Study of the neuroprotective properties of metformin in rats with type 2 diabetes mellitus and brain injury induced by intracerebral hemorrhage by V.L. Holubiev, M.H. Oberemok, V.A. Tkachenko, Yu.V. Kharchenko, O.O. Bondarenko, A.E. Lievykh, V.I. Zhyliuk

“…In this study, metformin had nootropic (anti-amnestic) activity and decreased oxidative stress markers (AGEs, AOPPs and 8-OHdG) levels by 29.1% (p<0.001), 24.9% (p<0.015) and 29.3% (p<0.05) respectively, which indicates its positive impact on the course of free radical oxidation reactions intensified by both diabetes and intracerebral hemorrhage. …”
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Germline Single-Nucleotide Polymorphism <i>GFI1-36N</i> Causes Alterations in Mitochondrial Metabolism and Leads to Increased ROS-Mediated DNA Damage in a Murine Model of Human Acu... by Jan Vorwerk, Longlong Liu, Theresa Helene Stadler, Daria Frank, Helal Mohammed Mohammed Ahmed, Pradeep Kumar Patnana, Maxim Kebenko, Eva Dazert, Bertram Opalka, Nikolas von Bubnoff, Cyrus Khandanpour

“…<b>Results</b>: Following the isolation of leukemic bone marrow cells, we were able to show that the <i>GFI1-36N</i> SNP in our model is associated with enhanced oxidative phosphorylation (OXPHOS), increased ROS levels, and results in elevated γ-H2AX levels as a marker of DNA double-strand breaks (DSBs). The use of free radical scavengers such as N-acetylcysteine (NAC) and α-tocopherol (αT) reduced ROS-induced DNA damage, particularly in <i>GFI1-36N</i> leukemic cells. …”
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Valorisation of shell waste of invasive crayfish from Danube River (Faxonius limosus): Protein extraction and characterization by Hromiš Nevena M., Popović Senka Z., Šuput Danijela Z., Pantić Jovana R., Rakita Slađana M., Tomičić Zorica M., Čabarkapa Ivana S.

“…The obtained protein concentrates were analysed for yield, crude protein content, DPPH radical scavenging ability, amino acid content, and structure. …”
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Protocol for a randomised phase 3 trial evaluating the role of Finasteride in Active Surveillance for men with low and intermediate-risk prostate cancer: the FINESSE Study by Samuel Smith, Peter Sasieni, William Cross, Richard Bryant, Steven Kennish, James Catto, Rachel Hubbard, Simon Faulkner, Rohit Chahal, Mohantha Dooldeniya, Marcus Cumberbatch, Bernard North, Alastair D Lamb, Roseann Kealy, Selina Bhattrai

“…While AS reduces overtreatment (and quality of life impact), long-term compliance can be poor, with many men undergoing radical treatment after starting AS.Methods and analysis Finasteride in Active Surveillance for men with low and intermediate-risk prostate cancer (FINESSE) is a prospective, open-label, two-arm, phase 3 trial, in which men with low or intermediate PCa are randomised (1:1) to receive AS with or without finasteride (5 mg once a day for 2 years). …”
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Robotic versus laparoscopic surgery for severe deep endometriosis: protocol for a randomised controlled trial (ROBEndo trial) by Tero Rautio, Pasi Ohtonen, Outi Uimari, Anna Maria Terho, Johanna Mäkelä-Kaikkonen, Terhi Puhto, Sari Koivurova

“…Patients with deep endometriosis verified by MRI needing surgery at Oulu University Hospital (Oulu, Finland) will be considered eligible. 70 patients will be allocated 1:1 to receive either robotic-assisted or conventional laparoscopic surgery in two strata: radical surgery (with the removal of the uterus and adnexae) and gynaecological organ-sparing surgery. …”
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Una nueva estrategia integral para modelar materiales urbanos para ciudades térmicamente habitables. Un caso de estudio en Madrid = A new integrated strategy for modelling urban ma... by Emanuela Giancola, Helena López, Silvia Soutullo, M. Nuria Sánchez, Luis F. Zarzalejo, Ana Gamarra, Israel Herrera, J. Antonio Ferrer, Emanuele Naboni

“…Abstract From a thermal point of view, the use of multifunctional and innovative materials in urban surfaces can provide radical improvements and reduce the Urban Heat Island effect. …”
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O2-self-supplying and glutathione-depleting scaffold for synergistic cancer therapy by Jiajia Zeng, Chongxian He, Xinna Bai, Cijun Shuai, Hao Pan

“…The results indicated that the concentration of oxygen in PLLA/Ti3C2-CeO2 scaffold group was 9.76 mg/L higher, and the concentration of singlet oxygen (1O2) and hydroxyl radical (·OH) was respectively increased by 60 % and 170 %, compared with the PLLA/Ti3C2 scaffold. …”
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Phytochemical Characterization and Biological Activity of Two <i>Anacardiaceae</i> Species from Guinea-Bissau by Quintino Malú, Maryam Malmir, Gonçalo Infante Caldeira, Sofia Encarnação, Katelene Lima, Luís Catarino, Beatriz Silva Lima, João Rocha, Olga Silva

