Radiopharmaceuticals and their applications in medicine by Siqi Zhang, Xingkai Wang, Xin Gao, Xueyao Chen, Linger Li, Guoqing Li, Can Liu, Yuan Miao, Rui Wang, Kuan Hu

“…Abstract Radiopharmaceuticals involve the local delivery of radionuclides to targeted lesions for the diagnosis and treatment of multiple diseases. …”
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Unconventional Nuclides for Radiopharmaceuticals by Jason P. Holland, Matthew J. Williamson, Jason S. Lewis

“…Rapid and widespread growth in the use of nuclear medicine for both diagnosis and therapy of disease has been the driving force behind burgeoning research interests in the design of novel radiopharmaceuticals. Until recently, the majority of clinical and basic science research has focused on the development of 11 C-, 13 N-, 15 O-, and 18 F-radiopharmaceuticals for use with positron emission tomography (PET) and 99m Tc-labeled agents for use with single-photon emission computed tomography (SPECT). …”
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Imaging Gene Expression in Regional Brain Ischemia in Vivo with a Targeted [In]-Antisense Radiopharmaceutical by Toyofumi Suzuki, Yun Zhang, Yu-feng Zhang, Felix Schlachetzki, William M. Pardridge

“…The TfR MAb enables trans -membrane transport of the PNA antisense radiopharmaceutical from blood to the cytosol of brain cells. …”
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[18F]Tetrafluoroborate, a new NIS PET/CT radiopharmaceutical: an overview focused on differentiated thyroid cancer by Arnoldo Piccardo, Francesco Fiz, Sergio Righi, Stefano Raffa, Mattia Riondato, Gianluca Bottoni, Matteo Bauckneht, Michela Massollo, Alessio Rizzo, Mehrdad Shoushtari Zadeh Naseri, Pierpaolo Trimboli, Giorgio Treglia

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Personalized metronomic radiopharmaceutical therapy through injection profile optimization via physiologically based pharmacokinetic (PBPK) modeling by Aryan Golzaryan, M. Soltani, Farshad Moradi Kashkooli, Babak Saboury, Arman Rahmim

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Tryptophan Kynurenine Pathway-Based Imaging Agents for Brain Disorders and Oncology—From Bench to Bedside by Erik Stauff, Wenqi Xu, Heidi H. Kecskemethy, Sigrid A. Langhans, Vinay V. R. Kandula, Lauren W. Averill, Xuyi Yue

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Radiopharmacokinetic modelling and radiation dose assessment of 223Ra used for treatment of metastatic castration-resistant prostate cancer by Vera Höllriegl, Nina Petoussi-Henss, Kerstin Hürkamp, Juan Camilo Ocampo Ramos, Wei Bo Li

Subjects: “…Radiopharmaceutical…”
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Novel Chlorin with a HYNIC: Synthesis, ^99mTc-Radiolabeling, and Initial Preclinical Evaluation by Alexander Popov, Nikita Suvorov, Mariia Larkina, Evgenii Plotnikov, Ruslan Varvashenya, Vitalina Bodenko, Gleb Yanovich, Petr Ostroverkhov, Maxim Usachev, Elena Filonenko, Mikhail Belousov, Mikhail Grin

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Currents status of radiotracers for breast cancer imaging in PET by Chloé Jean, Stéphane Roux, Abdelilah Aziz, Maxence Mocquery-corre, Rana Bazzi, Yacine Merrouche, Stéphane Dedieu, Nicolas Etique, Dimitri Papathanassiou, Jérôme Devy

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Evaluation of maSSS/maSES-PEG2-RM26 for their potential therapeutic use after labeling with Re-188. Could their [99mTc]Tc-labeled counterparts be used to estimate dosimetry? by Panagiotis Kanellopoulos, Quanyi Yu, Abouzayed Abouzayed, Ekaterina Bezverkhniaia, Vladimir Tolmachev, Anna Orlova

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INTERNATIONAL ISOTOPES MARKETS by S. Z. Zhiznin, V. M. Timohov

