Application of the 2021 AAPOS Guidelines in Clinics with Revision and Validation of SPOT Referral Criteria by Li R, Yan Q, Lin X, Wu Z, Zhu H, Guo W, Zhang P, Zuo F, Wu Z, Liu H, Huang D

“…Rui Li,1,* Qi Yan,2,* Xiao Lin,3,* Zhujian Wu,4 Hui Zhu,4 Wei Guo,4 Peibin Zhang,4 Feidi Zuo,5 Ziyan Wu,5 Hu Liu,4 Dan Huang4 1Department of Ophthalmology, Nanjing First Hospital, Nanjing Medical University, Nanjing, People’s Republic of China; 2Department of Ophthalmology, Children’s Hospital of Soochow University, Suzhou, People’s Republic of China; 3Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA; 4Department of Ophthalmology, the First Affiliated Hospital with Nanjing Medical University, Nanjing, People’s Republic of China; 5The Fourth School of Clinical Medicine of Nanjing Medical University, Nanjing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hu Liu; Dan Huang, Department of Ophthalmology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, 210029, People’s Republic of China, Tel +86 (25) 68136470, Fax +86 (25) 83275171, Email liuhu@njmu.edu.cn; huangdan@njmu.edu.cnPurpose: This study aims to validate and revise the Spot Vision Screener referral criteria for detecting amblyopia risk factors (ARFs), visually significant refractive error (VSRE), and amblyopia.Methods: In clinics, we gathered data from children aged 12 months to 7 years. …”
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Eculizumab treatment for Chinese patients with hemolytic paroxysmal nocturnal hemoglobinuria (PNH): efficacy and safety – a single-center study by Leyu Wang, Ziwei Liu, Chen Yang, Miao Chen, Bing Han

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Pyrvinium Pamoate Synergizes with Azoles in vitro and in vivo to Exert Antifungal Efficacy Against Candida auris and Other Candida Species by Zhang J, Li G, Hu J, Tan J, Zhang H, Zhou Y

“…Jinqing Zhang,1,* Gaolian Li,2,* Jing Hu,3,* Jingwen Tan,4 Heng Zhang,5 Yizheng Zhou5 1Department of Dermatology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Gynaecology, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, Hubei Province, People’s Republic of China; 3Department of Clinical Medicine, Xiangyang Polytechnic, Xiangyang, Hubei Province, People’s Republic of China; 4Department of Medical Mycology, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China; 5Department of Clinical Laboratory, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, Hubei Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yizheng Zhou, Email zhou_yizheng@163.comIntroduction: Treating infections caused by azole-resistant Candida spp. poses a significant challenge. …”
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Osteoporosis Awareness, Self-Efficacy and Health Beliefs Among Staff in an Obstetrics and Gynecology Hospital: A Cross-Sectional Study by Zhou Y, Xu Z, Zhang Z, Su J

“…Yun Zhou,1,* Zheyun Xu,2,* Zhifen Zhang,3 Jun Su4,5 1Outpatient Department, Hangzhou Women’s Hospital (Hangzhou Maternity and Child Health Care Hospital), Hangzhou, Zhejiang, 310008, People’s Republic of China; 2The Fourth Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, People’s Republic of China; 3Department of Obstetrics and Gynecology, Hangzhou Women’s Hospital (Hangzhou Maternity and Child Health Care Hospital), Hangzhou, Zhejiang, 310008, People’s Republic of China; 4School of Public Health, Hangzhou Normal University, Hangzhou, 311121, People’s Republic of China; 5Intensive Care Medicine Department, Hangzhou Women`s Hospital (Hangzhou Maternity and Child Health Care Hospital), Hangzhou, 310008, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jun Su, Email junjunsu@163.comBackground: We investigated the key factors that influence the awareness, health beliefs, and self-efficacy of osteoporosis among the staff of an obstetrics and gynecology hospital to identify the key target population for carrying out education and promotion in medical institutions, hoping to improve women’s awareness and prevention and treatment consciousness of osteoporosis from the source.Methods: A cross-sectional study was conducted from October 15 to October 24 in 2023, and 200 staff members were randomly sampled from an obstetrics and gynecology hospital in Hangzhou city for a questionnaire survey. …”
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Investigating Brain Structure and Functional Alterations in the Transition from Acute to Chronic Neck Pain: A Resting-State fMRI Study by Gao Z, Cui MJ, Wang HJ, Zhang J, Xu C, Ji LX

