Effects of the Replacement of Dietary Fishmeal by the Blend of Tenebrio molitor Meal, Chlorella Meal, Clostridium Autoethanogenum Protein, and Cottonseed Protein Concentrate on Gro... by Yongning Yu, Xing Wang, Junyan Jin, Dong Han, Xiaoming Zhu, Haokun Liu, Zhimin Zhang, Yunxia Yang, Shouqi Xie

“…The 100% substitution of FM with BLEND A significantly upregulated the mRNA expression of intestinal proinflammatory cytokines and downregulated the mRNA expression of anti-inflammatory cytokine il-10 (P <0.05), reduced intestinal villus height (P<0.05), and decreased protein apparent digestibility coefficient (P<0.05). …”
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Characterization and functional analysis of chicken hnRNP protein by Ke Wang, Manzi Huang, Qinghua Zeng, Huansheng Wu

“…In this study, multiple chicken hnRNPs were identified to interact with genomic dsRNA. Initially, these hnRNPs were found to be exclusively localized in the nucleus before IBDV infection. …”
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Plasma miRNAs in polycystic ovary syndrome drive endometrial cancer progression: insights into molecular pathways and therapeutic targets by Xuedan Lai, Ling Wu, Peihong Lin, Lijiao You, Jianwen Ye

“…MicroRNAs (miRNAs) could provide insights into these mechanisms and reveal potential therapeutic targets. Differential miRNA expression was analyzed in plasma exosomes from 15 PCOS and 15 control samples. …”
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miR663 Prevents Epo Inhibition Caused by TNF-Alpha in Normoxia and Hypoxia by Mete Ozkurt, Thomas Hellwig-Bürgel, Reinhard Depping, Selda Kadabere, Rumeysa Ozyurt, Abdullah Karadag, Nilüfer Erkasap

“…Then, we performed the microRNA array study with TNF-α (20 ng/ml)-treated cells, and the array results were confirmed by qRT-PCR. …”
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Angesinenolide B, A Phthalide Dimeric Peroxide, Exerts Anti-Inflammatory Properties by Suppressing MAPK/STATs Signaling Pathways and ROS Production by Zhang L, Liu Y, Wang H, Guo S, Lv J

“…In vivo, ROS generation was explored using fluorescent probe DCFH-DA, and the TNF-α and IL-6 mRNA expressions were also evaluated in CuSO4-induced zebrafish inflammation model.Results: ASB treatment was found to suppress the levels of NO, TNF-α, IL-6 and ROS, restrain the expressions of iNOS and COX-2 proteins and mRNA, as well as down-regulate MAPK and STATs signaling pathways in LPS-stimulated RAW264.7 cells. …”
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Myotubularin-Related Phosphatase 3 Promotes Growth of Colorectal Cancer Cells by Bo’an Zheng, Xiaojun Yu, Rui Chai

“…In the present study, we aimed to investigate the role of myotubularin-related phosphatase 3 (MTMR3) in CRC cell growth via lentivirus-mediated small interfering RNA (siRNA) transduction in human colon cancer cell lines HCT116 and SW1116. …”
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Quantitative DIA-based proteomics unveils ribosomal biogenesis pathways associated with increased final size in three-year-old Chinese mitten crab (Eriocheir sinensis) by Qing Li, Chuanlong Ge, Lijuan Li

“…Results The analysis revealed that differentially expressed proteins were predominantly enriched in essential cellular processes such as ribosome, ribosome biogenesis, RNA degradation, proteasome, mRNA surveillance pathway, and RNA biogenesis. …”
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Comparative analysis of mitochondrial genomes from Buthidae (Scorpiones): gene rearrangement and phylogenetic implications by Wei Xu, Gaoji Zhang, Tangjun Xu, Ke He, Jiachen Wang, Zeyang Liu, Hongyi Liu

“…Our analyses provide additional evidence on that, in scorpions, the majority of mitogenome rearrangements occurred in tRNAs. Moreover, the genes tRNA-Asp, tRNA-Gln and tRNA-Ile were the hotspots of rearrangement in this order. …”
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Differentially Expressed microRNAs in Peritoneal Dialysis Effluent-Derived Exosomes from the Patients with Ultrafiltration Failure by Weifei Wu, Xu Wu, Zhiqun Cheng, Zhenzhen Yang, Minhui Lu, Jing Cheng

“…This study aimed to characterize the circulating exosomal microRNA (miRNA) profiles associated with ultrafiltration failure and explore its underlying mechanisms. …”
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The first complete mitochondrial genome of Sumatran striped rabbit Nesolagus netscheri (Schlegel, 1880), and its phylogenetic relationship with other Leporidae by Dwi Sendi Priyono, Nayla Rafina, Tuty Arisuryanti, Indra Lesmana, Indra Yustian, Arum Setiawan

“…The mitochondrial genome of N. netscheri contained 22 transfer RNA (tRNA) genes, and all tRNA except for trnS1 showed a characteristic cloverleaf secondary structure. …”
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xCT as a potential marker for neuroendocrine cells in high-risk prostate cancer and the relation to AL122023.1-miR-26a/30d/30e axis. by Elena D Wilhelm, Jaroslaw T Dankert, Marc Wiesehöfer, Sven Wach, Mathias Wagner, Martin Spahn, Marianna Kruithof-de Julio, Gunther Wennemuth

