Nanoparticles Modulating the Immune Microenvironment in Breast Cancer Treatment by Guo LJ, Wu J, Lu W, Li J, Wang Y, Yang H, Wang TZ

“…Li-Juan Guo,1 Jinsheng Wu,1 Weifeng Lu,2 Jing Li,1 Yeling Wang,1 Hui Yang,1 Tian-Zhu Wang3 1Department of Radiotherapy, The First Affiliated Hospital of Hainan Medical University, Haikou, 570102, People’s Republic of China; 2Institute of Oncology, The First Affiliated Hospital of Hainan Medical College Institute of Oncology, Haikou, 570102, People’s Republic of China; 3Department of Radiation Oncology, Hainan Cancer Hospital, Haikou, 570311, People’s Republic of ChinaCorrespondence: Tian-Zhu Wang, Department of Radiation Oncology, Hainan Cancer Hospital, Haikou, 570311, People’s Republic of China, Email pillarsky@126.comAbstract: Breast cancer remains a significant therapeutic challenge, with the immune microenvironment playing a crucial role in its progression and treatment response. …”
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Molecular Detection of Minimal Residual Cancer in Surgical Margins of Head and Neck Cancer Patients by A. Peggy Graveland, Michiel de Maaker, Boudewijn J. M. Braakhuis, Remco de Bree, Simone E. J. Eerenstein, Elisabeth Bloemena, C. René Leemans, Ruud H. Brakenhoff

“…Distinguishing MRC from preneoplasic lesions is important to tailor postoperative radiotherapy more adequately. Here we investigated the suitability of quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR) using human Ly-6D (hLy-6D) transcripts as molecular marker to detect MRC in surgical margins.…”
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Treatment of the Induration of the Soft Tissue of the Lower Eyelids After Accidental Oil Injections by Vladimir Safronov, MD, PhD

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Brentuximab Vedotin Treatment for Primary Refractory Hodgkin Lymphoma by Hung-Bo Wu, Shyh-An Yeh, Huei-Yung Chen

“…The tumor responded to induction chemotherapy transiently, but local progression was noted during subsequent cycles of treatment. Salvage radiotherapy to the mediastinal tumor, obtained no remission but was followed by rapid in-field progression and then lung metastasis. …”
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Respiratory Failure Associated with Ascariasis in a Patient with Immunodeficiency by Lanocha Aleksandra, Zdziarska Barbara, Lanocha-Arendarczyk Natalia, Kosik-Bogacka Danuta, Guzicka-Kazimierczak Renata, Marzec-Lewenstein Ewa

“…In industrialized countries, risk groups for parasitic diseases include travelers, recent immigrants, and patients with immunodeficiency following chemotherapy and radiotherapy and AIDS. A 66-year-old Polish male was admitted in December 2012 to the Department of Haematology in a fairly good general condition. …”
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Metastatic Lesion of the Tibia from Renal Cell Carcinoma by Piotr Młodożeniec, Krzysztof Balawender, Mateusz Zasadny

“…The tibial lesion was treated with local radiotherapy, and because of the progression of the tibia lesion, a decision was made to amputate the leg. …”
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Non-professional phagocytosis of senescent cancer cells revealed in a 3D-bioprinted model of an irradiated lung tumour by Parul Yadav, Pritiranjan Mondal, Sibani Jani, Deepak K. Saini, Kaushik Chatterjee

“…This study explores the application of extrusion-based 3D bioprinting technology to create complex scaffolds mimicking the microenvironment of senescent cancer cells induced by radiotherapy. Using a viscoelastic hydrogel bioink composed of a blend of alginate and gelatin, we fabricated scaffolds with porosity and mechanical properties appropriate for culturing lung cells. …”
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An aggregation-induced emission-active lysosome hijacker: Sabotaging lysosomes to boost photodynamic therapy efficacy and conquer tumor therapeutic resistance by Hang Zou, Pingping Wang, Zhihao Bai, Liping Liu, Jingtong Wang, Yanfang Cheng, Bairong He, Zujin Zhao, Lei Zheng

“…This ultimately causes severe cell damage and restores the sensitivity of tumor cells to radiotherapy and chemotherapy. Thus, QM-DMAC serves as a highly efficient lysosome-targeting photosensitizer and an excellent therapeutic sensitizer. …”
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PPARα-mediated lipid metabolism reprogramming supports anti-EGFR therapy resistance in head and neck squamous cell carcinoma by Valentin Van den bossche, Julie Vignau, Engy Vigneron, Isabella Rizzi, Hannah Zaryouh, An Wouters, Jérôme Ambroise, Steven Van Laere, Simon Beyaert, Raphaël Helaers, Cédric van Marcke, Lionel Mignion, Elise Y. Lepicard, Bénédicte F. Jordan, Céline Guilbaud, Olivier Lowyck, Hajar Dahou, Antonella Mendola, Manon Desgres, Léo Aubert, Isabelle Gerin, Guido T. Bommer, Romain Boidot, Perrine Vermonden, Aurélien Warnant, Yvan Larondelle, Jean-Pascal Machiels, Olivier Feron, Sandra Schmitz, Cyril Corbet