“…Zhen Gao,1,* Meng-Jie Cui,2,* Hai-Jun Wang,2 Jing Zhang,3 Cheng Xu,4 Lai-Xi Ji2 1Experimental Management Center, Shanxi University of Traditional Chinese Medicine, Taiyuan, Shanxi, 030024, People’s Republic of China; 2Second Clinical Medical College, Shanxi University of Traditional Chinese Medicine, Taiyuan, Shanxi, 030024, People’s Republic of China; 3Acupuncture and Moxibustion Department II, Affiliated Hospital of Shanxi University of Traditional Chinese Medicine, Taiyuan, Shanxi, 030024, People’s Republic of China; 4Radiology Department, Shanxi Provincial People’s Hospital, Taiyuan, Shanxi, 030012, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lai-Xi Ji, Second Clinical Medical College, Shanxi University of Traditional Chinese Medicine, Jinci Road Section 1, No. 89, Taiyuan, Shanxi, 030024, People’s Republic of China, Email jlx@sxtcm.edu.cnPurpose: The objective of this research is to delve into the central pathological mechanisms involved in the transformation from acute to chronic pain.Patients and Methods: This study enrolled 86 individuals with acute neck pain and 89 with chronic neck pain. …”
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Characteristics, Incidence, and Management of Immune Checkpoint Inhibitors Related Cardiovascular Adverse Events in Real-World Practice-A Retrospective Study in Chinese Han Populat... by Wang RH, Chen Y, Lou YL, Lu YL, Xu HM

“…Rong-Hua Wang,1 Yin Chen,1 Ya-Ling Lou,1 Yu-Liang Lu,2 Hui-Min Xu3 1Department of Pharmacy, HuZhou Central Hospital (The Fifth School of Clinical Medicine of Zhejiang Chinese Medical University), Huzhou, People’s Republic of China; 2Department of Cardiology, HuZhou Central Hospital (The Fifth School of Clinical Medicine of Zhejiang Chinese Medical University), Huzhou, People’s Republic of China; 3Department of Pharmacy, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of ChinaCorrespondence: Rong-Hua Wang, Department of Pharmacy HuZhou Central Hospital (The Fifth School of Clinical Medicine of Zhejiang Chinese Medical University), No. 1558 Sanhuan North Road, Wuxing District, Huzhou, Zhejiang, 313000, People’s Republic of China, Email legend.blue@163.com Hui-Min Xu, Department of Pharmacy Second Affiliated Hospital, Zhejiang University School of Medicine, No. 88 Jiefang Road, Shangcheng District, Hangzhou, Zhejiang, 310009, People’s Republic of China, Email xuhuimin78@zju.edu.cnPurpose: This study aimed to elaborate on the incidence, clinical features, and management of immune checkpoint inhibitors (ICIs) related cardiovascular adverse events (CVAEs) in real-world practice.Patients and Methods: We performed a retrospective chart review study on patients receiving at least one dose of ICI therapy at a Chinese tertiary hospital from March 2020 to March 2021. …”
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Implementing Cancer Pain Management Training for Pharmacists Using the Kirkpatrick Evaluation Model by Liu Y, Peng Y, Zhu B, Xia Z, Yuan Y, Zhang F

“…Yu Liu,1 Yang Peng,2 Bimin Zhu,2 Zhihua Xia,1 Yonghua Yuan,3 Fujun Zhang4 1Department of Pharmacy, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People’s Republic of China; 2Department of Pharmacy, Dianjiang County People’s Hospital, Chongqing, 408300, People’s Republic of China; 3College of Pharmacy, Chongqing Medical University, Chongqing, 400016, People’s Republic of China; 4Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People’s Republic of ChinaCorrespondence: Fujun Zhang, Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, Chongqing, 400016, People’s Republic of China, Email cnzfj@cqmu.edu.cnPurpose: To develop a training program on cancer pain management for pharmacists and to evaluate the effectiveness of the training.Methods: The program developed a well-structured curriculum and subsequent evaluation of training effectiveness, guided by the Kirkpatrick four-tier evaluation model, including reaction, learning, behavior, and results. …”
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The Loge GDR Was Strongly Associated with NAFLD as a Predictor in Normoalbuminuric Patients with Type 2 Diabetes by Ji B, Gao G, Zhao H, Sheng J, Ma X, Shi S, Ban B

