Shen,1,2 Weijun Fan1,2 1Department of Minimally Invasive Interventional Therapy, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, People’s Republic of China; 2State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for cancer, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, People’s Republic of China; 3Department of Interventional Therapy, Shenzhen second People’s Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, 518035, People’s Republic of China*These authors contributed equally to this workCorrespondence: Weijun Fan, Email fanwj@sysucc.org.cn; Lujun Shen, Email shenlj@sysucc.org.cnBackground: Salvage liver transplantation is promising for hepatocellular carcinoma(HCC) recurrence post-ablation but is significantly affected by recurrence beyond Milan Criteria (RBM).Materials and Methods: A retrospective cohort study of potentially transplantable HCC patients undergoing ablation between 2007 and 2017 assessed median time to recurrence beyond Milan Criteria(TRBM) via Kaplan-Meier curves and predictive capacity of recurrence and RBM for overall survival(OS) via Receiver Operating Characteristic Curves, and identified independent risk factors for TRBM and RBM via Cox and binary logistic regression models.Results: We enrolled 191 potentially transplantable patients with early-stage HBV-related HCC ≤ 3 cm who underwent ablation. …”
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Impact of Self-Management Clustered Care on Psychological and Birth Outcomes in Gestational Diabetes by Tang S, Wang S, Wu J, Hu S, Lu T, Zhu M, Li J, Xue F

“…Shuting Tang,1,* Song Wang,1,* Jinyan Wu,1 Shoudi Hu,1 Tingting Lu,2 Minli Zhu,2 Jinzhi Li,1 Fang Xue1 1School of Nursing, Bengbu Medical University, Bengbu, Anhui, People’s Republic of China; 2Maternity Ward, the First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fang Xue, School of Nursing, Bengbu Medical University, No. 2600 Donghai Avenue, Bengbu, Anhui, People’s Republic of China, Email 0700036@bbmu.edu.cnPurposes: To investigate the effects of a self-management-cluster-based pregnancy care model (SMB-CPCM) on the psychological status and delivery outcomes of pregnant women with gestational diabetes mellitus (GDM).Patients and Methods: A total of 120 pregnant women with GDM who had been filed and had regular obstetric examinations in a tertiary-level hospital in Bengbu City between 1 April 2023 and 1 April 2024 were included in the study using the convenience sampling method. …”
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Fabrication of Nano-Silver Composite Using Amomum longiligulare Fruit Polysaccharides and Their Biological Activities by Lian Y, Ma N, Cheng Q, Luo M, Xu Z, He F, Zhou X, Zhang Y, Jin D, Kong Y, Wang Y, Wei N

“…Yong Lian,1,* Ning Ma,2,* Qianying Cheng,1,* Mingquan Luo,1 Zhen Xu,1 Fei He,1 Xiaomei Zhou,1 Ying Zhang,1 Dejun Jin,1 Yidan Kong,1 Yong Wang,1 Na Wei1 1Hainan Provincial Key Laboratory of R&D on Tropical Herbs, Engineering Research Center of Tropical Medicine Innovation and Transformation of Ministry of Education, International Joint Research Center of Human-Machine Intelligent Collaborative for Tumor Precision Diagnosis and Treatment of Hainan Province, School of Pharmacy, Hainan Medical University, Haikou, 571199, People’s Republic of China; 2Reproductive Medical Center, Hainan Women and Children’s Medical Center, Haikou, Hainan Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Na Wei; Yong Wang, Hainan Provincial Key Laboratory of R&D on Tropical Herbs, School of Pharmacy, Hainan Medical University, Haikou, 571199, People’s Republic of China, Email weina-0613@163.com; wangyong1982_2004@163.comPurpose: Study aims to optimize the synthesis conditions for silver nanoparticle composites [ALP(D)-AgNPs] using a rapid and environmentally friendly method and investigate the antioxidant, antibacterial, and anticancer activities of the fabricated composite.Methods: The polysaccharide component ALP-D was extracted and purified from the fruits of Amomum longiligulare and subsequently used for further experiments. …”
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Intervening Non-Small-Cell Lung Cancer Progression by Cell Membrane Coated Platycodin D via Regulating Hsa-miR-1246/FUT9/GSK3β Pathway by Zheng S, Xie Z, Zhou Z, Wang S, Xin Y, Lin J, Cheng K, Lu T, Qi R, Guo Y

“…Shuyu Zheng,1,2 Zejuan Xie,1 Ziao Zhou,1 Shanshan Wang,1 Yanlin Xin,1 Jiamin Lin,1 Keyu Cheng,1 Tianming Lu,1 Ruogu Qi,1 Yuanyuan Guo1 1Department of Biochemistry and Molecular Biology, School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, People’s Republic of China; 2Department of Neurosurgery, The Second Affiliated Hospital, Zhejiang University, Hangzhou, Zhejiang Province, 310009, People’s Republic of ChinaCorrespondence: Ruogu Qi; Yuanyuan Guo, Department of Biochemistry and Molecular Biology, School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, People’s Republic of China, Email rqi@njucm.edu.cn; guoyy@njucm.edu.cnPurpose: Metastatic non-small cell lung cancer (NSCLC) remains a global health threat, with patients facing inevitable disease progression despite standard-of-care therapy. …”
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Remimazolam Suppresses Oxidative Stress and Apoptosis in Cerebral Ischemia/Reperfusion Injury by Regulating AKT/GSK-3β/NRF2 Pathway by Duan M, Yu N, Liu J, Zhao Y, Zhang J, Song S, Wang S

