Commercially Supplied Amine-Modified siRNAs May Require Ultrafiltration prior to Conjugation with Amine-Reactive Compounds by Shannen Lau, Bim Graham, Ben J. Boyd, Colin W. Pouton, Paul J. White

“…Conjugation of siRNA to macromolecules such as serum albumin has multiple potential benefits, including enhanced extravasation via albumin-mediated transcytosis across endothelial cells and reduced renal clearance. …”
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Diagnostic Test to Identify Parkinson’s Disease from the Blood Sera of Chinese Population: A Cross-Sectional Study by Guangan Tong, Pingping Zhang, Wenbin Hu, Kun Zhang, Xianwen Chen

“…The expression of potential microRNA (miRNA) candidates isolated from serum and cerebrospinal fluid (CSF) exosomes of PD patients was assessed for their diagnostic value and their potential role as biomarkers for PD was explored. …”
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Role of Eukaryotic Initiation Factors during Cellular Stress and Cancer Progression by Divya Khandige Sharma, Kamiko Bressler, Harshil Patel, Nirujah Balasingam, Nehal Thakor

“…Protein synthesis can be segmented into distinct phases comprising mRNA translation initiation, elongation, and termination. …”
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circCOL1A1 Promotes the Progression of Gastric Cancer Cells through Sponging miR-145 to Enhance RABL3 Expression by Yue Ma, Yanyi Ren, Huitao Wen, Chengcheng Cui

“…Circular RNA has been reported to be a new noncoding RNA which plays important roles in tumor progression. …”
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Identification of Potential lncRNAs and miRNAs as Diagnostic Biomarkers for Papillary Thyroid Carcinoma Based on Machine Learning by Fei Yang, Jie Zhang, Baokun Li, Zhijun Zhao, Yan Liu, Zhen Zhao, Shanghua Jing, Guiying Wang

“…The regulatory network between optimal diagnostic lncRNA and mRNAs and optimal diagnostic miRNA and mRNAs was identified, followed by the construction of ceRNA network of lncRNA-mRNA-miRNA. …”
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Induction of annexin-1 at transcriptional and post-transcriptional level in rat brain by methylprednisolone and the 21-aminosteroid U74389F by P. H. Voermans, K. G. Go, G. J. Ter Horst, M. H. J. Ruiters, E. Solito, L. Parente

“…Brain tissue of rats pretreated with methylprednisolone or with the 21-aminosteroid U74389F, and that of untreated control rats, was assessed for the expression of annexin-1 (Anx-1) and the transcription of its mRNA. For this purpose Anx-1 cDNA was amplified and simultaneously a T7-RNA-polymerase promoter was incorporated into the cDNA using a polymerase chain reaction (PCR). …”
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Graphene Oxide-Gold Star Construct on Triangular Electrodes for Alzheimer’s Disease Identification by Wenlong Chang, Jing Zhao, Lu Liu, Xiaoming Xing, Chao Zhang, Huihong Meng, Subash C. B. Gopinath, Yonggang Liu

“…Further control sequences of miRNA-21 and single and triple base mismatched miRNA-137 did not show a significant response in current changes, indicating the specific miRNA-137 detection for diagnosing AD.…”
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Challenges in HIV Diagnosis Algorithm: Experience of the Confirmation Laboratory by Özgür Appak, Derya Özarslan, Arzu Nazlı, Ayca Arzu Sayiner

“…In the algorithm, the number of Geenius tests would have been reduced by 25% if HIV-1-RNA had been applied as a reflex test to HIV-Ag/Ab positive samples and Geenius testing had been performed on RNA negative samples. …”
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Prediction of Associations between OMIM Diseases and MicroRNAs by Random Walk on OMIM Disease Similarity Network by Hailin Chen, Zuping Zhang

“…However, efforts made to uncover OMIM disease-miRNA associations are lacking and the majority of diseases in the OMIM database are not associated with any miRNA. …”
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Structural Determinants of Photoreactivity of Triplex Forming Oligonucleotides Conjugated to Psoralens by Rajagopal Krishnan, Dennis H. Oh

“…Triplex-forming oligonucleotides (TFOs) with both DNA and 2′-O-methyl RNA backbones can direct psoralen photoadducts to specific DNA sequences. …”
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Taxonomic and Characterization Methods of Streptomyces: A Review by Jodi Woan-Fei Law, Kei-Xian Tan, Sunny Hei Wong, Nurul-Syakima Ab Mutalib, Learn-Han Lee

