Biomolecular Triconjugates Formed between Gold, Protamine, and Nucleic Acid: Comparative Characterization on the Nanoscale by Robert K. DeLong, Lisa Cillessen, Chris Reynolds, Adam Wanekaya, Tiffany Severs, Kartik Ghosh, Michael Fisher, Stephanie Barber, John Black, Ashley Schaeffer, Kristin J. Flores

“…DNA and RNA micro- and nanoparticles are increasingly being used for gene and siRNA drug delivery and a variety of other applications in bionanotechnology. …”
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YTHDF2 mediates the protective effects of MG53 on myocardial infarction injury via recognizing the m6A modification of MG53 by Zhaojie Li, Kai Li, Jianqiang Zhao

“…Furthermore, N6-methyl-adenosine (m6A) methylation is a mode of RNA modification that influences mRNA functions. …”
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Natalizumab Treatment Modulates Peroxisome Proliferator-Activated Receptors Expression in Women with Multiple Sclerosis by Véronique Ferret-Sena, Alexandra Maia e Silva, Armando Sena, Inês Cavaleiro, José Vale, Bruno Derudas, Giulia Chinetti-Gbaguidi, Bart Staels

“…At three months, NTZ increased PPARβ/δ mRNA (p=0.009) in comparison to baseline, while mRNA expression of PPARγ and CD36 (a well-known PPAR target gene) was lower in comparison to healthy controls (p=0.026 and p=0.028, resp.). …”
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Evaluation for Retinal Therapy for RPE65 Variation Assessed in hiPSC Retinal Pigment Epithelial Cells by Benjamin M. Nash, To Ha Loi, Milan Fernando, Amin Sabri, James Robinson, Anson Cheng, Steven S. Eamegdool, Elizabeth Farnsworth, Bruce Bennetts, John R. Grigg, Seo-Kyung Chung, Anai Gonzalez-Cordero, Robyn V. Jamieson

“…Sequencing of RNA obtained from hiPSC-RPE cells demonstrated heterozygous skipping of RPE65 exon 2 and the introduction of a premature stop codon in the mRNA. …”
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Molecular detection of Escherichia coli from ovine aborted fetuses in Mosul city, Iraq by Aamer Y. Al-Chalaby, Omer K. Alhankawe, Balsam Y. Rasheed

“…The isolates that targeted the 23SrRNA gene were verified using PCR. Additionally, specialized primers for the uidA and zapA genes were used. …”
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Effect of vasopressin on the expression of genes for key enzymes of interstitial hyaluronan turnover and concentration ability in WAG rat kidneys by L. N. Ivanova, A. V. Babina, G. S. Baturina, L. E. Katkova

“…The V2 receptor-selective vasopressin analog dDAVP (100 μg/kg bw, ip, twice a day for 2 days) induced a considerable decrease in Has2 mRNA content in the papilla with less pronounced changes in the cortex. …”
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Do Salivary <i>Cullin7</i> Gene Expression and Protein Levels Provide Advantages over Plasma Levels in Diagnosing Breast Cancer? by Ceren Tilgen Yasasever, Derya Duranyıldız, Süleyman Bademler, Hilal Oğuz Soydinç

“…Considering the possibility of Cul7 being a biomarker at the protein and mRNA levels, plasma is thought to be a better study material for Cul7. …”
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Morphological and phylogenetic analyses reveal two new species of the Fusarium fujikuroi (Hypocreales, Nectriaceae) species complex in China by Mingwei Zhang, Cheng Peng, Shuji Li, Chengming Tian

“…We employ morphological and phylogenetic analyses based on partial gene fragments of the translation elongation factor 1-alpha (tef1), beta-tubulin (tub2), calmodulin (CaM), RNA polymerase largest subunit (rpb1), and RNA polymerase II second largest subunit (rpb2), as well as the pairwise homoplasy index tests. …”
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Current Research Progress on Long Noncoding RNAs Associated with Hepatocellular Carcinoma by Haihong Shi, Yuxin Xu, Xin Yi, Dandan Fang, Xia Hou

“…Here, we review the regulation and function of lncRNA in liver cancer and evaluate the potential of lncRNA as a new goal for liver cancer.…”
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Artificial cells with all-aqueous droplet-in-droplet structures for spatially separated transcription and translation by Kanji Tomohara, Yoshihiro Minagawa, Hiroyuki Noji

“…The inner droplet is designed to enrich DNA and RNA polymerase for transcription, coupled to translation at the outer droplet via mRNA-mediated cascade reactions. …”
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François Gros (1925–2022) by Petit, Christine, Kourilsky, Philippe

