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781
Deciphering Immunometabolic Landscape in Rheumatoid Arthritis: Integrative Multiomics, Explainable Machine Learning and Experimental Validation
Published 2025-01-01“…Qiu Dong,1,* Jiayang Wu,2,3,* Huaguo Zhang,4,* Xinhui Chen,2,3 Xi Xu,2,3 Jifeng Chen,3 Changzheng Shi,2,3,5 Liangping Luo,3,5 Dong Zhang2,3 1Department of Bone and Joint Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, People’s Republic of China; 2Medical Imaging Centre, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, People’s Republic of China; 3The Guangzhou Key Laboratory of Molecular and Functional Imaging for Clinical Translation, the First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, People’s Republic of China; 4Department of Ultrasonography, the First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, People’s Republic of China; 5Medical Imaging Centre, the Fifth Affiliated Hospital of Jinan University, Heyuan, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Dong Zhang, Email lbzhangdong@126.comPurpose: Immunometabolism is pivotal in rheumatoid arthritis (RA) pathogenesis, yet the intricacies of its pathological regulatory mechanisms remain poorly understood. …”
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782
Osteoarthritis and Degree of Fatigue are Associated with Pain Levels in Patients with Fibromyalgia Syndrome: A Cross-Sectional Study of 394 Patients
Published 2025-01-01“…Zihan Wang,1,2,* Tianyi Lan,1,2,* Yuqiao Zhang,1,2 Zijia Guo,3 Hongwei Yu,4 Guiyao Sun,5 Zhitian Wang,6 Zeran Yan,1 Qingwen Tao,1 Yuan Xu1 1Traditional Chinese Medicine Department of Rheumatism, China-Japan Friendship Hospital, Beijing, People’s Republic of China; 2Graduate School, Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 3Graduate School, Inner Mongolia Medical University, Hohhot, People’s Republic of China; 4Department of Radiology, China-Japan Friendship Hospital, Beijing, People’s Republic of China; 5Department of Orthopedics, Shuangqiao Hospital, Beijing, People’s Republic of China; 6Science Faculty, University of Auckland, Auckland, New Zealand*These authors contributed equally to this workCorrespondence: Qingwen Tao; Yuan Xu, Email taoqg1@sina.com; xuyuan2004020@163.comObjective: To observe how osteoarthritis (OA) and degree of fatigue affect are associated with pain levels in patients with fibromyalgia syndrome (FMS).Methods: A cross-sectional study was conducted involving FMS patients. …”
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783
Research on smoke diffusion and evacuation routes of mine fires with complex roadway networks
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784
Investigating the Use of Generative Adversarial Networks-Based Deep Learning for Reducing Motion Artifacts in Cardiac Magnetic Resonance
Published 2025-02-01“…Ze-Peng Ma,1,2,* Yue-Ming Zhu,3,* Xiao-Dan Zhang,4 Yong-Xia Zhao,1 Wei Zheng,3 Shuang-Rui Yuan,1 Gao-Yang Li,1 Tian-Le Zhang1 1Department of Radiology, Affiliated Hospital of Hebei University/ Clinical Medical College, Hebei University, Baoding, 071000, People’s Republic of China; 2Hebei Key Laboratory of Precise Imaging of inflammation Tumors, Baoding, Hebei Province, 071000, People’s Republic of China; 3College of Electronic and Information Engineering, Hebei University, Baoding, Hebei Province, 071002, People’s Republic of China; 4Department of Ultrasound, Affiliated Hospital of Hebei University, Baoding, Hebei Province, 071000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiao-Dan Zhang, Department of Ultrasound, Affiliated Hospital of Hebei University, No. 212 of Yuhua East Road, Lianchi District, Baoding, 071000, People’s Republic of China, Tel +86 17325535302, Email xiaodanzhangzxd@126.comObjective: To evaluate the effectiveness of deep learning technology based on generative adversarial networks (GANs) in reducing motion artifacts in cardiac magnetic resonance (CMR) cine sequences.Methods: The training and testing datasets consisted of 2000 and 200 pairs of clear and blurry images, respectively, acquired through simulated motion artifacts in CMR cine sequences. …”
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785
Solar Modulation of AMS-02 Daily Proton and Helium Fluxes with Modified Force-field Approximation Models
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786
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787
Comment on “Parabolic Changes in Pain Scores Among Partial Herpes Zoster Patients: A Retrospective Study” [Letter]
Published 2025-01-01“…Yingjian Tan,1,* Yue Kang,2,* Rui Li1 1Department of Dermatology, Fuzhou First General Hospital, Fuzhou, People’s Republic of China; 2Department of Respiratory and Critical Care, Xinxiang Central Hospital, Xinxiang, Henan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yingjian Tan; Rui Li, Email dr.yingjian.tan@gmail.com; 292430384@qq.com…”
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788
Gelatin/Poly (Lactic-Co-Glycolic Acid)/Attapulgite Composite Scaffold Equipped with Teriparatide Microspheres for Osteogenesis in vitro and in vivo
