Annexin A2 Coordinates STAT3 to Regulate the Invasion and Migration of Colorectal Cancer Cells In Vitro by Dianhui Xiu, Lin Liu, Fengli Qiao, Haishan Yang, Lu Cui, Guifeng Liu

“…Results demonstrated that both Anxa 2 and STAT3 were highly expressed in CRC specimens in both mRNA and protein levels, with or without phosphorylation (Tyrosine 23 in Anxa 2 and Tyrosine 705 in STAT3). …”
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Identification and Evaluation of Strain B37 of Bacillus subtilis Antagonistic to Sapstain Fungi on Poplar Wood by XiaoHua Zhang, GuiHua Zhao, DeWei Li, ShunPeng Li, Qing Hong

“…The strain B37 was identified as Bacillus subtilis using sequences of the 16S rRNA gene, physiological biochemical, and morphological characteristics.…”
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Predicted Cold Shock Proteins from the Extremophilic Bacterium Deinococcus maricopensis and Related Deinococcus Species by Michael J. LaGier

“…Bacterial cold shock proteins (Csps) are a family of conserved, RNA chaperone proteins that commonly play a role in cold temperature adaptation, including a downward shift in temperature (i.e., cold shock). …”
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Disruption of the β-catenin destruction complex via Ephexin1-Axin1 interaction promotes colorectal cancer proliferation by Jeeho Kim, Young Jin Jeon, In-Youb Chang, Jung-Hee Lee, Ho Jin You

“…Through comprehensive analysis, including RNA sequencing data from TCGA and functional assays, we observed that Ephexin1 promotes tumor proliferation and migration by activating the Wnt/β-catenin pathway. …”
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Microbes, macrophages, and melanin: a unifying theory of disease as exemplified by cancer by Stacie Z. Berg, Jonathan Berg

“…However, it would fit well under the theory of evolution, if we were to look at it from the vantage point of pathogens and their supporting microbial communities colonizing humans and mutating host cells for their own benefit, as it does give them an evolutionary advantage and they are capable of selecting genes to mutate and of inserting their own DNA or RNA into hosts. In this article, we provide evidence that tumors are actually complex microbial communities composed of various microorganisms living within biofilms encapsulated by a hard matrix; that these microorganisms are what cause the genetic mutations seen in cancer and control angiogenesis; that these pathogens spread by hiding in tumor cells and M2 or M2-like macrophages and other phagocytic immune cells and traveling inside them to distant sites camouflaged by platelets, which they also reprogram, and prepare the distant site for metastasis; that risk factors for cancer are sources of energy that pathogens are able to utilize; and that, in accordance with our previous unifying theory of disease, pathogens utilize melanin for energy for building and sustaining tumors and metastasis. …”
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New members of Alternaria (Pleosporales, Pleosporaceae) collected from Apiaceae in Algeria by Nabahat Bessadat, Nelly Bataillé-Simoneau, Justine Colou, Bruno Hamon, Kihal Mabrouk, Philippe Simoneau

“…Phylogenetic analysis using sequences at four loci, the internal transcribed spacer of the rDNA region (ITS), glyceraldehyde-3-phosphate dehydrogenase (gpd), translation elongation factor 1-alpha (tef1), and RNA polymerase second largest subunit (rpb2), revealed that these isolates grouped into three sections, namely Embellisia, Embellisioides, and Eureka. …”
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Advancements in Antioxidant-Based Therapeutics for Spinal Cord Injury: A Critical Review of Strategies and Combination Approaches by Yang-Jin Shen, Yin-Cheng Huang, Yi-Chuan Cheng

“…This review provides a comprehensive and critical evaluation of recent advancements in antioxidant-based therapeutic strategies for SCI, including natural compounds, RNA-based therapies, stem cell interventions, and biomaterial applications. …”
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COVID-19: Understanding the New Variants of Concern by Ke-Yan Loo, Vengadesh Letchumanan

“…Fortunately, early evidence shows that the mRNA vaccines are still effective against the current circulating Omicron sublineages of the coronavirus. …”
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The Role of Methylation in Chronic Lymphocytic Leukemia and Its Prognostic and Therapeutic Impacts in the Disease: A Systematic Review by Sevastianos Chatzidavid, Christina-Nefeli Kontandreopoulou, Nefeli Giannakopoulou, Panagiotis T. Diamantopoulos, Christos Stafylidis, Marie-Christine Kyrtsonis, Maria Dimou, Panayiotis Panayiotidis, Nora-Athina Viniou

“…The following is a review focusing on the present knowledge about single gene/gene promoter methylation or mRNA expression in CLL cases as well as records of older data that have been published in past papers.…”
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A human pathogenic hantavirus circulates and is shed in taxonomically diverse rodent reservoirs. by Samuel M Goodfellow, Robert A Nofchissey, Chunyan Ye, Jaecy K Banther-McConnell, Thanchira Suriyamongkol, Joseph A Cook, Jonathan L Dunnum, Ivana Mali, Steven B Bradfute