“…Mei Duan,1,* Ning Yu,1,* Jia Liu,1 Yang Zhao,1 Jing Zhang,1 Siyi Song,2 Shilei Wang1 1Department of Anesthesiology, The Affiliated Hospital of Qingdao University, Qingdao, People’s Republic of China; 2Department of Anesthesia and Perioperative Medicine, The First Affiliated Hospital of Shandong First Medical University, Jinan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Shilei Wang, Department of Anesthesiology, The Affiliated Hospital of Qingdao University, Qingdao, People’s Republic of China, Tel +86 186 6180 6773, Email wshlei@aliyun.comIntroduction: The mechanism of remimazolam, a benzodiazepine that activates γ-aminobutyric acid a (GABAa) receptors, in cerebral ischemia/reperfusion (I/R) injury is not well understood. …”
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Development and Validation of the Systemic Inflammatory Response Index-Based Nomogram for Predicting Short-Term Adverse Events in Patients With Acute Uncomplicated Type B Aortic In... by Wang Y, Wu X, Wang Y, Zhang Z, Liu X, Sun D, Liu X, Zhou T, Wang X

“…Yasong Wang,1,2 Xuan Wu,2 Yue Wang,2 Zhiqiang Zhang,2 Xuanze Liu,2 Dongyuan Sun,2 Xue Liu,2 Tienan Zhou,2 Xiaozeng Wang2 1Graduate School of Dalian Medical University, Dalian Medical University, Dalian, 116044, People’s Republic of China; 2State Key Laboratory of Frigid Zone Cardiovascular Diseases, Cardiovascular Research Institute and Department of Cardiology, General Hospital of Northern Theater Command, Shenyang, 110016, People’s Republic of ChinaCorrespondence: Xiaozeng Wang, Department of Cardiology, Institute of Cardiovascular Research, General Hospital of Northern Theater Command, Shenhe District, Shenyang, Liaoning, 110016, People’s Republic of China, Tel +86-24-28897241, Email wxiaozeng@163.comPurpose: This study aims to develop and validate a nomogram based on the Systemic Inflammatory Response Index (SIRI) to predict short-term aortic-related adverse events (ARAEs) in patients with acute uncomplicated Type B intramural hematoma (IMH).Patients and methods: We retrospectively analyzed 332 patients diagnosed with acute uncomplicated Type B IMH between April 2018 and April 2024. …”
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Non-Luminal Disease Score for Everolimus in Patients with Hormone Receptor‑positive and Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: A Mult... by Tan Y, Jiang H, Tian X, Ma F, Wang J, Zhang P, Xu B, Fan Y, Zhao W

“…Yujing Tan,1,* Hanfang Jiang,2,* Xinzhu Tian,1,* Fei Ma,1 Jiayu Wang,1 Pin Zhang,1 Binghe Xu,1 Ying Fan,1 Weihong Zhao3 1Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100021, People’s Republic of China; 2Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Breast Oncology, Peking University Cancer Hospital & Institute, Beijing, 100142, People’s Republic of China; 3Department of Medical Oncology, Chinese PLA General Hospital, Beijing, 100853, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ying Fan; Weihong Zhao, Email fanying@cicams.ac.cn; zhaowh0818@163.comPurpose: This study aims to explore the role of the non-luminal disease score (NOLUS) for everolimus in patients with hormone receptor-positive and human epidermal growth factor receptor 2-negative (HR+/HER2-) advanced breast cancer (ABC).Methods: NOLUS has previously been established as an algorithm: NOLUS (0– 100) = − 0.45 × ER(%) − 0.28 × PR(%) + 0.27 × Ki67(%) + 73. …”
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CircPRMT5, a Potential Salivary Biomarker, Facilitates the Progression of Head and Neck Squamous Cell Carcinoma via the IGF2BP3-SERPINE1 Pathway by Jiang S, Ou L, Wang Y, Su K, Chen Z, He L, Xu X, Cheng B, Xia J, Fan Z

“…Siqi Jiang,1,2 Linlin Ou,1,2 Yueqi Wang,1,2 Kai Su,1,2 Zhipei Chen,1,2 Lihong He,1,2 Xun Xu,1,2 Bin Cheng,1,2 Juan Xia,1,2 Zhaona Fan1,2 1Hospital of Stomatology, Sun Yat-sen University, Guangzhou, People’s Republic of China; 2Guangdong Provincial Key Laboratory of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, People’s Republic of ChinaCorrespondence: Zhaona Fan; Juan Xia, Hospital of Stomatology, Sun Yat-sen University, No. 56 Lingyuanxi Road, Guangzhou, Guangdong, 510055, People’s Republic of China, Tel +86 20 87394123 ; +86 20 83741891, Fax +86 20 83822807, Email fanzhn3@mail.sysu.edu.cn; xiajuan@mail.sysu.edu.cnPurpose: Circular RNAs (circRNAs) are associated with the progression of tumors and hold promise as potential biomarkers for liquid biopsy. …”
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Adjusting (AlNi)/(FeCr) ratio to tailor microstructure and properties of A2-B2 dual-phase (AlNi)x(FeCr)100-x medium-entropy alloys by Guijiang Diao, Mingyu Wu, Anqiang He, Zhen Xu, Dhruv Bajaj, Daolun Chen, Ranran Fang, Anatoliy Vorobyev, Q.Y. Li, Dongyang Li

