Showing 281 - 300 results of 5,293 for search '"RNA"', query time: 0.07s Refine Results
  1. 281
  2. 282

    CircRNA-Disease Associations Prediction Based on Metapath2vec++ and Matrix Factorization by Yuchen Zhang, Xiujuan Lei, Zengqiang Fang, Yi Pan

    Published 2020-12-01
    “…Circular RNA (circRNA) is a novel non-coding endogenous RNAs. …”
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    Article
  3. 283

    circRNA Expression Profile in Dental Pulp Stem Cells during Odontogenic Differentiation by Ming Chen, Yeqing Yang, Junkai Zeng, Zilong Deng, Buling Wu

    Published 2020-01-01
    “…Recent studies showed that circular RNAs (circRNAs) have many biological functions and that competing endogenous RNA (ceRNA) is their most common mechanism of action. …”
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    Article
  4. 284
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    Simultaneous Detection of Different MicroRNA Types Using the ZIP-Code Array System by Sonja U. Weishaupt, Steffen Rupp, Karin Lemuth

    Published 2013-01-01
    “…DNA microarrays are predestinated as a high-throughput method for comprehensive miRNA detection in tumors. However, the simultaneous array-based detection of both these miRNA types is limited because the mature miRNA sequence is identically present in both forms. …”
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    Article
  6. 286

    Telomerase RNA structural heterogeneity in living human cells detected by DMS-MaPseq by Nicholas M. Forino, Jia Zheng Woo, Arthur J. Zaug, Arcelia Gonzalez Jimenez, Eva Edelson, Thomas R. Cech, Silvi Rouskin, Michael D. Stone

    Published 2025-01-01
    “…Abstract Biogenesis of human telomerase requires its RNA subunit (hTR) to fold into a multi-domain architecture that includes the template-pseudoknot (t/PK) and the three-way junction (CR4/5). …”
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    Article
  7. 287

    lncRNA FR215775 Regulates Th2 Differentiation in Murine Allergic Rhinitis by Yue Ma, Le Shi, Keqing Zhao, Chunquan Zheng

    Published 2022-01-01
    “…To identify the effect of long noncoding RNA (lncRNA) FR215775 in regulating CD4+ T cells on murine models of allergic rhinitis (AR), the expression of lncRNA FR215775 in primary Th2 cells was detected through qRT-PCR. …”
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  8. 288

    A hammerhead ribozyme selects mechanically stable conformations for catalysis against viral RNA by Man Lu, Zhiqiang Cao, Luoan Xiong, Hongying Deng, Kangkang Ma, Ning Liu, Yanding Qin, Shen-Bo Chen, Jun-Hu Chen, Yao Li, Yijin Liu, Zhongbo Yu

    Published 2025-02-01
    “…Our understanding of the RNA catalytic mechanism will be beneficial for ribozyme’s biotechnological applications and as potential therapeutics against RNA viruses.…”
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    Structural basis for RNA-guided DNA degradation by Cas5-HNH/Cascade complex by Yanan Liu, Lin Wang, Qian Zhang, Pengyu Fu, Lingling Zhang, Ying Yu, Heng Zhang, Hongtao Zhu

    Published 2025-02-01
    “…Abstract Type I-E CRISPR (clustered regularly interspaced short palindromic repeats)–Cas (CRISPR-associated proteins) system is one of the most extensively studied RNA-guided adaptive immune systems in prokaryotes, providing defense against foreign genetic elements. …”
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  13. 293

    Small Interfering RNA Targeted to ASPP2 Promotes Progression of Experimental Proliferative Vitreoretinopathy by Xiao-Li Chen, Yu-Jing Bai, Qin-Rui Hu, Shan-Shan Li, Lv-Zhen Huang, Xiao-Xin Li

    Published 2016-01-01
    “…ARPE-19 cells were transfected with ASPP2-siRNA, followed with measurement of cell cytotoxicity, proliferation, and migration ability. …”
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  14. 294

    Clinical Significance and Pathogenic Mechanisms of Long Non-Coding RNA TRPM2-AS in Cancers by Shichen Huang MS, Bowen Li MS, Huanyu Chen MD, Cheng Rong, Zheng Yang MD, Xianqin Zhang PhD

    Published 2025-01-01
    “…Long non-coding RNAs (lncRNAs) are known to play vital roles in human cancers. LncRNA TRPM2-AS has been found to be upregulated in various types of cancers. …”
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  15. 295

    A continuous phenotype space model of RNA virus evolution within a host by Andrei Korobeinikov, Conor Dempsey

    Published 2014-02-01
    “…Due to their very high replication and mutation rates, RNA virusescan serve as an excellent testing model for verifying hypothesis andaddressing questions in evolutionary biology.In this paper, we suggest a simple deterministic mathematical modelof the within-host viral dynamics, where a possibility for random mutations incorporates.This model assumes a continuous distribution of viral strainsin a one-dimensional phenotype space where random mutations aremodelled by Brownian motion (that is, by diffusion).Numerical simulations show that randommutations combined with competition for a resource result in evolutiontowards higher Darwinian fitness: a stable pulse traveling waveof evolution, moving towards higher levels of fitness,is formed in the phenotype space.The advantage of this model, compared with the previously constructedmodels, is that this model is mechanistic and is based on commonlyaccepted model of virus dynamics within a host, and thus it allowsan incorporation of features of the real-life host-virus system such as immuneresponse, antiviral therapy, etc.…”
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    Comparison of the MGISEQ-2000 and Illumina HiSeq 4000 sequencing platforms for RNA sequencing by Sol A Jeon, Jong Lyul Park, Jong-Hwan Kim, Jeong Hwan Kim, Yong Sung Kim, Jin Cheon Kim, Seon-Young Kim

    Published 2019-09-01
    “…In this study, we compared the performance of two major sequencers (MGISEQ-2000 and HiSeq 4000) to test whether the MGISEQ-2000 sequencer delivers high-quality sequence data as suggested. We performed RNA sequencing of four human colon cancer samples with the two platforms, and compared the sequencing quality and expression values. …”
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    Reduced UPF1 levels in senescence impair nonsense-mediated mRNA decay by Dahyeon Koh, Yebin Lee, Kyuchan Kim, Hyeong Bin Jeon, Chaehwan Oh, Sangik Hwang, Minjung Lim, Kwang-Pyo Lee, Yeonkyoung Park, Yong Ryoul Yang, Yoon Ki Kim, Donghwan Shim, Myriam Gorospe, Ji Heon Noh, Kyoung Mi Kim

    Published 2025-01-01
    “…Nonsense-mediated mRNA decay (NMD), a well-characterized RNA surveillance mechanism, degrades aberrant mRNAs with premature termination codons (PTCs) to prevent the synthesis of truncated proteins. …”
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  20. 300

    D-stem mutation in an essential tRNA increases translation speed at the cost of fidelity. by Madison N Schrock, Krishna Parsawar, Kelly T Hughes, Fabienne F V Chevance

    Published 2025-02-01
    “…The efficiency with which aminoacyl-tRNA and GTP-bound translation elongation factor EF-Tu recognizes the A-site codon of the ribosome is dependent on codons and tRNA species present in the polypeptide (P) and exit (E) codon sites. …”
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