Pancreatic Cancer: Molecular, Biochemical, Chemopreventive, and Therapeutic Aspects by Juan Iovanna, José Luis Neira

“…These approaches are likely to comprise a mixture of targeted agents in combination with conventional chemotherapy and radiotherapy. For a clinically significant effect to be achieved, treatment strategies should either be in the form of (1) a horizontal approach, in which several oncogenic pathways (as those described in this series of reviews) are inhibited; or (2) a vertical approach, whereby multiple levels of a major pathway are targeted. …”
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Metastatic Breast Cancer to the Gastrointestinal Tract: Report of Five Cases and Review of the Literature by Massimo Ambroggi, Elisa Maria Stroppa, Patrizia Mordenti, Claudia Biasini, Adriano Zangrandi, Emanuele Michieletti, Elena Belloni, Luigi Cavanna

“…The majority of the patients underwent chemotherapy and endocrine therapy, someone surgery and radiotherapy. GI metastases from breast cancer are rare, but possible, and a very late recurrence can also occur. …”
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Salivary IL-17A, IL-17F, and TNF-α Are Associated with Disease Advancement in Patients with Oral and Oropharyngeal Cancer by Kinga Zielińska, Bożenna Karczmarek-Borowska, Konrad Kwaśniak, Justyna Czarnik-Kwaśniak, Aleksandra Ludwin, Bogumił Lewandowski, Jacek Tabarkiewicz

“…Despite progress in systemic therapy and radiotherapy, there has only been a slight improvement in the five-year survival rate. …”
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Psoralidin: emerging biological activities of therapeutic benefits and its potential utility in cervical cancer by Tanya Tripathi, Apoorva Chaudhary, Divya Janjua, Udit Joshi, Nikita Aggarwal, Chetkar Chandra Keshavam, Alok Chandra Bharti

“…This unique characteristic suggests its potential to be used as an adjunct molecule in combination with existing treatment to enhance the efficacy of chemo/radiotherapy for treating CaCx. However, low bioavailability and intestinal efflux limit the use of psoralidin in clinical applications. …”
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Real-World Treatment Patterns in Men with Castration- Resistant Prostate Cancer Receiving Docetaxel by Keith L. Davis, Benjamin Gutierrez, Teresa Zyczynski, James A. Kaye

“…Other non-chemotherapy treatments used with docetaxel were hormonal therapy (22.8%), radiotherapy (17.3%), and surgery (4.1%). Most patients (75%) received ≥4 docetaxel cycles, half received ≥6 cycles, 25% received ≥8 cycles and 10% received ≥10 cycles. …”
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Sex and authorship in global cancer research by Deborah Mukherji, Ophira Ginsburg, Grant Lewison, Richard Sullivan, Verna Vanderpuye, Winnie K W So, Miriam Mutebi, Nazik Hammad, Julie Torode, Erica Liebermann

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Pelvic Radiation Disease Management by Hyperbaric Oxygen Therapy: Prospective Study of 44 Patients by Mehdi Ouaïssi, Stephanie Tran, Diane Mege, Vivien Latrasse, Alain Barthelemy, Nicolas Pirro, Philippe Grandval, James Lassey, Igor Sielezneff, Bernard Sastre, Mathieu Coulange

“…The median of delay between radiotherapy and HBOT was 26 months (3–175). We evaluated the results of HBOT, using SOMA-LENT Scale. …”
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Platelet membrane biomimetic nanomedicine induces dual glutathione consumption for enhancing cancer radioimmunotherapy by Xiaopeng Li, Yang Zhong, Pengyuan Qi, Daoming Zhu, Chenglong Sun, Nan Wei, Yang Zhang, Zhanggui Wang

“…Radiotherapy (RT) is one of the most common treatments for cancer. …”
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Advances in Therapy for Urothelial and Non-Urothelial Subtype Histologies of Advanced Bladder Cancer: From Etiology to Current Development by Whi-An Kwon, Ho Kyung Seo, Geehyun Song, Min-Kyung Lee, Weon Seo Park

“…For localized disease, curative options such as surgical resection or radiotherapy are available; however, treatment options become more limited in recurrence or metastasis, where systemic therapy is primarily used to control disease progression and palliate symptoms. …”
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Artificial intelligence-derived gut microbiome as a predictive biomarker for therapeutic response to immunotherapy in lung cancer: protocol for a multicentre, prospective, observat... by Ryo Toyozawa, Fumihiro Shoji, Takanori Yamashita, Fumihiko Kinoshita, Shinkichi Takamori, Takatoshi Fujishita, Kensaku Ito, Koji Yamazaki, Naoki Nakashima, Tatsuro Okamoto