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Novel Clinical Insights into the Pathogenesis of Posttraumatic Elbow Stiffness: An Expression Profile Analysis of Contracted Joint Capsule in Human by Liu N, Dong J, Li L, Xu J, Yang C, Yu Z, Liu F

“…Nan Liu,1 Jinlei Dong,1 Lianxin Li,1 Jiajun Xu,1 Changhao Yang,1 Zhanchuan Yu,2 Fanxiao Liu1 1Department of Shandong Trauma Center, Shandong Provincial Hospital affiliated to Shandong First Medical University, Jinan, Shandong, 250014, People’s Republic of China; 2Department of Shandong Trauma Center, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250014, People’s Republic of ChinaCorrespondence: Fanxiao Liu, Department of Shandong Trauma Center, Shandong Provincial Hospital affiliated to Shandong First Medical University, Jingshi str. 9677, Jinan, Shandong, 250014, People’s Republic of China, Tel/Fax +86-0531-68773195, Email woshi631@126.com; liufanxiao@sdfmu.edu.cnBackground: Posttraumatic elbow stiffness is a complex complication with two characteristics of capsular contracture and heterotopic ossification. …”
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Interleukin-1 Receptor-Associated Kinase-3 Aggravates Neuroinflammatory Injury After Intracerebral Hemorrhage via Activation NF-κB/IL-17A Pathway in Mice by Wang J, Li Y, Tan C, Shao J, Tang W, Kong Q, Sheng W, Ding Z, Li F, Piao J, Lv D, Hu L, Wang Q, Jiang X

“…Jun Wang,1,* Yulong Li,1,* Chunyu Tan,1,* Jinlian Shao,1 Weitai Tang,2 Quan Kong,3 Wenqianjun Sheng,1 Zhiquan Ding,1 Feng Li,1 Jifeng Piao,1 Dingyi Lv,1 Libin Hu,1 Qinghua Wang,1 Xiaodan Jiang1 1Neuromedicine Center, The National Key Clinical Specialty, The Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, The Neurosurgery Institute of Guangdong Province, Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, People’s Republic of China; 2Department of Neurosurgery, The People’s Hospital of Luoding & Affiliated Luoding Hospital of Guangdong Medical University, Luoding, 527200, People’s Republic of China; 3Neurosurgery Department of Zengcheng Campus, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qinghua Wang; Xiaodan Jiang, Email wqh1123@126.com; jiangxiao_dan@163.comBackground: Neuroinflammatory reactions are crucial factors in secondary brain damage following intracerebral hemorrhage (ICH). …”
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Rat Model of Cystic Neutrophilic Granulomatous Mastitis by Corynebacterium Kroppenstedtii by Wang M, Zeng Y, Liu M, Zhang D, Zhao D, Wang J, Liu Y, Zhao W

“…Mengjie Wang,1,2 Yifei Zeng,1,2 Min Liu,1 Dongxiao Zhang,1 Di Zhao,1,2 Junyue Wang,1,2 Yongxin Liu,1,2 Wenjie Zhao1 1Department of Galactophore, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, 100010, People’s Republic of China; 2School of Clinical Medicine, Beijing University of Chinese Medicine, Beijing, 100029, People’s Republic of ChinaCorrespondence: Dongxiao Zhang, Department of Galactophore, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, No. 23, Art Museum Back Street, Dongcheng District, Beijing, 100010, People’s Republic of China, Tel +86 13811077684, Email tzdx_thinking@126.comBackground: Cystic neutrophilic granulomatous mastitis (CNGM) poses a significant threat to the physical and mental health of women due to its increasing incidence, complex clinical manifestations. …”
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The Influence of Depression, Anxiety, and Stress on Ageism Among Undergraduates: Mediating Roles of Life Satisfaction, Gratitude, and Prosociality by Chen S, Wan Z

“…Se Chen,1 Zhonglei Wan2 1School of International Education, Jiangxi Science and Technology Normal University, Nanchang, Jiangxi, People’s Republic of China; 2Department of General Education, Jiangxi Youth Vocational College, Nanchang, Jiangxi, People’s Republic of ChinaCorrespondence: Se Chen, Jiangxi Science and Technology Normal University, 589 Xuefu Avenue, Nanchang, Jiangxi Province, 330038, People’s Republic of China, Tel +0086 – 18679059130, Email chense063@foxmail.comBackground: The rapid growth of the global aging population highlights the need to address ageism and promote social inclusiveness. …”
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