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41
MicroRNA in Cervical Cancer: OncomiRs and Tumor Suppressor miRs in Diagnosis and Treatment
Published 2014-01-01“…MicroRNAs (miRNAs) are implicated in posttranscriptional regulation of gene expression and in the pathogenic mechanisms of cancer, suggesting their importance in diagnosis and treatment. miRNAs may have roles in the pathogenesis of cervical cancer based on the increases or decreases in several specific miRNAs found in patients with this disease. …”
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42
scATAC-seq generates more accurate and complete regulatory maps than bulk ATAC-seq
Published 2025-01-01“…This has provided great insight into the regulation of gene expression in many cell types in a variety of organisms. …”
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43
Shedding light on DNA methylation and its clinical implications: the impact of long-read-based nanopore technology
Published 2024-12-01“…Abstract DNA methylation is an essential epigenetic mechanism for regulation of gene expression, through which many physiological (X-chromosome inactivation, genetic imprinting, chromatin structure and miRNA regulation, genome defense, silencing of transposable elements) and pathological processes (cancer and repetitive sequences-associated diseases) are regulated. …”
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44
In vivo Study of the Histone Chaperone Activity of Nucleolin by FRAP
Published 2011-01-01“…Nucleolin possesses, in vitro, chromatin co-remodeler and histone chaperone activities which could explain numerous functions of nucleolin related to the regulation of gene expression. The goal of this report was to investigate the consequences of nucleolin depletion on the dynamics of histones in live cells. …”
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45
Conjugacy of two types of phenotypic variability of small-leaved linden
Published 2019-07-01“…According to the authors, asynchronous growth, competition for light in conditions of high solar activity in 2014–2016 compared to the abnormal wet summer of 2017 led to an increase in FA due to destabilization of mechanisms of growth and regulation of gene expression, which contributed to a decrease in the stability of development. …”
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46
Involvement of transposable elements in Alzheimer’s disease pathogenesis
Published 2024-04-01“…Most of these miRNAs originated from LINE retroelements, the pathological activation of which is associated with aging, carcinogenesis, and Alzheimer’s disease, which supports the hypothesis that these three processes are based on the primary dysregulation of transposons that serve as drivers of epigenetic regulation of gene expression in ontogeny.…”
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47
miR-126 and miR-126*: New Players in Cancer
Published 2010-01-01“…These affect various signaling cascades during the progression of neoplastic diseases by the regulation of gene expression on the post-transcriptional level. …”
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48
Role of Hyperbaric Oxygen Therapy in Prostate Tumor Microenvironment and Cancer Stem Cell Niche
Published 2025-01-01“…HBOT is attributed to at least five mechanisms including epigenetic regulation of gene expression, mechanical effects, bacteriostatic effects, hyperoxygenation for carbon monoxide and cyanide poisoning treatment, and restoration from hypoxia. …”
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49
Genome-wide quantification of polycistronic transcription in Leishmania major
Published 2025-01-01“…Lastly, we find evidence for transcriptional pausing of all three RNA polymerase classes, hinting at a possible mechanism of transcriptional regulation.IMPORTANCELeishmania spp. are pathogens of humans and animals and cause one of the most important neglected tropical diseases. Regulation of gene expression in Leishmania but also in the related Trypanosoma is radically different from all eukaryotic model organisms, dispensing with regulated, gene-specific transcription, and relying instead on highly regulated translation. …”
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50
Function of vasohibin-2 and the mechanism of alternative splicing in triple-negative breast cancer
Published 2024-12-01“…Objective·To explore the role of vasohibin-2 (VASH2) in the regulation of proliferation and metastasis of triple-negative breast cancer (TNBC) cells, and explore the mechanism of VASH2 in the occurrence and development of TNBC through regulation of gene expression and alternative splicing.Methods·TCGA-GTEx was used to analyze the expression of VASH2 in TNBC. …”
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51
Promoter engineering with programmable upstream activating sequences in Aspergillus Niger cell factory
Published 2025-01-01“…A wide dynamic range of promoters, particularly strong promoters, are required for fine-tuning the regulation of gene expression to balance metabolic flux and achieve the high yields of desired products. …”
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52
Butyrate Supplementation Improves Intestinal Health and Growth Performance in Livestock: A Review
Published 2025-01-01“…Additionally, butyrate plays a role in the epigenetic regulation of gene expression through histone acetylation, influencing tissue development and immune modulation. …”
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53
Robust genome editing activity and the applications of enhanced miniature CRISPR-Cas12f1
Published 2025-01-01“…Furthermore, we demonstrate that eCas12f1 efficiently induces apoptosis in cancer cells and is compatible with base editing and regulation of gene expression, verifying its high utility and applicability in gene therapy research.…”
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54
Hypermethylation at 45S rDNA promoter in cancers.
Published 2025-01-01“…Hence, clarifying hypo- or hypermethylation of rDNA will unravel its additional cellular functions, including organization of genome architecture and regulation of gene expression, in response to growth signaling, cellular stressors, and carcinogenesis. …”
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55
Role of sirtuins in epigenetic regulation and aging control
Published 2024-04-01“…However, the SIRT influence on the epigenetic regulation of gene expression during the aging process and the development of disorders is one of the most important aspects of maintaining the homeostasis of organs and tissues. …”
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56
Introduction to genetic analysis /
Published 2020Table of Contents: “…Gene Isolation and Manipulation -- 11. Regulation of Gene Expression in Bacteria and Their Viruses -- 12. …”
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57
Effects of polyamines and indole on the expression of ribosome hibernation factors in <i>Escherichia coli</i> at the translational level
Published 2024-03-01“…Polyamines and indole are small regulatory molecules that are involved in the adaptation to stress in bacteria, including the regulation of gene expression. Genes, the translation of which is under the regulatory effects of polyamines, form the polyamine modulon. …”
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58
Different functions of PHF10 isoforms – subunits of the PBAF chromatin remodeling complex
Published 2019-03-01“…Chromatin remodelling multiprotein complexes play an important role in regulation of gene expression in embryogenesis and in the adult organism. …”
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59
MicroRNA-223 Expression Is Upregulated in Insulin Resistant Human Adipose Tissue
Published 2015-01-01“…MicroRNAs (miRNAs) are short noncoding RNAs involved in posttranscriptional regulation of gene expression and influence many cellular functions including glucose and lipid metabolism. …”
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60
Genome-Wide Identification and Expression Profiling of the <i>SPL</i> Transcription Factor Family in Response to Abiotic Stress in Centipedegrass
Published 2024-12-01“…SQUAMOSA promoter-binding protein-like (SPL) transcription factors play a critical role in the regulation of gene expression and are indispensable in orchestrating plant growth and development while also improving resistance to environmental stressors. …”
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