A repurposing strategy for Hsp90 inhibitors demonstrates their potency against filarial nematodes. by Victoria Gillan, Kerry O'Neill, Kirsty Maitland, Francis M Sverdrup, Eileen Devaney

“…The results from all three assays correlated reasonably well and one particular compound, NVP-AUY922, was shown to be particularly active, inhibiting Mf output from female worms at concentrations as low as 5.0 nanomolar after 6 days exposure to drug. …”
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Design of OFDM-IM system based on IRS-assisted by Mengmeng ZHAO, Liming HE, Fangfang LIU

“…Index modulation (IM) and intelligent reflecting surface (IRS) are emerging mobile communication technologies.In order to improve the reliability of traditional orthogonal frequency division multiplexing (OFDM) system, an orthogonal frequency division multiplexing with index modulation (OFDM-IM) system based on IRS-assisted was designed.Firstly, the OFDM-IM system was designed by using spatial modulation and frequency domain modulation to increase the Euclidean distance between subcarriers.Then, by establishing an equivalent circuit model, a practical IRS model was obtained.Finally, an alternating optimization algorithm was used to optimize the active transmission power of the access point (AP) and passive beamforming of the IRS jointly.The simulation results show that compared to the benchmark scheme, the symbol error rate (SER) or bit error rate (BER) of the OFDM-IM system based on IRS-assisted can be reduced by 60%～90%.Especially in the case of high signal-to-noise ratio, the SER or BER of the system can reach 1.0×10^-6, which indicates that the introduction of IM and IRS technologies has optimized the link transmission quality of end-to-end communication system.In addition, based on the IRS-assisted OFDM-IM system as the standard, simulations are conducted to demonstrate the impact of various parameters from the IRS model and IM.It concludes that the parameters in the system should be selected reasonably according to channel state information (CSI).…”
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A Hybrid Deep Learning Framework for Network Flow Forecasting of Power Grid Enterprise by Xin Huang, Ting Hu, Pei Pei, Qin Li, Xin Zhang

“…To prevent network congestion, this article proposes a novel network flow forecasting model, which is composed of variational mode decomposition (VMD), GRU-xgboost block, and a forecasting adjustment block, to grasp the changing patterns and trends of network flow in advance, and to formulate reasonable and effective flow management strategies and meet the requirements of users for network service quality. …”
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Seismic Behavior Analysis of Damaged Steel Fiber-Reinforced High-Strength Concrete Frame Joints Strengthened by FRP by Wang Tingyan, Zhou Yun, Zhang Junwei

“…Therefore, the constitutive model, element, end constraint, and loading method used in the finite element numerical simulation of this paper were reasonable, which can provide reference for the similar research in the future.…”
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The Exile Experience Reconsidered: a Comparative Perspective in European Cultural Migration during the Interwar Period by Renato Camurri

“…This paper deals with exile in the 20th century and makes some suggestions for a reconsideration of this experience. The reasons for its peculiarity lie in a series of political, religious, racial and moral elements but when we speak of exile we are implicitly referring to substantially different experiences and phenomena: social exile, political exile and intellectual exile.The historiography of cultural migration has been through new and important developments over the past twenty years, developments that have enlarged the field across the borders of where sector-based studies grew. …”
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Experiment and Dynamic Characteristic Analysis of Double Pitch Time Sharing Meshing Silent Chain by Ding Song, Yang Shuchen, Zhang Xiaoqi, Gu Dongwei, Shao Guiyang, Jiang Donglin

“…The experimental results prove that the rationality of double pitch time share meshing silent chain design is reasonable.…”
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The EU Soft Power in the Global Equilibrium by A. Baykov

“…The multi-faceted relations between Russia and the European Union with closely interwoven national interests of different countries do not make these relationships easier whereas a whole array of historical and psychological problems do not add trust. Therefore, it is reasonable to opt for formalized dialogue institutions. …”
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Parameter Sensitivity and Inversion Analysis for a Concrete Face Rockfill Dam Based on CS-BPNN by Yue Chen, Chongshi Gu, Chenfei Shao, Xiangnan Qin

