The sphingosine‐1‐phosphate signaling pathway (sphingosine‐1‐phosphate and its receptor, sphingosine kinase) and epilepsy by Lin Wang, Qingxia Kong, Xinyi Leng, Howan Leung, Yang Li

“…Here, we summarize and analyze the role of the S1P signaling pathway in epilepsy, provide a basis for finding potential therapeutic targets and/or epileptogenic biomarkers, analyze the reasons for these controversies, and put forward our opinions. …”
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Self-sampling and self-testing for HIV at a commercial and community-based test provider in the Netherlands: user preferences and usability by I. J. M. Willemstein, O. Shobowale, A. M. Żakowicz, H. Bos, E. L. M. Op de Coul

“…Women and heterosexual men were more likely to buy an HIVSS/ST as part of a combination Sexually Transmitted Infections (STI) test package. Overall, main reasons for choosing HIVSS/ST were saving time (42%), anonymity (36%) and not having to talk to a GP (35%). …”
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Investigation of the Prevalence and Diagnosis of Chronic Obstructive Pulmonary Disease in a Group of Elderly Individuals Residing in an Island Area of Ningbo by Wei Sheng, Youchang Huang, Zaichun Deng, Hongying Ma

“…COPD-positive individuals then completed a questionnaire surveying the status of diagnosis and treatment of COPD and the reasons for missed diagnosis and treatment. The data were collated and analyzed using SPSS version 22.0 (IBM Corporation, Armonk, NY, USA). …”
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Comparative analysis of machine learning approaches for predicting the risk of vaginal laxity by Hongguo Zhao, Peng Liu, Fei Chen, Mengjuan Wang, Jiaxi Liu, Xiling Fu, Hang Yu, Manman Nai, Lei Li, Xinbin Li

“…The XGBoost model has the more comprehensive and reasonable performance among the four prediction models, which can accurately distinguish between healthy, mild VL, as well as moderate VL and severe VL, which can assist doctors in diagnosing persons’ conditions more accurately, devising personalized treatment plans, avoiding unnecessary surgeries, reducing persons’ psychological stress, improving patient compliance and treatment outcomes, thus enhancing overall treatment results.…”
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Fructosamine measurement for diabetes mellitus diagnosis and monitoring: a systematic review and meta-analysis protocol by Andre Pascal Kengne, Eugene Sobngwi, Jean Jacques N Noubiap, Jobert Richie N Nansseu, Joël Fokom-Domgue, Eric V Balti

“…Fructosamine has not gained as much popularity as glycated haemoglobin (HbA1c) for diabetes mellitus (DM) control monitoring, and the related underlying reasons remain unclear. We aim to search for and summarise available evidence on the accuracy of fructosamine measurements to diagnose and monitor DM.Methods and analysis This systematic review will include randomised control trials, controlled before-and-after studies, time series designs, cohort studies, case–control studies and cross-sectional surveys reporting the diagnosis and/or monitoring of DM (type 1 DM, type 2 DM and gestational DM) with fructosamine compared with other measures of glycaemia (fasting glucose, oral glucose tolerance test, random glucose, HbA1c), without any language restriction. …”
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Clinicopathological Review of 547 Bulbar Enucleations in Hungary (2006–2017) by Gábor Tóth, Nóra Szentmáry, Gábor László Sándor, Béla Csákány, Erika Maka, Jeannette Tóth, Zsuzsanna Antus, Milán Tamás Pluzsik, Achim Langenbucher, Zoltán Zsolt Nagy, Olga Lukáts

“…Clinical immediate enucleation indications were tumours (46.1%), atrophia or phthisis bulbi (18.5%), infection or inflammation (18.5%), painful blind eye due to glaucoma (11.2%), acute trauma (3.7%), threatening or spontaneous perforation (1.3%), cosmetic reasons (0.5%), and expulsive bleeding (0.4%). Conclusions. …”
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Application of the <italic>International Classification of Functioning，Disability and Health Rehabilitation Set</italic> in Rehabilitation of Patients with Knee Osteoarthritis in t... by YAO Dong, HE Yiqi, ZHANG Qin, LIU Changhua, LI Taibiao, YAO Caiming, WANG Xiangfeng, WANG Qinfeng, HU Hongjun

“…ObjectiveTo explore the feasibility of the International Classification of Functioning, Disability and Health Rehabilitation Set (ICF-RS) in evaluating the overall functional level, rehabilitation treatment effect, and the relationship between rehabilitation efficacy and cost-effectiveness of patients with knee osteoarthritis (KOA) in the northwest Gobi region.MethodsA total of 50 patients with KOA who were hospitalized in the Acupuncture and Moxibustion Department of Jimsar County Hospital of Traditional Chinese Medicine from March 2022 to March 2023 were selected. Due to reasons such as patients' own comprehension deviation and low assessment compliance, 8 cases were discontinued or dropped out, and finally 42 cases were included. …”
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Diversity of lithophytic moss species in karst regions in response to elevation gradients. by Yalin Jin, Xiurong Wang

“…The findings can enrich the theory of the distribution pattern of lithophytic moss species diversity at distinct elevation gradients in karst regions, and serve a scientific and reasonable reference for restoring rocky desertification and protecting biodiversity there.…”
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A high fraction of inspired oxygen does not mitigate atelectasis-induced lung tissue hypoxia or injury in experimental acute respiratory distress syndrome by Kentaro Tojo, Takuya Yazawa

