Type 2 Diabetes Mellitus Epidemiology of and its Complications by Julio Armando Sánchez Delgado, Nailé Edita Sánchez Lara

“…Ischemic heart disease (39.5 % X2=7.1 RAP=23.4 %), arterial hypertension (23.4 % X2=45.6) and bronchial asthma (16 % X2=74.6) were the associated diseases of higher incidence. …”
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Tests of a New Solar Flare Model Against D and E Region Ionosphere Data by David E. Siskind, McArthur Jones Jr., Jeffrey W. Reep, Doug P. Drob, Srimoyee Samaddar, Scott M. Bailey, Shun‐Rong Zhang

“…This agrees with previously published observations and model estimates, all of which suggest greater HF absorption than the operational D region absorption prediction model (swpc.noaa.gov/products/d‐region‐absorption‐predictions‐d‐rap). Finally, our theoretical comparison with previously published empirical models derived from very low frequency data was less clear due, in part, to large differences between the different empirical models.…”
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Causal association between circulating α-Klotho levels and venous thromboembolism: a two-sample Mendelian randomization study by Yanmin Song, Liping Cao, Hui Long

“…The fixed inverse variance weighted (IVW), MR-Egger, MR-Robust Adjusted Profile Score (RAPS) and the weighted-median methods were utilized to investigate the causal associations of circulating α-Klotho levels with different types of VTE. …”
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Do You Speak Dialect? Yes! by Vytautas Kardelis, Gabriela Forgeron

“…The calculation of the dialect index according to the formula developed in this study demonstrated that, with one exception, RAP informants are more ‘dialectal’ than RAU informants with respect to objective dialect. …”
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肾透明细胞癌差异表达基因的筛选及其核心基因相应miRNA和lncRNA 预测分析 by 朱合欢, 赵虎, 林智文, 王洁, 路君, 谭建明

“…【结果】共筛选出427个差异表达基因，这些差异表达基因在GO功能分析上主要与催化活性、受体活性和细胞黏附分子活性等功能相关，KEGG 信号通路富集结果则表明其主要与PPAR、Rap1 以及细胞因子受体相互作用等信号通路相关。从这些差异表达基因中筛选出11个核心基因，并预测到134个相应miRNA，接着对5个与ccRCC总体生存率相关的miRNA在STARBASE中共预测到6个相应lncRNA。…”
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A Network Pharmacology-Based Approach for Exploring Key Active Compounds and Pharmacological Mechanisms of Tangshen Formula for Treatment of Diabetic Nephropathy by Weie Zhou, Xuefeng Zhou, Yuan Zhang, Yuyang Wang, Wenjie Wu, Haojun Zhang, Tingting Zhao, Liang Peng, Hailing Zhao, Ping Li

“…The quercetin, naringenin, kaempferol, and isorhamnetin as key active compounds and the PI3K-Akt signaling pathway, TNF signaling pathway, nonalcoholic fatty liver disease (NAFLD), focal adhesion, rap1 signaling pathway, T cell receptor signaling pathway, MAPK signaling pathway, and insulin resistance as the key molecular mechanisms play important roles in TSF treating DN. …”
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Insights from Dysregulated mRNA Expression Profile of β-Cells in Response to Proinflammatory Cytokines by Zhen Wang, Kunlin Huang, Jing Xu, Jia Liu, Ying Zheng

“…KEGG analysis showed that these differentially expressed genes were involved with “antigen processing and presentation,” “TNF signaling pathway” and “type 1 diabetes,” “cell cycle,” “necroptosis,” and “Rap1 signaling pathway.” We also constructed the networks of differentially expressed circRNAs and mRNAs. …”
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Antimicrobial susceptibilities of oral Neisseria from men on HIV pre-exposure prophylaxis in Hanoi, Vietnam by Huan Vinh Dong, Paul Adamson, Dieu Hoa Pham, Quynh Hoa Pham, Hai Ha Long Le, Loc Quang Pham, Hao Thi Minh Bui, Giang Minh Le, Jeffrey D. Klausner

