Adaptive Neuro-Fuzzy Inference System guided objective function parameter optimization for inverse treatment planning by Eduardo Cisternas Jiménez, Fang-Fang Yin, Fang-Fang Yin, Fang-Fang Yin

“…This study presents a proof-of-concept artificial intelligence (AI) system based on an Adaptive Neuro-Fuzzy Inference System (ANFIS) to guide IMRT planning and achieve optimal, patient-specific prescriptions in aligned with a radiation oncologist's treatment objectives. We developed an in-house ANFIS-AI system utilizing Prescription Dose (PD) constraints to guide the optimization process toward achievable prescriptions. …”
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Preliminary efficacy and safety analysis: 12-month results in 83 patients using a novel approach of widefield radiation therapy for extensive skin field cancerization with or witho... by Andrew E. Potter, Christopher Baker, Stephen Shumack, Robert Sinclair, Walter J. Curran, David Christie, Bradley Wong, Peter Foley, Peter O’Brien, Lynda Spelman

“…Purpose Evaluate the use of widefield radiation therapy (RT) in the management of extensive skin field cancerization (ESFC) with/without keratinocyte cancer (KC).Methods The National Dermatology Radiation Oncology Registry is a multidisciplinary collaboration (dermatologists and radiation oncologists). It captures disease description, prior therapies, radiation prescription, clinical effect, skin cosmesis scores, and toxicity data. …”
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Training for tomorrow: Establishing a worldwide curriculum in online adaptive radiation therapy by Meegan Shepherd, Elizabeth Joyce, Bethany Williams, Siobhan Graham, Winnie Li, Jeremy Booth, Helen A. McNair

“…A global shortage of skilled radiation professionals such as radiation therapists or therapeutic radiographers (RTTs), medical physicists and radiation oncologists, along with training challenges in online adaptive techniques, hinders oART implementation and sustainability. …”
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Dose-volume parameter evaluation of a sub-fractionation workflow for adaptive radiotherapy of prostate cancer patients on a 1.5 T magnetic resonance imaging radiotherapy system by Georgios Tsekas, Cornel Zachiu, Gijsbert H. Bol, Jochem R.N. van der Voort van Zyp, Sandrine M.G. van de Pol, Johannes C.J. de Boer, Bas W. Raaymakers

“…The deformed prostate contours were inspected by radiation oncologists and corrections were performed when necessary. …”
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Radiation dose and fraction in immunotherapy: one-size regimen does not fit all settings, so how does one choose? by Marka Crittenden, Sandra Demaria, C Norman Coleman, Jonathan Schoenfeld, Arta Monjazeb, Samir Khleif, Seema Gupta, Andrew Sikora, Zachary Morris, Chandan Guha, Stephen Shiao, Silvia Chiara Formenti, Bhadrasain Vikram, Mansoor M Ahmed

“…Hence, these differences in radiotherapy fractionation result in distinct immune-modulatory effects. Radiation oncologists and immunologists convened a virtual consensus discussion to identify current deficiencies, challenges, pitfalls and critical gaps when combining radiotherapy with immunotherapy and making recommendations to the field and advise National Cancer Institute on new directions and initiatives that will help further development of these two fields.This commentary aims to raise the awareness of this complexity so that the need to study radiation dose, fractionation, type and volume is understood and valued by the immuno-oncology research community. …”
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