-
3561
Gene Identification and Characterization of Correlations for DEPs_DEGs Same Trend Responding to Salinity Adaptation in Scylla paramamosain
Published 2019-01-01“…This study performed a correlation analysis of RNA sequencing transcriptomics and iTRAQ proteomics in order to investigate the adaptation mechanisms to sudden salinity drop from 23‰ to 3‰. …”
Get full text
Article -
3562
ET-1 Promotes Differentiation of Periodontal Ligament Stem Cells into Osteoblasts through ETR, MAPK, and Wnt/β-Catenin Signaling Pathways under Inflammatory Microenvironment
Published 2016-01-01“…TNF-α, IL-1β, and IL-6 levels were evaluated by ELISA and western blot. Runx2, OCN, and COL1 mRNA and western levels were detected by RT-PCR and western blot, respectively. …”
Get full text
Article -
3563
Use of a Sendai virus-based vector for effcient transduction of pinniped fbroblasts
Published 2019-01-01“…There are several ways to deliver reprogramming transcription factors: RNA, proteins, plasmids, viral vectors etc. The most effective delivery systems for mouse and human cells are based on viral vectors. …”
Get full text
Article -
3564
Studies on the reduction of organic load from palm oil mill effluent (POME) by bacterial strains
Published 2024-02-01“…Results Sequencing of the 16S rRNA of the isolates suggests that they were identified as Micrococcus luteus 101 PB, Stenotrophomonas maltophilia 102 PB, Bacillus cereus 103 PB, Providencia vermicola 104 PB, Klebsiella pneumoniae 105 PB and Bacillus subtilis 106 PB. …”
Get full text
Article -
3565
Kırşehir İlinden Toplanan Morchella esculenta (L.) Pers (Kuzu Göbeği) Mantarlarının Moleküler Karakterizasyonu ve Antimikrobiyal Aktivitelerinin Belirlenmesi
Published 2021-03-01“…Bu çalışmada Kırşehir ili ve ilçelerinden toplanan Kuzu Göbeği mantarlarının 18S rRNA ve ITS gen bölgeleri çoğaltılarak moleküler olarak tanımlamaları gerçekleştirilmiştir. …”
Get full text
Article -
3566
Exosome-loading miR-205: a two-pronged approach to ocular neovascularization therapy
Published 2025-01-01“…Recent studies have highlighted the roles of noncoding RNAs in various biological processes, paving the way for RNA-based therapeutics. In this study, we report a marked down-regulation of miR-205 under pathological conditions. miR-205 potently inhibits endothelial cell functions critical for pathological neovascularization, including proliferation, migration, and tube formation. …”
Get full text
Article -
3567
Amylin: Localization, Effects on Cerebral Arteries and on Local Cerebral Blood Flow in the Cat
Published 2001-01-01“…With RT-PCR and Real-Time�PCR we revealed the presence of mRNA for calcitonin receptor-like receptor (CLRL) and receptor-activity-modifying proteins (RAMPs) in cat cerebral arteries. …”
Get full text
Article -
3568
The Efficacy and Mechanism of Chinese Herbal Medicine on Diabetic Kidney Disease
Published 2019-01-01“…In terms of experimental research, studies provided evidence for the efficacy of CHM from the perspectives of balancing metabolic disorders, reducing inflammatory response and oxidative stress, antifibrosis, protecting renal innate cells, and regulating microRNA and metabolism. CHM consisting of different ingredients may play a role in synergistic interactions and multiple target points in the treatment of DKD.…”
Get full text
Article -
3569
Modulatory Action by the Serotonergic System: Behavior and Neurophysiology in Drosophila melanogaster
Published 2016-01-01“…The effects of feeding fluoxetine, a selective serotonin reuptake inhibitor, during early second instars were also examined. 5-HT receptor subtypes were manipulated using RNA interference mediated knockdown and 5-HT receptor insertional mutations. …”
Get full text
Article -
3570
A daily rhythm of cell proliferation in a songbird brain
Published 2025-02-01“…We injected the birds with the cell proliferation marker 5-ethynyl-2´-deoxyuridine (EdU; thymidine analog), quantified the number of dividing cells in the neurogenic ventricular zone (VZ), and measured mRNA expression of clock genes as well as genes indicating cell proliferation or apoptosis. …”
Get full text
Article -
3571
Targets and Candidate Agents for Type 2 Diabetes Treatment with Computational Bioinformatics Approach
Published 2014-01-01“…The dysfunctional pathways, the potential transcription factor, and microRNA targets were analyzed by bioinformatics methods. …”
Get full text
Article -
3572
Inhibitory Substances Produced by Native Lactobacillus plantarum UTNCys5-4 Control Microbial Population Growth in Meat
Published 2019-01-01“…The Cys5-4 peptides exerted their bacteriolytic mode of action inducing damage in the cell membrane of the target bacteria, allowing the leaching of DNA/RNA content. The results indicate that coating meat with CFS containing Cys5-4 is a promising approach to protect against further contamination by microorganism spoilage, as well as an alternative for increasing the shelf life of raw meat.…”
Get full text
Article -
3573
The Japanese encephalitis virus NS1' protein facilitates virus infection in mosquitoes.