Published 2025-01-01“…Zhenrui Zhao,1 Xiaofei Feng,1 Yuhao Zhao,1 Zhengdong Song,1 Ruihao Zhang,1 Kui Zhang,1 Yixiang He,1 Guoliang Chen,1 Jing Zhang,2 Wenji Wang3 1Department of Orthopedics, The First Clinical Medical College of Lanzhou University, Lanzhou, People’s Republic of China; 2Department of Orthopedics, Anlu People’s Hospital, Anlu, People’s Republic of China; 3Department of Orthopedics, the First Hospital of Lanzhou University, Lanzhou, People’s Republic of ChinaCorrespondence: Wenji Wang, The First Hospital of Lanzhou University, Lanzhou, 730000, People’s Republic of China, Tel +8613893221698, Email wwjldyy@163.comBackground: Given the risks associated with autologous bone transplantation and the limitations of allogeneic bone transplantation, scaffolds in bone tissue engineering that incorporate bioactive peptides are highly recommended. …”
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789
Clinical Outcome of Achilles Tendon Rupture Repaired by a Modified Minimally Invasive Percutaneous Suturing
Published 2025-01-01“…Xiaoyang Qi,1,* Danxia Zheng,2,* Zhijie Lei,3,* Jianglin Yu,3 Xusheng Qiu,1,3 Yixin Chen2 1Department of Orthopedics, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu Province, People’s Republic of China; 2Department of Orthopedics, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province, People’s Republic of China; 3Department of Orthopedics, Nanjing Drum Tower Hospital Clinical College of Jiangsu University, Nanjing, Jiangsu Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yixin Chen, Department of Orthopedics, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, No. 321, Zhongshan Road, Nanjing, Jiangsu Province, 210000, People’s Republic of China, Tel +86 15005149964, Email Chenyixin93@126.comPurpose: Minimally invasive percutaneous techniques offer a promising alternative to open surgical repair of the Achilles tendon. …”
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790
Effects of Baicalin on Gout Based on Network Pharmacology, Molecular Docking, and in vitro Experiments
Published 2025-02-01“…Chunliu Liu,1– 3,* Wei Liu,1,2,* Hang Lu,1,2 Yihua Fan,4 Aihua Wang1,2 1Department of Rheumatism and Immunity, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, People’s Republic of China; 2National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, People’s Republic of China; 3Department of Respiratory Medicine, Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital, Tianjin, People’s Republic of China; 4Department of Rheumatism and Immunity, Hospital of Chengdu University of Traditional Chinese Medicine, Sichuan Chengdu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wei Liu, Email fengshiliuwei@163.comPurpose: Baicalin is a flavonoid of Scutellaria baicalensis Georgi. …”
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791
Successful Mechanical Thrombectomy for Bilateral Anterior Cerebral Artery Occlusions in a Rare Anatomical Variant: A Case Report
Published 2025-01-01“…Beihai Ge,1 Jianjian Zhu,1 Fu Zhang,1 Xianyan Han,1 Yaqian Xia,1 Zeqiang Ji,1 Peili Sun,1 Yuqing Li,1 Huiying Zhang,1 Jianghong Guo2 1Department of Neurology, Rugao Affiliated Hospital of Nantong University, Rugao People’s Hospital, Nantong, Jiangsu, People’s Republic of China; 2Department of Cardiology, Rugao Affiliated Hospital of Nantong University, Rugao People’s Hospital, Nantong, Jiangsu, People’s Republic of ChinaCorrespondence: Jianghong Guo, Department of Cardiology, Rugao Affiliated Hospital of Nantong University, Rugao People’s Hospital, Nantong, Jiangsu, People’s Republic of China, Tel/Fax +86 51387312703, Email jianghongguo123@126.com Beihai Ge, Department of Neurology, Rugao Affiliated Hospital of Nantong University, Rugao People’s Hospital, Nantong, Jiangsu, People’s Republic of China, Tel/Fax +86 51387312703, Email beihaige@126.comBackground: Acute ischemic stroke (AIS) is usually caused by acute occlusion of the cerebral artery. …”
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792
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794
Reliability and Validity of a Chinese Version of Adaptive Cognitive Evaluation Tool in College Students
Published 2025-01-01“…Ze Yu,1,2,* Youyang Wang,1,2,* Yiyun Li,3 Wei Feng1,2 1Department of Psychological Medicine, Fudan University Shanghai Cancer Center, Shanghai, 200032, People’s Republic of China; 2Department of Oncology, Shanghai Medical College of Fudan University, Shanghai, 200032, People’s Republic of China; 3Stomatological Hospital and Dental School of Tongji University, Shanghai, 200072, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wei Feng, Department of Psychological Medicine, Fudan University Shanghai Cancer Center, Shanghai, 200032, People’s Republic of China, Email ffww06@163.comBackground: Cognition is central to acquiring knowledge and learning new experiences, critical for social behavior and quality of life. …”
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795
Transcript Changes of Placental Tissue in Gestational Diabetes Mellitus Based on Transcriptome Sequencing
