La Responsabilidad Ampliada del Productor como instrumento para lograr una efectiva economía circular. Aproximación a la legislación de la UE y la ley residuos y suelos contaminado... by Aitana de la Varga Pastor

“…Este trabajo analiza de forma crítica la Responsabilidad Ampliada del Productor (RAP) como instrumento para lograr una efectiva economía circular. …”
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"Antes que a Bala Perdida me Ache": Saúde Mental da População Negra e Violência Policial by Geovana Afonso do Nascimento, Ana Paula Medeiros

“…A arte, sobretudo as letras de rap, auxiliaram nesse processo de apreensão do fenômeno. …”
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TMAO-Activated Hepatocyte-Derived Exosomes Are Widely Distributed in Mice with Different Patterns and Promote Vascular Inflammation by Xiang Liu, Jiazichao Tu, Ziqin Zhou, Bingxin Huang, Jianrong Zhou, Jimei Chen

“…Results. Phgdh, Mdh2, Echs1, Rap2a, Gpd1l, and Slc3a2 were identified as hub genes that may be involved in the production of TMAO-Exos. …”
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Comparison of optical coherence tomography vs. fluorescein angiography-based macular neovascularization classifications in age-related macular degeneration by Gábor G. Deák, Klaudia Birner, Bianca S. Gerendas, Georgios Mylonas, Günther Weigert, Martin Michl, Irene Steiner, Ursula M. Schmidt-Erfurth

“…Kappa coefficients for agreement between FA and OCT MNV types were 0.58 [0.52; 0.64] (type 1/occult), 0.46 [0.38; 0.55] (type 2/classic), and 0.53 [0.44; 0.62] (type 3/RAP). Significant differences in the volumes of intraretinal fluid (IRF), subretinal fluid (SRF), and pigment epithelial detachment (PED) were noted among MNV types (p < 0.0001). …”
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Perfluorooctane sulfonate (PFOS) induced bone loss by inhibiting FoxO1-mediated defense against oxidative stress in osteoblast by Liming Xue, Jiale Xu, Ping Xiao, Yiping Jiang, Yuanjie Lin, Chao Feng, Yu’e Jin, Zhijun Zhou, Guoquan Wang, Dasheng Lu

“…The DEGs in PFOS-treated groups were involved in multiple pathways, including FoxO, HIF-1, Rap1, Hippo, and sphingolipid signaling. FoxO1 was validated as the key gene which regulates osteogenic differentiation and redox status. …”
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Bioinformatics Analysis for Identifying Differentially Expressed MicroRNAs Derived from Plasma Exosomes Associated with Radiotherapy Resistance in Non-Small-Cell Lung Cancer by Lirong Zeng, Guilin Zeng, Zhong Ye

“…Further, 2 other target genes were involved in the Rap1 signaling pathway (the upstream pathway of PI3K-Akt). …”
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Type 2 Diabetes Mellitus Epidemiology of and its Complications by Julio Armando Sánchez Delgado, Nailé Edita Sánchez Lara

“…Ischemic heart disease (39.5 % X2=7.1 RAP=23.4 %), arterial hypertension (23.4 % X2=45.6) and bronchial asthma (16 % X2=74.6) were the associated diseases of higher incidence. …”
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Development of Cross-Sector Collaboration Indicators for Accelerating the Reduction of Stunting in South Sulawesi, Indonesia by Balqis Balqis, Suci Rahmadani, Muh. Yusri Abadi, St. Rosmanely, Arif Anwar, Laksmi Trisasmita, Ni Made Viantika Sulianderi, Faizal Fahmi, Arsunan Arsin, Muh. Amri Arfandi, Nur Annisa Hamka, Amaliah Amriani. AS

“…Method: This qualitative study utilized a rapid assessment procedure (RAP) to generate cross-sector collaboration indicators through in-depth interviews with five key informants and four experts. …”
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Causal association between circulating α-Klotho levels and venous thromboembolism: a two-sample Mendelian randomization study by Yanmin Song, Liping Cao, Hui Long

