Role of Huangqin Qingre Chubi Capsule in the Reduction of the Risk of Re-Admission in Patients With Ankylosing Spondylitis: A Cohort Study by Qi Y, Liu J, Chen Y, Hu Y, Zhou Q, Huang D, Cong C, Li Y

“…Yajun Qi,1– 3 Jian Liu,1,3 Yiming Chen,1,3 Yuedi Hu,1,3 Qiao Zhou,1,3 Dan Huang,1,3 Chengzhi Cong,1,3 Yang Li1,3 1The First College of Clinical Medicine, Anhui University of Chinese Medicine, Hefei, Anhui Province, 230031, People’s Republic of China; 2College of Acupuncture and Massage, Anhui University of Chinese Medicine, Hefei, Anhui Province, 230012, People’s Republic of China; 3Department of Rheumatology and Immunology, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui Province, 230031, People’s Republic of ChinaCorrespondence: Jian Liu, Department of Rheumatology and Immunology, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui Province, 230031, People’s Republic of China, Email liujianahzy@126.comObjective: This study evaluates whether Huangqin Qingre Chubi Capsule (HQC), a traditional Chinese medicine (TCM) compound, is associated with the risk of re-admission in patients with ankylosing spondylitis (AS).Methods: In this study, we retrospectively collected the clinical data of 1,296 AS patients. …”
Get full text

Clinical Characteristics of Inpatients with Diabetic Foot Ulcer Admitted with Non-Ulcer Complaints: A Retrospective Study by Li L, Li Y, Qin S, Zeng J, Ma W, Wei D

“…Lan Li,1,2 Yue Li,2,3 Shuang Qin,2 Jing Zeng,2 Wanxia Ma,2 Dong Wei2 1Medical Examination Center, Chengdu Second People’s Hospital, Chengdu, 610017, People’s Republic of China; 2Department of Endocrinology and Metabolism, Diabetic Foot Care Center, Chengdu Second People’s Hospital, Chengdu, 610017, People’s Republic of China; 3Department of Clinical Medicine, Chengdu Medical College, Chengdu, 610500, People’s Republic of ChinaCorrespondence: Dong Wei, Department of Endocrinology and Metabolism, Diabetic Foot Care Center, The Chengdu Second People’s Hospital, Chengdu, Sichuan, 610017, People’s Republic of China, Tel/Fax +86 02867830801, Email weidong314@126.comBackground: Diabetic foot ulcer (DFU) inpatients admitted with non-ulcer complaints constitute a neglected group that might suffer from more non-standard treatments. …”
Get full text

Predicting Outcomes in Esophageal Squamous Cell Carcinoma Using scRNA‐Seq and Bulk RNA‐Seq: A Model Development and Validation Study by Jiaqi Zhang, Shunzhe Song, Yuqing Li, Aixia Gong

Get full text

Deep Learning for Discrimination of Early Spinal Tuberculosis from Acute Osteoporotic Vertebral Fracture on CT by Liu W, Wang J, Lei Y, Liu P, Han Z, Wang S, Liu B

“…Wenjun Liu,1 Jin Wang,2 Yiting Lei,1 Peng Liu,3 Zhenghan Han,1 Shichu Wang,1 Bo Liu1 1Department of Orthopedics, First Affiliated Hospital, Chongqing Medical University, Chongqing, People’s Republic of China; 2College of Medical Informatics, Chongqing Medical University, Chongqing, People’s Republic of China; 3Department of Orthopedics, Daping Hospital, Army Medical University, Chongqing, People’s Republic of ChinaCorrespondence: Bo Liu, Department of Orthopedics, First Affiliated Hospital, Chongqing Medical University, Chongqing, People’s Republic of China, Tel +8613996065698, Email boliu@hospital.cqmu.edu.cnBackground: Early differentiation between spinal tuberculosis (STB) and acute osteoporotic vertebral compression fracture (OVCF) is crucial for determining the appropriate clinical management and treatment pathway, thereby significantly impacting patient outcomes.Objective: To evaluate the efficacy of deep learning (DL) models using reconstructed sagittal CT images in the differentiation of early STB from acute OVCF, with the aim of enhancing diagnostic precision, reducing reliance on MRI and biopsies, and minimizing the risks of misdiagnosis.Methods: Data were collected from 373 patients, with 302 patients recruited from a university-affiliated hospital serving as the training and internal validation sets, and an additional 71 patients from another university-affiliated hospital serving as the external validation set. …”
Get full text

A Nomogram Model for Predicting Recurrent Coronary Thrombosis in Kawasaki Disease Patients by Zhou X, Peng Y, Yi Q

“…Xue Zhou,1– 4 Yue Peng,1– 4,* Qijian Yi1– 4,* 1Department of Cardiovascular Medicine, Children’s Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 2National Clinical Research Center for Child Health and Disorders, Children’s Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 3Ministry of Education Key Laboratory of Child Development and Disorders, Children’s Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 4Chongqing Key Laboratory of Pediatrics, Children’s Hospital of Chongqing Medical University, Chongqing,People’s Republic of China*These authors contributed equally to this workCorrespondence: Qijian Yi, Email qjyi@hospital.cqmu.edu.cnBackground: Coronary thrombosis is a serious cardiovascular complication of Kawasaki disease (KD), and recurrence of coronary thrombosis increases the short-term risk of myocardial infarction and the long-term risk of coronary artery disease. …”
Get full text