“…Baolan Ji,1 Guanqi Gao,2 Hongyan Zhao,2,3 Jie Sheng,2,3 Xuan Ma,2,3 Shuwei Shi,1– 3 Bo Ban1,2 1Department of Endocrinology, Affiliated Hospital of Jining Medical University, Jining, Shandong, 272029, People’s Republic of China; 2Department of Endocrinology, Linyi People’s Hospital Affiliated to Shandong Second Medical University, Linyi, Shandong, 276034, People’s Republic of China; 3School of Clinical Medicine, Shandong Second Medical University, Weifang, Shandong, 261000, People’s Republic of ChinaCorrespondence: Bo Ban, Department of Endocrinology, Affiliated Hospital of Jining Medical University, 89 Guhuai Road, Jining, Shandong, 272029, People’s Republic of China, Email banbo2011@163.com Shuwei Shi, School of Clinical Medicine, Shandong Second Medical University, Weifang, Shandong, 261000, People’s Republic of China, Email ssw15689286547@163.comAim: Attenuated insulin-sensitivity (IS) is a characteristic of type 2 diabetes (T2D) and is closely linked to non-alcoholic fatty liver disease (NAFLD). …”
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A Multiple-detection-heads Machine Learning Algorithm for Detecting White Dwarfs by Jiangchuan Zhang, Yude Bu, Mengmeng Zhang, Duo Xie, Zhenping Yi

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Research Progress on Neural Processing of Hand and Forearm Tactile Sensation: A Review Based on fMRI Research by Chen H, Fu S, Zhi X, Wang Y, Liu F, Li Y, Ren F, Zhang J, Ren L, Wang Y

“…Hao Chen,1,* Shifang Fu,2,* Xiaoyu Zhi,2 Yu Wang,2 Fanqi Liu,2 Yuetong Li,2 Fengjiao Ren,2 Junfeng Zhang,1,3,4 Longsheng Ren,1 Yanguo Wang2 1Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, People’s Republic of China; 2Rehabilitation Department, Tianjin University of Traditional Chinese Medicine Second Affiliated Hospital, Tianjin, 300250, People’s Republic of China; 3Rehabilitation Center, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, People’s Republic of China; 4National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, 300381, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yanguo Wang, Tianjin University of Traditional Chinese Medicine Second Affiliated Hospital, Tianjin, 300250, People’s Republic of China, Email tjwangyanguo@163.comAbstract: Tactile perception is one of the important ways through which humans interact with the external environment. …”
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In vitro Antibacterial Effect of Reduning Combined with Polymyxin on Carbapenem Resistant Klebsiella pneumoniae by Shangguan ZF, Chen HL, Li YF, Shi N, Mao QF

“…Zui-Fei Shangguan,1 Hong-Lei Chen,2 Yi-Fan Li,3 Na Shi,4 Qi-Fen Mao2 1Department of Clinical Laboratory, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, Zhejiang, 310006, People’s Republic of China; 2Department of Clinical Laboratory, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang, 310012, People’s Republic of China; 3College of Laboratory Medicine and College of Bioengineering, Hangzhou Medical University, Hangzhou, Zhejiang, 311399, People’s Republic of China; 4Medical Laboratory, Second Sanatorium of Air Force Healthcare Center for Special Services, Hangzhou, Zhejiang, 310007, People’s Republic of ChinaCorrespondence: Qi-Fen Mao, Department of Clinical Laboratory, Tongde Hospital of Zhejiang Province, 234#, Gucui Road, Hangzhou, Zhejiang, 310012, People’s Republic of China, Email maoqifen@alu.zcmu.edu.cnObjective: This study aimed to investigate the status of carbapenem-resistant strains of Klebsiella pneumoniae isolated from the Department of Microbiology, Zhejiang Tongde Hospital between September 2023 and February 2024, and to examine the in vitro antibacterial effect of Reduning combined with polymyxin on carbapenem-resistant Klebsiella pneumoniae (CRKP), which may provide evidence on the application of Reduning in the clinical anti-infective therapy.Methods: A total of 50 different isolates of CRKP were collected, and the minimum inhibitory concentrations (MIC) of polymyxin, Reduning and polymyxin plus Reduning were measured with microbroth dilution method. …”
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Progress in the Study of Intratumoral Microorganisms in Hepatocellular Carcinoma by Song Y, Tian S, Li Z, Miao J, Wu M, Xu T, Wu X, Qiao J, Zhang X, Zhao H, Kang L, Cao L, Zhu P, Miao M