“…The numerical results demonstrate that the parameters obtained with the proposed method are reasonable and its feasibility is validated.…”
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Hot Topic Propagation Model and Opinion Leader Identifying Model in Microblog Network by Yan Lin, Huaxian Li, Xueqiao Liu, Suohai Fan

“…The experiments in the data, collected from the Sina Micro-blog from October 2012 to November 2012 and from January 2013 to February 2013, show that our models predict the trend of hot topic efficiently and the opinion leaders we found are reasonable.…”
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Capgras syndrome, an interesting but rare phenomenon in Psychiatry: A case series by Arghya Halder, Sagarika Ray, Manish Kumar, Amit Kumar Bhattacharya

“…Thus, olanzapine could be a reasonable choice in treating Capgras syndrome in patient populations where there are no contraindications to prescribe this drug.…”
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Systematic Performance Evaluation of Shield TBM Cutters for Excavating Multiple Soft Rock by Chuyuan Cao, Kui Zhang

“…The evaluation results show that the method has an intrinsic applicability in helping to make a reasonable trade-off between cost and cutting performance during the cutter selection process.…”
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Ethical aspects of the use of social networks during the employment process by Branislav Sančanin

“…Employers cite inappropriate photos, videos or information, followed by announcements pertaining to alcohol or drug consumption, as well as detected discriminatory comments, as the most common reasons for not hiring candidates after verification through social networks.…”
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Enhancing fingerprint identification using Fuzzy-ANN minutiae matching by S.P. Singh, Dinesh Kumar Nishad, Saifullah Khalid

“…‘Based on Minutiae and Neural Networks,’ this paper introduces a robust fingerprint identification system that significantly enhances the accuracy of matching fingerprints, especially those altered due to various reasons such as scars or mutilations. Utilizing a combination of minutiae-based matching and neural network algorithms, the system is designed to overcome the limitations of traditional methods, which often fail under less-than-ideal conditions. …”
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Research on key "acupoint" mining technology for special information system by ZOU Zilong, WANG Junlin, AN Shujie, LYU Changyuan, YU Minggang, NIU Yanjie

“…Finally, taking the special information system under the background of urban unmanned attack operation as an example, the scientific and reasonable of the proposed method is verified.…”
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Pedagogy in the Era of the Post-Non-Classical Science by V. L. Benin

“…The author analyses numerous publications concerning the above problem and presents his opinion on the actual reasons for stagnation in the modern national pedagogy. …”
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Separate Collection of Packaging Wastes within the Scope of Integrated Solid Waste Management: The case study of Yakutiye District in Erzurum City by Zeynep Eren, Emre Erdoğan

“…Besides, the landfill areas are considered as one of the reasons of global warming due to its greenhouse gas emission. …”
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RECONCILIATION AS A MISSIONAL PARADIGM FOR POST-1994 SOUTH AFRICA

“…There is a need to spell out the reasons for reconciliation as a paradigm for missiology in South Africa. …”
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Using Situational Judgement Test to Assess The ‘Pancasila’ Student Profiles Construct: A Systematic Literature Review by Tri Wahyuni, Wardani Rahayu, Dali Santun Naga

“…Merdeka Curriculum contains the ‘Pancasila’ Student Profiles, those are  global diversity, cooperation, critical reasoning, creativity and independence.   This systematic literature review answers three basic questions, namely (1) in what fields is SJT used and for what purposes? …”
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Improved Genetic Algorithm to Solve the Scheduling Problem of College English Courses by Jing Xu

“…Firstly, a variable-length decimal coding scheme satisfying the same course that can be scheduled at different times, different classrooms, and different teaching weeks per week is proposed, which fully considers the flexibility of classrooms and time arrangements of the course and makes the scheduling problem more reasonable. Secondly, a problem-specific local search operator is designed to accelerate the convergence speed of the algorithm. …”
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A latent profile analysis of the functions of binge eating by Elyse O’Loghlen, Roslyn Galligan, Sharon Grant

“…Discussion The identification of these distinct profiles suggests that individuals present with differentiated, inter-related patterns or reasons for BE. These clinically relevant profiles may inform binge-eating intervention choice and the targeting of specific maintenance factors within profiles. …”
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