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2841
Molecular Mechanisms Regulating Hepcidin Revealed by Hepcidin Disorders
Published 2011-01-01“…To avoid iron overload and maintain iron homeostasis, all cells are able to regulate their iron content through the post-transcriptional control of iron genes operated by the cytosolic iron regulatory proteins that interact with iron responsive elements on iron gene mRNA. At the systemic level, iron homeostasis is regulated by the liver peptide hepcidin. …”
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2842
Genomic Analysis Methods of Microorganisms
Published 2025-01-01“…Molecular approaches used to identify bacterial species use 16S rRNA and MLST to determine the genetic linkage of bacteria; MLST characterizes clonal linkages by examining differences in various gene loci. …”
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2843
Enteric Fever as an Antecedent to Development of Miller-Fisher Syndrome and Possible Role of COVID-19 Vaccination
Published 2023-12-01“…We conclude that Miller-Fisher syndrome should be considered in the diagnostic workup of patients presenting with new sensorimotor deficits following diarrheal illnesses and/or COVID-19 mRNA vaccination. Early recognition is essential given the propensity of GBS to cause life-threatening respiratory failure and prompt IVIG administration is associated with a better prognosis. …”
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2844
MYC Negative Rectal B-Cell Lymphoma, Unclassifiable, with Features Intermediate between Diffuse Large B-Cell Lymphoma and Burkitt’s Lymphoma in an Immunocompetent Patient
Published 2013-01-01“…We report the first case of rectal BLUI/BLL in an immunocompetent patient who is also negative for MYC abnormalities and the EBV early RNA (EBER) in situ hybridization.…”
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2845
Epigenetic Dynamics: Role of Epimarks and Underlying Machinery in Plants Exposed to Abiotic Stress
Published 2014-01-01“…We present a lucid review of epigenetic machinery and epigenetic alterations involving DNA methylation, histone tail modifications, chromatin remodeling, and RNA directed epigenetic changes.…”
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2846
Pilot Study of Ofloxacin and Interferon-Alpha Combination Therapy for Chronic Hepatitis C without Sustained Response to Initial Interferon Therapy
Published 1997-01-01“…Levels of hepatitis C virus RNA declined significantly from the first month after the start of IFN treatment compared with those before administration in both groups. …”
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2847
Role of microRNAs in Stroke and Poststroke Depression
Published 2013-01-01“…microRNAs (miRNA), a sort of noncoding RNAs widely distributed in eukaryotic cells, could regulate gene expression by inhibiting transcription or translation. …”
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2848
INTESTINAL MICROBIOME - A LEADING FACTOR IN HUMAN HEALTH AND DISEASES
Published 2018-08-01“…On the other hand, high throughput array and other technologies made it possible to simultaneously analyze thousands of genes (DNA) or gene products (RNA and proteins), resulting in an individual gene or gene expression profile (‘signature’) or to characterize the individual microbiome and its pathogenetic potential. …”
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2849
Olfm4 Is Highly Expressed in HCC Patients and as a Biomarker and Therapeutic Target for HCC
Published 2021-01-01“…Furthermore, HCC patients also have higher messenger ribonucleic acid (mRNA) expression level in HCC tissues than in liver paracancerous tissues. …”
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2850
Influenza Viral Manipulation of Sphingolipid Metabolism and Signaling to Modulate Host Defense System
Published 2014-01-01“…The mechanism involves regulation of intracellular signaling pathways, leading to the amplification of influenza viral RNA synthesis and nuclear export of viral ribonucleoprotein (RNP) complex. …”
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2851
MicroRNAs in Cerebral Ischemia
Published 2013-01-01“…Current studies found that microRNAs (miRNAs or miRs) are also closely related to the pathological process of stroke. miRNAs are a group of short, noncoding RNA molecules playing important role in posttranscriptional regulation of gene expression and they have emerged as regulators of ischemic preconditioning and ischemic postconditioning. …”
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2852
COVID-19: An overview on possible transmission ways, sampling matrices and diagnosis
Published 2024-11-01“…COVID-19 is an RNA virus belonging to the SARS family of viruses and includes a wide range of symptoms along with effects on other body organs in addition to the respiratory system. …”
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2853
Research progress on the role of extracellular vesicles in the pathogenesis of diabetic kidney disease
Published 2024-12-01“…Extracellular vesicles (EVs) contain cell-derived membrane proteins, nucleic acids (such as DNA and RNA) and other important cellular components and are involved in intercellular information and substance transmission. …”
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2854
Shortening of 3'UTRs correlates with poor prognosis in breast and lung cancer.
Published 2012-01-01“…Proliferating cells partly escape this type of negative regulation by expressing shorter 3' UTRs, depleted of microRNA binding sites, compared to non-proliferating cells. …”
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2855
In Vitro Comparison of the Internal Ribosomal Entry Site Activity from Rodent Hepacivirus and Pegivirus and Construction of Pseudoparticles
Published 2021-01-01“…Utilizing a monocistronic expression vector with an RNA polymerase I promoter to drive transcription, we show cell-specific IRES translation and regions within the IRES required for full functionality. …”
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2856
The Emerging Perspective of Morphine Tolerance: MicroRNAs
Published 2019-01-01“…This review covers some of the most striking microRNA functions involved in morphine tolerance and presents limitations on our knowledge of their physiological roles.…”
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2857
Exacerbating Guillain–Barré Syndrome Eight Days after Vector-Based COVID-19 Vaccination
Published 2021-01-01“…Since the introduction of mRNA technology-based and vector-based COVID-19 vaccines, adverse reactions to these agents have been occasionally reported. …”
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2858
Sex differences in murine MASH induced by a fructose-palmitate-cholesterol-enriched diet
Published 2025-02-01“…At sacrifice, plasma and liver were retrieved, the latter for single-nucleus RNA sequencing. Publicly available data sets of human male and female MASH liver were probed. …”
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2859
Responses of Phospholipase D and Antioxidant System to Mechanical Wounding in Postharvest Banana Fruits
Published 2017-01-01“…The higher value of PLD mRNA was found in wounded fruits than in control. …”
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2860
IL-1 Receptor Antagonist Protects the Osteogenesis Capability of Gingival-Derived Stem/Progenitor Cells under Inflammatory Microenvironment Induced by Porphyromonas gingivalis Lipo...
Published 2021-01-01“…These negative effects were effectively attenuated by IL-1ra administration in a time- and dose-dependent manner. In addition, mRNA expressions of TLR4 and IkBα decreased dramatically when IL-1ra was added into LPS-induced medium. …”
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