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Mutant Fam20c knock-in mice recapitulate both lethal and non-lethal human Raine Syndrome
Published 2025-01-01“…The Fam20c D446N allele replaced the WT Fam20c by 3.6Kb Col1a1-Cre to get the conditional knock-in mice, and by Hprt-cre to get conventional knock-in mice, respectively. Results The radiology, serum biochemistry and immunohistochemistry indicated that all conditional and most conventional Fam20c D446N knock-in mice displayed hypophosphatemic rickets with the increased Fgf23 and deceased Dmp1 expression, which survived to adulthood. …”
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Gut microbiome-derived bacterial extracellular vesicles in patients with solid tumours
Published 2025-02-01Get full text
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Adherent junctions: Physiology, role in hydrocephalus and potential therapeutic targets
Published 2025-06-01Get full text
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Analysis of panel physician inquiries to U.S. TB Centers of Excellence, 2018–2022
Published 2024-11-01“…Diagnostic questions (n = 104, 48.4%) included mycobacterial culture, smear, and radiology interpretation. Treatment tailoring inquiries involved optimizing the initial regimen (n = 89, 41.4%) or modifying existing regimens (n = 26, 12.1%). …”
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