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Corticosteroid Phobia: A Key Barrier to Treatment in Young Women with Idiopathic Granulomatous Mastitis
Published 2025-01-01“…Weiyi Lin,1,2,* Qiuzhou Wang,2,* Jia Liu,1,2 Qiuwen Tan1,2 1Division of Breast Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu City, Sichuan Province, People’s Republic of China; 2Breast Center, West China Hospital, Sichuan University, Chengdu City, Sichuan Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qiuwen Tan, Division of Breast Surgery, Department of General Surgery, West China Hospital, Sichuan University, No. 37 Guo Xue Alley, Chengdu City, Sichuan Province, 610041, People’s Republic of China, Email hxtanqiuwen@163.comPurpose: Corticosteroids are recommended as a first-line treatment for idiopathic granulomatous mastitis (IGM), a disease that usually occurs in young women. …”
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1142
Changes in and Potential Mechanisms of Circulating IgA+CD27-Class-Switched Memory B Cells in Patients With Allergic Rhinitis
Published 2025-01-01“…Han Zheng,1,* Shan Xu,1,* Rui Yang,1,* Wo-Er Jiao,1 Yue-Long Qiao,1,2 Jia-Yu Liu,1 Hui-Ming Fan,1 Yan-Ting Zhou,1 Hai-Feng Ni,3 Jin Chen,1 Yu-Qin Deng,1 Shi-Ming Chen1 1Department of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, People’s Republic of China; 2Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland; 3Department of Otolaryngology-Head and Neck Surgery, Zhejiang Hospital, Hangzhou, Zhejiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yu-Qin Deng; Shi-Ming Chen, Department of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, People’s Republic of China, Email bamboo0723@126.com; shimingchen0468@163.comBackground: The role of memory B cells and their subgroups in allergic rhinitis (AR) and allergen immunotherapy (AIT) remains unclear. …”
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1143
Correlation Between Inflammatory Markers and Pathogenic Bacteria in Children’s Winter Respiratory Infections in Xinjiang
Published 2025-01-01“…Lixia Wang,1,* Wei Wang,2,* Jian Wang,1 Ling Zhu,1 Jianjiang Luo1 1Department of Respiratory and Critical Care Medical Department Infectious Diseases Ward, The Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University, Urumqi, Xinjiang, People’s Republic of China; 2Department of Respiratory and Critical Care Medicine, Affiliated Traditional Chinese Medicine Hospital of Xinjiang Medical University, Urumqi, Xinjiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jianjiang Luo, Department of Respiratory and Critical Care Medical Department infectious diseases Ward, The Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University, No. 116 Huanghe Road, Shayibake District, Urumqi, Xinjiang, People’s Republic of China, Tel +86013999946655, Email ljj.781201@163.comBackground: This study examines the distribution characteristics of pathogenic bacteria in respiratory infections and their relationship with inflammatory markers to guide clinical drug use.Methods: We selected 120 patients with lower respiratory tract infection in the electronic medical record system of Xinjiang Provincial People’s Hospital from March 2019 to March 2023 for a case-control study. …”
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Evaluation of the Effectiveness of Standard Precaution Training on Disposition of Occupational Blood Exposure Among Healthcare Trainees: A Pre-Post Intervention Study
Published 2025-01-01“…Xing Zhang,1 Hongwei Li,2 Ning Li,1 Yusen Li,1 Li Kong,1 Min Zhang,1 Peng Wang,1 Yonghui Ma,1 Leiping Ni,2 Lili Liu,1 Xiujuan Meng1 1Healthcare-Associated Infection Control Department, Affiliated Hospital of Jining Medical University, Jining, Shandong, People’s Republic of China; 2Medical Education Center, Affiliated Hospital of Jining Medical University, Jining, Shandong, People’s Republic of ChinaCorrespondence: Xiujuan Meng, Healthcare-associated infection control department, Affiliated Hospital of Jining Medical University, Jining, Shandong, People’s Republic of China, Tel +86 537 2903180, Fax +86 537 2213030, Email mxj0324@163.comIntroduction: Blood-borne occupational exposure (OBE) is one of the major public health problem for healthcare workers globally. …”
