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1521
Biosynthetic pathway for leukotrienes is stimulated by lipopolysaccharide and cytokines in pig endometrial stromal cells
Published 2025-01-01“…LPS increased LTAH mRNA abundance, while TNF-α, IL-1β and IL-10 augmented LTAH mRNA and protein abundances. …”
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1522
Palmitoylation-related gene ZDHHC22 as a potential diagnostic and immunomodulatory target in Alzheimer’s disease: insights from machine learning analyses and WGCNA
Published 2025-01-01“…In addition, 25 miRNAs and 55 lncRNAs were predicted to potentially target ZDHHC22, forming the basis for a lncRNA–miRNA–mRNA ceRNA network. Conclusions This study is the first to use bioinformatics methods to identify ZDHHC22 as a key KPRG in AD, highlighting its potential role in disease diagnosis and immune regulation. …”
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1523
A single-cell atlas of the Culex tarsalis midgut during West Nile virus infection.
Published 2025-01-01“…However, there were higher levels of WNV RNA (vRNA) in enteroendocrine cells (EE), suggesting enhanced replication in this population. …”
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1524
A Proinflammatory Effect of the β-Glucan from Pleurotus cornucopiae Mushroom on Macrophage Action
Published 2017-01-01“…However, the PCPS did not induce to express both IL-12 and IL-10 mRNA in the macrophages. Next, the P. cornucopiae extract (containing mainly PCPS) treatment against mice showed significant increases in TNF and IL-1β mRNA expressions in the peritoneal macrophages of them. …”
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1525
Computed Energetics of Nucleotides in Spatial Ribozyme Structures: An Accurate Identification of Functional Regions from Structure
Published 2004-01-01“…Ribozymes are functionally diverse RNA molecules with intrinsic catalytic activity. …”
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1526
The population growth and the nutritional status of Moina macrocopa feed with rice bran and cassava bran suspensions
Published 2017-07-01“…This study also found that Moina culture with rice bran suspension has higher total value of RNA, total value of DNA, the ratio RNA/ DNA, FCR, and concentration of protein and amino acid than Moina culture with cassava bran suspension. …”
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1527
Dendrimer functionalized folate-targeted gold nanoparticles for luciferase gene silencing in vitro: A proof of principle study
Published 2019-03-01“…Use of exogenous small interfering RNA (siRNA) has shown potential in gene silencing. …”
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1528
Comparison of saliva and blood derived cell free RNAs for detecting oral squamous cell carcinoma
Published 2025-02-01“…In our study to enhance OSCC detection, we analyzed cell-free RNA (cfRNA) transcriptomes (mRNA, lncRNA) from blood (plasma) and saliva samples of individuals in three groups: OSCC group, oral benign tumor group, and a normal control group. …”
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1529
Exploration of Some Nutrient Absorption–Related Genes and Intestinal Histology in Japanese Quails (Coturnix japonica) Throughout Their Productive Lifespan
Published 2024-11-01“…The mRNA abundance of the CALB1, SGLT1, SGLT5, EAAT3 and NaPi‐IIb genes were compared among groups. …”
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1530
Comprehensive Analysis and Functional Characteristics of Differential Expression of N6-Methyladenosine Methylation Modification in the Whole Transcriptome of Rheumatoid Arthritis
Published 2022-01-01“…N6-methyladenosine (m6A) modification is the most prevalent chemical modification in eukaryotic mRNA and is associated with the development of various immune diseases. …”
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1531
Staphylococcus aureus blocks host autophagy through circSyk/miR-5106/Sik3 axis to promote progression of bone infection.
Published 2025-01-01“…In this study, we demonstrate that a circular RNA (circRNA), circSyk, is a potential biological target for the treatment of S. aureus-induced bone infection. …”
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1532
Complete Mitochondrial Genome of <i>Niphon spinosus</i> (Perciformes: Niphonidae): Genome Characterization and Phylogenetic Analysis
Published 2025-01-01“…The H-strand encoded 28 genes (14 tRNA, 2 rRNA, and 12 PCGs), and D-loop, whereas the L-strand encoded the remaining 9 genes (8 tRNA and <i>ND6</i>). …”
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1533
Forskolin Inhibits Lipopolysaccharide-Induced Modulation of MCP-1 and GPR120 in 3T3-L1 Adipocytes through an Inhibition of NFκB
Published 2016-01-01“…In DC, LPS increased MCP-1, TLR-4, and nuclear factor-κB1 (NFκB1) mRNA levels, whereas it decreased GPR120 mRNA levels. …”
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1534
ERK5 Contributes to VEGF Alteration in Diabetic Retinopathy
Published 2010-01-01“…On the other hand, constitutively active MEK5, an activator of ERK5, increased ERK5 activation and ERK5 and KLF2 mRNA expression and attenuated basal- and glucose-induced VEGF mRNA expression. …”
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1535
Computational analysis of spliced leader trans-splicing in the regenerative flatworm <i>Macrostomum lignano</i> reveals its prevalence in conserved and stem cell related genes
Published 2021-03-01“…In eukaryotes, trans-splicing is a process of nuclear pre-mRNA maturation where two different RNA molecules are joined together by the spliceosomal machinery utilizing mechanisms similar to cis-splicing. …”
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1536
Exploring Heat-Response Mechanisms of MicroRNAs Based on Microarray Data of Rice Post-meiosis Panicle
Published 2020-01-01“…By integrating paired differentially expressed (DE) miRNAs and mRNA expression profiles, we found that the expression levels of 29 DE-miRNA families were negatively correlated to their 178 DE-target genes. …”
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1537
3-Acetyldeoxynivalenol induces pyroptosis in leydig cells via METTL3-mediated N6-methyladenosine modification of NLRP3
Published 2025-01-01“…RNA immunoprecipitation (RIP) assays further demonstrated that IGF2BP1 selectively recognizes m6A-modified NLRP3 mRNA, contributing to its stabilization. …”
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1538
Mechanism of Repeat-Associated MicroRNAs in Fragile X Syndrome
Published 2012-01-01“…After transcription, the trinucleotide repeats can fold into RNA hairpins and are further processed by Dicer endoribonuclases to form microRNA (miRNA)-like molecules that are capable of triggering targeted gene-silencing effects in the TREDs. …”
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1539
Prenatal maternal stress in rats alters the epigenetic and transcriptomic landscape of the maternal-fetal interface across four generations
Published 2025-01-01“…The transgenerational persistence of critical DNAm, miRNA and mRNA signatures may explain familial non-genetic disease risks.…”
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1540
CRP and TNF-α Induce PAPP-A Expression in Human Peripheral Blood Mononuclear Cells
Published 2012-01-01“…Actinomycin D treatment completely prevented CRP and TNF-α induction of PAPP-A mRNA and protein expression. Additionally, nuclear factor- (NF-) κB inhibitor (BAY11-7082) potently inhibited both CRP and TNF-α stimulated PAPP-A mRNA and protein expression. …”
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