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From skin to heart: The rare journey of pleomorphic dermal sarcoma metastasis by Maria Gabriela Matta, MD MSc, Dipesh Raniga, MD, Vinicius Carraro do Nascimento, MD, Gayle Therese Hill, BSc, Mohamed Nasser Essack, MD, Ian Agahari, MD

“…Despite clear surgical margins and adjuvant radiotherapy, he later exhibited metastatic disease affecting the lungs and heart. …”
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Gestational Choriocarcinoma Presenting with Lacrimal Gland Metastasis: A First Reported Case by Naushad A. B. Ahamed, Khalid Sait, Nisreen Anfnan, Khader Farwan, S. H. M. Nizamuddin, Saleh S. Baeesa

“…Based on her modified WHO risk factors scoring she was started on chemotherapy and whole brain radiotherapy, which resulted in a complete response. …”
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Supraclavicular Artery Island Flap in Head-and-neck Reconstruction: Our Experience by Abhinav Thaduri, Bhinyaram Jat, Amit Kumar, Amit Kumar Tyagi, Abhijeet Singh, Vikramjit Singh Kailey, Dileep Dungala Maharaj, Shahab Usmani, Kartikesh Gupta

“…Results: All patients underwent wide excision of the tumor following oncological principles, and four out of seven patients received postoperative adjuvant radiotherapy. Two patients with parotid tumors underwent facial skin excision along with total parotidectomy. …”
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Advances in Illuminating Prostate Cancer with Emerging Phototherapies by Ali Usman

“…Despite advancements in diagnostics and treatment options, conventional therapies for prostate cancer, including surgery, radiotherapy, chemotherapy and androgen deprivation therapy, face limitations such as treatment resistance, limited precision and off-target side-effects. …”
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MCNP-X Monte Carlo Code Application for Mass Attenuation Coefficients of Concrete at Different Energies by Modeling 3 × 3 Inch NaI(Tl) Detector and Comparison with XCOM and Monte C... by Huseyin Ozan Tekin

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Nonsmall Cell Lung Carcinoma with Giant Cell Features Expressing Programmed Death-Ligand 1: A Report of a Patient Successfully Treated with Pembrolizumab by Shingo Nakayama, Mamoru Sasaki, Shojiroh Morinaga, Naoto Minematsu

“…The patient received stereotactic radiotherapy for the brain metastases, followed by administration of pembrolizumab. …”
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Cerebral Metastasis from a Previously Undiagnosed Appendiceal Adenocarcinoma by Antonio Biroli, Paolo Cipriano Cecchi, Susanne Pragal, Esther Hanspeter, Andreas Schwarz

“…A right hemicolectomy was performed, and the specimen showed a moderately differentiated mucinous appendiceal adenocarcinoma. Whole brain radiotherapy was administrated. A subsequent thorax-abdomen CT scan revealed multiple lung and hepatic metastasis. …”
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Sesquiterpene Lactones as Promising Anti-Glioblastoma Drug Candidates Exerting Complex Effects on Glioblastoma Cell Viability and Proneural–Mesenchymal Transition by Andrey V. Markov, Arseny D. Moralev, Kirill V. Odarenko

“…Glioblastoma is one of the most aggressive brain cancers, characterized by active infiltrative growth and high resistance to radiotherapy and chemotherapy. Sesquiterpene triterpenoids (STLs) and their semi-synthetic analogs are considered as a promising source of novel anti-tumor agents due to their low systemic toxicity and multi-target pharmacological effects on key processes associated with tumor progression. …”
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Influential Factors and Synergies for Radiation-Gene Therapy on Cancer by Mei Lin, Junxing Huang, Yujuan Shi, Yanhong Xiao, Ting Guo

“…Radiation-gene therapy, a dual anticancer strategy of radiation therapy and gene therapy through connecting radiation-inducible regulatory sequence to therapeutic gene, leading to the gene being induced to express by radiation while radiotherapy is performed and finally resulting in a double synergistic antitumor effect of radiation and gene, has become one of hotspots in the field of cancer treatment in recent years. …”
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A Review of the Aetiopathogenesis and Clinical and Histopathological Features of Oral Mucosal Melanoma by Liviu Feller, Razia A. G. Khammissa, Johan Lemmer

“…Despite radical surgery, radiotherapy, or chemotherapy, local recurrence and distant metastasis are frequent. …”
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Do Pathologic Fractures in Long Bone Following Bony Malignancy Increase the Risk of Venous Thromboembolism? A Comparative Study by Sanjay Kumar Rai, Tej Pratap Gupta, Bhavya Sirohi, Surbhi Rajauria, Nitish Khandelwal

“…This risk of developing DVT is increased much fold in the presence of metastasis, chemotherapy, radiotherapy, fracture fixation, and arthroplasty.…”
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