Exploring the Impact of Systemic Inflammatory Regulators on Rosacea Risk: A Bidirectional Mendelian Randomization Analysis by Xue Q, Pan JP, Qian D, Ji J, Fei LY, Yao S, Tan X, Fan WG

“…Qiao Xue,1 Jian Peng Pan,2 Da Qian,3 Jie Ji,4 Lai Yi Fei,1 Sheng Yao,1 Xing Tan,1 Wen Ge Fan1 1Department of Dermatology, Changshu No. 1 People’s Hospital, Changshu Hospital Affiliated to Soochow University, Changshu, Jiangsu, 215500, People’s Republic of China; 2Department of Hand Surgery, Changshu No. 2 People’s Hospital, The Affiliated Changshu Hospital of Nantong University, Changshu, Jiangsu, 215500, People’s Republic of China; 3Department of Burn and Plastic Surgery-Hand Surgery, Changshu No. 1 People’s Hospital, Changshu Hospital Affiliated to Soochow University, Changshu, Jiangsu, 215500, People’s Republic of China; 4Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210000, People’s Republic of ChinaCorrespondence: Qiao Xue, Department of Dermatology, Changshu Hospital Affiliated to Soochow University, Changshu No. 1 People’s Hospital, No. 1 Shuyuan Street, Yushan Town, Changshu, Jiangsu, 215500, People’s Republic of China, Tel +86-13913657476, Email ahjk157@126.com Jian Peng Pan, Department of Hand Surgery, The Affiliated Changshu Hospital of Nantong University, Changshu No. 2 People’s Hospital, 68 South Haiyu Road, Yushan Town, Changshu, Jiangsu, 215500, People’s Republic of China, Tel +86-13814964481, Email 574161036@qq.comObjective: Rosacea is a common chronic inflammatory disorder primarily affecting the face. …”
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Aldehyde Dehydrogenase 2 rs671 Polymorphism is Associated with Susceptibility of Coronary Atherosclerosis in Patients with Hypertension by Hou H, Huang S, Huang W, Huang L, Zhang Z, Liang L

“…Haisong Hou,1 Sina Huang,2 Wenyi Huang,3 Lingmei Huang,1 Zhouhua Zhang,4 Liu Liang5 1Department of Blood Transfusion, Meizhou People’s Hospital, Meizhou, People’s Republic of China; 2Department of Cardiovascular Surgery, Meizhou People’s Hospital, Meizhou, People’s Republic of China; 3Center for Surgical Operation, Meizhou People’s Hospital, Meizhou, People’s Republic of China; 4Center for Cardiovascular Diseases, Meizhou People’s Hospital, Meizhou, People’s Republic of China; 5Department of Laboratory Medicine, Meizhou People’s Hospital, Meizhou, People’s Republic of ChinaCorrespondence: Haisong Hou, Department of Blood Transfusion, Meizhou People’s Hospital, Meizhou, People’s Republic of China, Email houhaisonggd6@163.comObjective: Predisposing factors for coronary atherosclerosis in hypertensive individuals are unclear. …”
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Correlation Between the Ratio of Uric Acid to High-Density Lipoprotein Cholesterol (UHR) and Diabetic Retinopathy in Patients with Type 2 Diabetes Mellitus:A Cross-Sectional Study by Wang L, Liu L, Luo H, Wu Y, Zhu L