“…Introduction Immunotherapy is the fourth leading therapy for lung cancer following surgery, chemotherapy and radiotherapy. Recently, several studies have reported about the potential association between the gut microbiome and therapeutic response to immunotherapy. …”
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Immunotherapy in Recurrent Ovarian Cancer by Keyao Chen, Jingjing Wang, Meng Yang, Shaoqiong Deng, Li Sun

“…Methods: We systematically reviewed recent immunotherapy advances for recurrent ovarian cancer, including the efficacy and mechanisms of single and dual immune checkpoint inhibitors, checkpoint inhibitor combinations with chemotherapy or radiotherapy, anti-angiogenic agents, PARP inhibitors, antibody–drug conjugates (ADC), tumor vaccines, and adoptive cell therapies (ACT). …”
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Targeting lipid metabolism: novel insights and therapeutic advances in pancreatic cancer treatment by Yanyan Zhang, Zhichao Yang, Yuchen Liu, Jinjin Pei, Ruojie Li, Yanhui Yang

“…Standard treatments for PC such as surgical resection, chemotherapy, and radiotherapy. However, these therapies often face significant challenges, including biochemical recurrence and drug resistance. …”
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Radioprotective Effects of Vitis vinifera L. Seed against Radiation-Induced Short-Term Memory Loss in Young Adult Wistar Rats by Ayomide Abe, Fatai Balogun, Olugbenga Ayannuga

“…While dose fractionation, intensity-modulated radiotherapy, and neural stem cell transplantation have demonstrated limited effectiveness, natural plant antioxidants offer a promising alternative. …”
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External validation of radiobiological models for local control prediction in lung cancer patients treated with stereotactic body radiation therapy by Bao-Tian Huang, Pei-Xian Lin, Ying Wang, Li-Mei Luo

“…The performance of the prediction models was assessed through the AUC values of the receiver operating characteristic (ROC) curve and the calibration plots.ResultsLocal recurrence was observed in 38.6% of patients (59/153) within two years, and in 43.1% (66/153) within three years after the radiotherapy. The ROC curves indicated discriminative power for all the 2-year and 3-year models, with the exception of the Klement model. …”
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Autologous Fat Grafting Reduces Pain in Irradiated Breast: A Review of Our Experience by Fabio Caviggioli, Luca Maione, Francesco Klinger, Andrea Lisa, Marco Klinger

“…Both procedures were followed by radiotherapy. We performed fat grafting following Coleman’s procedure. …”
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Swallowing-related muscle inflammation and fibrosis induced by a single dose of radiation exposure in mice by Shuntaro Soejima, Chia-Hsien Wu, Haruna Matsuse, Mariko Terakado, Shinji Okano, Tsuyoshi Inoue, Yoshihiko Kumai

“…Abstract Background Although radiotherapy is commonly used to treat head and neck cancer, it may lead to radiation-associated dysphagia (RAD). …”
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aPD-L1-facilitated theranostic and tumor microenvironment remodeling of pancreatic cancer via docetaxel-loaded phase-transformation nanoparticles triggered by low-intensity pulsed... by Yi Tang, Qingling Shen, Peng Lin, Zhixin Chen, Denghui Fan, Minling Zhuo, Yajiao Gan, Yixi Su, Qingfu Qian, Liwu Lin, Ensheng Xue, Zhikui Chen

“…Additionally, hypoxia and immune suppression within the tumor contribute to poor responses to radiotherapy and chemotherapy, ultimately leading to an unfavorable prognosis. …”
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Prediction of Multiple Organ Failure Complicated by Moderately Severe or Severe Acute Pancreatitis Based on Machine Learning: A Multicenter Cohort Study by Fumin Xu, Xiao Chen, Chenwenya Li, Jing Liu, Qiu Qiu, Mi He, Jingjing Xiao, Zhihui Liu, Bingjun Ji, Dongfeng Chen, Kaijun Liu

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A Canadian Perspective on Systemic Therapy for Recurrent or Metastatic Nasopharyngeal Carcinoma by Anna Spreafico, Eric Winquist, Cheryl Ho, Brian O’Sullivan, Nathaniel Bouganim, Neil Chua, Sarah Doucette, Lillian L. Siu, Desiree Hao

“…Although the majority of patients with nasopharyngeal carcinoma (NPC) present with early-stage or locoregional disease that can be treated with definitive radiotherapy, approximately 20% of patients experience disease recurrence, and 15% present with metastatic disease that is not amenable to curative therapy. …”
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Metastatic Basal Cell Carcinoma: A Biological Continuum of Basal Cell Carcinoma? by Karaninder S. Mehta, Vikram K. Mahajan, Pushpinder S. Chauhan, Anju Lath Sharma, Vikas Sharma, C. Abhinav, Gayatri Khatri, Neel Prabha, Saurabh Sharma, Muninder Negi

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