Showing 21 - 40 results of 93 for search '"RNA interference"', query time: 0.05s Refine Results
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    Prospect of Induced Pluripotent Stem Cell Genetic Repair to Cure Genetic Diseases by Jeanne Adiwinata Pawitan

    Published 2012-01-01
    “…This review discusses the various technologies to repair the genetic aberration in patient-derived iPSC, or to prevent the genetic aberration to cause further damage in the iPSC-derived cells, such as Zn finger and TALE nuclease genetic editing, RNA interference technology, exon skipping, and gene transfer method. …”
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  12. 32

    Innovative Approaches to Suppressing Pseudomonas aeruginosa Growth and Virulence: Current Status and Future Directions by Sandip Patil, Xiaowen Chen, Feiqiu Wen

    Published 2024-01-01
    “…Additionally, novel approaches, including RNA interference, CRISPR-Cas systems, and nanotechnology, show promise in preclinical studies. …”
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  13. 33

    Loss of Type 2 Bone Morphogenetic Protein Receptor Activates NOD‐Like Receptor Family Protein 3/Gasdermin E‐Mediated Pyroptosis in Pulmonary Arterial Hypertension by Xiao‐ting Tian, Zhou‐yang‐fan Peng, Yu‐si Wu, Yuan‐yuan Cao, Xue‐chun Li, Ying Li, Si‐Yuan Tang, Alex F. Chen, Xiao‐hui Li

    Published 2025-02-01
    “…METHODS AND RESULTS NLRP3 knockout or short hairpin RNA interference of GSDME was performed in PAH animal models to investigate its effect on PAH progression. …”
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  14. 34

    Suppression of the Oncogenic Transcription Factor FOXM1 by Proteasome Inhibitors by Andrei L. Gartel

    Published 2014-01-01
    “…We generated isogenic human cancer cell lines of different origin with wild-type p53 or p53 knockdown and we demonstrated that proteasome inhibitors induce p53-independent apoptosis in these cells. Using RNA-interference or proteasome inhibitors to inhibit FOXM1 we found that suppression of FOXM1 sensitized human cancer cells to apoptosis induced by DNA-damaging agents or oxidative stress. …”
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  15. 35

    GENETIC AND MOLECULAR ANALYSIS OF COMPLEMENTATION OF THE FLAMENCO AND PIWI LOCI IN DROSOPHILA MELANOGASTER by F. A. Urusov, L. N. Nefedova, A. R. Lavrenov, N. I. Romanova, A. I. Kim

    Published 2015-01-01
    “…Piwi is the primary component of the RNA interference machinery. Mutations in piwi and flamenco have the same phenotype – an enhanced transcription and frequency of transposition of the retrotransposon/retrovirus gypsy. …”
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  16. 36

    Inotersen to Treat Polyneuropathy Associated with Hereditary Transthyretin (hATTR) Amyloidosis by Christopher Robinson, Cynthia Pham, Alec M. Zamarripa, Chase S. Dugay, Christopher A. Lee, Amnon A. Berger, Avi Landman, Elyse M. Cornett, Hisham Kassem, Alan D. Kaye, Ivan Urits, Omar Viswanath, Latha Ganti

    Published 2023-01-01
    “…Novel therapeutic options are groundbreaking by providing disease-modifying specific, targeted therapies against TTR production and deposition. The use of RNA interference (RNAi) opens the door to the treatment of hereditary diseases by targeting them at the genetic level.…”
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  17. 37

    Dendrimers as Carriers for siRNA Delivery and Gene Silencing: A Review by Jiangyu Wu, Weizhe Huang, Ziying He

    Published 2013-01-01
    “…RNA interference (RNAi) was first literaturally reported in 1998 and has become rapidly a promising tool for therapeutic applications in gene therapy. …”
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    Advancements in Cardiac Amyloidosis Treatment by Tarek Ziad Arabi, Abdullah Shaik, Ahmed El-Shaer, Omar Al Tamimi, Eman Nayaz Ahmed, Mohamad S. Alabdaljabar, Ahmad Safdar, Ali Mushtaq

    Published 2024-12-01
    “…Treatment has evolved significantly with targeted therapies like TTR stabilizers, gene silencers, and RNA interference, showing promise in altering disease progression. …”
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  19. 39

    FRUIT DAMAGES CAUSED BY BROWN MARMORATED STINK BUGS IN APPLES AND QUINCES by Attila Keseru, Flavia-Andreea Andrecan, Horia Alexandru Pop, Mihai Buta, Orsolya Borsai

    Published 2024-12-01
    “…Proposed measures include monitoring pest populations, deploying biological controls such as Trissolcus japonicus, and exploring RNA interference-based approaches to mitigate crop losses caused by this polyphagous pest.…”
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  20. 40

    A new crustin-like gene from the redclaw crayfish Cherax quadricarinatus and its response to decapod iridescent virus 1 (DIV1) challenge by Xiaoying Hang, Jianbo Zheng, Fei Li

    Published 2025-01-01
    “…Moreover, RNAi-mediated gene silencing of Cqcarc1 could increase the DIV1 copy number compared with the control group, suggesting its involvement in the immune defense against the DIV1 challenge. Furthermore, RNA interference analysis also showed that Cqcarc1 plays positive regulatory roles in the expressions of CqToll and CqCrs during DIV infection. …”
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