“…Leran Wang,1 Lei Liu,2 Huilan Luo,3– 5 Yiling Wu,3– 5 Lingyan Zhu3– 5 1Queen Mary School, Jiangxi Medical College, Nanchang University, Nanchang City, People’s Republic of China; 2Department of Endocrinology, Lu’an Hospital of Anhui Medical University, Lu’an City, Anhui Province, People’s Republic of China; 3Department of Endocrinology and Metabolism, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang City, People’s Republic of China; 4Jiangxi Clinical Research Center for Endocrine and Metabolic Disease, the First Affiliated Hospital of Nanchang University, Nanchang City, People’s Republic of China; 5Jiangxi Branch of National Clinical Research Center for Metabolic Disease, Nanchang City, People’s Republic of ChinaCorrespondence: Lingyan Zhu, Jiangxi Branch of National Clinical Research Center for Metabolic Disease, No. 17, Yongwaizheng Street, Nanchang City, Jiangxi Province, People’s Republic of China, Tel +86-13870690788, Email zly982387@126.comBackground/Objective: Considering the uncertain relationship between high-density lipoprotein cholesterol (HDL-C) and uric acid (UA) with diabetic retinopathy (DR),this study investigates the link between Uric Acid to High-Density Lipoprotein Cholesterol (UHR) and DR in T2DM patients, evaluating its potential for DR diagnosis and early prediction.Study Design and Data Collection: This retrospective study analyzed 1450 type 2 diabetes patients, divided into NDR and DR groups by retinal exams. …”
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Identification of Lauric Acid as a Potent Sodium Channel NaV1.5 Blocker from Compound Chinese Medicine Wenxin Keli by Xie W, Gao J, Liang Y, Huang C, Zhang B, Chen X, Yao X, Nan G, Wu H, Wang Y, Wu L, Wang T, Zhu Y

“…Weiwei Xie,1,* Jiaming Gao,2,* Yingran Liang,1,* Chenxing Huang,3 Boyong Zhang,1 Xiaonan Chen,1 Xi Yao,1 Guo Nan,1 Honghua Wu,1 Yuefei Wang,1 Lin Wu,4 Taiyi Wang,3,5 Yan Zhu1 1State Key Laboratory of Component-Based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, People’s Republic of China; 2Institute of Basic Medical Sciences of Xiyuan Hospital, Beijing Key Laboratory of Pharmacology of Chinese Materia, Beijing, 100091, People’s Republic of China; 3Institute of Acupuncture and Moxibustion, Shandong University of Traditional Chinese Medicine, Jinan, 250355, People’s Republic of China; 4Department of Cardiology, Peking University First Hospital, Beijing, 100034 People’s Republic of China; 5Shandong Key Laboratory of Innovation and Application Research in Basic Theory of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250355, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yan Zhu, State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Beihua South Road, JingHai District, Tianjin, 301617, People’s Republic of China, Tel +86 22 59596168, Email yanzhu.harvard@icloud.com Taiyi Wang, Shandong Key Laboratory of Innovation and Application Research in Basic Theory of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250355, People’s Republic of China, Email wangtaiyi@sdutcm.edu.cnPurpose: The major cardiac voltage-gated sodium channel NaV 1.5 (INa) is essential for cardiac action potential initiation and subsequent propagation. …”
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Risk of All-Cause Mortality in Mild Chronic Obstructive Pulmonary Disease: Evidence From the NHANES III and 2007–2012 by Zou W, Ou J, Wu F, Xiao S, Deng Z, Li H, Wang Z, Tang G, Liu S, Ye D, Zhu D, Hu J, Ran P

“…Weifeng Zou,1,2,* Jie Ou,1,2,* Fan Wu,3,4,* Shan Xiao,5 Zhishan Deng,3 Haiqing Li,3 Zihui Wang,3 Gaoying Tang,3 Shuling Liu,1 Dong Ye,6 Dongshuang Zhu,2 Jinxing Hu,1 Pixin Ran3,4 1State Key Laboratory of Respiratory Disease, Guangzhou Chest Hospital, Guangzhou, People’s Republic of China; 2Department of Pulmonary and Critical Care Medicine, Shufu County People’s Hospital, Kashgar region, Xinjiang, People’s Republic of China; 3State Key Laboratory of Respiratory Disease & Guangzhou Institute of Respiratory Health & National Clinical Research Center for Respiratory Disease & National Center for Respiratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People’s Republic of China; 4Guangzhou National Laboratory, Guangzhou, People’s Republic of China; 5Department of Pulmonary and Critical Care Medicine, Shenzhen Longgang District Central Hospital, Shenzhen, People’s Republic of China; 6Department of Internal Medicine, Guangdong Province Second People’s Hospital, Guangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fan Wu; Pixin Ran, State Key Laboratory of Respiratory Disease & Guangzhou Institute of Respiratory Health & National Center for Respiratory Medicine & National Clinical Research Center for Respiratory Disease & The First Affiliated Hospital of Guangzhou Medical University, 195 Dongfeng Xi Road, Guangzhou, 510120, People’s Republic of China, Email wu.fan@vip.163.com; pxran@gzhmu.edu.cnBackground: It is unclear whether patients with Global Initiative for Chronic Obstructive Lung Disease stage 1 (mild) chronic obstructive pulmonary disease (COPD) have a higher risk of all-cause mortality than participants with normal spirometry results.Methods: We used the data from the National Health and Nutrition Examination Survey (NHANES) III and 2007– 2012, which included participants aged 20– 79 years, to investigate whether patients with mild COPD (whole population and subgroups) have a higher risk of all-cause mortality than participants with normal spirometry. …”
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On subsets of asymptotic bases by Xu, Ji-Zhen, Chen, Yong-Gao