Published 2025-01-01“…Yun Sun,1,* Yi Wang,1,* Chao Liu,2 Jie Yang,3 Qinwen Li,1 Fei Zhao1 1Department of Obstetrics, The Affiliated Taian City Central Hospital of Qingdao University, Taian, People’s Republic of China; 2Department of Obstetrics, Taian Maternal and Child Care Health Hospital, Taian, People’s Republic of China; 3Department of Gynaecology and Obstetrics, Liangshan County People’s Hospital, Jining, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qinwen Li; Fei Zhao, Department of Obstetrics, Taian Central Hospital (Taian Central Hospital affiliated to Qingdao University, Mount Taishan Medical Center), No. 29, Longtan Road, Mount Taishan District, Taian, Shandong, 271000, People’s Republic of China, Tel +86-13505482692, Email lqw81@126.com; 13505482692@163.comPurpose: This study aims to identify key genes that may be involved in the pathogenesis of gestational diabetes mellitus and to preliminarily elucidate the underlying mechanisms.Methods: High-throughput transcriptome sequencing was employed to identify Differentially expressed genes (DEGs) in placental tissue samples of GDM and normal pregnant women. …”
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796
Classification and Physical Characteristic Analysis of Fermi-GBM Gamma-Ray Bursts Based on Deep Learning
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797
Etiology, Risk Factors, and Antimicrobial Resistance in Recurrent Pyogenic Liver Abscesses: A Six-Year Analysis
Published 2025-01-01“…JinHua Cui,1 YaMan Liu,2 Hua Fu,1 MiaoHang Cui,1 JiZhong Li,3 ZiYu Bai,1 Jian Li1 1Department of Hepatobiliary Surgery, Affiliated Hospital of Chengde Medical College, Chengde City, Hebei Province, People’s Republic of China; 2Department of Gynaecology, Affiliated Hospital of Chengde Medical College, Chengde City, Hebei Province, People’s Republic of China; 3Department of Operating Room, Affiliated Hospital of Chengde Medical College, Chengde City, Hebei Province, People’s Republic of ChinaCorrespondence: Jian Li, Department of Hepatobiliary Surgery, Affiliated Hospital of Chengde Medical College, Chengde City, Hebei Province, People’s Republic of China, Email lijian111008@126.comAim: To perform a comparative analysis of the clinical data of patients with and without recurrent pyogenic liver abscess and explore the influencing factors, clinical characteristics, and pathogenic bacteria associated with the recurrence of liver abscesses.Patients and Methods: A retrospective analysis was conducted on 436 recently diagnosed patients with pyogenic liver abscess admitted to the Affiliated Hospital of Chengde Medical College between June 2017 and June 2023. …”
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798
Immune Dysregulation and Cellular Composition in Lichen Sclerosus Revealed by Integrative Epigenetic Analysis with Cell Type Deconvolution
Published 2025-01-01“…Jianwei Wang,1,* Hailang Fan,2,* Zhengqing Bao,1 Guizhong Li,1 Lingyan Wang,1 Dake Zhang2 1Urology Department, Beijing Jishuitan Hospital, Capital Medical University, Beijing, 102200, People’s Republic of China; 2Key Laboratory of Biomechanics and Mechanobiology, Ministry of Education; Key Laboratory of Innovation and Transformation of Advanced Medical Devices, Ministry of Industry and Information Technology; National Medical Innovation Platform for Industry-Education Integration in Advanced Medical Devices (Interdiscipline of Medicine and Engineering); School of Engineering Medicine, Beihang University, Beijing, 100191, People’s Republic of China*these authors contributed equally to the workCorrespondence: Lingyan Wang, Urology Department, Beijing Jishuitan Hospital, Capital Medical University, Beijing, People’s Republic of China, Email wang_lingyan@foxmail.com Dake Zhang, Key Laboratory of Biomechanics and Mechanobiology, Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Engineering Medicine, Beihang University, Beijing, People’s Republic of China, Email dakezhang@buaa.edu.cnBackground: Lichen sclerosus (LS) is a chronic inflammatory disease affecting skin and mucosal tissues, particularly external genitalia, with a risk of cancer. …”
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799
Unveiling the Prognostic Power of HRR in ICU-Admitted COPD Patients: A MIMIC-IV Database Study
Published 2025-01-01“…Yuan Wang,1 Dan Chen,2 Chunlu Zhang,3 Haiying Yang1 1Department of Respiratory and Critical Care Medicine, The Second People’s Hospital of Meishan City, Meishan, Sichuan, 620500, People’s Republic of China; 2Department of Respiratory Medicine, Yunchang Hospital, Meishan, Sichuan, 620500, People’s Republic of China; 3Department of Geriatrics, Chengdu Sixth People’s Hospital, Chengdu, Sichuan, 610051, People’s Republic of ChinaCorrespondence: Yuan Wang, Department of Respiratory and Critical Care Medicine, The Second People’s Hospital of Meishan City, Meishan, Sichuan, 620500, People’s Republic of China, Email 2693855887@qq.comObjective: This study sought to examine the potential relationship between Hemoglobin/Red Cell Distribution Width Ratio (HRR) and the all-cause mortality risk in critically ill patients with chronic obstructive pulmonary disease (COPD).Patients and Methods: In a retrospective analysis of the MIMIC-IV database, patients were divided into two groups based on a specific HRR threshold. …”
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800