Applications of Neuroimaging to Disease-Modification Trials in Alzheimer’s Disease by Adam S. Fleisher, Michael Donohue, Kewei Chen, James B. Brewer, Paul S. Aisen, the Alzheimer’s Disease Neuroimaging Initiative

“…Clinical outcome measures typically used in therapeutic trials have unfortunately proven to be relatively variable and somewhat insensitive to change in this slowly progressive disease. For this reason, development of surrogate biomarkers that identify significant disease-associated brain changes are necessary to expedite treatment development in AD. …”
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Examination of memory and culture based on the architectural facade: Facadism at Beyoğlu district by Aliye Rahsan Karabetca, Sedef Sav

“…This city, which has undergone many changes due to social, political, and cultural reasons, has begun to lose its many important values day by day. …”
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Determination of microbiological quality characteristics of bonito fish (sarda sarda) stored at different temperatures by Duygu Balpetek Külcü

“…From a microbiological point of view, quality is an important issue for aquatic products because of their easy degradability. For this reason, all phases starting from the fish hunting stages to the procurement of the consumer must be carefully examined and inspected.…”
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Determining the Climate Classes and Producing GIS-Based Climate Boundary Maps of Bartın Province by Hülya Keskin Çıtıroğlu, Deniz Arca

“…For this purpose, in this study, the creation of the climate boundary maps of Bartın province (Amasra, Kurucaşile, Merkez District and Ulus) was taken as a basis, based on the need to form a basis for planning. For this reason, the water balance of each district station was calculated using measurement data from four meteorological stations located in the districts of Bartın province for the last thirty years, utilizing the Thornthwaite climate classification method. …”
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A Challenge for Diagnosing Acute Liver Injury with Concomitant/Sequential Exposure to Multiple Drugs: Can Causality Assessment Scales Be Utilized to Identify the Offending Drug? by Roxanne Lim, Hassan Choudry, Kim Conner, Wikrom Karnsakul

“…Drug-induced hepatotoxicity most commonly manifests as an acute hepatitis syndrome and remains the leading cause of drug-induced death/mortality and the primary reason for withdrawal of drugs from the pharmaceutical market. …”
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Mechanical Properties of Steel Fiber-Reinforced Concrete by Vibratory Mixing Technology by Yuanxun Zheng, Xiaolong Wu, Guangxian He, Qingfang Shang, Jianguo Xu, Yikai Sun

“…Up to now, steel fiber-reinforced concrete was usually produced by the traditional mixing method. For the reason of uniform distribution of fiber, the reinforcement of mechanical properties of concrete was inadequately performed. …”
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Application of Electro-Fenton Technology to Remediation of Polluted Effluents by Self-Sustaining Process by Maria Ángeles Fernández de Dios, Olaia Iglesias, Marta Pazos, Maria Ángeles Sanromán

“…The electro-Fenton technology is an advanced oxidation process that is efficient for the degradation of organic pollutants, but it suffers from the high operating costs due to the need for power investment. For this reason, in this study microbial fuel cells (MFCs) were designed in order to supply electricity to electro-Fenton processes and to achieve high treatment efficiency at low cost. …”
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Frailty among Older Adults Who Developed Acute Coronary Syndrome during Hospitalization for Noncardiac Illness and Their Outcome: A Prospective Observational Study by Arun David, Priya Vijayakumar, M Vijayakumar

“…Results: Majority of them had non-ST elevation ACS (90.2%) in Group II, and acute kidney injury (27.1%) was the most common reason for admission. Optimum management was given to a lesser extent due to the current clinical condition of these patients. …”
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Philosopher avec les enfants dès l’école élémentaire grâce à la littérature : analyse d’un corpus de trois années d’ateliers de philosophie en cycle 3 by Edwige Chirouter

“…Deleuze's word, a child is the "idiot" par excellence, the one who asks about the reason for, and essence of, all things with the utmost naiveté and intensity. …”
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The Numbers Line Media to Improve the Ability of the Students In Calculating Integer Operation by Muhammad Sholahuddin Arif, Kholifah Kholifah

“…The interested thing to study on the teaching and learning strategies in elementary school is the understanding of the development of the learners at once the uniqueness that is required the teachers on identifying suitable actions (behavior in children) as a goal that can be achieved in the teaching, the activities and the learning experiences for certain age groups, and the evaluation system to be used. Therefore, this reason become strong in order to the teaching system that was developed by the teacher is expected to be increasingly able to serve the requirements of the individual learner (individually guided education) and the teaching become interested and meaningful for children. …”
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Manufacturing of Human Umbilical Cord Mesenchymal Stromal Cells on Microcarriers in a Dynamic System for Clinical Use by Florian Petry, J. Robert Smith, Jasmin Leber, Denise Salzig, Peter Czermak, Mark L. Weiss