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A Commentary on “Effective Dose of Epidural Hydromorphone for Analgesia Following Caesarean Section in Using Modified Dixon Sequential Method” [Response to Letter] by Liu QQ, Mao M, Lin NH, Xu CY, Li Q, Jiang CS, Feng SW, Yuan HM

“…Qiao-Qiao Liu,1,* Mao Mao,1,* Ning-Hua Lin,2,* Chen-Yang Xu,1,* Qian Li,1 Chang-Shuo Jiang,1 Shan-Wu Feng,1 Hong-Mei Yuan1 1Department of Anesthesiology, Women’s Hospital of Nanjing Medical University, Nanjing Women and Children’s Healthcare Hospital, Nanjing, 210004, People’s Republic of China; 2Department of Anesthesiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, 210008, People’s Republic of China*These authors contributed equally to this workCorrespondence: Shan-Wu Feng; Hong-Mei Yuan, Department of Anesthesiology, Women’s Hospital of Nanjing Medical University, Nanjing Women and Children’s Healthcare Hospital, No. 123, Tianfei Lane, Mochou Road, Nanjing, Jiangsu, People’s Republic of China, Email Shanwufeng666@163.com; yuanhm667@126.com…”
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Crystal structure of N′,N′′′-((1E,1′E)-(propane-2,2-diylbis(1H-pyrrole-5,2diyl))bis(methaneylylidene))di(nicotinohydrazide) pentahydrate, C25H24N8O2·5H2O by Zhou Yi, Zhang Min, Xiong Ying

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Crystal structure of 3,5–di-O-benzoyl-1,2-O-isopropylidene-α–D-ribose, C22H22O7 by Wu Binbin, Chen Guangying, Ding Haixin

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A possible mechanism to alter gyromagnetic factor by Jing-Ling Chen, Xing-Yan Fan, Xiang-Ru Xie

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The crystal structure of 2,4,4-triphenyl-4H-benzo[b][1,4]oxaphosphinin-4-ium bromide – dichloromethane (1/1), C27H22BrCl2OP by Liu Fen, Sun Longgen, Huang Haiyang

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The functions of herpesvirus shuttling proteins in the virus lifecycle by Huijun Cao, Huijun Cao, Huijun Cao, Huijun Cao, Huijun Cao, Mingshu Wang, Mingshu Wang, Mingshu Wang, Mingshu Wang, Mingshu Wang, Anchun Cheng, Anchun Cheng, Anchun Cheng, Anchun Cheng, Anchun Cheng, Bin Tian, Bin Tian, Bin Tian, Bin Tian, Bin Tian, Qiao Yang, Qiao Yang, Qiao Yang, Qiao Yang, Qiao Yang, Xumin Ou, Xumin Ou, Xumin Ou, Xumin Ou, Xumin Ou, Di Sun, Di Sun, Di Sun, Di Sun, Di Sun, Yu He, Yu He, Yu He, Yu He, Yu He, Zhen Wu, Zhen Wu, Zhen Wu, Zhen Wu, Zhen Wu, Xinxin Zhao, Xinxin Zhao, Xinxin Zhao, Xinxin Zhao, Xinxin Zhao, Ying Wu, Ying Wu, Ying Wu, Ying Wu, Ying Wu, Shaqiu Zhang, Shaqiu Zhang, Shaqiu Zhang, Shaqiu Zhang, Shaqiu Zhang, Juan Huang, Juan Huang, Juan Huang, Juan Huang, Juan Huang, YanLing Yu, Ling Zhang, Shun Chen, Shun Chen, Shun Chen, Shun Chen, Shun Chen, Mafeng Liu, Mafeng Liu, Mafeng Liu, Mafeng Liu, Mafeng Liu, Dekang Zhu, Dekang Zhu, Dekang Zhu, Dekang Zhu, Renyong Jia, Renyong Jia, Renyong Jia, Renyong Jia, Renyong Jia

