Investigation of the Influence of Deletional and Non-Deletional Hemoglobin H Disease on Pregnancy Outcomes by Zhao KS, Pan QA, Yang HY, Su JY, Deng L

“…Kai Sun Zhao,1,* Qiao Ai Pan,2,* Hong Yan Yang,2 Jun You Su,2 Li Deng2 1Department of Obstetrics, The Second Nanning People’s Hospital (The Third Affiliated Hospital of Guangxi Medical University), Nanning, Guangxi, 530031, People’s Republic of China; 2Department of Obstetrics, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530007, People’s Republic of China*These authors contributed equally to this workCorrespondence: Li Deng; Junyou Su, Department of Obstetrics, The Second Affiliated Hospital of Guangxi Medical University, No. 166, Daxuedong Road, Xixiangtang District, Nanning, Guangxi Zhuang Autonomous Region, People’s Republic of China, Tel +86 13877105871 ; +86 15277199813, Email dengli@gxmu.edu.cn; sujunyou@sr.gxmu.edu.cnObjective: The study aimed to provide clinical evidence regarding the perinatal management of HbH disease by comparing and analyzing blood routine, anemia characteristics, and their influence on pregnancy outcomes in patients with common deletional and non-deletional HbH disease at various pregnancy stages.Patients and Methods: From May 2017 to October 2023, a comparative analysis was conducted on pregnant women undergoing treatment at the Second Affiliated Hospital of Guangxi Medical University and the Second Nanning People’s Hospital. …”
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Gonadotropin Releasing Hormone Agonists Combined with Hormone Replacement Therapy Significantly Improves Reproductive Outcomes for Patients with Thin Endometrium and Intramural Fib... by Wei L, Tian B, Wang S, Xu S, Zhang C

“…Longlong Wei,1,2 Bing Tian,2 Shuna Wang,2 Siyue Xu,2 Cuilian Zhang1,2 1People’s Hospital of Zhengzhou University, Zhengzhou, Henan, 45003, People’s Republic of China; 2Department of Reproductive Medicine Center, Henan Provincial People’s Hospital, Zhengzhou, Henan, 45003, People’s Republic of ChinaCorrespondence: Cuilian Zhang, People’s Hospital of Zhengzhou University, No. 7, Wei Wu Road, Zhengzhou City, Henan Province, 450003, People’s Republic of China, Email luckyzcl@qq.comBackground: Both intramural myomas and thin endometrium exert a detrimental influence on the outcomes of assisted reproductive technology (ART). …”
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Distribution and Related Influencing Factors of AMH Level in Family-Planning Women of Childbearing Age: A Cross-Sectional Study from Beijing, China by Song J, Gao S, Zhao L, Tong X

“…Jinwei Song,1,* Songkun Gao,2,* Lixia Zhao,1 Xiaolong Tong1 1Women ‘s Health Department, Xicheng District Maternal and Child Health Care Hospital, Beijing, 100054, People’s Republic of China; 2Gynecologic Oncology Department,Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, Beijing, 100026, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jinwei Song; Xiaolong Tong, Women ‘s Health Department, Xicheng District Maternal and Child Health Care Hospital, Building 19, Pingyuanli Community, Baizhifang Street, Xicheng District, Beijing, 100054, People’s Republic of China, Email songjinwei2023@163.com; 18519309607@163.comPurpose: This study aimed to analyze the distribution and factors influencing anti-Müllerian hormone (AMH) levels among family-planning women of childbearing age in Beijing, China.Patients and Methods: We collected the data of 3,236 family-planning women of childbearing age who underwent pre-pregnancy examinations at Xicheng District Maternal and Child Health Hospital in Beijing between October 2021 and July 2024. …”
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Metformin Ameliorates Ulcerative Colitis Through Inhibiting NLRP3 Inflammasome Activation by Cao R, Jing J, Ma Y, Qi W, Huang X, Zhang C, Lu Z, He J, Wang G, Ma Y, Zhang H

“…Run Cao,1,* Jing Jing,1,* Yuting Ma,1,2,* Wenqing Qi,1 Xinyu Huang,1 Chaofang Zhang,1 Zhizhuo Lu,1 Jiayi He,1 Guiling Wang,1 Yuanfang Ma,1 Hailong Zhang1 1Joint National Laboratory for Antibody Drug Engineering, the First Affiliated Hospital, Henan University, Kaifeng, Henan, People’s Republic of China; 2Xuzhou Central Hospital, Xuzhou, Jiangsu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hailong Zhang; Yuanfang Ma, Joint National Laboratory for Antibody Drug Engineering, the First Affiliated Hospital, Henan University, Kaifeng, Henan, People’s Republic of China, Email hailong6891@163.com; mayf@henu.edu.cnPurpose: Metformin (Met) is widely used to treat a variety of diseases, but its role in ulcerative colitis (UC) has not been fully elucidated. …”
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Effect of Dietary Magnesium on the Association Between Serum Uric Acid and Female Infertility by Xin X, Zhang Q, Xu J, Huang J