“…Therefore, it is possible that excessively low FIO2 may enhance hypoxia-induced inflammation in atelectasis, and raising FIO2 to an appropriate level may be a reasonable strategy for its mitigation. In this study, we investigated the effects of different FIO2 levels on alveolar tissue hypoxia and injury in a mechanically ventilated rat model of experimental ARDS with atelectasis. …”
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Risk of Selected Fetal Adverse Pregnancy Outcomes at Advanced Maternal Age: A Retrospective Cohort Study in Debre Markos Referral Hospital, Northwest Ethiopia by Bikila Tefera Debelo, Melaku Hunie Asratie, Abayneh Aklilu Solomon

“…Today, women postpone pregnancy due to different socioeconomic and personal reasons. However, there was limited evidence on fetal adverse outcomes’ association with pregnancy at an advanced maternal age in Ethiopia and particularly in the study area. …”
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Chingi-tura in the History of the Tyumen Khanate by Maslyuzhenko D.N., Ryabinina E.A.

“…Only after 1431, in the time of Abu-l-Khair, did Chingi-tura receive the status of a throne place (Tyumen of Russian sources) which is a reasonable basis to refer to the state as the Tyumen Khanate. …”
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Tumor tissue samples collection for scientific research in morphology and molecular oncology by O. R. Khabarov, B. D. Seferov, K. A. Aliev, D. V. Zima, E. P. Golubinskaya, E. Yu. Zyablitskaya

“…The total number of tissue samples is n = 7000.Results. It is reasonable to gather the collection in a pathomorphological laboratory according to the profile of the medical institutions, which has a sufficient volume of incoming target material and specialized morphologists to verify tumors of a given localization. …”
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Multi-Scale Spatio-Temporal Evolution Characteristics and Influencing Factors of Jobs-Housing Balance in Shenzhen in the Context of COVID-19 Pandemic by Duan Lipeng, Gu Zhihui, Zhang Yan, Liu Qian

“…This trend is most prominently manifested at the 1 km grid scale across the three research scales. (3) Spatial heterogeneity affected the evolution trends of jobs-housing relationships before and during the pandemic, with public transportation accessibility and socioeconomic characteristics of residents being the main reasons for differentiation in evolutionary types. …”
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Association between maternal gestation weight gain and preterm birth according to pre-pregnancy body mass index and HbA1c by Xiaoxiao Zhang, Binbin Yin, Kaiqi Wu, Lei Fang, Yan Chen

“…Similar results were observed in women with normal pp-BMI.Conclusions There was a significant association between GWG and the risk of PTB, but the risk varied by pp-BMI and HbA1c levels. Reasonable weight gain during pregnancy is essential to prevent PTB. …”
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Spatiotemporal Variations of PM2.5 and O3 Relationship during 2014–2021 in Eastern China by Yasong Li, Tijian Wang, Qin’geng Wang, Yawei Qu, Hao Wu, Min Xie, Mengmeng Li, Shu Li, Bingliang Zhuang

“…These findings serve as a valuable reference for formulating a reasonable collaborative control scheme for these two pollutants.…”
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The response of soil microbial community to application of organic amendment to saline land by Peifei Cong, Peifei Cong, Peifei Cong, Pengfei Huang, Zhisheng Huang, Zhisheng Huang, Zhisheng Huang, Zhisheng Huang

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Payment Reforms for Prehospital Care Services in a Middle Income Country: Assessing Implementation and Patient Outcomes Using a Mixed-Methods Approach by Paibul Suriyawongpaisal, Samrit Srithamrongsawad, Pongsakorn Atiksawedparit, Khanisthar Phooseemungkun, Krongkan Bunchaiyai, Thanita Thongtan

“…The aims of this study were to (1) assess the effects of direct-pay system in terms of (a) timeliness of reimbursement to EMS agencies, (b) changes in clinical care processes, and (c) the outcomes of patient care as compared to previous system; (2) identify the reasons for or against EMS agencies to participate in direct-pay system mechanisms; (3) identify the emerging issues with potential to significantly further the advancement of EMS systems. …”
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Feature Selection for Physical Activity Prediction Using Ecological Momentary Assessments to Personalize Intervention Timing: Longitudinal Observational Study by Devender Kumar, David Haag, Jens Blechert, Josef Niebauer, Jan David Smeddinck

“…ConclusionsA small set of EMA-based features like self-efficacy, stress, planning, and perceived barriers can be enough to predict PA reasonably well and can thus be used to meaningfully tailor JITAIs such as sending well-timed and context-aware support messages.…”
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Rahasia Tartib Surah dan Ayat Al-Quran dari Unsur Bilangan (Kajian Pemikiran Izza Rohman) by Sri Pujilestari, Weka Dwi Kartika, Azah Lailaturrosidah, Abdussakir, Muhammad

“…The results showed that the order of the surahs and verses of the Qur'an became the inspiration and object of study whose different sequences had basic reasons. The discovery of the regularity and harmony of the number of surahs and verses in the Al-Quran. …”
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Mechanisms and thresholds of land use affecting surface water quality in Hangzhou City’s residential areas by Qianhu Chen, Jinye Huang

“…The conclusions are as follows: (1) Surface water pollution varied among different types of residential areas, with NH3-N and TP being the most significantly impacted indicators of water quality. (2) The development of set density and fragmentation of green space were the major reasons for the increase in pollutant concentration. …”
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