Spidroin-Based Biomaterials in Tissue Engineering: General Approaches and Potential Stem Cell Therapies by Qi Zhang, Min Li, Wenbo Hu, Xin Wang, Jinlian Hu

“…Herein, we present an overview of the recent advances in spider silk protein that fabricate biomaterials for tissue engineering and regenerative medicine. Beginning with a brief description of biological and mechanical properties of spidroin-based materials and the cellular regulatory mechanism, this review summarizes various types of spidroin-based biomaterials from genetically engineered spider silks and their prospects for specific biomedical applications (e.g., lung tissue engineering, vascularization, bone and cartilage regeneration, and peripheral nerve repair), and finally, we prospected the development direction and manufacturing technology of building more refined and customized spidroin-based protein scaffolds.…”
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The Dynamicity of the Oxytocin Receptor in the Brain May Trigger Sensory Deficits in Autism Spectrum Disorder by Claudia Camerino

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3D Printing Manufacturing Techniques, Materials, and Applications: An Overview by D. Srinivasan, M. Meignanamoorthy, M. Ravichandran, V. Mohanavel, S. V. Alagarsamy, C. Chanakyan, S. Sakthivelu, Alagar Karthick, T. Ram Prabhu, S. Rajkumar

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Limb Regeneration in Axolotl: Is It Superhealing? by Stéphane Roy, Mathieu Lévesque

“…A better understanding of these animals' regenerative capacity could lead to major benefits by providing regenerative medicine with directions on how to develop therapeutic approaches leading to regeneration in humans.…”
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Umbilical Cord Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles Modulate Skin Matrix Synthesis and Pigmentation by Kee LT, Foo JB, How CW, Nur Azurah AG, Chan HH, Mohd Yunus MH, Ng SN, Ng MH, Law JX

“…Li Ting Kee,1 Jhi Biau Foo,2– 4 Chee Wun How,5 Abdul Ghani Nur Azurah,6 Hong Hao Chan,5 Mohd Heikal Mohd Yunus,7 See Nguan Ng,8 Min Hwei Ng,1 Jia Xian Law1 1Department of Tissue Engineering and Regenerative Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia; 2School of Pharmacy, Taylor’s University, Subang Jaya, Selangor, Malaysia; 3Digital Health and Medical Advancements Impact Lab, Taylor’s University, Subang Jaya, Selangor, Malaysia; 4Non-Destructive Biomedical and Pharmaceutical Research Centre, Smart Manufacturing Research Institute, Universiti Teknologi MARA Selangor Campus, Puncak Alam, Selangor, Malaysia; 5School of Pharmacy, Monash University Malaysia, Bandar Sunway, Selangor, Malaysia; 6Department of Obstetrics and Gynaecology, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia; 7Department of Physiology, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia; 8Ming Medical Sdn Bhd, Petaling Jaya, Selangor, MalaysiaCorrespondence: Jia Xian Law, Department of Tissue Engineering and Regenerative Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia, Email lawjx@hctm.ukm.edu.myIntroduction: Research has unveiled the remarkable properties of extracellular vesicles derived from mesenchymal stromal cells (MSCs), particularly in promoting wound healing, aiding re-epithelialization, revitalizing aging skin, and inhibiting hyperpigmentation. …”
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Metabolic Modulation and Potential Biomarkers of the Prognosis Identification for Severe Aortic Stenosis after TAVR by a Metabolomics Study by Yanbiao Liao, Chang Liu, Tianyuan Xiong, Mingyue Zhao, Wen Zheng, Yuan Feng, Yijian Li, Yuanweixiang Ou, Zhengang Zhao, Yong Peng, Jiafu Wei, Qiao Li, Wei Meng, Xiaojing Liu, Mao Chen

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Plucked Human Hair Shafts and Biomolecular Medical Research by Kevin Schembri, Christian Scerri, Duncan Ayers

“…The use of stem cells found in hair follicles cells is gaining momentum in the field of regenerative medicine. Furthermore, current diagnostic and clinical applications of plucked hair follicles include their use as autologous and/or three-dimensional epidermal equivalents, together with their utilization as surrogate tissue in pharmacokinetic and pharmacodynamics studies. …”
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Perspectives for Clinical Translation of Adipose Stromal/Stem Cells by Mimmi Patrikoski, Bettina Mannerström, Susanna Miettinen

“…Adipose stromal/stem cells (ASCs) are an ideal cell type for regenerative medicine applications, as they can easily be harvested from adipose tissue in large quantities. …”
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Genetically Engineered Islets and Alternative Sources of Insulin-Producing Cells for Treating Autoimmune Diabetes: Quo Vadis? by Feng-Cheng Chou, Shing-Hwa Huang, Huey-Kang Sytwu

