Paediatric nephroblastoma at a South African tertiary hospital: A 21-year retrospective analysis by E Brits, E Gerber, I Iroka, L Mgidlana, J Willoughby, S Dhlamini, P Nxumalo, S Sefadi, A Mthembu, J B Sempa

“…To assess profiles, disease presentations, management and outcomes of patients with nephroblastoma at Universitas Academic Hospital Complex (UAHC), and to compare patients from SA and Lesotho, including differences between early and late presenters and reasons for delayed presentation. Methods. This retrospective cross-sectional study included 207 paediatric oncology patients treated for nephroblastoma at the Paediatric Haematology and Oncology Unit at UAHC, Bloemfontein, SA, from January 2000 to December 2020. …”
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Molecular-genetic mechanisms of the interaction between processes of cell response to mechanical stress and neuronal apoptosis in primary open-angle glaucoma by O. V. Saik, N. A. Konovalova, P. S. Demenkov, N. V. Ivanisenko, T. V. Ivanisenko, D. E. Ivanoshchuk, O. S. Konovalova, O. A. Podkolodnaya, I. N. Lavrik, N. A. Kolchanov, V. A. Ivanisenko

“…It was shown that genes associated with POAG are statistically significantly more often represented among the genes involved in the interactions between CRMS and neuronal apoptosis than it was expected by random reasons, which can be an explanation for the effect of POAG leading to the retinal ganglion cell death.…”
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Optimization of Urban Rail Transit Train Stock Utilization under Re-coupling Operation Mode by DENG Chengyuan, LU Jinsheng, ZHU Changfeng, SUN Yuanguang, MA Bin

“…［Result & Conclusion］ The optimized train stock utilization scheme of urban rail transit under the re-coupling operation mode can reasonably optimize the connection between different marshalling train trips and reduce the operation costs for enterprises.…”
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Exploring the metabolic patterns and response mechanisms of bile acids during fasting: A study with poultry as an example by Jun Zhang, Yujie Gong, Yidan Zhu, Qingduo Zeng, Hao Zhang, Ruili Han, Yujie Guo, Donghua Li, Yadong Tian, Xiangtao Kang, Yawei Yang, Zhuanjian Li, Ruirui Jiang

“…This study explored the metabolic patterns of bile acids during fasting and identified the main reasons for the accumulation of bile acids in the cecum, which provides a basis for fasting research and offers a reference for the formulation of fasting protocols.…”
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CMEs and SEPs During November–December 2020: A Challenge for Real‐Time Space Weather Forecasting by Erika Palmerio, Christina O. Lee, M. Leila Mays, Janet G. Luhmann, David Lario, Beatriz Sánchez‐Cano, Ian G. Richardson, Rami Vainio, Michael L. Stevens, Christina M. S. Cohen, Konrad Steinvall, Christian Möstl, Andreas J. Weiss, Teresa Nieves‐Chinchilla, Yan Li, Davin E. Larson, Daniel Heyner, Stuart D. Bale, Antoinette B. Galvin, Mats Holmström, Yuri V. Khotyaintsev, Milan Maksimovic, Igor G. Mitrofanov

“…We find that, despite some limitations arising from the models' architecture and assumptions, CMEs and shock‐accelerated SEPs can be reasonably studied and forecast in real time at least out to several tens of degrees away from the eruption site using the prediction tools employed here.…”
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Patient Perspectives on Evolving Diverticulitis Treatment: An Assessment of Patient Willingness to Enroll in a Randomized Controlled Trial by Annie Altman-Merino, MD, Kemberlee Bonnet, MA, David Schlundt, PhD, Jesse Wrenn, MD, PhD, Wesley H. Self, MD, MPH, Elisa J. Gordon, PhD, MPH, Alexander T. Hawkins, MD, MPH

“…Thirteen patients completed an interview. Reasons to participate included a desire to help others or contribute to scientific knowledge. …”
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Study of the Construction Sequence of Overlapping Tunnels by the Shield Tunneling Method: A Case Study of the Longest Overlapping Tunnel in China by Zhiyong Yang, Yaowen Ding, Yusheng Jiang, Kuanda Fang, Linwei Dong, Weiqiang Qi, Zheng Wei

“…In this study, the reasonable construction sequence of an overlapping tunnel shield is investigated. …”
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Vaccination against COVID-19 in patients with allergy: experience of the allergological center in Dnipro by Ye.M. Dytiatkovska, K.Yu. Gashynova, Ye.V. Korietskaia, M.A. Yevtushenko

“…As the COVID-19 vaccine will be administered to billions of individuals worldwide during the pandemic, there exists a reasonable fear of severe adverse reactions requiring constant vigilance and careful treatment, particularly in individuals with a history of severe allergy. …”
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Degradation kinetics, pathways, transformation products, and toxicity assessment of fluorochloridone in agricultural soils by Dong Zhao, Hongyu Chen, Shuo Shen, Enyu Lu, Junlong Feng, Hui Zhi, Lei Wang, Wei Li