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1146
Pharmacokinetics and Bioequivalence of Two Fixed-Dose Combination Tablets of Valsartan/Amlodipine (80/5 Mg) in Healthy Chinese Subjects
Published 2025-01-01“…Mengli Tian,1 Jinlong Huang,2 Yingrong Chen,1 Qiuyue Jin,1 Hong Jiang,2 Cunyuan Shi,2 Jue Mei,1 Min Xu,1 Xiang Yu,1 Shuixin Yang1 1Clinical Trial Center, Huzhou Central Hospital, Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou, 313000, People’s Republic of China; 2Zhejiang Jianfeng Pharmaceutical Co Ltd., Jinhua, 321025, People’s Republic of ChinaCorrespondence: Shuixin Yang, Clinical Trial Center, Huzhou Central Hospital, Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, 1558, North Third Ring Road, Huzhou, 313000, People’s Republic of China, Tel +86-0572-2978254, Email ysx@hzhospital.comPurpose: The study aimed to investigate the pharmacokinetics and bioequivalence of coformulations of valsartan and amlodipine in healthy Chinese subjects under both fasting and fed conditions.Methods: The research was conducted under both fasting and fed studies and employed a single-center, randomized, open-label, single-dose, three-period design with partial-repeat and crossover elements. …”
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1147
The Prognostic Significance of the CALLY Index in Ampullary Carcinoma: An Inflammation-Nutrition Retrospective Analysis
Published 2025-01-01“…Pu Xi,1,* Guizhong Huang,1,* Kewei Huang,2,* Dailei Qin,1 Zehui Yao,1 Lingmin Jiang,1 Qi Zhu,1 Chaobin He1 1Department of Pancreatobiliary Surgery, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, People’s Republic of China; 2State Key Laboratory of Oncology in South China, Department of Clinical Laboratory, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chaobin He, Department of Pancreatobiliary Surgery, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, 651 Dongfeng Road E, Guangzhou, Guangdong, 510060, People’s Republic of China, Email hechb@sysucc.org.cnBackground: As a novel inflammatory-nutritional biomarker, the C-reactive protein–albumin–lymphocyte (CALLY) index has demonstrated significant prognostic value in various malignancies. …”
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1148
Tanshinone I Ameliorates Psoriasis-Like Dermatitis by Suppressing Inflammation and Regulating Keratinocyte Differentiation
Published 2025-01-01“…Qiao Wang,1,* Xin Luo,1,* Yuwen Su,1 Yi Jin,1 Qiqi Kuang,1 Siying Li,1 Weiyun Shen,2 Yanshan Zhu1 1Department of Dermatology, Second Xiangya Hospital, Hunan Key Laboratory of Medical Epigenomics, Clinical Medical Research Center of Major Skin Diseases and Skin Health of Hunan Province, Central South University, Changsha, Hunan, People’s Republic of China; 2Department of Anesthesiology, Second Xiangya Hospital, Anesthesiology Research Institute of Central South University, Changsha, Hunan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xin Luo; Yanshan Zhu, Department of Dermatology, Second Xiangya Hospital, Hunan Key Laboratory of Medical Epigenomics, Clinical Medical Research Center of Major Skin Diseases and Skin Health of Hunan Province, Central South University, 139 Renmin Middle Road, Changsha, Hunan, People’s Republic of China, Email 248201037@csu.edu.cn; 218202091@csu.edu.cnBackground: Psoriasis is an immune-related inflammatory systemic condition characterized by dysregulated keratinocyte proliferation and chronic inflammation. …”
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1149
Association of Depression with Age at Natural Menopause: A Cross-Sectional Analysis with NHANES Data
