A cost-effectiveness analysis of sotorasib as second-line treatment for patients with KRAS-G12C-mutated metastatic non-small cell lung cancer (mNSCLC) in Switzerland by Tämer El Saadany, Judith Lupatsch, Michael Mark, Michaela Barbier, Tarun Mehra, Matthias Schwenkglenks, Roger von Moos

“…These factors suggest that it would be reasonable to price it at approximately one-quarter of the assumed cost in the UK. …”
Get full text

Discussion Paper for the Foundation for the Rights of Future Generations - The housing crisis as a problem of intergenerational justice: The case of Germany by Elena Lutz

“…Governmental programmes, such as the first-time homebuyers plan in Canada, can help young individuals to obtain resources for the down payment on a mortgage, thereby improving their chances to be able to obtain a mortgage at a reasonable interest rate.   3. Measures to increase housing supply. …”
Get full text

Development of a new data management system for the study of the gut microbiome of children who are small for their gestational age by Felix Manske, Magdalena Durda-Masny, Norbert Grundmann, Jan Mazela, Monika Englert-Golon, Marta Szymankiewicz-Bręborowicz, Joanna Ciomborowska-Basheer, Izabela Makałowska, Anita Szwed, Wojciech Makałowski

“…By providing users with the MetagenomicsDB backend which constitutes the major part of the system, we ensure that custom development can be finished in a reasonable amount of time. We report our endeavors in order to motivate the application of data management systems at the scale of single studies in microbiome research.…”
Get full text

Experiences of Oral Corticosteroid Use and Adverse Effects: A National Cross-Sectional Survey of People with Asthma by Jones AW, McDonald VM, McLoughlin RF, Vella TM, Flynn AW, Blakey JD, Wolfenden L, Hew M, Upham JW, Thomas D, Bardin P, Holland AE

“…Survey free-text responses were coded to the Theoretical Domains Framework (TDF) to elicit determinants of OCS use.Results: 1808 people with asthma participated between 3 and 16 May 2022. Most common reasons for using OCS were severe asthma symptoms (40%), doctor prescription (38%) or asthma action plan recommendations (20%). …”
Get full text

A visual walkthrough of robotic partial mesorectal excision using the Versius surgical system by Amro Mureb

“…Several publications have shown that partial excision of the mesorectum, also called tumour-specific mesorectal excision (TSME), with the division of mesorectum 5 cm below the tumour could be a reasonable approach although total mesorectal excision (TME) is still considered the gold standard for all rectal cancer in many studies. …”
Get full text

Exploring the benefits and prescribing informations of combining East Asian herbal medicine with conventional medicine in the treatment of rheumatoid arthritis: A systematic review... by Hee-Geun Jo, Jihye Seo, Eunhye Baek, Donghun Lee

“…In particular, given that the ACR index integrates multiple aspects of RA patients, the results are expected to provide valuable complementary decision support for the management of RA patients who do not respond well to CM therapy, both for medical and economic reasons. Additionally, the key herbs derived through the multifaceted analysis, which actively reflect clinicians' implicit preferences for prescribing EACMs, may serve as important hypotheses for further research and clinical application. …”
Get full text

Investigation on willingness of psychiatric nurses to engage in dementia nursing and influencing factors analysis (精神科护士从事失智症护理工作意愿调查及影响因素分析)... by GU Liqin (顾丽琴), JI Caifang (季彩芳), TANG Xiaofang (唐晓芳)

“…Motivation and interest in dementia care was main influencing factors of willingness to engage in dementia nursing. The main reasons for unwilling to engage in the nursing work of patients with dementia included: difficulty in communication with elderly dementia patients, high nursing risk and high incidence of accidents, complicated physical diseases associated with the elderly, rapid changes in the disease condition, complex illness, lack of professional ability, lack of sense of value and their own development direction, uneven pay and income. …”
Get full text

Research on time–frequency characteristics of electromagnetic signals from coal and rock blasting based on DBO-VMD filtering by Litao WANG, Liming QIU, Menghan WEI, Dazhao SONG, Rentao GOU, Lin LIU, Shiqiang ZHONG, Tianyi XIE

“…When comparing electromagnetic signals processed by the DBO-VMD and empirical mode decomposition (EMD), the DBO-VMD effectively avoids modal aliasing and provides more reasonable center-frequency distributions. After applying a consistent noise reduction process, the DBO-VMD model shows superior performance over EMD. …”
Get full text

Corporate Social Responsibility's Influence on Product Innovation: Spotlight on the Mediating Role of Employer Branding (A Case Study of Medium and Large Manufacturing Firms in Bus... by zahra hajizadeh, Ebrahim Rajabpour, Heidar Ahmadi, Majid Esmaeilpour

“…Put differently, firms focusing on socially responsible actions tend to innovate more in products and procedures for various reasons, primarily because the orthodox approach is no longer effective. …”
Get full text

State-of-the-art of loading and unloading tests for glaucoma: potentialities and informative value by O.S. Myakonkaya, A.S. Sarkisyan, A.V. Seleznev, A.V. Kuroyedov, I.R. Gazizova

