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3421
Molecular investigation of how drought stress affects chlorophyll metabolism and photosynthesis in leaves of C3 and C4 plant species: A transcriptome meta-analysis
Published 2025-02-01“…In this study, we analyzed RNA-seq data from leaves of common wheat (Triticum aestivum) and sorghum (Sorghum bicolor), as representatives of C3 and C4, using a meta-analysis approach to investigate the photosynthesis-related genes involved in the response to drought stress. …”
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3422
Human epididymis protein 4-annexin II binding promotes aberrant epithelial-fibroblast crosstalk in pulmonary fibrosis
Published 2025-01-01“…Finally, intratracheal administration of HE4 shRNA lentivirus protects mice against BLM-induced PF. …”
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3423
Phylogeny of Flavobacteria Group Isolated from Freshwater Using Multilocus Sequencing Analysis
Published 2013-12-01“…Sequence analysis of the 16S rRNA gene has been widely used for the classification of microorganisms. …”
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3424
Differential Expression of Matrix Metalloproteases in Human Fibroblasts with Different Origins
Published 2012-01-01“…Interestingly, we found major differences in basal mRNA expression especially for MMP1 and MMP3. Moreover, we treated fibroblasts with TNF-α and observed different alterations under these proinflammatory conditions. …”
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3425
Preliminary results of open comparative randomized study PHG-M3/P01-09 «ORION» on application of «Phosphogliv» in combined therapy of chronic hepatitis C
Published 2011-06-01“…Analysis of cases with rapid virologic response (absence of HCV RNA or its level less than 750 copies/ml) within 4 wks of treatment has shown, that only the group phosphogliv/standard interferon α-2b/ribavirin included 3 such cases and that was especially important – all had the 1-st virus genotype. …”
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3426
The Protective Effect of Lidocaine on Septic Rats via the Inhibition of High Mobility Group Box 1 Expression and NF-κB Activation
Published 2013-01-01“…The mechanism was relative to the inhibitory effect of lidocaine on the mRNA expression level of HMGB1 in multiple organs, release of HMGB1 to plasma, and activation of NF-κB.…”
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3427
Changes in Metabolic Regulation and the Microbiota Composition after Supplementation with Different Fatty Acids in db/db Mice
Published 2022-01-01“…The lipid, hormonal profiles, and composition of the culture-dependent microbiota and the phylogenetic analysis based on the 16S rRNA gene sequencing were determined for identification of the intestinal microbiota. …”
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3428
Effect of symbiont-targeted control of Halyomorpha halys on the co-occurring pentatomid community
Published 2025-02-01“…Their symbionts were identified as allied to the genus Pantoea through 16S rRNA gene sequencing and also other bacteria were detected in the V4 ventricle of the midgut. …”
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3429
An Interactive Database of Cocaine-Responsive Gene Expression
Published 2002-01-01“…The database is limited to statistically significant changes in mRNA or protein expression after cocaine administration. …”
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3430
Colonization of a Central Venous Catheter by the Hyaline Fungus Fusarium solani Species Complex: A Case Report and SEM Imaging
Published 2013-01-01“…Gene amplification and direct sequencing of the fungal ITS1 rRNA region and the EF-1alpha gene confirmed the isolate as belonging to the Fusarium solani species complex. …”
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3431
Posttranscriptional Suppression of Lipopolysaccharide-Stimulated Inflammatory Responses by Macrophages in Middle-Aged Mice: A Possible Role for Eukaryotic Initiation Factor 2α
Published 2014-01-01“…Although LPS-stimulated secretion of tumor necrosis factor-α (TNF-α) by the macrophages from middle-aged mice was significantly lower than that from young mice, LPS caused marked increases in levels of TNF-α mRNA in macrophages from middle-aged as well as young mice. …”
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3432
Identification and Validation of a Potential Stemness-Associated Biomarker in Hepatocellular Carcinoma