“…Oxidase-positive Gram-negative diplococci were identified using the Remel RapID NH system. Minimum inhibitory concentrations (MICs) to azithromycin, ceftriaxone, cefixime, and doxycycline were determined using Etests. …”
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Clinical Features of Combined Central Retinal Artery and Vein Occlusion by Hao Wang, Yongye Chang, Fen Zhang, Rong Yang, Suxia Yan, Jieying Dong, Minglian Zhang, Shaomin Peng

“…FFA showed prolonged arm-to-retina time (ART) and retinal arteriovenous passage time (RAP) (17.1 ± 4.9 s and 12.1 ± 8.8 s, respectively). …”
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LIN28A-dependent lncRNA NEAT1 aggravates sepsis-induced acute respiratory distress syndrome through destabilizing ACE2 mRNA by RNA methylation by Jun Liu, Xiang Li, Peng Yang, Yufeng He, Weilong Hong, Yawei Feng, Zhiqiang Ye

“…Methods Here RNA methylation was detected by methylated RNA immunoprecipitation (MeRIP), RNA stability was determined by RNA decay assay while RNA antisense purification (RAP) was used to identify RNA-protein interaction. …”
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Tregs levels and phenotype modifications during Amyotrophic Lateral Sclerosis course by Elisabetta Zucchi, Elisabetta Zucchi, Federico Banchelli, Cecilia Simonini, Sara De Biasi, Ilaria Martinelli, Giulia Gianferrari, Giulia Gianferrari, Domenico Lo Tartaro, Andrea Cossarizza, Andrea Cossarizza, Roberto D’Amico, Roberto D’Amico, Jessica Mandrioli, Jessica Mandrioli

“…Additionally, we explored whether measures of ALS progression, such as the decline over time in the revised ALS Functional Rating Scale (ALSFRS-r) or forced vital capacity (FVC) correlated Treg levels and whether Treg phenotype varied during the course of ALS.MethodsTotal Tregs (detected by CD3, CD4, FoxP3, CD25, and CD127) were quantified at five time points over 54 weeks in 21 patients in the placebo arm of the RAP-ALS trial; next they were characterized for the expression of surface markers including CD38, CD39, CXCR3, and PD1. …”
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Nghiên cứu phân lập vi khuẩn nội sinh từ một số giống lan rừng by Huu Tho Nguyen, Thị Bích Phượng Trương, Thị Xuân Tuý Hồ, Thành Phạm, Thị Kim Cúc Nguyễn

“…Hình thái khuẩn lạc của các chủng được phân lập chủ yếu có màu trắng (73,4%), trơn nhầy (60%), mép tròn đều (63,3%), một số ít có bề mặt khô ráp hoặc bóng nhẵn, viền mép dạng gợn sóng. Kết quả nghiên cứu đặc điểm hóa sinh cho thấy 18/30 chủng có khả năng phân giải lân; 15/30 chủng có khả năng sinh IAA; 16/30 chủng có khả năng cố định đạm; và 18/30 chủng có khả năng sinh NH3. …”
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Impact of host climate model on contrail cirrus effective radiative forcing estimates by W. Zhang, K. Van Weverberg, K. Van Weverberg, K. Van Weverberg, C. J. Morcrette, C. J. Morcrette, W. Feng, W. Feng, K. Furtado, K. Furtado, P. R. Field, P. R. Field, C.-C. Chen, A. Gettelman, P. M. Forster, D. R. Marsh, A. Rap

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Should the Food and Drug Administration Limit Placebo-Controlled Trials? by Max Goodman, Connor Pedersen

“…Regulatory Affairs Professionals Society (RAPS). http://www.raps.org/news-and-articles/news-articles/2019/8/fda-finalizes-guidance-on-placebos-and-blinding-fo. …”
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