“…Xiaoqin Xin,1 Qi Zhang,2 Jing Xu,1 Jungao Huang3 1Department of Clinical Laboratory, Ganzhou People’s Hospital, Ganzhou, Jiangxi, People’s Republic of China; 2Department of Obstetrics and Gynecology, Ganzhou Maternal and Child Health Hospital, Ganzhou, Jiangxi, People’s Republic of China; 3Department of Medical Genetic, Ganzhou Maternal and Child Health Hospital, Ganzhou, Jiangxi, 341000, People’s Republic of ChinaCorrespondence: Jungao Huang, Email jungaohuang@sina.comBackground: Few studies have evaluated the correlation between serum uric acid (SUA) levels and the prevalence of female infertility in the general population, and the effect of magnesium intake on this correlation has not been investigated.Methods: All participants aged 18– 45 years at baseline were enrolled from the National Health and Nutritional Examination Surveys (NHANES) 2013– 2018. …”
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Tumor Microenvironment Responsive Key Nanomicelles for Effective Against Invasion and Metastasis in Ovarian Cancer Using Mice Model by Liu Y, Kong L, Yu Y, Zang J, Zhang L, Guo RB, Li ST, Cheng L, Li XT, Chen YQ

“…Yang Liu,1,2 Liang Kong,1,2 Yang Yu,1,2 Juan Zang,1,2 Lu Zhang,1,2 Rui-Bo Guo,1,2 Shu-Tong Li,1,2 Lan Cheng,1,2 Xue-Tao Li,1,2 You-Qiang Chen1,2 1School of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian, 116600, People’s Republic of China; 2Shenyang Key Laboratory of Chinese Medicine Targeted Delivery Key Laboratory, Shenyang, 110847, People’s Republic of ChinaCorrespondence: Xue-Tao Li; You-Qiang Chen, School of Pharmacy, Liaoning University of Traditional Chinese Medicine, Shengming 1 Road 77, Double D Port, Dalian, 116600, People’s Republic of China, Tel +86411 8589 0170, Fax +86411 8589 0128, Email lixuetao1979@163.com; 89427765@qq.comBackground: Ovarian cancer is difficult to detect in its early stages, and it has a high potential for invasion and metastasis, along with a high rate of recurrence. …”
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Integrative Bioinformatics Analysis of Pyroptosis-Related Genes and Analysis of Immune Cell Infiltration in Infantile Hemangioma Regression by Liu L, Lin S, Bai J, Zhang B

“…Lan Liu,1,2,* Sheng Lin,1,2,* Jianxi Bai,1,2 Bing Zhang1,2 1Pediatric Surgery Department, Fujian Children’s Hospital (Fujian Branch of Shanghai Children’s Medical Center), Fuzhou City, Fujian Province, People’s Republic of China; 2Pediatric Surgery Department, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou City, Fujian Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jianxi Bai, Pediatric Surgery Department, Fujian Children’s Hospital (Fujian Branch of Shanghai Children’s Medical Center), 966 hengyu Road, Jinan District, Fuzhou City, Fujian Province, People’s Republic of China, Tel +8615806032159, Email bjxqqq@126.comBackground: Infantile hemangiomas (IHs) are characterized by spontaneous regression, and their pathogenesis involves immune cell infiltration and programmed cell death. …”
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Elucidating the Role of HIF-1α/YAP Signaling Pathway in Regulating Inflammation in Human Periodontal Stem Cells: An in vitro Study by Zhao HW, Liu ST, Wang XJ, Zhang XM, Ma X