“…For a large expansion of these cells, we performed a process transfer from static culture to a dynamic system. For this reason, a microcarrier selection out of five microcarrier types was made to achieve a suitable growth surface for the cells. …”
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Facing a blind alley - Experiences of stress-related exhaustion: a qualitative study by Lilas Ali, Andreas Fors, Inger Ekman, Sara Alsén

“…In Sweden, stress-related mental illness is currently the most frequent reason for sick leave.Objective This study aimed to explore patients’ experiences of stress-related exhaustion.Design A qualitative study with interview data analysed using a phenomenological hermeneutic method.Setting Participants were selected from public primary healthcare centres in a larger city in western Sweden.Participants Seven women and five men on sick leave from work due to stress-related exhaustion were included in the study.Findings Stress-related exhaustion was experienced as a loss of access to oneself and one’s context and feelings of being trapped and lost in life. …”
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Features of metropolitan area governance models by Yu. V. Pavlov, G. A. Khmeleva

“…These capabilities can be expressed through the description of the features of the models.For a large-scale description of the features of models, it is necessary to form groups of features, characterize each feature, compare the models according to the degree of its manifestation, and, if possible, explain the reason for the differences. The article investigates research papers within the framework of the theory of municipal reformers, the theory of public choice, in particular on the issues of centralization / decentralization of municipalities, intermunicipal cooperation, the efficiency of the economy of the public sector. …”
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DYSPHEMISM USED IN DEADPOOL MOVIE PAPER TITLE by Maria Ayu Pretty Sitanggang, Eddy Setia, Rohani Ganie

“…Dysphemism in Deadpool is problematized in its home country, i.e. the United States, due to its excessive occurrences. For this reason, this study aims at 1) to find out the types of dysphemism which illuminate the uses of dysphemism, and 2) revealing the functions which explain why the characters utilize such dysphemistic words. …”
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Collector and philatelic press in the RSFSR/USSR during the first half of the 1920s: From pluralism to monopolism by A.V. Yakub, N.V. Yakub

“…The publishing development and the editorial attitudes in the collector periodicals of that time were determined by the Soviet reality and reflected it. For this reason, the Soviet collector periodicals, including philatelic magazines, serve as an invaluable source of evidence of the growing pressure produced by the party policies in propaganda, agitation, and publishing industry. …”
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Evaluation of chitosan based pretreatment for cotton and linen dyeing with direct dyes and reactive dyes by Mohammad Toufiqul Hoque, Tian Benrui, Thomas Grethe, Boris Mahltig

“…This good affinity is the reason for good washing and rubbing fastness. Chitosan is a bio-based polymer gained by the deacetylation of chitin. …”
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A Fuzzy Ecosystem Benchmarking for Crowdfunding in Transport Sector by Gargi Pant Shukla, Santosh Kumar, Mukesh Kumar, Ankit Kumar, Manoj Chhetri

“…Such relation of all variables is the precise reason for storm growth in the field. “No or Low in regulation” is one of the most significant factors to the growth and acceptance of this innovative fundraising method by common investors but cannot be controlled directly by the associated crowdfunding members in the transport industry.…”
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Functional analysis of school refusal: An exploratory study in the Indian context by Arun Singh Yadav, Kiragasur Madegowda Rajendra, Lakshmi Sravanti, John Vijay Sagar Kommu, Shekhar Seshadri, Satish Chandra Girimaji

“…Results: Anxiety in social/evaluative situations associated with tangible rewards at home was the predominant primary reason for school refusal in this sample. There was a significant statistical association between functions of school refusal and scholastic performance, psychiatric diagnosis, and family stressors. …”
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On the issue of producing doubled haploids of table beet (<i>Beta vulgaris</i> L. var. <i>conditiva</i> Alef.) (a review) by A. M. Zaretsky, A. B. Kurina, D. V. Sokolova

“…Heterosis breeding of table beet in Russia is developed insufficiently. One of the reasons is the lack of a well-studied homogeneous linear material. …”
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Conductivity Insights Into the Carbon Nanotubes Mobility Restricted by the Long‐Branched Chains During the Thermal Annealing, Fast Shear Flow and Melt to Solid Cooling Process by Jixiang Li, Abderrahim Maazouz, Khalid Lamnawar

“…The harder movement of CNTs inside LCB PPH matrix may be the main reason. This also can be reflected by the conductivity evolution during slow cooling process where a decrease‐then‐increase (DTI) phenomenon is found for PPC/CNTs systems due to the rebuilding of CNTs conductivity network after crystallization. …”
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