“…The anti-inflammatory effects were evaluated using a rat model of induced paw edema, while the antioxidant activity was evaluated by DPPH^• radical scavenging and iron-reducing antioxidant power assays. …”
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Unveiling <i>DENND2D</i> as a Novel Prognostic Biomarker for Prostate Cancer Recurrence: From Gene to Prognosis by Chi-Fen Chang, Lih-Chyang Chen, Yei-Tsung Chen, Chao-Yuan Huang, Chia-Cheng Yu, Victor C. Lin, Te-Ling Lu, Shu-Pin Huang, Bo-Ying Bao

“…<b>Background:</b> Prostate cancer is a major global health burden, with biochemical recurrence (BCR) following radical prostatectomy affecting 20–40% of patients and posing significant challenges to prognosis and treatment. …”
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Cytoreductive Nephrectomy and Nephrectomy/Complete Metastasectomy for Metastatic Renal Cancer by Paul Russo, Mark Synder, Andrew Vickers, Varuni Kondagunta, Robert Motzer

“…During this time frame, 1628 patients underwent nephrectomy (partial or radical) for renal masses, 91 (5.6%) of whom had metastatic disease. …”
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Combined effects of alginate based active edible coatings and irradiation treatment on the quality characteristics of Beef Meat at 2°C by Samir Smeti, Souha Tibaoui, Hayet Ben Haj Koubaier, Atef Lakoud, Naziha Atti

“…MYRT and ROS samples had the highest free radical scavenging activity (P<0.001) with an inhibition capacity of around 64.8 and 62.7%, respectively. …”
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Biofabrication of copper oxide nanoparticles using Dalbergia sisso leaf extract for antibacterial, antibiofilm and antioxidant activities by Muhammad Hussnain Siddique, Maimona Sadia, Saima Muzammil, Muhammad Saqalein, Asma Ashraf, Sumreen Hayat, Saba Saba, Arif Muhammad Khan, Abeer Hashem, Graciela Dolores Avila-Qezada, Elsayed Fathi Abd-Allah

“…In vitro antioxidant activity of fabricated nanoparticles revealed significant antioxidant potential (p < 0.05) by quenching free radicals such as DPPH (73.6%), ABTS (68%) and H2O2 (63%) in a dose-dependent manner.…”
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Metabolite profile and antioxidant activities of Trikatu, black pepper, Javanese long pepper, and red ginger essential oils by Dewa Ayu Ika Pramitha, Tati Herlina, Iman Permana Maksum, Ari Hardianto, Abd. Wahid Rizaldi Akili, Jalifah Latip

“…Antioxidant activities of TR, BP, JLP, and RG essential oils was determined using the DPPH free radical scavenging assay. Results: The GC–MS analysis of BP, JLP, RG, and TR essential oils revealed the presence of 11 common compound, including linalool, caryophyllene, and beta-bisabolene. …”
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OCT Biomarkers in Neovascular Age-Related Macular Degeneration: A Narrative Review by Cristian Metrangolo, Simone Donati, Marco Mazzola, Liviana Fontanel, Walter Messina, Giulia D’alterio, Marisa Rubino, Paolo Radice, Elias Premi, Claudio Azzolini

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THE INSTITUTIONALIZATION OF GLOBAL STRATEGIES FOR THE TRANSFORMATION OF SOCIETY AND EDUCATION IN THE CONTEXT OF CRITICAL THEORY by Viktor V. Zinchenko

“…Critical social philosophy of education strives to provide a radical critique of existing models of education in the so-called Western models of democracy, creating progressive alternative models. …”
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Gross recurrent laryngeal nerve invasion by extranodal extension in thyroid carcinoma by Xin Li, Xiang-yun Yao, Shi-rong Liu, Fang Mei, Bo Yu, Bing-yan Wang, Shi-bing Song, Shi Tan

“…Careful central compartment evaluation for patients with lymphatic metastases from thyroid carcinoma is conducive to nerve preservation and radical resection of lesions, especially for patients with MTC.…”
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METODOLOGINIAI INFORMACIJOS VISUOMENĖS STUDIJŲ PROFILIAI: VYNAS JAUNAS, VYNMAIŠIAI SENI? by Marius Povilas Povilas Šaulauskas

“…It is argued that, taken as a whole, even the most radical information society theories, insisting on the post-modern "Age of Information", pour old wine (i.e. traditional assembly of methodological instrumentation, devised to tackle with explicitly modern societal change) into new wineskins (i.e. new previously unseen societal morphology ex definition requiring equally unique conceptual apparatus). …”
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Radiation-assisted tailoring of swelling behavior and water retention of Na-CMC/PAAm hydrogels for enhancing Beta Vulgaris under drought stress by Mahmoud A. El-diehy, Ibrahim I. Farghal, Mohamed A. Amin, Mohamed Mohamady Ghobashy, Abdelatti I. Nowwar, H. M. Gayed

“…Gamma radiation-induced free radical copolymerization was used to synthesize superabsorbent hydrogels using sodium carboxymethyl cellulose (Na-CMC) and acrylamide (AAm). …”
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Snack products from whole-grain red sorghum flour with paprika and cocoa powders by Janić-Hajnal Elizabet, Banjac Vojislav, Filipčev Bojana, Radić Bojana, Kos Jovana, Šimurina Olivera, Cvetković Biljana

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UM CINEMA À MARGEM by Paulo Marcondes Ferreira Soares

“…Os modelos escolhidos apontam, de um lado, para um realismo radical, que assume uma ideia de estrutura fílmica documental que seja reveladora da estrutura social tal qual supostamente ela e. …”
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