Evaluation of Neutralizing Capacity of Tixagevimab plus Cilgavimab (AZD7442) against Different SARS-CoV-2 Variants: A Case Report Study with Comparison to a Vaccinated Population by Constant Gillot, Jean-Louis Bayart, Vincent Maloteau, Jean-Michel Dogné, Jonathan Douxfils, Julien Favresse

“…A cohort of subjects (n = 45) who had received the BNT162b2 mRNA COVID-19 vaccine has been included to compare these two preventive strategies. …”
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Complete Genome Sequence Analysis of Bacillus subtilis MC4-2 Strain That against Tobacco Black Shank Disease by Chunlan Shi, Shuquan Zeng, Xi Gao, Mehboob Hussain, Mingchuan He, Xurong Niu, Congcong Wei, Rui Yang, Mingxian Lan, Yonghui Xie, Zhijiang Wang, Guoxing Wu, Ping Tang

“…The MC4-2 strain was found to have good broad-spectrum inhibition by plate stand-off test. Based on 16S rRNA and gyrB genes, ANI analysis, and other comparative genomics methods, it was determined that the MC4-2 strain was Bacillus subtilis. …”
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In silico characterisation of the avocado WAK/WAKL gene family with a focus on genes involved in defence against Phytophthora cinnamomi by Aaron Harvey, Aaron Harvey, Noëlani van den Berg, Noëlani van den Berg, Velushka Swart, Velushka Swart

“…In this study, previously generated RNA-sequencing data were used to associate genes with the defence response, followed by promoter- and phylogenetic analysis of these genes/proteins. …”
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The Inhibitory Effects of Alpha 1 Antitrypsin on Endosomal TLR Signaling Pathways by Ahmed S. Elshikha, Georges Abboud, Rigena Avdiaj, Laurence Morel, Sihong Song

“…The proteolytic processing of these receptors in the endolysosome is required for signaling in response to DNA and single-stranded RNA, respectively. Targeting this proteolytic processing may represent a novel strategy to inhibit TLR-mediated pathogenesis. …”
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An integrated strategy for sequential nitrite removal and methane recovery: Sludge fermentation driven by nitrite reduction by Xiaodi Li, Mengxue Sun, Bo Wang, Wei Zeng, Yongzhen Peng

“…Model-based analysis indicated that nitrite reduction enhanced the maximum methane yield and methane production rate, aligning with the aforementioned analysis. 16S rRNA analysis unraveled that the bacterial abundance associated with hydrolysis increased. …”
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Deficiency of Dietary Fiber in Slc5a8-Null Mice Promotes Bacterial Dysbiosis and Alters Colonic Epithelial Transcriptome towards Proinflammatory Milieu by Sathish Sivaprakasam, Pramodh K. Ganapathy, Mohd Omar Faruk Sikder, Moamen Elmassry, Sabarish Ramachandran, Kameswara Rao Kottapalli, Vadivel Ganapathy

“…We fed WT and KO mice with fiber-containing diet (FC-diet) or fiber-free diet (FF-diet) and analyzed the luminal bacterial composition by sequencing 16S rRNA gene in feces. Interestingly, results showed significant differences in the microbial community depending on dietary fiber content and on the presence or absence of Slc5a8. …”
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SENP-1和HIF-1α在肝细胞肝癌中的表达及临床意义 by 李湘竑, 杨定华, 钟克波, 毕民平, 李光辉, 廖晓明

“…【结果】 肝癌组织与癌边缘组织SENP-1、HIF-1αmRNA表达显著高于非癌组织,SENP-1和HIF-1α在癌边缘组织及癌组织细胞的胞浆内有明显表达,癌边缘组织的表达强度及阳性率显著高于癌组织( P < 0. 05),且表达阳性率随肝癌组织分化程度降低而增高,而在非癌组织的实质细胞中则不表达;在癌边缘组织及癌组织中SENP-1与HIF-1α蛋白表达正相关(r = 0.761,P = 0.000;r = 0.346,P = 0.008),HIF-1α蛋白表达与MVD负相关(r = -0.684,P = 0.000;r = -0.808,P = 0.000).…”
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Nanoplastics induces arrhythmia in human stem-cells derived cardiomyocytes by Shirley Pei Shan Chia, Jeremy Kah Sheng Pang, Winanto Winanto, Boon-Seng Soh

“…Complementing these in vitro findings, transcriptome profiling of mice exposed to NPs for 8 weeks revealed disrupted RNA splicing, dysregulated protein translation, and defective protein folding. …”
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RETRACTED ARTICLE: Establishment of an Acanthamoeba keratitis mouse model confirmed by amoebic DNA amplification by Heekyoung Kang, Hae-Jin Sohn, A-Young Park, A-Jeong Ham, Jeong-Heon Lee, Young-Hwan Oh, Yong-Joon Chwae, Kyongmin Kim, Sun Park, Hongseok Yang, Suk-Yul Jung, Jong-Hyun Kim, Ho-Joon Shin

“…The AK signs were grossly observed and PCR was performed using P-FLA primers to amplify the Acanthamoeba 18S-rRNA gene from mouse ocular tissue. The experimental AK mouse model was characterized by typical hazy blurring and melting of the mouse cornea established on day 1 post-inoculation. …”
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New insights into the stipitate hydnoid fungi Sarcodon, Hydnellum, and the formerly informally defined Neosarcodon, with emphasis on the edible species marketed in Southwest China by Di Wang, Hui Feng, Jie Zhou, Tian-Hai Liu, Zhi-Yuan Zhang, Ying-Yin Xu, Jie Tang, Wei-Hong Peng, Xiao-Lan He