“…The fixed inverse variance weighted (IVW), MR-Egger, MR-Robust Adjusted Profile Score (RAPS) and the weighted-median methods were utilized to investigate the causal associations of circulating α-Klotho levels with different types of VTE. …”
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Do You Speak Dialect? Yes! by Vytautas Kardelis, Gabriela Forgeron

“…The calculation of the dialect index according to the formula developed in this study demonstrated that, with one exception, RAP informants are more ‘dialectal’ than RAU informants with respect to objective dialect. …”
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A Network Pharmacology-Based Approach for Exploring Key Active Compounds and Pharmacological Mechanisms of Tangshen Formula for Treatment of Diabetic Nephropathy by Weie Zhou, Xuefeng Zhou, Yuan Zhang, Yuyang Wang, Wenjie Wu, Haojun Zhang, Tingting Zhao, Liang Peng, Hailing Zhao, Ping Li

“…The quercetin, naringenin, kaempferol, and isorhamnetin as key active compounds and the PI3K-Akt signaling pathway, TNF signaling pathway, nonalcoholic fatty liver disease (NAFLD), focal adhesion, rap1 signaling pathway, T cell receptor signaling pathway, MAPK signaling pathway, and insulin resistance as the key molecular mechanisms play important roles in TSF treating DN. …”
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Insights from Dysregulated mRNA Expression Profile of β-Cells in Response to Proinflammatory Cytokines by Zhen Wang, Kunlin Huang, Jing Xu, Jia Liu, Ying Zheng

“…KEGG analysis showed that these differentially expressed genes were involved with “antigen processing and presentation,” “TNF signaling pathway” and “type 1 diabetes,” “cell cycle,” “necroptosis,” and “Rap1 signaling pathway.” We also constructed the networks of differentially expressed circRNAs and mRNAs. …”
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Antimicrobial susceptibilities of oral Neisseria from men on HIV pre-exposure prophylaxis in Hanoi, Vietnam by Huan Vinh Dong, Paul Adamson, Dieu Hoa Pham, Quynh Hoa Pham, Hai Ha Long Le, Loc Quang Pham, Hao Thi Minh Bui, Giang Minh Le, Jeffrey D. Klausner

“…Oxidase-positive Gram-negative diplococci were identified using the Remel RapID NH system. Minimum inhibitory concentrations (MICs) to azithromycin, ceftriaxone, cefixime, and doxycycline were determined using Etests. …”
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Clinical Features of Combined Central Retinal Artery and Vein Occlusion by Hao Wang, Yongye Chang, Fen Zhang, Rong Yang, Suxia Yan, Jieying Dong, Minglian Zhang, Shaomin Peng

“…FFA showed prolonged arm-to-retina time (ART) and retinal arteriovenous passage time (RAP) (17.1 ± 4.9 s and 12.1 ± 8.8 s, respectively). …”
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Nghiên cứu phân lập vi khuẩn nội sinh từ một số giống lan rừng by Huu Tho Nguyen, Thị Bích Phượng Trương, Thị Xuân Tuý Hồ, Thành Phạm, Thị Kim Cúc Nguyễn

“…Hình thái khuẩn lạc của các chủng được phân lập chủ yếu có màu trắng (73,4%), trơn nhầy (60%), mép tròn đều (63,3%), một số ít có bề mặt khô ráp hoặc bóng nhẵn, viền mép dạng gợn sóng. Kết quả nghiên cứu đặc điểm hóa sinh cho thấy 18/30 chủng có khả năng phân giải lân; 15/30 chủng có khả năng sinh IAA; 16/30 chủng có khả năng cố định đạm; và 18/30 chủng có khả năng sinh NH3. …”
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Should the Food and Drug Administration Limit Placebo-Controlled Trials? by Max Goodman, Connor Pedersen

“…Regulatory Affairs Professionals Society (RAPS). http://www.raps.org/news-and-articles/news-articles/2019/8/fda-finalizes-guidance-on-placebos-and-blinding-fo. …”
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