“…Hui-Wei Zhao,1 Shu-Tai Liu,2 Xiang-Jin Wang,1 Xue-Mei Zhang,1 Xiang Ma1 1Department of Periodontology, The Affiliated Yantai Stomatological Hospital, Binzhou Medical University, Yantai, 264000, People’s Republic of China; 2Department of Periodontology, Shenzhen Stomatology Hospital, Shenzhen, 518000, People’s Republic of ChinaCorrespondence: Xiang Ma, Department of Periodontology, The Affiliated Yantai Stomatological Hospital, Binzhou Medical University, 148 North Road, YanTai, People’s Republic of China, Email MaXiang900218@163.comBackground and Objective: Periodontitis is a chronic inflammatory disease caused by dental plaque accumulation, leading to damage of periodontal tissues and potential tooth loss. …”
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The Efficacy and Brain Network Mechanism of Acupuncture for Knee Osteoarthritis: A Study Protocol for Randomized Controlled Neuroimaging Trial by Sun YY, Wang ML, Zhao RH, Hao MY, Song S, Zhou Y, Zhang N

“…Yi-Yang Sun,1 Ming-Lin Wang,2 Ruo-Han Zhao,1 Ming-Yao Hao,3 Shuai Song,3 Yue Zhou,3 Na Zhang1 1Department of Acupuncture-Moxibustion and Tuina, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, People’s Republic of China; 2Traditional Chinese Medicine Comprehensive Treatment Center, Shengli Oilfield Central Hospital, Jinan, Shandong, People’s Republic of China; 3External Treatment Center of Traditional Chinese Medicine, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, People’s Republic of ChinaCorrespondence: Na Zhang, Email zhangna2008zhentui@163.comPurpose: Knee osteoarthritis (KOA) is a prevalent degenerative bone and joint disease observed in clinical practice. …”
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Role of Aging in Ulcerative Colitis Pathogenesis: A Focus on ETS1 as a Promising Biomarker by Ni M, Peng W, Wang X, Li J

“…Man Ni,1,2 Weilong Peng,1,2 Xiaoguang Wang,1,2 Jingui Li1,2 1School of Veterinary Medicine, Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, 225009, People’s Republic of China; 2Joint International Research Laboratory of Agriculture and Agri-Product Safety, the Ministry of Education of China, Yangzhou University, Yangzhou, Jiangsu, 225009, People’s Republic of ChinaCorrespondence: Jingui Li, School of Veterinary Medicine, Yangzhou University, No. 48, Daxue North Road, Hanjiang District, Yangzhou City, Jiangsu, 225009, People’s Republic of China, Email jgli@yzu.edu.cnPurpose: An increasing proportion of the aging population has led to a rapid increase in the number of elderly patients with ulcerative colitis (UC). …”
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CECT-Based Radiomic Nomogram of Different Machine Learning Models for Differentiating Malignant and Benign Solid-Containing Renal Masses by Qian L, Fu B, He H, Liu S, Lu R

“…Lu Qian,1,* BinHai Fu,2,* Hong He,2 Shan Liu,1 RenCai Lu2 1Department of Pathology, the First People’s Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, 650032, People’s Republic of China; 2Department of Nuclear Medicine, The First People’s Hospital of Yunnan Province, the Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, 650032, People’s Republic of China*These authors contributed equally to this workCorrespondence: RenCai Lu, Department of Nuclear Medicine, The First People’s Hospital of Yunnan Province, the Affiliated Hospital of Kunming University of Science and Technology, No. 157 Jinbi Road, Kunming, Yunnan, 650032, People’s Republic of China, Tel +86 087163614503, Email lrc_09@126.comObjective: This study aimed to explore the value of a radiomic nomogram based on contrast-enhanced computed tomography (CECT) for differentiating benign and malignant solid-containing renal masses.Materials and Methods: A total of 122 patients with pathologically confirmed benign (n=47) or malignant (n=75) solid-containing renal masses were enrolled in this study. …”
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Association Between Allometric Body Shape Indices and Osteoporosis in Postmenopausal Women: A Cross-Sectional Study from NHANES by Zhao S, Pan X

“…Songfeng Zhao,1,2 Xin Pan1,2 1Department of Endocrinology, The First People’s Hospital of Xiaoshan District, Hangzhou, Zhejiang, People’s Republic of China; 2Department of Endocrinology, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, People’s Republic of ChinaCorrespondence: Xin Pan, Department of Endocrinology, The First People’s Hospital of Xiaoshan District, No. 199 South Shixin Road, Xiaoshan District, Hangzhou, Zhejiang, People’s Republic of China, Tel +86-0571-83807971, Email 344132702@qq.comBackground: Osteoporosis is a common health concern in postmenopausal women. …”
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Analysis and Validation of Autophagy-Related Gene Biomarkers and Immune Cell Infiltration Characteristic in Bronchopulmonary Dysplasia by Integrating Bioinformatics and Machine Lea... by Xiao S, Ding Y, Du C, Lv Y, Yang S, Zheng Q, Wang Z, Zheng Q, Huang M, Xiao Q, Ren Z, Bi G, Yang J