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Why Anemia is Associated with Increased Mortality in AECOPD, What Should We Do? [Letter] by Zhou TT

“…Ting-Ting Zhou Lanzhou University Second Hospital, Lanzhou, People’s Republic of ChinaCorrespondence: Ting-Ting Zhou, Lanzhou University Second Hospital, Cuiyinmen 82, Chengguan District, Lanzhou, Gansu, 730030, People’s Republic of China, Email zhoutt20@126.com…”
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Obstructive Sleep Apnea, Circadian Rhythm Disturbance, Hypertension, and Kidney Stone: An Attractive Quadrangle? [Letter] by He S, Bai Y

“…Sike He, Yunjin Bai Department of Urology, Institute of Urology, West China Hospital, Chengdu, People’s Republic of ChinaCorrespondence: Yunjin Bai, Department of Urology, Institute of Urology, West China Hospital, Chengdu, People’s Republic of China, Email baiyunjin@scu.edu.cn…”
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Evaluating Digital Rehabilitation Outcomes in Chronic Musculoskeletal Conditions Across Non-Obesity, Obesity, and Severe Obesity [Letter] by Zeng X

“…Xuefan Zeng Chongqing Medical University, Chongqing, 400016, People’s Republic of ChinaCorrespondence: Xuefan Zeng, Chongqing Medical University, No. 21, Mid University Town Road, Chongqing, 400016, People’s Republic of China, Email zxfcqmu@163.com…”
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The value of indigenous knowledge for enhancing smallholders’ resilience to climate change and food insecurity: a case study of small-scale irrigation system in Niger by Abdoulkarim Issoufou Kalidou, Gubo Qi, Gabriel Kanuti Ndimbo, Bin Wu

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The Interplay of Aging and PANoptosis in Osteoarthritis Pathogenesis: Implications for Novel Therapeutic Strategies by Liu S, Zhang G, Li N, Wang Z, Lu L

“…Shaoshan Liu,1,* Guifeng Zhang,2,* Nan Li,3 Zheng Wang,4 Liaodong Lu1 1Department of Joint Surgery, Liaocheng Traditional Chinese Medicine Hospital, Liaocheng, 252000, People’s Republic of China; 2Department of Neurology, Liaocheng People’s Hospital and Liaocheng Hospital Affiliated to Shandong First Medical University, Liaocheng, 252000, People’s Republic of China; 3Department of Trauma Orthopedics, Liaocheng Traditional Chinese Medicine Hospital, Liaocheng, 252000, People’s Republic of China; 4Department of Neurosurgery, Liaocheng Traditional Chinese Medicine Hospital, Liaocheng, 252000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zheng Wang, Email zhengyimingdao@gmail.com; Liaodong Lu, Email shuier_226@163.comAbstract: Osteoarthritis (OA) is a common degenerative joint disease characterized by the progressive degradation of articular cartilage, synovial inflammation, and subchondral bone remodeling. …”
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The impact of environmental fees to taxes on total factor productivity of manufacturing enterprises: empirical evidence from China by Jing Huang, Zhaoyang Zhao, Xinjing Yang, Yuhang Tian

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Sintilimab for treating progressive multifocal leukoencephalopathy caused by human polyomavirus 2 virus infection following allogeneic hematopoietic cell transplantation: a case re... by Xuelian Jin, Xushu Zhong, Qinyu Liu, Xinchuan Chen

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Microscopic stress-constrained two-scale topology optimisation for additive manufacturing by Xiaopeng Zhang, Zheng Ni, Akihiro Takezawa, Yaguang Wang, Zhan Kang

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