Construction of an Interpretable Model of the Risk of Post-Traumatic Brain Infarction Based on Machine Learning Algorithms: A Retrospective Study by Li S, Li H, Wu B, Pan R, Liu Y, Wang J, Wei D, Gao H

“…Shaoji Li,1,* Hongjian Li,2,* Baofang Wu,1,* Rujun Pan,3 Yuqi Liu,4 Jiayin Wang,1 De Wei,3 Hongzhi Gao1 1Department of Neurosurgery, the Second Affiliated Hospital of Fujian Medical University, Quanzhou, 362000, People’s Republic of China; 2School of Medical Imaging, North Sichuan Medical College, Nanchong, 634700, People’s Republic of China; 3Department of Neurosurgery, Fuzhou University Affiliated Provincial Hospital, Fuzhou, 350001, People’s Republic of China; 4Department of Intensive Care Unit, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, 362000, People’s Republic of China*These authors contributed equally to this workCorrespondence: De Wei; Hongzhi Gao, Email weidele@fjmu.edu.cn; gaohongzhi@fjmu.edu.cnBackground: Post-traumatic cerebral infarction (PTCI) is a severe complication resulting from traumatic brain injury (TBI), which can lead to permanent neurological damage or death. …”
Get full text

B Cell Activation, Differentiation, and Their Potential Molecular Mechanisms in Osteoarthritic Synovial Tissue by Lu P, Li Y, Yang S, Yao H, Tu B, Ning R

“…Peizhi Lu,1,2,* Ya Li,1,2,* Shuo Yang,2 Haoyu Yao,2 Bizhi Tu,2 Rende Ning1,2 1Graduate School, Bengbu Medical University, Bengbu, Anhui, People’s Republic of China; 2Department of Orthopedics, the Third Affiliated Hospital of Anhui Medical University, the First People’s Hospital of Hefei, Hefei, Anhui, People’s Republic of China*These authors contributed equally to this workCorrespondence: Bizhi Tu, Department of Orthopedics, the Third Affiliated Hospital of Anhui Medical University, the First People’s Hospital of Hefei, Hefei, Anhui, People’s Republic of China, Tel +86 15357483840, Email 1301535636@qq.com Rende Ning, Graduate School, Bengbu Medical University, Bengbu, Anhui, People’s Republic of China, Tel +86 13956966305, Email nrd1972@outlook.comObjective: The objective of this study was to characterize the activation and differentiation of B cells in the synovium of osteoarthritis (OA) and to explore the underlying molecular mechanisms.Methods: Peripheral blood and synovial samples from OA patients at different stages were collected, and flow cytometry was employed to analyze the activation and differentiation of B cells. …”
Get full text

Wnt3a Enhances Mesenchymal Stem Cell Engraftment and Differentiation in a Chronic Obstructive Pulmonary Disease Rat Model by Wu H, Zhong Y, Li Y, Zhou X, Zhao T, Wan D, Zhu Y, Zhang Z, Li X, Gan X

“…Huala Wu,1,* Yulan Zhong,2,* Yangjingsi Li,3 Xiangxiang Zhou,2 Tiantian Zhao,1 Daomou Wan,1 Yuanzhe Zhu,1 Zhiyan Zhang,1 Xiaolei Li,1,4 Xin Gan1,4 1Department of Respiratory and Critical Care Medicine, Jiangxi Provincial Key Laboratory of Respiratory Diseases, Jiangxi Institute of Respiratory Diseases, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330006, People’s Republic of China; 2Department of Respiratory and Critical Care Medicine, Chest Hospital of Jiangxi Province, Nanchang, Jiangxi, 330006, People’s Republic of China; 3Department of Respiratory and Critical Care Medicine, Jiangxi Provincial People’s Hospital, Nanchang, Jiangxi, 330006, People’s Republic of China; 4China-Japan Friendship Jiangxi Hospital, National Regional Center for Respiratory Medicine, Nanchang, Jiangxi, 330200, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xin Gan; Xiaolei Li, Email ganxin1207@126.com; xiaoleili1225@163.comBackground: Bone marrow mesenchymal stem cell (BMSC) therapy is a novel approach for treating COPD. …”
Get full text

The Association of Occipital Spur with Craniocervical Posture and Craniofacial Morphology by Cheng Q, Xiao C, Lau Rui Han S, Hu S, Wu X, Dong Y, Xiong X, Fang S