“…Shuzhe Xiao,1,* Yue Ding,1,* Chen Du,1,* Yiting Lv,1 Shumei Yang,1,2 Qi Zheng,3 Zhiqiu Wang,3 Qiaoli Zheng,3 Meifang Huang,1 Qingyan Xiao,1 Zhuxiao Ren,2 Guangliang Bi,1 Jie Yang1,2 1Department of Neonatology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, People’s Republic of China; 2Department of Neonatology, Guangdong Women and Children Hospital, Guangzhou, 511442, People’s Republic of China; 3The First Clinical Medical College of Southern Medical University, Guangzhou, 510515, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jie Yang; Guangliang Bi, Email Jieyang0830@126.com; bader515@163.comBackground: Autophagy and immunity play important regulatory roles in lung developmental disorders. …”
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Omentin-1, a Protective Adipokine for Irritable Bowel Syndrome by Gao Y, Chen C, Huang X, Liu Y, Zhou Z, Pan Y

“…Yanping Gao,1,2,* Chen Chen,1,2,* Xijing Huang,2 Ya Liu,1 Zhou Zhou,1 Yan Pan1 1Department of Gastroenterology, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, People’s Republic of China; 2Clinical Immunology Translational Medicine Key Laboratory of Sichuan Province, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yan Pan; Zhou Zhou, Sichuan Provincial People’s Hospital, 32 The First Ring Road West 2, Chengdu, Sichuan, 610072, People’s Republic of China, Email panyan2211@163.com; doublezhou2006@126.comIntroduction: Irritable bowel syndrome (IBS) is characterized by patients’ high level of suffering. …”
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Diversity in Adaptive Evolution of Methicillin-Resistant Staphylococcus aureus Clinical Isolates Under Exposure to Continuous Linezolid Stress in vitro by Han T, Jia T, Wang J

“…Tala Han,1 Ting Jia,1 Junrui Wang1,2 1Department of Laboratory Medicine, Affiliated Hospital of Inner Mongolian Medical University, Hohhot, 010050, People’s Republic of China; 2Inner Mongolia Key Laboratory of Clinical Pathogenic Microorganism, The Affiliated Hospital of Inner Mongolian Medical University, Hohhot, 010050, People’s Republic of ChinaCorrespondence: Junrui Wang, Clinical Laboratory, Affiliated hospital of Inner Mongolian Medical University, Hohhot, 010050, People’s Republic of China, Tel +86 04713451315, Email wangjunrui123@yeah.netBackground: Linezolid resistance in methicillin-resistant Staphylococcus aureus (MRSA) was reported frequently in recent years, but the mechanism underlying this process was less reported, especially for clinical isolates with different genetic background. …”
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Multicenter Surveillance of Pseudomonas aeruginosa Isolates From Blood: Clinical Distribution Characteristics and Antibiotic Resistance Trends in Hebei Province, China (2016–... by Qiang C, Liu X, Qin P, Wen H, Li Z, Yang J, Niu Y, Wang W, Ouyang Z, Zhao M, Li J, Zhang Y, Zhao J

“…Cuixin Qiang,1,* Xiaoxuan Liu,1,* Pu Qin,1 Hainan Wen,2 Zhirong Li,1 Jing Yang,1 Yanan Niu,1 Weigang Wang,1 Zirou Ouyang,1 Min Zhao,1 Jiayiren Li,1 Yulian Zhang,1 Jianhong Zhao1 1The Second Hospital of Hebei Medical University, Hebei Provincial Center for Clinical Laboratories, Shijiazhuang, Hebei, People’s Republic of China; 2Department of Laboratory Medicine, Affiliated Hospital of Chengde Medical University, Chengde, Hebei, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jianhong Zhao, The Second Hospital of Hebei Medical University, Hebei Provincial Center for Clinical Laboratories, Shijiazhuang, Hebei, People’s Republic of China, Tel +86 0311 66002711, Email zhaojh_2002@hebmu.edu.cnPurpose: To analyze the clinical distribution and antimicrobial resistance of Pseudomonas aeruginosa (P. aeruginosa) isolated from blood specimens in 75 hospitals in Hebei Province from 2016 to 2021 to aid in the rational selection of antimicrobial drugs.Patients and Methods: WHONET 5.6 and SPSS 24.0 were used to retrospectively analyze clinical distribution characteristics and variations in drug-resistance.Results: Between 2016 and 2021, 2208 P. aeruginosa strains were detected in blood specimens from Hebei Province. …”
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Environmental PM2.5 Exposure: An Ignored Factor Associated with Blood Cadmium Level in Hemodialysis Patients by Hsu CW, Chan MJ, Weng CH, Tsai TY, Yen TH, Huang WH