Published 2025-01-01“…Additionally, this research elucidated the underlying mechanism by which the NS1' protein enhances viral infection in mosquitoes by RNA-Seq analysis. Specifically, the NS1' protein was found to facilitate infection through the suppression of antimicrobial peptides (AMPs) regulated by the Toll pathway.…”
Get full text
Article -
3574
Myeloma cell-derived CXCL7 facilitates proliferation of tumor cells and occurrence of osteolytic lesions through JAK/STAT3 pathway
Published 2025-02-01“…By analyzing transcriptome data and single-cell RNA-seq data from our center and the GEO database, a subset of MM cells with high expression levels of chemokine CXCL7 was identified. …”
Get full text
Article -
3575
A Comparative Study on Growth Performance, Body Composition, and Liver Tissue Metabolism Rearing on Soybean Lecithin-Enriched Artemia Nauplii and Microdiet in Rock Bream (Oplegnath...
Published 2023-01-01“…Larvae fed a MD showed decreased lipolysis-related lipase activity as well as decreased amino acid catabolism-related alanine aminotransferase and aspartate aminotransferase enzyme activities in liver tissue. RNA sequencing revealed that feeding with the MD primarily increased the expression of lipogenesis-related genes and protein translation-related gene expression in the liver tissue. …”
Get full text
Article -
3576
Epidemiology of Liver Cancer in Europe
Published 2000-01-01“…New laboratory techniques and biological markers such as polymerase chain reaction detection of HBV DNA and HCV RNA, as well as specific mutations related to LC, may help to provide quantitative estimates of the risk related to each these factors.…”
Get full text
Article -
3577
A Survey of Wild Indigenous <i>Cryptostylis ovata</i> Orchid Populations in Western Australia Reveals Spillover of Exotic Viruses
Published 2025-01-01“…Eighty-three <i>C. ovata</i> samples from 16 populations were collected, and sequencing was used to identify RNA viruses from them. In one population, all tested plants were co-infected with isolates of the exotic-to-Australia viruses Ornithogalum mosaic virus (OrMV) and bean yellow mosaic virus (BYMV). …”
Get full text
Article -
3578
Differential Impacts of Soybean and Fish Oils on Hepatocyte Lipid Droplet Accumulation and Endoplasmic Reticulum Stress in Primary Rabbit Hepatocytes
Published 2016-01-01“…SOLE also significantly upregulated glucose-regulated protein 94 mRNA and protein expression. These data indicate that SOLE, but not FOLE, damage the ER and mitochondria, resulting in lipid droplets accumulation and ER stress and, finally, hepatocyte injury. …”
Get full text
Article -
3579
Preliminary screening of new biomarkers for sepsis using bioinformatics and experimental validation.
Published 2025-01-01“…<h4>Results</h4>Differential analysis yielded a total of 5125 mRNA. WGCNA identified 5 modules and screened 3 core genes (S100A11, QPCT, and IFITM2). …”
Get full text
Article -
3580
Characterization of Malignant Melanoma Using Vibrational Spectroscopy
Published 2005-01-01“…The comparative analysis of various parameters calculated from the spectral data of the normal epidermis and the abnormal regions showed that the changes in the nucleic acids was a significant indicator of the abnormal nature of the tissues. The RNA/DNA ratio was decreased in case of both melanoma and nevus compared to the epidermis. …”
Get full text
Article