Published 2025-01-01“…Shuaiqi An,1,* Shiyan Ren,1,* Jiawen Ma,1 Yizhou Zhang1,2 1School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, People’s Republic of China; 2Zhejiang Famous Chinese Medicine Clinic, the Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yizhou Zhang, School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, People’s Republic of China, Email zhangyizhou2005@126.comPurpose: To evaluate the association between depression and age of natural menopause in American women.Patients and Methods: This cross-sectional study utilized eight cycles of the National Health and Nutrition Examination Survey (NHANES) conducted from 2005 to 2023. …”
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Phage vB_Kpn_HF0522: Isolation, Characterization, and Therapeutic Potential in Combatting K1 Klebsiella pneumoniae Infections
Published 2025-02-01“…Tao Yan,1,2 Qiuyan Wang,2 Chengcheng Ma,2 Xuan Teng,2 Zhen Gong,2 Wenwen Chu,2 Qiang Zhou,2 Zhou Liu1 1Department of Clinical Laboratory Center, Anhui Chest Hospital, Hefei, 230031, People’s Republic of China; 2Department of Clinical Laboratory, the Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, People’s Republic of ChinaCorrespondence: Zhou Liu, Department of Clinical Laboratory Center, Anhui Chest Hospital, Hefei, People’s Republic of China, Email liuzhou0112@ahmu.edu.cnPurpose: Klebsiella pneumoniae is a globally prevalent pathogen responsible for severe hospital- and community-acquired infections, and presents significant challenges for clinical management. …”
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1151
The Mediating Role of Cognitive Reappraisal on Bedtime Procrastination and Sleep Quality in Higher Educational Context: A Three-Wave Longitudinal Study
Published 2025-01-01“…Yuan Zhang,1 Shazia Rehman,2 Abdullah Addas,3,4 Mehmood Ahmad,5 Ayesha Khan6 1College of Art, Nanyang Vocational College of Agriculture, Nan Yang, Henan, 47300, People’s Republic of China; 2Department of Psychiatry, National Clinical Research Center for Mental Disorders, and National Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, People’s Republic of China; 3Department of Civil Engineering, College of Engineering, Prince Sattam Bin Abdulaziz University, Al-Kharj, 11942, Saudi Arabia; 4Landscape Architecture Department, Faculty of Architecture and Planning, King Abdulaziz University, Jeddah, 21589, Saudi Arabia; 5Department of Pharmacology and Toxicology, Faculty of Veterinary and Animal Sciences, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan; 6Department of Applied Psychology, Faculty of Social Sciences, The Islamia University of Bahawalpur, Bahawalpur, 63100, PakistanCorrespondence: Shazia Rehman, Department of Psychiatry, National Clinical Research Center for Mental Disorders, and National Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, People’s Republic of China, Tel +86-13308429613, Email rehmanshazia.malik@gmail.comBackground: While bedtime procrastination is commonly associated with adverse outcomes such as poor sleep quality, the mechanisms mediating these effects remain underexplored. …”
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Pneumocystis Jirovecii Pneumonia in Two Immunosuppressed Non-HIV Infected Patients: A Clinical and Therapeutic Analysis
Published 2025-01-01“…Weiran Li, Mao Hua, Jin Guo, Wenbo Jia Department of Clinical Medicine, School of Medicine, Qinghai University, Xining, People’s Republic of ChinaCorrespondence: Mao Hua, Qinghai University Affiliated Hospital, No. 29 Tongren Road, Chengxi District, Xining, Qinghai Province, 810006, People’s Republic of China, Tel +86 0971-6162000, Email qhdxxxgk@126.comAbstract: Pneumocystis jirovecii pneumonia (PJP) is an opportunistic fungal infection that often occurs secondary to human immunodeficiency virus (HIV) infection. …”
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1155
Mitochondria-Targeted Biomaterials-Regulating Macrophage Polarization Opens New Perspectives for Disease Treatment