“…Ching-Wei Hsu,1,2 Ming-Jen Chan,1,2 Cheng-Hao Weng,1,2 Tsung-Yu Tsai,1,2 Tzung-Hai Yen,1,2 Wen-Hung Huang1,2 1Department of Nephrology and Clinical Poison Center, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan, Republic of China; 2Chang Gung University, College of Medicine, Taoyuan, Taiwan, Republic of ChinaCorrespondence: Wen-Hung Huang, Department of Nephrology and Clinical Poison Center, Chang Gung Memorial Hospital, 199, Tung-Hwa North Road, Taipei, Taiwan, Republic of China, Tel +886-3-3281200-8181, Fax +886-3-3288662, Email williammedia@gmail.comBackground: The negative impacts of particulate matter with an aerodynamic diameter of 2.5 μm or less (PM2.5) are well known. …”
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Determination of the MEC90 of Oxycodone for Preventing Perioperative Shivering in Pregnant Patients Undergoing Caesarean Delivery with Neuraxial Anaesthesia: A Biased-Coin up-and-D... by Lu X, Chen K, Xuan Y, Shen M, Lei W, Huang Y, Sun J

“…Xinlei Lu,1,* Kaiyu Chen,1,2,* Ye Xuan,1,2 Mengting Shen,1,2 Weiping Lei,1 Yaqin Huang,1 Jianliang Sun1 1Department of Anaesthesiology, Affiliated Hangzhou First People’s Hospital, School of Medicine, Westlake University, Hangzhou, People’s Republic of China; 2The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jianliang Sun, Department of Anaesthesiology, Affiliated Hangzhou First People’s Hospital, School of Medicine, Westlake University, Hangzhou, People’s Republic of China, Email jxmzsjl@163.comBackground: Perioperative shivering is a common adverse reaction to neuraxial anaesthesia. …”
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Comparative Efficacy of Esketamine vs Sufentanil with Propofol for Sedation in EUS: A Randomized, Controlled Study by Liu C, Wang Y, Yin Y, Wang P, Ji X, Sun J, Zhao S, Jia Y, Liu S, Zhou Z

“…Cuicui Liu,1,* Yanting Wang,1,* Yanwei Yin,2 Pei Wang,1 Xiangyu Ji,1 Jian Sun,1 Shuo Zhao,1 Yanfang Jia,1 Shanling Liu,1 Zangong Zhou1 1Daytime Anesthesiology Department, the Affiliated Hospital of Qingdao University, Qingdao, Shandong Province, People’s Republic of China; 2Pain Department, the Affiliated Hospital of Qingdao University, Qingdao, Shandong Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zangong Zhou, Daytime Anesthesiology Department, the Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Shinan District, Qingdao, Shandong Province, 266000, People’s Republic of China, Tel +86 532-82912511, Email zhouzangong@qdu.edu.cnPurpose: This randomized, controlled trial aimed to assess the sedative effects of esketamine and sufentanil combined with propofol during EUS.Patients and Methods: Three hundred and forty patients undergone EUS were randomly divided into two groups to receive esketamine 0.25 mg/kg combined with propofol (esketamine group) or sufentanil 0.1 μg/kg combined with propofol (sufentanil group). …”
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Correlation Between Gastroesophageal Reflux Disease and Small Intestinal Bacterial Overgrowth: Analysis of Intestinal Microbiome and Metabolic Characteristics by Wang ZT, Tan WT, Huang JL, Zhang PF, Li Q, Wang MM, Meng MM, Su H, Guo CM, Liu H

“…Zi-Teng Wang,1,2,* Wen-Tao Tan,1,* Jia-Li Huang,1 Peng-Fei Zhang,3 Qian Li,1 Miao-Miao Wang,1 Ming-Ming Meng,1 Hui Su,1 Chun-Mei Guo,1 Hong Liu1 1Gastroenterology Department, Beijing Shijitan Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Gastroenterology Department, Beijing Ditan Hospital, Capital Medical University, Beijing, People’s Republic of China; 3Emergency Department, Beijing Tiantan Hospital, Capital Medical University, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hong Liu, Email liuhong_sjt@ccmu.edu.cnBackground: Our study examines the relationship between gastroesophageal reflux disease (GERD) and small intestinal bacterial overgrowth (SIBO), focusing on the potential impact of acid-suppressive drugs. …”
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