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RevCAR-mediated T-cell response against PD-L1-expressing cells turns suppression into activation by Eugenia Crespo, Liliana R. Loureiro, Antonia Stammberger, Lydia Hoffmann, Nicole Berndt, Anja Hoffmann, Claudia Dagostino, Karla E. G. Soto, Luise Rupp, Claudia Arndt, Martin Schneider, Claudia R. Ball, Michael Bachmann, Marc Schmitz, Anja Feldmann

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Synthesis and in vitro evaluation of spirobenzovesamicols as potential 11C-PET tracer alternatives to [18F]FEOBV for vesicular acetylcholine transporter (VAChT) imaging by Hugo Helbert, Winnie Deuther-Conrad, Michel de Haan, Barbara Wenzel, Gert Luurtsema, Wiktor Szymanski, Peter Brust, Rudi A. J. O. Dierckx, Ben L. Feringa, Philip H. Elsinga

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Increasing brain half-life of antibodies by additional binding to myelin oligodendrocyte glycoprotein, a CNS specific protein by Marie-Lynn Cuypers, Tom Jaspers, Jarne Clerckx, Simon Leekens, Christopher Cawthorne, Guy Bormans, Frederik Cleeren, Nick Geukens, Bart De Strooper, Maarten Dewilde

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First-in-Human PET Imaging of [18F]SDM-4MP3: A Cautionary Tale by Kimberly L. Desmond, Anton Lindberg, Armando Garcia, Junchao Tong, Michael B. Harkness, Elena Dobrota, Kelly Smart, Carme Uribe, Jeffrey H. Meyer, Sylvain Houle, Antonio P. Strafella, Songye Li, Yiyun Huang, Neil Vasdev

“…[18F]SynVesT-1 is a PET radiopharmaceutical that binds to the synaptic vesicle protein 2A (SV2A) and serves as a biomarker of synaptic density with widespread clinical research applications in psychiatry and neurodegeneration. …”
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Development of an automated method for in-house production of sodium 18F-fluoride for injection: process validation as a step toward routine clinical application by Marija Atanasova Lazareva, Maja Chochevska, Katerina Kolevska, Maja Velickovska, Filip Jolevski, Paulina Apostolova, Ana Ugrinska, Emilija Janevik-Ivanovska

“…Process validation was carried according to GMP guidelines to ensure consistency of [18F]NaF quality with international standards. The final radiopharmaceutical met all quality criteria specified by Ph. …”
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Sentinel lymph nodes biopsy for malignant tumors using Technefit radioactive colloid Technetium 99mTc by Irina Onofriychuk, Aziz Zikiryahodzhaev, Anatoliy Ermakov, Nataliya Ablitsova, Eric Saribekyan, Elena Rasskazova, Gadgimurad Zapirov, Stanislav Mikhailov, Andrey Kaprin, Anna Sukhotko, Serghei Covantsev

“…Aim: The aim of the current study was to develop the technique of radiopharmaceutical preparation (RPP) of Technefit99mTc aimed at examining sentinel lymph nodes (SLN) before surgery. …”
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Radioimmunotherapy: A Specific Treatment Protocol for Cancer by Cytotoxic Radioisotopes Conjugated to Antibodies by Hidekazu Kawashima

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New Therapeutics to Treat Castrate-Resistant Prostate Cancer by Ömer Acar, Tarık Esen, Nathan A. Lack

“…In this review, we will examine mechanistic and clinical data of several newly approved therapeutics including the chemotherapeutic cabazitaxel, antiandrogen enzalutamide, endocrine disruptor abiraterone acetate, immunotherapy sipuleucel-T, and bone-targeting radiopharmaceutical alpharadin. In addition, we will examine other promising therapeutics that are currently in Phase III trials.…”
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Imaging in Periprosthetic Joint Infection Diagnosis: A Comprehensive Review by Armin Hoveidaei, Yasaman Tavakoli, Mohammad Reza Ramezanpour, Mahyaar Omouri-kharashtomi, Seyed Pouya Taghavi, Amir Human Hoveidaei, Janet D. Conway

“…Each imaging technique and radiopharmaceutical has been extensively studied, with unique diagnostic accuracy, limitations, and benefits for PJI diagnosis. …”
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