“…In 1961, he discovered the molecular nature of the proposed intermediary between the gene and the protein, a so-called messenger RNA (mRNA), and determined its main characteristics. …”
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R-Loop Formation In Trans at an AGGAG Repeat by Kazuya Toriumi, Takuma Tsukahara, Ryo Hanai

“…Formation of RNA-DNA hybrid, or R-loop, was studied in vitro by transcribing an AGGAG repeat with T7 RNA polymerase. …”
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Sequences of acetyl CoA carboxylase promoter for tumour necrosis factor action by Keerang Park, Michael E. Pape, Ki-Han Kim

“…Tumour necrosis factor (TNF) inhibits the accumulation of acetyl CoA carboxylase (ACC) mRNA by decreasing the rate of ACC gene transcription. …”
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Aberrant MicroRNAs in Pancreatic Cancer: Researches and Clinical Implications by Tao Sun, Xiangyu Kong, Yiqi Du, Zhaoshen Li

“…Numerous studies have proved that microRNA (miRNA) may play a vital role in a wide range of malignancies, including PDAC, and dysregulated miRNAs, including circulating miRNAs, are associated with PDAC proliferation, invasion, chemosensitivity, and radiosensitivity, as well as prognosis. …”
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Failure of Ketoprofen and Interferon Combination Therapy to Improve Interferon-Resistant Chronic Hepatitis C by Frank H Anderson, Lecheng Zeng, Eric M Yoshida, Natalie R Rock

“…Serum aminotransferases (alanine aminotransferase [ALT] and aspartate aminotransferase [AST]) and serum hepatitis C virus (HCV) RNA were analyzed before and throughout treatment. …”
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Aspergillus section Versicolores: nine new species and multilocus DNA sequence based phylogeny by Z. Jurjevic, S.W. Peterson, B.W. Horn

“…β-tubulin, calmodulin, internal transcribed spacer and partial lsu-rDNA, RNA polymerase 2, DNA replication licensing factor Mcm7, and pre-rRNA processing protein Tsr1 were amplified and sequenced from numerous isolates belonging to Aspergillus sect. versicolor. …”
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Detection of Antibody to Envelope (E2) Antigen of Hepatitis C Virus by RK Chaudhary, E Burres

“…Eight of 12 (67%) indeterminate, HCV RNA positive samples were anti-E2 reactive. Nine of 30 (30%) indeterminate, HCV RNA negative samples were also positive for anti-E2. …”
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The microenvironment cell index is a novel indicator for the prognosis and therapeutic regimen selection of cancers by Xian-Yan Yang, Nian Chen, Qian Wen, Yu Zhou, Tao Zhang, Ji Zhou, Cheng-Hui Liang, Li-Ping Han, Xiao-Ya Wang, Qing-Mei Kang, Xiao-Xia Zheng, Xue-Jia Zhai, Hong-Ying Jiang, Tian-Hua Shen, Jin-Wei Xiao, Yu-Xin Zou, Yun Deng, Shuang Lin, Jiang-Jie Duan, Jun Wang, Shi-Cang Yu

“…Single-cell RNA sequencing (scRNA-seq), spatially resolved transcriptomics (SRT), and multiplex immunofluorescence (mIF) staining analyses verified MCI. …”
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Altered Atlas of Exercise-Responsive MicroRNAs Revealing miR-29a-3p Attacks Armored and Cold Tumors and Boosts Anti-B7-H3 Therapy by Jie Mei, Zhiwen Luo, Yun Cai, Renwen Wan, Zhiwen Qian, Jiahui Chu, Yaying Sun, Yuxin Shi, Ying Jiang, Yan Zhang, Yongmei Yin, Shiyi Chen

“…Mechanistically, miR-29a-3p targeted macrophages, fibroblasts, and tumor cells to down-regulate B7 homolog 3 (B7-H3) expression. Single-cell RNA sequencing (scRNA-seq) and cytometry by time-of-flight (CyTOF) demonstrated that miR-29a-3p attacked the armored and cold tumors, thereby shaping an immuno-hot tumor microenvironment (TME). …”
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Efficacy and safety of SHEN26, a novel oral small molecular RdRp inhibitor for COVID-19 treatment: a multicenter, randomized, double-blinded, placebo-controlled, phase II clinical... by Jiangtao Bai, Tetsuya Asakawa, Wenfang Yuan, Yuanlong Lin, Hao Ju, Dandan Xu, Mingming Yang, Shuo Li, Guanguan Li, Deyin Guo, Hongzhou Lu, Xumu Zhang

“…Abstract Background SHEN26 (ATV014) is an oral RNA-dependent RNA polymerase (RdRp) inhibitor with potential anti-SARS-CoV-2 activity. …”
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