“…Phylogeny of the traditional Sarcodon s. lat. and Hydnellum s. lat. was reconstructed from the combined internal transcribed spacer (ITS), nuclear large ribosomal subunit (nLSU) and RNA polymerase II second largest subunit (RPB2) dataset based on expanded samples to reevaluate the taxonomic placements of the two genera. …”
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Characterization of H460R, a Radioresistant Human Lung Cancer Cell Line, and Involvement of Syntrophin Beta 2 (SNTB2) in Radioresistance by Chang-Nim Im, Byeong Mo Kim, Eun-Yi Moon, Da-Won Hong, Joung Whan Park, Sung Hee Hong

“…Knockdown of SNTB2 by siRNA was more sensitive than the control after IR exposure in H460, H460R, and H1299 cells. …”
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X-linked ubiquitin-specific peptidase 11 (USP11) increases susceptibility to Cushing’s disease in women by Tao Zhang, Yanting Liu, Fang Liu, Kaiyu Guo, Runhua Tang, Jingwei Ye, Li Xue, Zhipeng Su, Zhe Bao Wu

“…In this study, we analyzed the expression of deubiquitinating enzymes in functioning ACTH PitNETs from both male and female subjects using RNA sequencing and identified USP11 as a potential susceptibility factor contributing to the higher prevalence of these PitNETs in females. …”
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Early transcriptomic changes at the skin interface during Powassan virus transmission by Ixodes scapularis ticks by Dakota N. Paine, Dakota N. Paine, Meghan Hermance, Saravanan Thangamani, Saravanan Thangamani, Saravanan Thangamani

“…In this study, we investigated the global cutaneous transcriptomic changes associated with tick bites during POWV transmission.MethodsWe collected skin biopsies from the tick attachment sites at 1, 3, and 6 h after feeding by POWV-infected and uninfected ticks, followed by RNA sequencing of these samples. Differentially expressed genes were analyzed for pathway enrichment using gene ontology and pathway enrichment analyses.ResultsOur findings reveal that tick feeding alone significantly impacts the skin transcriptome within the first 1 to 3 h of tick attachment. …”
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Manure application increases soil doxycycline and zinc levels and resistance gene abundance by Jian Zhao, Jiangjie He, Yurou Han, Junwei Liang, Yucheng Chen, Yimo Zhang, Jizhen Liu, Qizhong Huang, Weihong Xu

“…Through an 8-year field experiment coupled with 16S rRNA sequence analysis, we explored the dynamics of DOX and Zn contamination and their influence on soil microbial diversity and resistance gene expression. …”
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Effect of a single rectal fecal microbiota transplantation on clinical severity and fecal microbial communities in dogs with chronic inflammatory enteropathy by Jorge Pérez‐Accino, Mazdak Salavati, Laura Glendinning, Silke Salavati Schmitz

“…Sequencing of microbiota (16S rRNA, Illumina) was performed and compared by accepted analysis pipelines. …”
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All-Trans Retinoic Acid Improves the Effects of Bone Marrow-Derived Mesenchymal Stem Cells on the Treatment of Ankylosing Spondylitis: An In Vitro Study by Deng Li, Peng Wang, Yuxi Li, Zhongyu Xie, Le Wang, Hongjun Su, Wen Deng, Yanfeng Wu, Huiyong Shen

“…The secretion and the mRNA level of key cytokines were measured with cytometric bead array and quantitative real-time PCR, respectively. …”
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Applications of cell penetrating peptide-based drug delivery system in immunotherapy by Jing-Jing Du, Ru-Yan Zhang, Shangchi Jiang, Shanshan Xiao, Yiting Liu, Yongheng Niu, Wen-Xiang Zhao, Dongyuan Wang, Dongyuan Wang, XianShi Ma

“…These properties have made them as efficient drug-delivery tools to deliver therapeutic molecules to cells and tissues in a nontoxic manner, including small molecules, DNA, siRNA, therapeutic proteins and other various nanoparticles. …”
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Akkermansia muciniphila Mediated the Preventive Effect of Disulfiram on Acute Liver Injury via PI3K/Akt Pathway by Ruonan Zhang, Xuewei Sun, Han Lu, Xinrui Zhang, Mingyan Zhang, Xuewen Ji, Xinyi Yu, Chengliang Tang, Zihan Wu, Yinghua Mao, Jin Zhu, Minjun Ji, Zhan Yang

“…We utilised bacterial 16S rRNA gene profiling, antimicrobial treatments, and faecal microbiota transplantation tests to explore whether DSF therapy for ALI is dependent on gut microbiota. …”
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Comparison of Rapidly Proliferating, Multipotent Aortic Valve-Derived Stromal Cells and Valve Interstitial Cells in the Human Aortic Valve by Yuming Huang, Kang Xu, Tingwen Zhou, Peng Zhu, Nianguo Dong, Jiawei Shi

“…In addition, the stem cell markers CD163, CD133, and CD106 were all expressed in VDSCs. RNA-sequencing identified 1595 differentially expressed genes between VDSCs and VICs of which 301 were upregulated and 1294 were downregulated. …”
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Resistance-breaking strains of tomato spotted wilt virus hamper photosynthesis and protein synthesis pathways in a virus accumulation-dependent manner in Sw5-carrying tomatoes by Maria Isabella Prigigallo, Ugo Picciotti, Giovanni Bubici

“…Transcriptome sequencing (RNA-Seq) was used to analyze 18 tomato leaf samples collected from a field crop naturally infected by SRB TSWV in Italy. …”
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