“… The 16S ribosomal RNA gene is the gold standard for taxonomic identification and phylogenetic study of most of the bacteria. …”
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THE CHARACTERISTICS OF MIRNA BINDING SITES IN MRNA OF ZFHX3 GENE AND ITS ORTHOLOGS by A. М. Kondybayeva, A. N. Akimniyazova, S. U. Kamenova, A. Т. Ivashchenko

“…The characteristics of miRNA–mRNA interaction were determined using MirTarget software. …”
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Diagnosis of hepatocellular carcinoma using liquid biopsy-based biomarkers: a systematic review and network meta-analysis by Yutong Jiang, Yutong Jiang, Shangwen Qi, Shangwen Qi, Rongrong Zhang, Rongrong Zhang, Ruixia Zhao, Yu Fu, Yuxuan Fang, Yuxuan Fang, Mingyi Shao

“…Subsequent analysis of circRNA and mRNA highlighted hsa_circ_000224, hsa_circ_0003998, KIAA0101 mRNA and GPC-3mRNA as the optimal diagnostic biomarkers for distinguishing HCC from healthy populations and liver disease patients, respectively. …”
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Vaccination ARN messager (ARNm), modèle de transition de la biologie fondamentale à la médecine by Sansonetti, Philippe J.

“…Sixty years elapsed between the discovery of messenger RNA (mRNA) and the use of this molecule in an unprecedented global vaccination campaign that brought the Covid-19 pandemic under control. …”
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Structural insights into dynamics of the BMV TLS aminoacylation by Wen Yang, Ran Yi, Jing Yao, Yongxiang Gao, Shanshan Li, Qingguo Gong, Kaiming Zhang

“…Abstract Brome Mosaic Virus (BMV) utilizes a tRNA-like structure (TLS) within its 3’ untranslated region to mimic host tRNA functions, aiding aminoacylation and viral replication. …”
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Spatiotemporal control of translation in live zebrafish embryos via photoprotected mRNAs by Florian P. Weissenboeck, Melissa Pieper, Helena Schepers, Sophie Hötte, Nils Klöcker, Sabine Hüwel, Andreas van Impel, Stefan Schulte-Merker, Andrea Rentmeister

“…Several mechanisms acting on the mRNA level regulate when and where an mRNA is expressed. …”
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Functional Analysis of Genes Encoding Juvenile Hormone Receptor <i>Met</i> and Transcription Factor <i>Kr-h1</i> in the Reproductive Capacity of <i>Coccinella septempunctata</i> Ma... by Ying Cheng, Yuhang Zhou, Cao Li

“…There were no significant differences in the testes sizes of male ladybugs injected with <i>Met</i>-dsRNA when compared to <i>GFP</i>-dsRNA; however, the testis volume of ladybugs injected with <i>Kr-h1</i>-dsRNA was smaller than those injected with <i>GFP</i>-dsRNA. …”
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Long Noncoding RNAs-Related Diseases, Cancers, and Drugs by Jen-Yang Tang, Jin-Ching Lee, Yung-Ting Chang, Ming-Feng Hou, Hurng-Wern Huang, Chih-Chuang Liaw, Hsueh-Wei Chang

“…Long noncoding RNA (lncRNA) function is described in terms of related gene expressions, diseases, and cancers as well as their polymorphisms. …”
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Topological Characterization of Human and Mouse m5C Epitranscriptome Revealed by Bisulfite Sequencing by Zhen Wei, Subbarayalu Panneerdoss, Santosh Timilsina, Jingting Zhu, Tabrez A. Mohammad, Zhi-Liang Lu, João Pedro de Magalhães, Yidong Chen, Rong Rong, Yufei Huang, Manjeet K. Rao, Jia Meng

“…Further analysis reveals that RNA m5C methylation level is positively correlated with both RNA expression and RNA half-life. …”
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Comparative and phylogenetic analyses of the chloroplast genomes of mangrove plants by Jigui Yuan, Wei Gu, Haijie Yang, Mei Wang

“…The complete chloroplast genome of this species was 161,764 bp in length and comprised 84 protein-coding genes, eight rRNA (ribosomal RNA) genes, 37 tRNA (transfer RNA) genes. …”
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