“…Furthermore, xCT is known to be a putative target for miRNAs miR-26a, miR-30d and miR-30e, which in turn potentially interact with AL122023.1. The lncRNA-miRNA-interaction was verified by luciferase reporter assays. …”
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Proinflammatory Cytokines Increase Vascular Endothelial Growth Factor Expression in Alveolar Epithelial Cells by James P. Maloney, Li Gao

“…TNF-α increased VEGF RNA as early as 1 hour. A mix of IL-1, IL-6, and IL-8 had effects similar to IL-1. …”
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Fasting Upregulates PPAR𝛼 Target Genes in Brain and Influences Pituitary Hormone Expression in a PPAR𝛼 Dependent Manner by Bettina König, Christine Rauer, Susann Rosenbaum, Corinna Brandsch, Klaus Eder, Gabriele I. Stangl

“…Furthermore, pituitary prolactin and luteinizing hormone-𝛽 mRNA concentrations were increased upon fasting in wild-type mice but not in mice lacking PPAR𝛼. …”
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Homology Modeling and Expression of Recombinant NS5-RdRp Based on the Indonesian Local Strain of Dengue Virus for Anti-Dengue Drug Development by Toto Subroto, Ade Rizqi Ridwan Firdaus, Shinta Kusumawardani, Taufik Ramdani Tohari, Theresia Adventina Nababan, Wulan Pertiwi, Muhammad Fadhlillah, Sri Agung Fitri Kusuma, Yaya Rukayadi

“… This study aims to isolate the RNA-dependent RNA polymerase (RdRp) gene of the dengue virus (DENV) isolates from Indonesia, determine the serotype of the local DENV strain through homology modeling, and express the recombinant RdRp protein in Escherichia coli BL21 (DE3), as the target for anti-dengue drug development. …”
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Carbon Monoxide-Releasing Molecule-3 Suppresses Tumor Necrosis Factor-α- and Interleukin-1β-Induced Expression of Junctional Molecules on Human Gingival Fibroblasts via the Heme Ox... by Jia Lv, Yongsheng Liu, Shuhan Jia, Yuna Zhang, Haoyang Tian, Jingyuan Li, Hui Song

“…The mRNA and protein expression levels of these cytokines were also analyzed in HGFs transiently transfected with HO-1 small interfering RNA (siRNA) in response to TNF-α and IL-1β stimulation. …”
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Interleukin-1 Receptor-Associated Kinase-3 Aggravates Neuroinflammatory Injury After Intracerebral Hemorrhage via Activation NF-&kappa;B/IL-17A Pathway in Mice by Wang J, Li Y, Tan C, Shao J, Tang W, Kong Q, Sheng W, Ding Z, Li F, Piao J, Lv D, Hu L, Wang Q, Jiang X

“…RNA-seq was performed to explore the mechanism by which IRAK3 promotes inflammation after ICH. …”
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Transcriptomic profiling of lncRNAs and mRNAs in a venous thrombosis mouse model by Risheng Hao, Haobo Li, Xincheng Li, Jixiang Liu, Xiaofan Ji, Hong Zhang, Zhu Zhang, Peiran Yang, Zhenguo Zhai

“…Enrichment analyses revealed significant pathways, including HIF-1α signaling, glycolysis/gluconeogenesis, and platelet activation. A lncRNA-miRNA-mRNA network highlighted key regulatory interactions. …”
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Ultrasound‐Activated Precise Sono‐Immunotherapy for Breast Cancer with Reduced Pulmonary Fibrosis by Xiang Li, Gao He, Hui Jin, Xinyu Xiang, Dong Li, Renmiao Peng, Jing Tao, Xinping Li, Kaiyang Wang, Yu Luo, Xiaoan Liu

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β-Catenin mediated TAM phenotype promotes pancreatic cancer metastasis via the OSM/STAT3/LOXL2 axis by Yijia Zhang, Xinya Zhu, Liyuan Chen, Tianyu Gao, Guang Chen, Jin Zhu, Guoyu Wang, Daiying Zuo

“…However, the molecular mechanisms by which tumor-associated macrophages (TAMs) promote PDAC progression, particularly the role of β-catenin signaling in regulating TAM phenotype and function, remain incompletely understood.Initially, we performed comprehensive analyses of RNA-seq and single-cell RNA-seq (scRNA-seq) datasets to investigate OSM and LOXL2 expression patterns in PDAC. …”
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Genetic Polymorphism and Expression of CXCR4 in Breast Cancer by Marina Okuyama Kishima, Karen Brajão de Oliveira, Carolina Batista Ariza, Carlos Eduardo Coral de Oliveira, Roberta Losi Guembarovski, Bruna Karina Banin Hirata, Felipe Campos de Almeida, Glauco Akelinghton Freire Vitiello, Kleber Paiva Trugilo, Alda Fiorina Maria Losi Guembarovski, Walter Jorge Sobrinho, Clodoaldo Zago Campos, Maria Angelica Ehara Watanabe

“…The present study aimed to investigate the influence of CXCR4 rs2228014 polymorphism on its mRNA and protein expression in breast cancer samples. …”
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