Published 2022-01-01“…The data of HCC patients from The Cancer Genome Atlas (TCGA) were collected and divided based on the mRNA expression-based stemness index (mRNAsi) in this study. …”
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3433
Functionalized oligonucleotides, synthetic catalysts as enzyme mimics
Published 2024-04-01“…We will exemplify the development of FuON either presenting RNA-cleaving activity or acting as peroxidase or protease mimics and discuss the impact of the introduced modifications.…”
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3434
XRCC5 VNTR, XRCC6 -61C>G, and XRCC7 6721G>T Gene Polymorphisms Associated with Male Infertility Risk: Evidences from Case-Control and In Silico Studies
Published 2017-01-01“…The XRCC7 6721G>T gene polymorphism occurred in an acceptor-splicing site, but this polymorphism has no severe modification on XRCC7 mRNA splicing. Our results indicate the association of XRCC5 VNTR, XRCC6 -61C>G, and XRCC7 6721G>T gene polymorphisms with male infertility in Iranian men.…”
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3435
Therapeutic potential of SOX family transcription factors in osteoarthritis
Published 2025-12-01“…The regulation of the WNT signalling pathway, Nrf2/ARE signalling pathway, NF-κB signalling pathway and SOX9 is implicated in the emergence of osteoarthritis. Non-coding RNA may play a role in the onset and progression of osteoarthritis by modulating various SOX family members, including SOX2, SOX4, SOX5, SOX6, SOX8, SOX9 and SOX11.Conclusion SOX9 has the capability of mitigating the onset and progression of osteoarthritis through means such as medication therapy, stem cell therapy, recombinant adeno-associated virus (rAAV) vector therapy, physical therapy and other approaches.…”
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3436
Modern vaccines and coronavirus infections
Published 2020-12-01“…This review is on recent advances in the development of new generation vaccines, as well as those developed using earlier time-tested technologies: live attenuated vaccines, inactivated vaccines, recombinant vaccines, subunit vaccines, virus-like particle-based vaccines, synthetic peptide vaccines, DNA vaccines and mRNA vaccines. However, many infections are still not preventable with the currently available vaccines and they represent a major cause of mortality worldwide — for example, severe acute respiratory syndrome coronavirus, middle east respiratory syndrome coronavirus and severe acute respiratory syndrome coronavirus 2 that causes coronavirus disease 2019 — COVID-19. …”
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3437
Efficiency of pH-Sensitive Fusogenic Polymer-Modified Liposomes as a Vaccine Carrier
Published 2013-01-01“…In spleen lymphocytes from mice immunized with OVA-containing SucPG-modified liposomes, both IFN-γ-(Th1-type-) and IL-4-(Th2 type-) specific mRNA were detected. Moreover, substantial production of IFN-γ and IL-4 was demonstrated in spleen cells from OVA-containing SucPG-modified liposomes in vitro. …”
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3438
Identification of a Novel PPAR Signature for Predicting Prognosis, Immune Microenvironment, and Chemotherapy Response in Bladder Cancer
Published 2021-01-01“…The purpose of this study is to comprehensively investigate the function and prognostic value of PPAR-targeted genes in BLCA. Methods. The RNA sequencing data and clinical information of BLCA patients were acquired from The Cancer Genome Atlas (TCGA). …”
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3439
A Systematic Pan-Cancer Analysis of YY1 Aberrations and their Relationship with Clinical Outcome, Tumor Microenvironment, and Therapeutic Targets
Published 2022-01-01“…In addition, the functional mechanism of YY1 also involves viral carcinogenesis and ribonucleic acid (RNA) metabolism related functions. Our first pan-cancer analysis offers a pretty comprehensive knowledge of YY1’s oncogenic involvement in various cancers.…”
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3440
The Efficacy of On-Site Integration Screening and Microelimination Programs for Chronic Hepatitis C in a Detection Center: A Comparison of the Treatment Outcomes and Characteristic...
Published 2024-01-01“…The patients in the two groups did not differ significantly in terms of age, FIB-4 score, HCV RNA, HBV coinfection, hemogram findings, coagulation profiles, and renal function tests. …”
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