“…These results are crucial for elucidating the environmental fate of FLC, assessing environmental risks, and guiding scientific and reasonable use. This research holds significant importance for the ecological environment protection in the Tibetan Plateau region.…”
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Epigenetic modulation of social cognition: exploring the impact of methylation in brain-derived neurotrophic factor and oxytocin receptor genes across sex by Hye Yoon Park, Suonaa Lee, Se Jun Koo, Zhenxu Li, Eunchong Seo, Eun Lee, Suk Kyoon An

“…Abstract Social cognition, which ranges from recognizing social cues to intricate inferential reasoning, is influenced by environmental factors and epigenetic mechanisms. …”
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Equity of intensive care unit bed resource allocation in ethnic minority areas of China—an empirical analysis based on geographical and population dimensions by Jing Kang, Rong Peng, Jun Feng, Xianjing Qin, Junxu Zhou, Meng Deng, Shanshan Meng, Decheng Lu

“…The ICU bed allocation by population dimensions was in a state of absolute equity, and the equity of geographic dimension was in a state of basic reasonableness. The contribution rate of intraregional differences is higher than that of inter-regional differences. …”
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Removal of Forearm Plate Leads to a Higher Risk of Refracture—A Systematic Review and Meta‐Analysis by Renwei Cao, Jianyu Zhang, Weitong Sun, Xieyuan Jiang, Kehan Hua, Dan Xiao, Chen Chen, Yejun Zha, Maoqi Gong

“…Results The total risk difference (RD) was 0.06 (0.04–0.09), indicating that the difference was significant. In the “Reasons for Removal” subgroup analysis, the RD of the “No Symptom” subgroup was 0.07 (95% CI = 0.04–0.11), while the RD of the “Symptoms” subgroup was 0.04 (95% CI = −0.02 to 0.10). …”
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Therapeutic Drug Monitoring of Vancomycin in Hemodialysis Patients in a Hospital in North-East Romania by Aurelia Crețu, Luanda Irina Mititiuc, Iulia-Daniela Lungu, Mihaela Mihaila, Irina Dima, Adrian Covic, Cristina Mihaela Ghiciuc

“…<b>Conclusions</b>: a therapeutic level of vancomycin can often be difficult to achieve because of different reasons, mainly in hemodialysis patients.…”
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Clinical features of the course of Hirschsprung’s disease in newborns and infants with consideration of the extent of colonic aganglionosis by V.P. Prytula, O.O. Kurtash, V.F. Rybalchenko, S.F. Hussaini

“…The severity of the course and late diagnosis are the main reasons for the appearance of severe complications of HD in newborns and infants - hypotrophy (67.70%), HD-associated enterocolitis (65.22%), toxic megacolon (3.31%) and anemia (49.89%). …”
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Middle hepatic vein incorporation in live donor liver graft transplantation; implication and safety by Mahmoud Ali Abdi, Tayeb Sabir Kareem, Assad Abidon Hassoun

“…In addition, early discharge of the donor is a reasonable option.            …”
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Fertility differences between two wild-type <i>Drosophila melanogaster</i> lines correlate with differences in the expression of the <i>Jheh</i> gene, which codes for an enzyme deg... by O. V. Andreenkova, N. V. Adonyeva, V. M. Efimov, N.  E. Gruntenko

“…The data obtained allow us to reasonably propose that the inter-line D. melanogaster polymorphism in the metabolism of the juvenile hormone is determined by its degradation (not by its synthesis) and correlates with the fertility level.…”
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Frequency anomalies and characteristics of extratropical cyclones during extremely wet, dry, windy, and calm seasons in the extratropics by H. Binder, H. Wernli

“…The results from the climate model and from ERA5 are mostly consistent, suggesting that the climate model captures the cyclone properties reasonably well. Compared to the climatology, extremely wet seasons are associated with positive anomalies in cyclone frequency in large parts of the extratropics. …”
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Practical Minimum Sample Size for Road Crash Time-Series Prediction Models by Fady M. A. Hassouna, Khaled Al-Sahili

“…Crash data in many countries are available only for the past 10 to 20 years, which makes it difficult to determine whether the data are sufficient to establish reasonable and accurate prediction rates. In this study, the effect of sample size (number of years used to develop a prediction model) on the crash prediction accuracy using Autoregressive integrated moving average (ARIMA) method was investigated using crash data for years 1971–2015. …”
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Optimizing education primary selection in universities: A fuzzy inference system with the mamdani method by Arif Sapta Mandala, Yuniar Ika Putri Pranyata

“…Mamdani provides recommendations based on prospective student data regarding cognitive abilities, language literacy, and mathematical reasoning. The results show that this system can guide prospective science and technology students in choosing majors that suit their interests and potential. …”
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Understanding parental choices related to infant sleep practices in the United States using a mixed methods approach by Hannah Sahud, Rachel P. Berger, Megan Hamm, Emily Heineman, Flor Cameron, Julia Wasilewski, Ashley Griffin, Gysella B. Muniz

“…Conclusions Our data are consistent with previous studies which demonstrate that lack of access to a recommended sleep space or lack of knowledge about AAP sleep guidelines are not the primary reasons for practicing non-recommended sleep habits. …”
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