Published 2025-02-01“…Zui Tian,* Xudong Wang,* Shuai Chen,* Zijian Guo, Jingkai Di, Chuan Xiang Department of Orthopedics, Second Hospital of Shanxi Medical University, Taiyuan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chuan Xiang, Department of Orthopedics, Second Hospital of Shanxi Medical University, Taiyuan, People’s Republic of China, Email chuanxiang@sxmu.edu.cnAbstract: Macrophage immunotherapy is an emerging therapeutic approach designed for modulating the immune response to alleviate disease symptoms. …”
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1156
Multiwavelength Emission of Gamma-Ray Burst Prompt Phase. II. Spectral Polarimetry
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1157
Uncovering the Heterogeneity of Signaling Pathways in Skin Cutaneous Melanoma: Insights into Prognostic Values and Immune Interactions
Published 2025-01-01“…Yufang Liu,1,* Chunyan Li,2,* Weiwei Deng2 1Department of Dermatology and Venereology, Fuyang People’s Hospital, Fuyang, Anhui, 236000, People’s Republic of China; 2Department of Dermatology and Venereology, Dermatology Hospital of Southern Medical University, Department of Dermatology, Guangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Weiwei Deng, Email dengww@smu.edu.cnBackground: Signaling pathways play crucial roles in tumor cells. …”
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Drug Delivery System Targeting Cancer-Associated Fibroblast for Improving Immunotherapy
Published 2025-01-01“…Zhongsong Zhang,1 Rong Wang,1 Long Chen2 1School of Clinical Medicine, Chengdu Medical College, Chengdu, 610550, People’s Republic of China; 2School of Basic Medical Sciences, Chengdu Medical College, Chengdu, 610550, People’s Republic of ChinaCorrespondence: Long Chen, Email chenlong@cmc.edu.cnAbstract: Cancer-associated fibroblasts (CAFs) are a heterogeneous population of non-malignant cells that play a crucial role in the tumor microenvironment, increasingly recognized as key contributors to cancer progression, metastasis, and treatment resistance. …”
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Antimicrobial Activity and Metabolomic Analysis of Linalool Against Pathogenic Bacteria Methicillin-Resistant Staphylococcus aureus
Published 2025-02-01“…Nana Long,1,2 Min Qiu,2 Youwei Zuo,1 Hongping Deng1 1Center for Biodiversity Conservation and Utilization, School of Life Sciences, Southwest University, Beibei, Chongqing, People’s Republic of China; 2School of Laboratory Medicine, Chengdu Medical College, Chengdu, Sichuan, People’s Republic of ChinaCorrespondence: Hongping Deng, Email denghp@swu.edu.cnPurpose: The purpose of this study was to evaluate the antibacterial activity and mechanism of linalool against Methicillin-resistant Staphylococcus aureus (MRSA).Methods: The determination of the antibacterial activity of linalool against clinically isolated MRSA strains was based on the minimum inhibitory concentration (MIC) and growth curve analysis. …”
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Research Progress on Biomaterials for Spinal Cord Repair
Published 2025-02-01“…Zhenglie Liao,1,* Qianyi Bao,1,* Saijilahu,2 Chimedragchaa Chimedtseren,3 Khaliunaa Tumurbaatar,3 Saijilafu1 1Key Laboratory of Novel Targets and Drug Study for Neural Repair of Zhejiang Province, School of Medicine, Hangzhou City University, Hangzhou, People’s Republic of China; 2Tongliao Centers for Disease Control and Prevention, Tongliao, Inner Mongolia, People’s Republic of China; 3Institute of Traditional Medicine and Technology of Mongolia, Ulaanbaatar city, Mongolia*These authors contributed equally to this workCorrespondence: Saijilafu, Email saijlf@hzcu.edu.cnAbstract: Spinal cord injury (SCI) is a very destructive disease of the central nervous system that often causes irreversible nerve damage. …”
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