“…Qiaoyu Cheng,1 Chuqiao Xiao,1 Sophie Lau Rui Han,1 Shoushan Hu,1 Xiayanran Wu,1 Yanhua Dong,1 Xin Xiong,1 Shanbao Fang2 1State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, 610041, People’s Republic of China; 2Department of Orthodontics, College & Hospital of Stomatology, Guangxi Medical University, Nanning, Guangxi, 530021, People’s Republic of ChinaCorrespondence: Xin Xiong, State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, 610041, People’s Republic of China, Email drxiongxin@scu.edu.cn Shanbao Fang, Department of Orthodontics, College & Hospital of Stomatology, Guangxi Medical University, Nanning, Guangxi, 530021, People’s Republic of China, Email fangshanbao@gxmu.edu.cnPurpose: This cross-sectional study aimed to evaluate the relationship between occipital spur (OS) with both craniocervical posture and craniofacial morphology.Methods: The study involved 240 lateral cephalograms from subjects with and without OS. …”
Get full text

Engineered Perfluorochemical Cancer-Derived Exosomes Loaded with Indocyanine Green and Camptothecin Provide Targeted Photochemotherapy for Effective Cancer Treatment by Lee YH, Huang CY

“…Yu-Hsiang Lee,1– 3 Cheng-You Huang1 1Department of Biomedical Sciences and Engineering, National Central University, Taoyuan City, Taiwan, Republic of China; 2Department of Chemical and Materials Engineering, National Central University, Taoyuan City, Taiwan, Republic of China; 3Department of Medical Research, Cathay General Hospital, Taipei City, Taiwan, Republic of ChinaCorrespondence: Yu-Hsiang Lee, Department of Biomedical Sciences and Engineering, National Central University, No. 300, Jhongda Road, Taoyuan City, 320317, Taiwan, Republic of China, Tel +886-3-422-7151 Ext# 27755, Fax +886-3-280-4627, Email yuhsianl@ncu.edu.twBackground: Cancer treatments are still limited by various challenges, such as off-target drug delivery, posttreatment inflammation, and the hypoxic conditions in the tumor microenvironment; thus, the development of effective therapeutics remains highly desirable. …”
Get full text

Nuclear and Star Formation Activities in Nearby Galaxies: Roles of Gas Supply and Active Galactic Nucleus Feedback by Huynh Anh N. Le, Yongquan Xue

Get full text

The Detection Rate of Associated Mg ii Absorption Lines in Quasars Depends on Their Radio Emission by Zhi-Fu Chen, Luis C. Ho

Get full text

Exploring the impact of adenoid obstruction on the human nasal airflow through parallel computational fluid dynamics by Zhengzheng Yan, Xinhong Wang, Rongliang Chen

Get full text

Potential Functions and Causal Associations of GNLY in Primary Open-Angle Glaucoma: Integration of Blood-Derived Proteome, Transcriptome, and Experimental Verification by Wang D, Pu Y, Gao X, Zeng L, Li H

“…Dangdang Wang,1,2,* Yanyu Pu,1,2,* Xi Gao,1,2 Lihong Zeng,1,2 Hong Li1,2 1Department of Ophthalmology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 2Chongqing Key Laboratory for the Prevention and Treatment of Major Blinding Eye Diseases, Chongqing Eye Institute, Chongqing Branch of National Clinical Research Center for Ocular Diseases, Chongqing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hong Li, Department of Ophthalmology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China, Email lihong@hospital.cqmu.edu.cnPurpose: Genome-wide association studies (GWAS) have identified multiple genetic loci associated with primary open-angle glaucoma (POAG). …”
Get full text

Bibliometric Analysis of Global Pediatric Research on Cow‘s Milk Protein Allergy by Lin X, Chen Y, Lin W

“…Xiaolan Lin,1,* Yifan Chen,2,3,* Weidong Lin1 1Department of Pediatric Gastroenterology, Fuzhou Children’s Hospital of Fujian Medical University, Fuzhou, Fujian, People’s Republic of China; 2Shengli Clinical Medical College, Fujian Medical University, Fuzhou, Fujian, People’s Republic of China; 3Department of Gastrointestinal Surgery, Fujian Provincial Hospital, Fuzhou, Fujian, People’s Republic of China*These authors contributed equally to this workCorrespondence: Weidong Lin; Yifan Chen, Email lwd@fjmu.edu.cn; 597039383@qq.comBackground: Cow’s milk protein allergy (CMPA) is a prevalent food allergy in early childhood, significantly impacting the quality of life for affected children. …”
Get full text

Arctic sea ice melting has produced distinct sea ice-atmosphere coupled patterns by Bingyi Wu

Get full text

Deep Learning the Forecast of Galactic Cosmic-Ray Spectra by Yi-Lun Du, Xiaojian Song, Xi Luo

Get full text

Three-dimensional disordered alloy metamaterials: a new platform of structure-function integration by Xinxin Li, Liqiang Wang, Yang Lu

Get full text

The crystal structure of 2-(3,6-di-tert-butyl-1,8-diiodo-9H-carbazol-9-yl)acetonitrile, C22H24I2N2 by Tang Lin-Li, Zeng Fei

Get full text

Crystal structure of 2-(4-methoxyphenyl)-3-methyl-1,8-naphthyridine, C16H14N2O by Xiao Xin-Sheng, Jia Guo-Kai

Get full text