“…<h4>Background</h4>Orthohantaviruses are negative-sense RNA viruses that can cause hantavirus cardiopulmonary syndrome (HCPS) in humans. …”
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Expanding Viral Diversity in Rice Fields by Next-Generation Sequencing by Wang Haoran, Chen Guoqing, Feng Guozhong

“…Many novel viruses have been discovered in rice ecosystems through NGS technologies, with some also detected using metatranscriptomic and small RNA sequencing. These analyses greatly expand our understanding of viruses in rice fields and provide valuable insights for developing efficient strategies to manage insect pests and virus-mediated rice diseases.…”
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The Survivin −31 Snp in Human Colorectal Cancer Correlates with Survivin Splice Variant Expression and Improved Overall Survival by Anna G. Antonacopoulou, Konstantina Floratou, Vasiliki Bravou, Anastasia Kottorou, Fotinos-Ioannis Dimitrakopoulos, Stella Marousi, Michalis Stavropoulos, Agelos K. Koutras, Chrisoula D. Scopa, Haralabos P. Kalofonos

“…In the present study, the mRNA levels of the five known isoforms of survivin as well as survivin protein were assessed in matched normal and neoplastic colorectal tissue. …”
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Dysregulation of the Autophagy-Endolysosomal System in Amyotrophic Lateral Sclerosis and Related Motor Neuron Diseases by Asako Otomo, Lei Pan, Shinji Hadano

“…More than 16 causative genes for ALS/MNDs have been identified and their underlying pathogenesis, including oxidative stress, endoplasmic reticulum stress, excitotoxicity, mitochondrial dysfunction, neural inflammation, protein misfolding and accumulation, dysfunctional intracellular trafficking, abnormal RNA processing, and noncell-autonomous damage, has begun to emerge. …”
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Ultra-sensitive fluorescence-activated droplet single-cell sorting based on Tetramer-HCR-EvaGreen amplification by Long Chen, Yi Xu, Lele Zhou, Ding Ma, Rong Zhang, Yifan Liu, Xianqiang Mi

“…The sorted MCF-7 cells showed similar proliferation together with CK19 and EGFR mRNA expression compared with the control cells. …”
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NFAT5 Contributes to Osmolality-Induced MCP-1 Expression in Mesothelial Cells by Christoph Küper, Franz-X. Beck, Wolfgang Neuhofer

“…Hyperosmolality, induced by addition of glucose, NaCl, or mannitol to the growth medium, increased NFAT5 activity and stimulated MCP-1 expression in Met5A cells. siRNA-mediated knockdown of NFAT5 attenuated osmolality-induced MCP-1 upregulation substantially. …”
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Effect of Hemin on Brain Alterations and Neuroglobin Expression in Water Immersion Restraint Stressed Rats by Merhan Ragy, Fatma Ali, Maggie M. Ramzy

“…Stress hormones, oxidative stress markers, malondialdehyde (MDA), and total antioxidant capacity (TAC) were measured and expressions of neuroglobin and S100B mRNA in brain tissue were assayed. Our results revealed that hemin significantly affects brain alterations induced by acute stress and this may be through increased expression of neuroglobin and through antioxidant effect. …”
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Effect of dietary Cucurbita pepo extract on performance, hemato-immunological parameters, immune-related gene expression and bacterial resistance in rainbow trout, Oncorhynchus myk... by Kaveh Vakili, Amir Eghbal Khajehrahimi, Behnam Salimi, Shapour Kakoolaki, Arman Ghorbanzadeh

“…Furthermore, the highest mRNA level of tumor necrosis factor (TNF-α) was observed in 4 % CPE diet. …”
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Research progress of circRNAs in bone-related diseases by Xianming Hua, Lingfeng Yu, Hao Zhu, Yan Zhu, Gentao Fan, Guangxin Zhou, Guangxin Zhou, Guangxin Zhou

“…This review summarizes the advancements in circRNA detection techniques and the research progress of circRNAs in orthopedic diseases.…”
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Pharmaceutical approaches for COVID-19: An update on current therapeutic opportunities by Fan Sijia, Wang Hongling, Wu Dean, Liu Lu

“…Various natural compounds such as sarsapogenin, lycorine, biscoclaurine, vitamin B12, glycyrrhizic acid, riboflavin, resveratrol and kaempferol, various vaccines and drugs such as AZD1222, mRNA-1273, BNT162b2, Sputnik V, and remdesivir, lopinavir, favipiravir, darunavir, oseltamivir, and umifenovir, resp., have been discussed comprehensively. …”
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The Expression of MMP-2 Following Immobilization and High-Intensity Running in Plantaris Muscle Fiber in Rats by Eli Carmeli, Tal Gal Haimovitch

“…High-intensity running and immobilization increased both mRNA and protein levels of matrix metalloproteinase type 2 (MMP-2) in plantaris. …”
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