“…Yagang Song,1,2 Shuo Tian,1,2 Zhanzhan Li,1,2 Jinxin Miao,1,2 Mingming Wu,1,2 Tingli Xu,1,2 Xiangxiang Wu,1,2 Jingyi Qiao,1,2 Xialei Zhang,1,3 Hui Zhao,1,2 Le Kang,1,3 Lihua Cao,1,2 Pingsheng Zhu,4 Mingsan Miao1 1Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, People’s Republic of China; 2Collaborative Innovation Center of Research and Development on the Whole Industry Chain of Yu-Yao, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, People’s Republic of China; 3School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, People’s Republic of China; 4College of Chinese Medicine, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, People’s Republic of ChinaCorrespondence: Mingsan Miao, Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, People’s Republic of China, Tel/Fax +86-371-65962546, Email miaomingsan@163.comAbstract: The intratumoral microbiota, an integral part of liver tumors, has garnered significant attention from researchers due to its role in tumor development regulation and impact on cancer treatment. …”
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Adaptive polarimetric optimization for ground deformation monitoring using multi-temporal InSAR with dual-polarization sentinel-1 by Leixin Zhang, Feng Zhao, Yunjia Wang, Jordi J. Mallorqui, Teng Wang, Yuxuan Zhang, Zhongbo Hu, Sen Du, José Fernández

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Wehrl entropy and entanglement complexity of quantum spin systems by Chen Xu, Yiqi Yu, Peng Zhang

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Solar Flare Forecasting Using Hybrid Neural Networks by Dan Xu, Pengchao Sun, Song Feng, Bo Liang, Wei Dai

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Photometric Determination of Unresolved Main-sequence Binaries in the Pleiades: Binary Fraction and Mass-ratio Distribution by Rongrong Liu, Zhengyi Shao, Lu Li

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Cannabidiol Ameliorates Doxorubicin-Induced Myocardial Injury via Activating Hippo Pathway by Dong T, Li J, Liang X, Wang W, Chen M, Yang G, Wu D

“…Tianwei Dong,1 Jinlian Li,2 Xinfang Liang,3 Wang Wang,3 Meichi Chen,4 Guangyuan Yang,5 Dongmei Wu4 1Key Laboratory of Microecology-Immune Regulatory Network and Related Diseases, School of Basic Medicine, Jiamusi University, Jiamusi, Heilongjiang, 154000, People’s Republic of China; 2College of Pharmacy, Jiamusi University, Jiamusi, Heilongjiang, 154007, People’s Republic of China; 3Department of Cardiology, The First Affiliated Hospital of Jiamusi University, Jiamusi, Heilongjiang, 154002, People’s Republic of China; 4School of Basic Medicine, Jiamusi University, Jiamusi, Heilongjiang, 154000, People’s Republic of China; 5Cardiovascular Medicine, The First Affiliated Hospital of Jiamusi University, Jiamusi, Heilongjiang, 154002, People’s Republic of ChinaCorrespondence: Dongmei Wu; Guangyuan Yang, Email dmwu@jmsu.edu.cn; Ygy665@126.comBackground: Doxorubicin (DOX) is a chemotherapeutic agent widely used for cancer treatment and has non-negligible cardiotoxicity. …”
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Photospheric Swirls in a Quiet-Sun Region by Quan Xie, Jiajia Liu, Chris J. Nelson, Robert Erdélyi, Yuming Wang

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Long-Term Outcomes of a Health Information System-Based Feedback Intervention Study of Antimicrobial Prescriptions in Primary Care Institutions: Follow-Up of a Randomized Cross-Ove... by Yan Y, Yang J, Lu Y, Cui Z, Chang Y

“…Yuxing Yan,1,* Junli Yang,1,* Yun Lu,2 Zhezhe Cui,3 Yue Chang1,4 1School of Medicine and Health Management, Guizhou Medical University, Guiyang, Guizhou Province, People’s Republic of China; 2School of Public Health, the Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, Guizhou Province, People’s Republic of China; 3Guangxi Key Laboratory of Major Infectious Disease Prevention and Control and Biosafety Emergency Response, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning, Guangxi Province, People’s Republic of China; 4Center of Medicine Economics and Management Research, Guizhou Medical University, Guiyang, Guizhou Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yue Chang, School of Medicine and Health Management, Guizhou Medical University, 6 Ankang Avenue, GUI ‘An New District, Guiyang, Guizhou Province, People’s Republic of China, Tel/Fax +86-0851-88308118, Email 4567401@qq.com Zhezhe Cui, Guangxi Key Laboratory of Major Infectious Disease Prevention and Control and Biosafety Emergency Response, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, 18 Jinzhou Road, Nanning, Guangxi Province, People’s Republic of China, Tel/Fax +86-0771-2518785, Email czz6997@163.comPurpose: To evaluate the long-term impacts of the feedback intervention on controlling inappropriate use of antimicrobial prescriptions in primary care institutions in China, as a continuation of the previous feedback intervention trial.Methods: After the intervention ended, we conducted a 12-month follow-up study. …”
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Revealing the role of natural killer cells in ankylosing spondylitis: identifying diagnostic biomarkers and therapeutic targets by Yuling Chen, Yan Li, Yuan Xu, Qing Lv, Yuanchun Ye, Jieruo Gu

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