“…In addition, for an alternative source of pancreatic β-cell replacement therapy, the ex vivo generation of insulin-secreting cells from diverse origins of stem/progenitor cells has become an attractive option in regenerative medicine. This paper focuses on the genetic manipulation of islets during transplantation therapy and summarizes current strategies to obtain functional insulin-secreting cells from stem/progenitor cells.…”
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From heparan glycobiology to stem cell therapy: a historical perspective by Victor Nurcombe

“…Translational avenues include the selection and biochemical tuning of heparan sugars as nanoscale scaffolds that support cell signaling for specific applications in tissue engineering and regenerative medicine. If the important progress in the past 40 years is any guide, the field of glycobiology is about to enter a golden era, with realistic prospects for glycotherapies that encompass a range of clinical disorders.…”
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Pulsed Electromagnetic Field Therapy as a Complementary Alternative for Chronic Pelvic Pain Management in an Interstitial Cystitis/Bladder Pain Syndrome Patient by Tyler L. Overholt, Christina Ross, Robert J. Evans, Stephen J. Walker

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Analysis of Embryoid Bodies Derived from Human Induced Pluripotent Stem Cells as a Means to Assess Pluripotency by Steven D. Sheridan, Vasudha Surampudi, Raj R. Rao

“…Human induced pluripotent stem cells (hiPSCs) have core properties of unlimited self-renewal and differentiation potential and have emerged as exciting cell sources for applications in regenerative medicine, drug discovery, understanding of development, and disease etiology. …”
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Mesenchymal Stem and Progenitor Cells in Regeneration: Tissue Specificity and Regenerative Potential by Rokhsareh Rohban, Thomas Rudolf Pieber

“…There have been many elegant studies investigating the impact of MSC in regenerative medicine. This review provides compact information on the role of stem cells, in particular, MSC in regeneration.…”
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Densely vascularized thick 3D tissue shows enhanced protein secretion constructed with intermittent positive pressure by Misako Katsuura, Jun Homma, Yuhei Higashi, Hidekazu Sekine, Tatsuya Shimizu

“…This approach demonstrates promise for fabricating functional, transplantable, and thick tissues with dense vascularization and a high capacity for protein secretion, paving the way for novel applications in regenerative medicine.…”
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miRNA in blood-brain barrier repair: role of extracellular vesicles in stroke recovery by Vojtech Sprincl, Vojtech Sprincl, Nataliya Romanyuk

“…Recent advances in regenerative medicine suggest that mesenchymal stem cells (MSCs) derived extracellular vesicles (EVs) show promise for restoring BBB integrity. …”
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Recent Advances in Carbon Nanotubes for Nervous Tissue Regeneration by Carlos Redondo-Gómez, Rocío Leandro-Mora, Daniela Blanch-Bermúdez, Christopher Espinoza-Araya, David Hidalgo-Barrantes, José Vega-Baudrit

“…Regenerative medicine has taken advantage of several nanomaterials for reparation of diseased or damaged tissues in the nervous system involved in memory, cognition, and movement. …”
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Differentiation of Human Embryonic Stem Cells into Neuron, Cholinergic, and Glial Cells by Kimia Hosseini, Emilia Lekholm, Aikeremu Ahemaiti, Robert Fredriksson

“…Derived from the inner cell mass of blastocysts in early embryonic development, the cell self-renewal ability makes them a great tool for regenerative medicine, and there are different protocols available for maintaining hESCs in their undifferentiated state. …”
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The Integration of Nanotechnology and Biology for Cell Engineering: Promises and Challenges by Uma Maheswari Krishnan, Swaminathan Sethuraman

“…Conclusion: This review provides information about the factors influencing tissue engineering, namely geometry, chemistry, mechanics and cells, and the emerging concepts that may well represent the future of regenerative medicine. Electrospinning techniques and their variants, self-assembly, cell-printing techniques and cell sheet engineering, have all been elaborated in detail. …”
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Cissus quadrangularis: A comprehensive review as an emerging biomaterial for periodontal regeneration by H Nilofer Farjana, G. Mohan Valiathan

“…Periodontal tissue engineering is surging in regenerative medicine. It is a triad that includes cells, scaffolds, and growth factors that help to form newly aligned functional periodontal structures. …”
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Applications of Amniotic Membrane in Ophthalmology – New Perspectives in the Treatment of Eye Diseases by Larysa Krajewska-Węglewicz

“…Amniotic membrane, a natural protective barrier surrounding the fetus, possesses unique biological properties, making it a promising tool in regenerative medicine. It contains pluripotent cells, collagen, anti-inflammatory cytokines, and growth factors. …”
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