“…Unloading tests are reasonable if the IOP level is the upper normal lim it or slightly higher. …”
Get full text

Sensory acceptability of buffalo meat compared to beef by Luis A. de la Cruz-Cruz, Cristian Larrondo-Cornejo, Patricia Roldán-Santiago, René Rodríguez-Florentino

“…The panelist highlighted various reasons why buffalo meat is not commonly consumed, such as there is no information on buffalo meat (93.42%/n=71), there are not many products made with buffalo meat (60.52%/n =46), and that it is not available at supermarkets (73.69%/n=56). …”
Get full text

Menciptakan Layanan Pengawasan Ketenagakerjaan secara Profesional, Moderm dan Bermartabat Berbasis Teknologi Digital by Yeni Nuraeni, Nurlia Rahmatika, Firdausi Nuzula, Faizal Amir Nasution

“…Abstract The limited human resources of labor inspection and the geographical condition of Indonesia, which is an archipelago, are the main reasons for the importance of using digital technology in the implementation of labor inspection. …”
Get full text

Three-dimensional omnidirectional characterization methods of rock anisotropic wave velocity and acoustic emission location optimization by Shengjun MIAO, Wenxuan YU, Mingchun LIANG, Pengjin YANG, Conghao LI, Zejing LIU

“…The location error for siltstone is greater than that for marble due to three primary reasons. First, siltstone exhibits high porosity, resulting in unstable and noisy acoustic emission signals, which complicate the extraction of the received signals. …”
Get full text

Influence of mental workload on professional identity of nursing students who were born between 1995 and 1999 (“95后”护生工作心理负荷对职业认同的影响) by LU Sheng (陆晟), WANG Zhenmeng (王振猛), SHENG Yuehong (盛月红)

“…Multiple regression analysis showed that occupation identity was influenced by multiple issues including place of residence、reasons of choosing the nursing specialty, degree of satisfaction with teacher and willingness to engage in nursing after graduation. …”
Get full text

Sentiments of Individuals with Interstitial Cystitis/Bladder Pain Syndrome Toward Pentosan Polysulfate Sodium: Infodemiology Study by Yulin Hswen, Qiuyuan Qin, Pressley Smith, Alison Swierczynski, Stuart Bauer, Erika Ladson, Amanda Leigh Garrett, Catherine A Brownstein

“…Sentiment analysis and percentages of negative, positive, and neutral sentiment for PPS discussions encompassing each topic was conducted using VADER (Valence Aware Dictionary for Sentiment Reasoning). Topic modeling was conducted using latent Dirichlet allocation. …”
Get full text

Pemanfaatan Fuzzy Logic dan Hill Climbing untuk Optimasi Pengelolaan Tempat Pengolahan Sampah Reduce-Reuse-Recycle (TPS 3R) pada Dinas Lingkungan Hidup (DLH) DKI Jakarta by Ramadana Arbi, Meinarini Catur Utami, Qurrotul Aini

“…The 3R TPS is still functionally not maximum way to be used as inadequate facilities such as quality degradation on organic counter, and there is no mechanical separation place and its room. With that reasons, the 3R TPS needs to be financial supported.  …”
Get full text

Rapid inference of antibiotic susceptibility phenotype of uropathogens using metagenomic sequencing with neighbor typing by Amanda C. Carroll, Leanne Mortimer, Hiren Ghosh, Sandra Reuter, Hajo Grundmann, Karel Brinda, William P. Hanage, Angel Li, Aimee Paterson, Andrew Purssell, Ashley Rooney, Noelle R. Yee, Bryan Coburn, Shola Able-Thomas, Martin Antonio, Allison McGeer, Derek R. MacFadden

“…Numerous antibiotic classes could reasonably be reconsidered empiric therapy by shifting empiric probabilities of susceptibility across relevant treatment thresholds. …”
Get full text

Agro-Ecological Assessment of Lands in Behshahr County for Lentil (Lens culinaris Medik.) Cultivation by Karim Reyahi, Hossein Kazemi, Afshin Soltani, Fardin Sadeghzadeh

“…In general, two classes of high suitability and suitability comprise about 56.97% of the area. One of the main reasons for this result was the suitable soil fertility, rainfall, and topographical conditions. …”
Get full text

Hubungan Electronic Customer Relationship Management (E-Crm) Terhadap Loyalitas Pasien Di Rumah Sakit: Tinjauan Pustaka by Sabrina Aulia Rahma, Holipah Holipah, Harun Al Rasyid, Fida Rahmayanti

“…Increased competition between hospitals is one of the reasons for the need for marketing strategy innovation to maintain the loyalty of hospital patients as consumers. …”
Get full text

Loose cigarette purchase and adolescent smoking in Indonesia: a mixed-methods study by Vid Adrison, Dian Kusuma, Gea Melinda, Fariza Zahra Kamilah, Syifa Rizki Amelia, Sofwatun Nida

“…Our qualitative findings further reported that affordability and accessibility were the main reasons that encouraged current student smokers to opt for loose cigarettes over other types of cigarettes (packs, cartons or rolled tobacco). …”
Get full text